Tag: M.W=500-600

2043-53-0, name is 1-Iodo-1H,1H,2H,2H-perfluorodecane, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Safety of 1-Iodo-1H,1H,2H,2H-perfluorodecane

General procedure: Perfluoroalkylethyl iodide (1.0 mol equiv.) (3-4 mmol) and NaN3 (1.2 mol equiv.) were added to dry DMSO (2 mL) in a 10 mL CEM microwave glass reactor tube, a magnetic stirring bead added and the system sealed. The tube was subjected to stirring and microwave irradiation at 250 W and 65 C for 1 h then immediately cooled to r.t.

The synthetic route of 2043-53-0 has been constantly updated, and we look forward to future research findings.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2043-53-0, name is 1-Iodo-1H,1H,2H,2H-perfluorodecane, This compound has unique chemical properties. The synthetic route is as follows., name: 1-Iodo-1H,1H,2H,2H-perfluorodecane

To a solution of 1H,1H,2H,2H-perfluoro-1-iododecane (8.0 g, 14 mmol) in dry ether (150 ml) at -78 C. under Ar was added t-BuLi (1.7 M in hexane; 35 ml, 21 mmol) dropwise with stirring. The mixture was stirred for 1.5 h at -78 C. and cholodiisopropylrosilane (1.7 ml, 10 mmol) was added to the reaction mixture dropwise. The mixture was stirred for 3 h and then warmed to ambient temperature. The reaction mixture was quenched with saturated NH4Cl aqueous solution and extracted with ether. The extract was dried over anhydrous MgSO4 and concentrated. The dark red liquid residue was passed through short column chromatography on silica gel with hexane to provide diisopropyl-1H,1H,2H,2H-perfluorodecanylsilane in 95% yield (5.3 g, 9.5 mmol) as a colorless liquid.

According to the analysis of related databases, 2043-53-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; University of Pittsburgh; US6897331; (2005); B2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 35453-19-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 35453-19-1, name is 5-Amino-2,4,6-triiodoisophthalic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Synthesis of 5-Amino-2,4,6-triiodo-isophthaloyl dichloride (1)5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol) (commercially available from Aldrich), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 0C. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during VA to 2 hrs, and the mixture was heated to 85 0C for 6 hrs. After cooling the reaction mixture to room temperature, it was poured into 30Og of ice-water. The yellow precipitate that formed was filtered off, air dried and then washed with water until washings showed a pH of ca 5. The filter cake was then dried in a vacuum oven at 5O0C for 3 hrs. A light yellow powder was obtained 31 g (~ quant.) as the desired product.13C NMR (DMSOd6) 66, 78.4, 148.9, 149.2, 169MS (ES-) found 593.5 [M-H+], expected 593.7

The synthetic route of 5-Amino-2,4,6-triiodoisophthalic acid has been constantly updated, and we look forward to future research findings.

Reference:
Patent; GE HEALTHCARE AS; WO2009/5365; (2009); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 35453-19-1, The chemical industry reduces the impact on the environment during synthesis 35453-19-1, name is 5-Amino-2,4,6-triiodoisophthalic acid, I believe this compound will play a more active role in future production and life.

5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol) (commercially available from Aldrich), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 0C. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during 11/4 to 2 hrs, and the mixture was heated to 85 0C for 6 hrs. After cooling the reaction mixture to room temperature, it was poured into 30Og of ice-water. The yellow precipitate that formed was filtered off, sucked dry and then washed with water until washings showed a pH of ca 5. The filter cake was then dried in a vacuum oven at 500C for 3 hrs. A light yellow powder was obtained 31 g (~ quant.) as the desired product. 13C NMR (DMSOd6) 66, 78.4, 148.9, 149.2, 169 MS (ES-) found 593.5 [M-H+], expected 593.7

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Amino-2,4,6-triiodoisophthalic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; GE HEALTHCARE AS; WO2008/123779; (2008); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chemistry, like all the natural sciences, Name: Heptadecafluoro-1-iodooctane, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is Lin, Weiying, introduce the new discover.

A fluorescence turn-on probe for iodide based on the redox reaction between cupric and iodide

We have Successfully introduced a novel strategy for the rational design of a fluorescence turn-on probe for iodide, which is a notorious fluorescence quencher clue to the heavy atom effect. The strategy is based oil the redox reaction between Cu(2+) and iodide. The probe exhibited a 20-fold fluorescence enhancement ill the presence of 4 equiv. of iodide. The probe developed herein represents the first fluorescence amplified probe for iodide. We believe that it will find interesting use ill environment. (C) 2009 Elsevier B.V. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 507-63-1. Name: Heptadecafluoro-1-iodooctane.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I. In an article, author is Masuyama, Yoshiro,once mentioned of 507-63-1, SDS of cas: 507-63-1.

Aldol reactions of alpha-bromoalkyl phenyl ketones and aldehydes with Tin(IV) iodide and tetrabutylammonium iodide

Aldol reactions of alpha-bromoacetophenone and aldehydes in dichloromethane produced the corresponding E-alpha,beta-unsaturated ketones at 25 degrees C with one equimolar amount of tin(IV) iodide, one equimolar amount of tetrabutylammonium iodide and one equimolar amount of N,N-diisopropylethylamine, and produced the corresponding beta-hydroxy ketones at -80 degrees C with one equimolar amount of tin(IV) iodide and two equimolar amounts of tetrabutylammonium iodide. Using one equimolar amount of tin(IV) iodide and two equimolar amounts of tetrabutylammonium iodide at -80 degrees C in dichloromethane, alpha-bromopropiophenone reacted with aldehydes to afford the corresponding syn-alpha-methyl-beta-hydroxy ketones selectively.

Interested yet? Keep reading other articles of 507-63-1, you can contact me at any time and look forward to more communication. SDS of cas: 507-63-1.

Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is Heigel, E, introduce the new discover, Safety of Heptadecafluoro-1-iodooctane.

Bis(2-chloro-N-methylpyridinium) iodide triiodide

The title compound, 2C(6)H(7)ClN+I-.I-,(3) Y, crystallizes with undulating layers of chains containing alternate iodide and triiodide anions formed from iodine and the heterocyclic iodide salt.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 507-63-1 is helpful to your research. Safety of Heptadecafluoro-1-iodooctane.

Chemistry is an experimental science, Application In Synthesis of Heptadecafluoro-1-iodooctane, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, belongs to iodides-buliding-blocks compound. In a document, author is Randle, Reese W..

Impact of potassium iodide on thyroidectomy for Graves’ disease: Implications for safety and operative difficulty

Background. Potassium iodide often is prescribed prior to thyroidectomy for Graves’ disease, but the effect of potassium iodide on the ease and safety of thyroidectomy for Graves’ is largely unknown. Methods. We conducted a prospective, cohort study of patients with Graves’ disease undergoing thyroidectomy. For the first 8 months, no patients received potassium iodide; for the next 8 months, potassium iodide was added to the preoperative protocol for all patients. Outcomes included operative difficulty (based on the Thyroidectomy Difficulty Scale) and complications. Results. We included a total of 31 patients in the no potassium iodide group and 28 in the potassium iodide group. According to the Thyroidectomy Difficulty Scale, gland vascularity decreased in the potassium iodide group (mean score 2.6 vs 3.3, P = .04), but there were no differences in friability, fibrosis, or size of the thyroid or in overall difficulty of operation (P = not significant for all). Despite similar operative difficulty, patients prescribed potassium iodide were less likely to experience transient hypoparathyroidism (7% vs 26%, P = .018) and transient hoarseness (0% vs 16%, P = .009) compared with the no potassium iodide group. Conclusion. Potassium iodide administration decreases gland vascularity, but does not change the overall difficulty of thyroidectomy. Preoperative use of potassium iodide solution was, however, associated with less transient hypoparathyroidism and transient hoarseness, suggesting that potassium iodide improves the safety of thyroidectomy for Graves’ disease. (C) 2017 Elsevier Inc. All rights reserved.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 507-63-1. Application In Synthesis of Heptadecafluoro-1-iodooctane.

Chemistry, like all the natural sciences, Formula: C8F17I, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is FANELLI, A, introduce the new discover.

INHIBITION OF IODIDE TRANSPORT IN RAT-THYROID CELLS USING N-SUBSTITUTED ANTHRANILIC ACID-DERIVATIVES

The purpose of this study was to test the effects of chloride channel blockers on iodide uptake in thyroid cells, in the hope of eventually using these blockers to identify and isolate a putative iodide transporter, The chloride channel blockers used in this report are derivatives of N-substituted anthranilic acid and were synthesized using published procedures, For these studies FRTL-5 cells, a line of continuous-growing rat thyroid cells, were used as a model system to study effects on iodide transport. In these cells, there are at least two ways for transmembrane iodide movements, a sodium-dependent influx step and a proposed channel that normally mediates iodide efflux, Two derivatives studied decreased iodide accumulation in FRTL-5 cells, but were found also to lower intracellular pH and ATP levels, To simplify interpretation of the effect of the drugs on iodide transport, we extended the studies using plasma membrane vesicles made from pig thyroid, Iodide entry in these vesicles depended on a sodium gradient and was independent of ATP levels, Iodide transport in plasma membrane vesicles and FRTL-5 cells was measured at 30 sec when the uptake was nearly linear and therefore likely to reflect iodide entry, The uptake was measured using three concentrations of iodide and three of drug. Kinetic analysis of the data described a competitive inhibition by the drugs with a K-i of approximately 250 mu M. In summary, N-substituted anthranilic acid derivatives reversibly inhibit iodide entry in FRTL-5 cells and pig plasma membrane vesicles, Because of their ease of synthesis and modification, these derivatives are potentially useful probes for isolation of the NaI symporter in thyroid.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 507-63-1. Formula: C8F17I.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Shkadauskene, OP, once mentioned the new application about 507-63-1, Safety of Heptadecafluoro-1-iodooctane.

Determination of iodide using the oxidation of o-dianisidine by chloramine B in acid solutions

A method was developed for the kinetic determination of iodides. The method is based on the promoting effect of iodides on the oxidation of a-dianisidine by Chloramine B in hydrochloric acid solutions. The detection limit of the method is 4 x 10(-4) mu g/mL. It was demonstrated that this method can be employed for the determination of iodides in fresh waters. Iodates and periodates do not interfere with the determination of iodides when both of them are present.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 507-63-1. The above is the message from the blog manager. Safety of Heptadecafluoro-1-iodooctane.