Tag: M.W=250-300

Al-Zahrani, Fatimah A. M. published the artcileSynthesis, Dynamics of Solvatochromism and pH-sensory of Novel Push-π-pull Phenothiazine-quinoline Fluorophore Toward Turn-on Fluorescent and Colorimetric Test Strips, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Fibers and Polymers (2022), 23(5), 1182-1189, database is CAplus.

Novel donor-central-π-bridge-acceptor (E)-1-ethyl-2-((10-hexyl-10H-phenothiazin-3-yl)methylene)-2,4a-dihydroquinolin-1-ium (PTZ-Q) fluorophore with remarkable solvatochromism, high fluorescence and pH-sensory properties was designed and synthesized in good yield. PTZ-Q sensor was fully characterized utilizing various spectroscopic techniques, including IR (FTIR), ¹H/¹³C NMR, and mass spectroscopic methods. UV-Vis absorption spectra of the prepared donor-acceptor PTZ-Q were explored in different solvents of varying polarities to show pos. solvatochromism related to intramol. charge transfer. Addnl., the fluorescence spectra of PTZ-Q displayed strongly solvent-dependent wavelength and band intensity. Stokes′ shifts were found to increase upon increasing the polarities of solvents up to 3984 cm^-1 for the highest polar solvents. Linear energy-solvation correlation was employed to examine solvent-dependent Stokes′ shift. Quantum yields () of PTZ-Q were determined The pH-dependent absorption and emission spectra in DMF were also explored. The UV-Vis absorption intensity was monitored at 522 nm, while the emission intensity was detected at 603 nm in DMF. The pH sensing mechanism was found to depend on proton abstraction to the PTZ-Q fluorophore to result in colorimetric and fluorescent spectral changes associated with a colorimetric shift from yellow to pink, red and purple. The synthesized PTZ-Q probe was utilized to fabricate colorimetric and fluorescent test strips with the ability to detect pH changes in aqueous media, which was verified with CIE Lab color coordinates.

Fibers and Polymers published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bagrov, F. V. published the artcileReaction of ethyl ethoxymethyleneacetoacetate with hydrazine monoderivatives, Application of 4-Iodobenzohydrazide, the publication is Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) (2000), 36(2), 191-194, database is CAplus.

The reaction of Et α-ethoxymethyleneacetoacetate with acylhydrazines affords the corresponding acylhydrazones of α-formylacetoacetic ester. The ¹H NMR and IR spectra revealed that the compounds obtained existed in ketoenamine (ketoenhydrazine) form. The condensation of 4-chlorophenyl-, 4-nitrophenyl-, 6-chloropyridazinyl- and 4-phenylphthalazinylhydrazines with the Et ethoxymethyleneacetoacetate is accompanied by cyclization into the corresponding 5-methyl-4-ethoxycarbonylpyrazoles.

Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Application of 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bagrov, F. V. published the artcileCondensation of ethyl (ethoxymethylene)cyanoacetate with acyl- and diphenylphosphinylhydrazines, Related Products of iodides-buliding-blocks, the publication is Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) (2000), 70(3), 422-425, database is CAplus.

Condensation of Et (ethoxymethylene)cyanoacetate with hydrazides of diphenylphosphinic acid and aliphatic and aromatic acids in EtOH involves exclusively the ethoxymethylene group and yields the corresponding Et 3-oxo-2-cyanopropanoate hydrazones. These compounds exist in the crystalline state and in solutions as the enehydrazine tautomer in which the configurational equilibrium is determined by the nature of substituent in the hydrazine moiety.

Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gomaa, Maha Mobaruk published the artcileOxonium heterocyclic quinone in the synthesis of some cyanine dyes and their antimicrobial activity, Formula: C12H14IN, the publication is European Journal of Chemistry (2014), 5(3), 463-468, 6 pp., database is CAplus.

The motivation of the synthetic process of new heterocyclic cyanine dyes is to improve the specific characterization, photosensitization behavior, and probable application in the field of biol., medical science and physics. New heterocyclic compounds having oxonium nuclei were prepared and employed for the synthesis of some new photosensitizers cyanine dyes (monomethine, trimethine and styryl cyanines). The electronic visible absorption spectra of all the synthesized cyanines were investigated in 95% ethanol to attempt and throw some light on the influence of such new heterocyclic nuclei and to compare or evaluate spectral behaviors. Antimicrobial activity of selected compounds against some bacterial strains was tested. Structural identification was carried out via elemental anal., IR and ¹H NMR.

European Journal of Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Formula: C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Haristos, Demetrius A. published the artcileKinetic study of the oxidation of ring monosubstituted aroylhydrazines by copper(II) chloride. Application of the Hammett equation, Formula: C7H7IN2O, the publication is Chimika Chronika (1983), 12(3), 129-35, database is CAplus.

The oxidation kinetics of RC₆H₄CONHNH₂ (I; R = halo, NO₂, MeO) by CuCl₂, to give RC₆H₄CO₂H, was examined at 25-60° and pH 4.40-5.60. The reaction is first-order each in I and CuCl₂; the second order rate constant is inversely proportional to the H⁺ concentration The reaction has ρ – 0.10 with the points for I (R = m – F and p – NO₂) deviating significantly from the LFER. The substituent effect is involved mainly in the ability of I to form complexes with CuCl₂; the substituted effect on the electron transfer rate is negligible.

Chimika Chronika published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Formula: C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Han, Xiaojing published the artcileA FRET-based ratiometric fluorescent probe to detect cysteine metabolism in mitochondria, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Organic & Biomolecular Chemistry (2020), 18(7), 1487-1492, database is CAplus and MEDLINE.

As an important biothiol in living cells, cysteine is closely related to oxidative damage in living organisms. Sulfite from cysteine metabolism in living cells plays a crucial role in maintaining homeostasis in an organism, and the unbalance of sulfite in vivo would lead to multiple diseases. Thus the development of a new fluorescent probe for cysteine metabolism is needed urgently in mitochondria which are the main place of cysteine metabolism Herein the authors construct a novel targeting mitochondria fluorescent probe CP-K (I) based on the FRET mechanism to visualize sulfite in living MCF-7 cells. Probe CP-K displays a large Stokes shift of 150 nm, a low detection limit (26.3 nM) and “naked eye” detection after the addition of HSO₃^–. Importantly, it is appropriate for imaging the endogenous sulfite from cysteine metabolism in living cells.

Organic & Biomolecular Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Han, Jie published the artcileSynthesis and liquid crystalline properties of substituted 2,5-diaryl 1,3,4-oxadiazole derivatives without flexible chains, Recommanded Product: 4-Iodobenzohydrazide, the publication is Liquid Crystals (2008), 35(12), 1359-1365, database is CAplus.

A series of new compounds based on aromatically 2,5-disubstituted 1,3,4-oxadiazoles without flexible chains, formulated as p-R-C6H4-(OC2N2)-(p-C6H4)2-R’ with (i) R = CH3O, R’ = CH3O, CH3S, F, H (Ia-Id), (ii) R = CH3S, R’ = CH3O, CH3S, F, H (IIa-IId) and (iii) R = F, R’ = CH3O, CH3S, F, H (IIIa-IIId) (p-C6H4 and OC2N2 represent a p-phenylene spacer and a 1,3,4-oxadiazole ring, resp.), were synthesized and characterized by ¹H and ¹³C NMR, MS and HRMS techniques. Mesomorphic properties were investigated using differential scanning calorimetry and polarizing optical microscopy. All of the target compounds (except Id, IId, IIIc and IIId) exhibited an enantiotropic nematic mesophase with high melting temperatures The liquid crystalline properties of these compounds were influenced greatly by polarity, steric factors and positions of the terminal groups. The effect of the terminal groups on the liquid crystal properties is discussed.

Liquid Crystals published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Recommanded Product: 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Eunkyung published the artcileIntegration of Cyanine, Merocyanine and Styryl Dye Motifs with Synthetic Bacteriochlorins, Application In Synthesis of 606-55-3, the publication is Photochemistry and Photobiology (2016), 92(1), 111-125, database is CAplus and MEDLINE.

Understanding the effects of substituents on spectral properties is essential for the rational design of tailored bacteriochlorins for light-harvesting and other applications. Toward this goal, three new bacteriochlorins containing previously unexplored conjugating substituents have been prepared and characterized. The conjugating substituents include two pos. charged species, 2-(N-Et 2-quinolinium)vinyl- (B-1) and 2-(N-Et 4-pyridinium)vinyl- (B-2), and a neutral group, acroleinyl- (B-3); the charged species resemble cyanine (or styryl) dye motifs whereas the neutral unit resembles a merocyanine dye motif. The three bacteriochlorins are examined by static and time-resolved absorption and emission spectroscopy and d. functional theor. calculations B-1 and B-2 have Q_y absorption bathochromically shifted well into the NIR region (822 and 852 nm), farther than B-3 (793 nm) and other 3,13-disubstituted bacteriochlorins studied previously. B-1 and B-2 have broad Q_y absorption and fluorescence features with large peak separation (Stokes shift), low fluorescence yields, and shortened S₁ (Q_y) excited-state lifetimes (∼700 ps and ∼100 ps). More typical spectra and S₁ lifetime (∼2.3 ns) are found for B-3. The combined photophys. and mol.-orbital characteristics suggest the altered spectra and enhanced nonradiative S₁ decay of B-1 and B-2 derive from excited-state configurations in which electron d. is shifted between the macrocycle and the substituents.

Photochemistry and Photobiology published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C10H15ClO3S, Application In Synthesis of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Yuanfei published the artcileCarboxylic Acids as Traceless Directing Groups for the Rhodium(III)-Catalyzed Decarboxylative C-H Arylation of Thiophenes, Computed Properties of 145343-76-6, the publication is Angewandte Chemie, International Edition (2015), 54(12), 3817-3821, database is CAplus and MEDLINE.

A rhodium(III)-catalyzed carboxylic acid directed decarboxylative C-H/C-H cross-coupling of carboxylic acids with thiophenes was developed. With a slight adjustment of the reaction conditions based on the nature of the substrates, arylcarboxylic acids with a variety of substituents served as suitable coupling partners, and a broad variety of functional groups were tolerated. The method provided straightforward access to biaryl scaffolds with diverse substitution patterns, many of which have conventionally been synthesized through lengthy synthetic sequences. An illustrative example was the one-step gram-scale synthesis of biol. active I from 2-(4-methoxyphenyl)thiophene and 2-methoxy-4-methylbenzoic acid.

Angewandte Chemie, International Edition published new progress about 145343-76-6. 145343-76-6 belongs to iodides-buliding-blocks, auxiliary class Chloride,Iodide,Carboxylic acid,Benzene, name is 2-Chloro-4-iodobenzoic acid, and the molecular formula is C9H9F5Si, Computed Properties of 145343-76-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Han, Qian published the artcileA redox-switchable colorimetric probe for “Naked-Eye” detection of hypochlorous acid and glutathione, Synthetic Route of 606-55-3, the publication is Molecules (2019), 24(13), 2455, database is CAplus and MEDLINE.

We report the development of a new colorimetric probe (L-ol) for investigations of the redox process regulated by hypochlorous acid (HOCl) and glutathione (GSH). The HOCl/GSH redox-switching cycle process was investigated in detail by UV-visible absorption spectroscopy, colorimetric anal. assay and high-resolution mass spectrometry (HRMS). The switchable absorbance responses were attributed to the HOCl-induced oxidation of the p-methoxyphenol unit to the benzoquinone derivative (L-one) and sequential reduction of L-one to hydroquinone (L-ol’) by GSH. In phosphate-buffered saline (PBS) buffer, the absorbance of L-ol at 619 nm underwent a remarkable bathochromic-shift, accompanied by a color change from pale yellow to blue in the presence of HOCl. With further addition of GSH, the absorbance of L-one exclusively recovered to the original level. Meanwhile, the blue-colored solution returned to the naive pale yellow color in the presence of GSH. The detection limits for HOCl and GSH were calculated to be 6.3 and 96 nM according to the IUPAC criteria. Furthermore, L-ol-loaded chromatog. plates have been prepared and successfully applied to visualize and quant. analyze HOCl in several natural waters.

Molecules published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Synthetic Route of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com