Tag: M.W=200-250

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Product Details of C5H4IN.

Andresini, Michael;Spennacchio, Mauro;Colella, Marco;Losito, Gianluca;Aramini, Andrea;Degennaro, Leonardo;Luisi, Renzo research published 《 Sulfinimidate Esters as an Electrophilic Sulfinimidoyl Motif Source: Synthesis of N-Protected Sulfilimines from Grignard Reagents》, the research content is summarized as follows. In this work the reactivity of sulfinimidate esters as an electrophilic sulfinimidoyl motif source was investigated, for the first time. The reaction of such sulfinimidate esters with Grignard reagents enables the preparation of protected sulfilimines I [R¹ = Ph, 4-ClC₆H₄, 3-MeOC₆H₄, etc.; R² = Me, i-Pr, Ph, etc.] in high yields and with a remarkable structural variability. Moreover, the transformation could be performed in CPME (cyclopentyl Me ether) as a green solvent under environmentally responsible conditions.

Product Details of C5H4IN, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Product Details of C6H6IN.

Ariawan, Daryl;Au, Carol;Paric, Esmeralda;Fath, Thomas;Ke, Yazi D.;Kassiou, Michael;van Eersel, Janet;Ittner, Lars M. research published 《 The nature of diamino linker and halogen bonding define selectivity of pyrrolopyrimidine-based LIMK1 Inhibitors》, the research content is summarized as follows. The LIM-domain kinase (LIMK) family consists of two isoforms, LIMK1 and LIMK2, which are highly homologous, making selective inhibitor development challenging. LIMK regulates dynamics of the actin cytoskeleton, thereby impacting many cellular functions including cell morphol. and motility. Here, we designed and synthesized analogs of a known pyrrolopyrimidine LIMK inhibitor with moderate selectivity for LIMK1 over LIMK2 to gain insights into which features contribute to both activity and selectivity. We incorporated a different stereochem. around a cyclohexyl central moiety to achieve better selectivity for different LIMK isoforms. Inhibitory activity was assessed by kinase assays, and biol. effects in cells were determined using an in vitro wound closure assay. Interestingly, a slight change in stereochem. alters LIMK isoform selectivity. Finally, a docking study was performed to predict how the new compounds interact with the target.

Product Details of C6H6IN, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., 626-01-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Recommanded Product: 3-Iodoaniline.

Asahara, Haruyasu;Mukaijo, Yusuke;Muragishi, Kengo;Iwai, Kento;Ito, Akitaka;Nishiwaki, Nagatoshi research published 《 Metal-Free and syn-Selective Hydrohalogenation of Alkynes through a Pseudo-Intramolecular Process》, the research content is summarized as follows. A new metal-free hydrohalogenation method for alkynes was developed, which proceeded through a pseudo-intramol. process. In this reaction, ethynylaniline served as a substrate to quant. form an anilinium salt upon treatment with hydrochloric acid. The spatial proximity facilitated the efficient electrophilic addition of HCl to the ethynyl group in syn-mode, affording the corresponding chloroalkene without overaddn. This protocol was applied to HBr and HI, and the corresponding bromo- and iodoalkenes were obtained, resp. The obtained chloroalkene was converted to tri-substituted alkenes possessing different aryl/alkynyl groups through Pd-catalyzed cross-coupling reactions.

626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., Recommanded Product: 3-Iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Recommanded Product: 3-Iodopyridine.

Averdunk, Arthur;Hasenbeck, Max;Mueller, Tizian;Becker, Jonathan;Gellrich, Urs research published 《 1,2-Carboboration of Arylallenes by In Situ Generated Alkenylboranes for the Synthesis of 1,4-Dienes》, the research content is summarized as follows. Authors herein report a novel method for the coupling of unactivated alkynes and arylallenes, which relies on an unprecedented and regioselective 1,2-carboboration of the allene by an alkenylborane. The alkenylborane is conveniently prepared in situ by hydroboration of an alkyne with Piers′ borane, i. e., HB(C₆F₅)₂. The boryl-substituted 1,4-dienes that are formed by this carboboration are well-suited for a subsequent Suzuki-Miyaura coupling with aryl iodides. This allowed authors′ to develop a three-step, one-pot protocol for the synthesis of aryl-substituted 1,4-dienes. The generality of the reaction was demonstrated by the synthesis of twenty dienes with modular variations of all three reaction partners. The mechanism of the new 1,2-carboboration was investigated using dispersion corrected double-hybrid DFT computations that allowed authors′ to rationalize the chemo- and regioselectivity of this key step.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Recommanded Product: 3-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine.The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. HPLC of Formula: 5029-67-4.

Awwadi, Firas F.;Alwahsh, Manal I.;Turnbull, Mark M.;Landee, Christopher P.;Twamley, Brendan research published 《 Two new canted antiferromagnetic systems: magnetic, theoretical, and crystallographic studies on trans-bis(2-iodopyridine)dihalocopper(II)》, the research content is summarized as follows. The two complexes Cu(2i.p.)X₂ were prepared (where 2i.p. = 2-iodopyridine and X = Cl or Br), and their crystal structures were determined The two complexes are isomorphous and form a magnetic chain based on the two-halide exchange pathway. The powder and single crystal magnetic susceptibility data were measured down to 1.8 K. The exchange is antiferromagnetic along the chain; the exchange is stronger in the bromide complex than in the corresponding chloride complex. In the ordered state, weak moments appear along some of the axes, indicative of spin-canting. The calculated spin densities and the mapped surface of spin d. on total electron d. were used to rationalize qual. the observed magnetic behavior. Low temperature structures are compared with the room temperature data; the C-I···X-Cu and Cu-X···X-Cu distances are shorter at low temperatures; in contrast, the covalent bonds of the organic ligand (2-iodopyridine) are longer (neg. thermal expansion of the covalent bonds). The anomalous behavior is rationalized using charge transfer from Cu-X group to the anti-bonding orbital of the organic ligand. Quantum theory of atoms in mols. was used to analyze C-I···X halogen bonding interactions.

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., HPLC of Formula: 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Quality Control of 1120-90-7.

Azizollahi, Hamid;Eshghi, Hossein;Garcia-Lopez, Jose-Antonio research published 《 Fe₃O₄-SAHPG-Pd⁰ nanoparticles: A ligand-free and low Pd loading quasiheterogeneous catalyst active for mild Suzuki-Miyaura coupling and C-H activation of pyrimidine cores》, the research content is summarized as follows. Green magnetic quasiheterogeneous efficient palladium catalyst in which Pd⁰ nanoparticles was immobilized in self-assembled hyperbranched polyglycidole (SAHPG)-coated magnetic Fe₃O₄ nanoparticles (Fe₃O₄-SAHPG-Pd⁰) was reported. This catalyst was used for effective ligandless Pd catalyzed Suzuki-Miyaura coupling reactions of different aryl halides with substituted boronic acids at room temperature and in aqueous media. SAHPG was used as support; it also acts as a reducing agent and stabilizer to promote the transformation of Pd^II to Pd⁰ nanoparticles. Also, this environmental friendly quasiheterogeneous catalyst was employed for the first time in the synthesis of new pyrimido[4,5-b]indoles via oxidative addition/C-H activation reactions on the pyrimidine rings, which were obtained with higher yield and faster than when Pd(OAc)₂ was used as the catalyst. Interestingly, the above-mentioned catalyst could be recovered in a facile manner from the reaction mixture by applying an external magnet device and recycled several times with no significant decrease in the catalytic activity.

Quality Control of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Recommanded Product: 2-Iodopyridine.

Azizollahi, Hamid;Eshghi, Hossein;Garcia-Lopez, Jose-Antonio research published 《 Fe₃O₄-SAHPG-Pd⁰ nanoparticles: A ligand-free and low Pd loading quasiheterogeneous catalyst active for mild Suzuki-Miyaura coupling and C-H activation of pyrimidine cores》, the research content is summarized as follows. Green magnetic quasiheterogeneous efficient palladium catalyst in which Pd⁰ nanoparticles was immobilized in self-assembled hyperbranched polyglycidole (SAHPG)-coated magnetic Fe₃O₄ nanoparticles (Fe₃O₄-SAHPG-Pd⁰) was reported. This catalyst was used for effective ligandless Pd catalyzed Suzuki-Miyaura coupling reactions of different aryl halides with substituted boronic acids at room temperature and in aqueous media. SAHPG was used as support; it also acts as a reducing agent and stabilizer to promote the transformation of Pd^II to Pd⁰ nanoparticles. Also, this environmental friendly quasiheterogeneous catalyst was employed for the first time in the synthesis of new pyrimido[4,5-b]indoles via oxidative addition/C-H activation reactions on the pyrimidine rings, which were obtained with higher yield and faster than when Pd(OAc)₂ was used as the catalyst. Interestingly, the above-mentioned catalyst could be recovered in a facile manner from the reaction mixture by applying an external magnet device and recycled several times with no significant decrease in the catalytic activity.

Recommanded Product: 2-Iodopyridine, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., 5029-67-4.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com