In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Quality Control of 5029-67-4.
Gao, Mingyang;Wang, Jiamin;Shang, Weixiang;Chai, Yuchao;Dai, Weili;Wu, Guangjun;Guan, Naijia;Li, Landong research published 《 Zeolite-encaged palladium catalysts for heterogeneous Suzuki-Miyaura cross-coupling reactions》, the research content is summarized as follows. Herein, zeolite-encaged Pd particles, namely Pd@MFI, have been successfully prepared via an in-situ hydrothermal strategy and investigated as promising heterogeneous catalysts for Suzuki-Miyaura cross-coupling reactions. Characterization results demonstrate that high dispersed Pd particles with apparent sizes of 1-2 nm have been encaged in and efficiently stabilized by the matrix of MFI zeolite. The as-prepared Pd@MFI catalysts are active in the Suzuki-Miyaura coupling reaction between bromobenzene and phenylboronic acid, and the presence of basic sites adjacent to Pd sites are crucial to achieving high catalytic activity via effective cooperation. Pd@K-ZSM-5 was optimized for the coupling between bromobenzene and phenylboronic acid and catalyze the reaction with a low apparent activation energy value of 41.2 kJ/mol. Pd@K-ZSM-5 also showed good stability and can be recycled for at least five times without obvious loss in activity, demonstrating its great potential as a heterogeneous catalyst for Suzuki-Miyaura cross-coupling reactions. Encapsulation of metal species in zeolite matrix offers a big opportunity to the heterogenization of homogeneous metal catalysts for practical chem. transformations.
5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Quality Control of 5029-67-4
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com