Tag: M.W=250-300

Tian, Tao published the artcileMolecular full-adder and full-subtractor logic circuit based on fluorescein derivatives, COA of Formula: C12H14IN, the publication is Gaodeng Xuexiao Huaxue Xuebao (2015), 36(2), 260-266, database is CAplus.

Over the past decade, there has been significant progress in the development of mol. computer, which has inspired scientists to construct appropriate mol. systems that could integrate simple logic gates into combinatorial circuits. In this work, a novel fluorescein-based QHF⁺ with five-state mol. switch was synthesized. The conversion of the five states of QHF⁺ was observed by UV-visible absorption spectra under various pH values in CH₃CH₂OH/H₂O (volume ratio 1:1). Spectral responses with the use of chem. inputs in the form of H⁺ and OH^– revealed that QHF could function as a combinatorial logic circuit (XOR gate and INHIBIT gate, AND gate and XOR gate). Absorbance change at 424 and 490 nm or transmittance change at 424 nm, was monitored as output signals with threshold value of A=0.209 (or T=61.8%). When absorbance intensity or transmittance percentage was more than the threshold value, the output signal was 1. Otherwise, the output value was 0. In conclusion, a full-subtractor was achieved by setting the initial state to QHF⁰ with outputs at 424 and 490 nm in the absorption mode, while a mol. full-adder was provided by setting the initial state to QHF⁺ and observing both absorbance at 490 nm and transmittance at 424 nm.

Gaodeng Xuexiao Huaxue Xuebao published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C5H5NO3S, COA of Formula: C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Qing published the artcileNovel water soluble styrylquinolinium boronic acid as a ratiometric reagent for the rapid detection of hypochlorite ion, Application of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Dyes and Pigments (2013), 99(3), 733-739, database is CAplus.

A novel water soluble styrylquinolinium boronic acid (I) was synthesized in good yield. A selective oxidation of the C-B bond of the dye by hypochlorite was observed During the oxidation of the dye, the replacement of the strong electron-withdrawing group (-BOH₂) by the electron-donating group (-OH) on the fluorophore resulted in a large red shift of the absorption and emission spectra due to the intramol. charge-transfer process. Based on the oxidation induced intramol. charge-transfer mechanism, the application of the dye as a ratiometric optical chemosensor for ClO^– was studied. It exhibited high selectivity for ClO^– anions over other relevant metal ions, anions and highly reactive oxygen species. Meanwhile, the fast oxidation event along with the characterized color changes allowed the dye to be developed as selective visual chemosensor for ClO^–.

Dyes and Pigments published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C7H6Cl2, Application of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Xicun published the artcileAn expeditious and solvent-free approach to substituted bis-thioureas and bis-thiosemicarbazides, COA of Formula: C7H7IN2O, the publication is Journal of Chemical Research (2005), 791-792, database is CAplus.

An expeditious, high-yield and green approach to substituted bis-thioureas and bis-thiosemicarbazides by grinding the mixture of pyridine-2,6-dicarbonyl dichloride with ammonium thiocyanate and aryl amines or aroyl hydrazines at room temperature under solvent-free condition via one-pot procedure is described.

Journal of Chemical Research published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C4H10O2, COA of Formula: C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Xicun published the artcileSynthesis of substituted 1,3,4-oxadiazoles under microwave irradiation, COA of Formula: C7H7IN2O, the publication is Phosphorus, Sulfur and Silicon and the Related Elements (2006), 181(3), 627-630, database is CAplus.

A series of substituted 1,3,4-oxadiazoles were synthesized by the cyclization of 2,6-pyridine dicarboxylic acid, 5-(4′-carboxyl-phenyl)-2-furanylcarboxylic acid, or p-phthalic acid, and aryl hydrazines in the presence of phosphorus oxychloride under the condition of microwave irradiation

Phosphorus, Sulfur and Silicon and the Related Elements published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C6H4ClNO2, COA of Formula: C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Xi-cun published the artcileSynthesis of 2-aryl-5-[5′-(4”-chlorophenyl)-2′-furyl]-1,3,4-oxadiazoles under microwave irradiation, Synthetic Route of 39115-95-2, the publication is Xibei Shifan Daxue Xuebao, Ziran Kexueban (2004), 40(4), 49-51, database is CAplus.

2-Aryl-5-[5′-(4”-chlorophenyl)-2′-furyl]-1,3,4-oxadiazoles is synthesized by cyclization of 5-(4′-chlorophenyl)-2-furancarboxylic acid and aroyl hydrazines in the presence of phosphorus oxychloride under the condition of microwave irradiation This synthetic strategy compared with traditional method has advantages of high yield, elevating reaction rate and simple work-up procedure.

Xibei Shifan Daxue Xuebao, Ziran Kexueban published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C3H5BN2O2, Synthetic Route of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Qu-xiang published the artcileSynthesis and characterization of acylthiosemicarbazides containing D-acetylglucosamine, Quality Control of 39115-95-2, the publication is Huaxue Shiji (2015), 37(2), 117-121, database is CAplus.

2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl isothiocyanat, e. g., I, was synthesized through following steps, acylation, chlorination and isothiocyanate with D-glucosamine hydrochloride as starting material. The reaction of 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl isothiocyanate with various hydrazides obtained 12 novel title compounds The structures were confirmed by IR, ¹HNMR and ESI-MS, and all glycosyl derivatives kept the original β-configuration.

Huaxue Shiji published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Quality Control of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kindt, Nadege published the artcilePharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells, HPLC of Formula: 41270-96-6, the publication is International Journal of Oncology (2013), 43(1), 185-193, database is CAplus and MEDLINE.

Recent clin. observations and exptl. studies of our group indicate that macrophage migration inhibitory factor (MIF) may contribute to tumor progression in head and neck squamous cell carcinomas (HNSCC). The present study was undertaken to examine the effects of the irreversible MIF inhibitor 4-iodo-6-phenylpyrimidine (4-IPP) on proliferation and invasiveness of the squamous carcinoma cell line SCCVII. Cell counting, crystal violet assay and flow cytometry were used to analyze the effects of 4-IPP on SCCVII cell growth. The impact of 4-IPP on cell invasiveness was assessed by Boyden chamber assay. Knockdown of the MIF receptor CD74 was achieved by transduction with lentiviral vectors encoding anti-CD74 shRNAs. As shown by immunofluorescence staining, SCCVII cells express both MIF and CD74. Decreased MIF immunoreactivity as a result of exposure to 4-IPP suggested a covalent modification of the cytokine. 4-IPP inhibited SCCVII cell proliferation and invasiveness. Moreover, the cytostatic effect of 4-IPP was enhanced by CD74 knockdown. The inhibitory effects of 4-IPP on cell proliferation and invasiveness strongly suggest that MIF is involved in proliferative activity and invasive properties of squamous carcinoma cells. In conclusion, MIF inhibition may open possibilities for target-directed treatment of head and neck squamous cell carcinoma.

International Journal of Oncology published new progress about 41270-96-6. 41270-96-6 belongs to iodides-buliding-blocks, auxiliary class Pyrimidine,Iodide,Benzene,Immunology/Inflammation,MIF, name is 4-Iodo-6-phenylpyrimidine, and the molecular formula is C10H7IN2, HPLC of Formula: 41270-96-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Budyka, Mikhail F. published the artcileProton-driven “one-way” photoisomerization due to energy transfer switching in styrylquinoline-merocyanine dyad, Related Products of iodides-buliding-blocks, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2014), 59-64, database is CAplus.

Photophys. and photochem. properties of the novel bichromophoric covalently linked dyad SQ3MC, where 2-styrylquinoline (SQ) and merocyanine (MC) chromophoric groups are connected by dioxytrimethylene bridge O-(CH₂)₃O, in comparison with model compounds 2-(4-methoxystyryl)quinoline MeSQ and 1-ethyl-2-(4-methoxystyryl)quinolinium perchlorate, which is O-methylated merocyanine MeMC, are investigated. In dyad SQ3MC, trans → cis photoisomerization of SQ moiety is quenched because of competing Forster resonance energy transfer (FRET) to MC fragment. However, reaction is switched on in protonated quasisym. dyad where pos. charged SQ fragment obtains the same chromophoric π-system as in MC chromophore. After deprotonation, photoisomerization of SQ fragment in trans → cis direction is again switched off but goes in cis → trans direction. Effect of “one-way” photoisomerization in the dyad SQ3MC is kinetic in nature and based on the difference in rates of competing processes in the excited state, in contrast to well-known one-way reactivity of diarylethylenes with large aryl substituents, where effect is thermodn. in nature and based on the difference in energies of the excited-state isomers and conformers.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Yuliang published the artcilePhotoinduced Cross-Coupling of Aryl Iodides with Alkenes, Formula: C7H4ClIO2, the publication is Organic Letters (2021), 23(2), 427-432, database is CAplus and MEDLINE.

A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes was developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent addition to alkenes was proposed. The method enabled iodide-selective cross-coupling over other halogen leaving groups with functional group compatibility on both arene and alkene motifs.

Organic Letters published new progress about 145343-76-6. 145343-76-6 belongs to iodides-buliding-blocks, auxiliary class Chloride,Iodide,Carboxylic acid,Benzene, name is 2-Chloro-4-iodobenzoic acid, and the molecular formula is C7H4ClIO2, Formula: C7H4ClIO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liang, Xinjie published the artcileCopper and L-(-)-quebrachitol catalyzed hydroxylation and amination of aryl halides under air, Name: 2-Chloro-4-iodobenzoic acid, the publication is Tetrahedron Letters (2020), 61(33), 152222, database is CAplus.

L-(-)-Quebrachitol, a natural product obtained from waste water of the rubber industry, was utilized as an efficient ligand for the copper-catalyzed hydroxylation and amination of aryl halides to selectively give phenols and aryl amines in water or 95% ethanol. In addition, the hydroxylation of 2-chloro-4-hydroxybenzoic acid was validated on a 100-g scale under air.

Tetrahedron Letters published new progress about 145343-76-6. 145343-76-6 belongs to iodides-buliding-blocks, auxiliary class Chloride,Iodide,Carboxylic acid,Benzene, name is 2-Chloro-4-iodobenzoic acid, and the molecular formula is C7H4ClIO2, Name: 2-Chloro-4-iodobenzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com