Tag: M.W=200-250

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Category: iodides-buliding-blocks.

Heusler, Arne;Fliege, Julian;Wagener, Tobias;Glorius, Frank research published 《 Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines》, the research content is summarized as follows. The synthesis of a broad variety of N-substituted 1,4-dihydropyridines I [R = H, 3-Me, 3,5-di-Br, etc.; R¹ = Tf, CO₂Ph] and 1,2-dihydropyridines II [R² = F, Cl, CF₃, Ph, SPh; R³ = H, F, trimethylsilyl] by very mild and selective reduction with amine borane was reported for the first time.

Category: iodides-buliding-blocks, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. COA of Formula: C6H6IN.

Himmelbauer, Daniel;Schratzberger, Heiko;Kaefer, Matthias G.;Stoeger, Berthold;Veiros, Luis F.;Kirchner, Karl research published 《 Nonsymmetrical Benzene-Pyridine-Based Nickel Pincer Complexes Featuring Borohydride, Formate, Ethyl, and Nitrosyl Ligands》, the research content is summarized as follows. Nonsym. Ni PCN pincer complexes [Ni(^iPrPCN^X)Cl] (X = NMe, CH₂) were obtained by metalation of the benzene-pyridine-based pincer ligand ^iPrPCN^X (X = NMe, CH₂) with [Ni(dme)Cl₂] (dme = 1,2-dimethoxyethane). These Ni species afforded the resp. borohydride and Et complexes [Ni(^iPrPCN^X)L] (L = BH₄, Et) upon treatment with NaBH₄ and EtMgBr (or Et₂Mg), resp. Reacting [Ni(^iPrPCN^X)(κ²-BH₄)] with CO₂ gave the formate complexes [Ni(^iPrPCN^X)(OCHO)]. Treatment of [Ni(^iPrPCN^X)Cl] with the nitrosyl salt NOBF₄ gave the unusual cationic square-pyramidal Ni nitrosyl pincer complexes [Ni(^iPrPCN^X)(NO)Cl]⁺ featuring a strongly bent NO ligand (∠Ni-N-O 128.5°). These systems can be described as {NiNO}¹⁰ according to the Enemark-Feltham convention. Despite of the bent nature of the NO ligand the ν_NO is observed at 1849 cm^-1 which is more typical for a linear Ni-N-O arrangement. The structure of these complexes is rationalized by DFT calculations The mol. structures of representative complexes are presented.

COA of Formula: C6H6IN, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., 626-01-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Related Products of 1120-90-7.

Horan, Alexandra M.;Duong, Vincent K.;McGarrigle, Eoghan M. research published 《 Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts》, the research content is summarized as follows. Herein ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts I (R = H, Br, Me, trifluoromethyl; R¹ = H, OMe, CN, Br, etc.; R² = H, trifluoromethyl; R³ = H, Me; R²R³ = -(CH=CH-CH=CH)-) and phenyl(pyrimidin-2-yl)(p-tolyl)sulfonium trifluoromethanesulfonate are reported. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages including 2,4′-bipyridines, 2,3′-bipyridines, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes II (R⁴ = 2-fluoropyridin-4-yl, pyrazin-2-yl, dimethyl-1,2-oxazol-4-yl, 1-benzothiophen-2-yl, etc.). The methodol. was successfully applied to the synthesis of the natural products caerulomycin A and E.

Related Products of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. HPLC of Formula: 5029-67-4.

Horan, Alexandra M.;Duong, Vincent K.;McGarrigle, Eoghan M. research published 《 Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts》, the research content is summarized as follows. Herein ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts I (R = H, Br, Me, trifluoromethyl; R¹ = H, OMe, CN, Br, etc.; R² = H, trifluoromethyl; R³ = H, Me; R²R³ = -(CH=CH-CH=CH)-) and phenyl(pyrimidin-2-yl)(p-tolyl)sulfonium trifluoromethanesulfonate are reported. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages including 2,4′-bipyridines, 2,3′-bipyridines, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes II (R⁴ = 2-fluoropyridin-4-yl, pyrazin-2-yl, dimethyl-1,2-oxazol-4-yl, 1-benzothiophen-2-yl, etc.). The methodol. was successfully applied to the synthesis of the natural products caerulomycin A and E.

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., HPLC of Formula: 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Computed Properties of 1120-90-7.

Hosseini-Sarvari, Mona;Akrami, Zahra research published 《 Nano Ni/g-C₃N₄ Photocatalyzed Aerobic Oxidative Coupling Reaction toward Alkyl Aryl Ketones Derivatives under Visible Light Irradiation》, the research content is summarized as follows. In the present study, the synthesis of a group of carbonyl compounds that are widely used in the chem. and pharmaceutical industries was prepared under mild and safe conditions. Authors developed a new method based on the nickel/carbon nitride (Ni/g-C₃N₄) dual photocatalytic system to synthesize ketones without using expensive oxidants and heating. This article describes the oxidative coupling reactions between tertiary amines and aryl halides resulting in the production of natural aryl alkyl ketones. It should be noted that all these reactions were carried out using visible light, green solvents under eco-friendly, one-pot conditions, an air atm., at room temperature, without the use of any oxidant.

Computed Properties of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Related Products of 1120-90-7.

Hsiao, Pu-Yen;Chang, Rong;Sue, Andrew C.-H.;Chu, Jean-Ho;Liao, Guan-Wei;Lee, Yi-Hsin;Huang, Jui-Yang research published 《 Synthesis and Mechanistic Investigation of Bipyrazolo[1,5-a]pyridines via Palladium-Catalyzed Cross-Dehydrogenative Coupling of Pyrazolo[1,5-a]pyridines》, the research content is summarized as follows. The synthesis of a range of 3,3′-bipyrazolo[1,5-a]pyridine derivatives via direct cross-dehydrogenative coupling of pyrazolo[1,5-a]pyridine precursors was herein presented. This simple and efficient methodol. involving palladium(II)-catalyzed C-H bond activation showed good functional group tolerance and product yield (up to 94%). Through the mechanistic insights gained from both kinetic isotope effect exptl. studies and d. functional theory calculations, a plausible reaction mechanism was outlined. Furthermore, subsequent derivatizations of the resulting 7,7′-diaryl-3,3′-bipyrazolo[1,5-a]pyridines, executed by performing palladium-mediated ortho C-H bond activation followed by hypervalent iodine-induced chlorination, rendered this series of compounds more extended π-conjugation and twisted conformations. The study on these bipyrazolo[1,5-a]pyridine-based luminogens provided new opportunities for tailor-made organic luminescent materials.

Related Products of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Recommanded Product: 2-Iodopyridine.

Gabbey, Alexis L.;Michel, Nicholas W. M.;Hughes, Jonathan M. E.;Campeau, Louis-Charles;Rousseaux, Sophie A. L. research published 《 Synthesis of α-Aryl Secondary Amides via Nickel-Catalyzed Reductive Coupling of Redox-Active Esters》, the research content is summarized as follows. A strategy to synthesize secondary α-aryl amides via a Ni-catalyzed reductive arylation of redox-active N-hydroxyphthalimide (NHP) esters of malonic acid half amides was reported. This transformation proceeded under mild conditions and displays excellent chemoselectivity for amide α-arylation in the presence of other enolizable carbonyls. The NHP ester substrates were readily prepared from Meldrum’s acid.

Recommanded Product: 2-Iodopyridine, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., 5029-67-4.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Name: 3-Iodoaniline.

Gabbey, Alexis L.;Michel, Nicholas W. M.;Hughes, Jonathan M. E.;Campeau, Louis-Charles;Rousseaux, Sophie A. L. research published 《 Synthesis of α-Aryl Secondary Amides via Nickel-Catalyzed Reductive Coupling of Redox-Active Esters》, the research content is summarized as follows. A strategy to synthesize secondary α-aryl amides via a Ni-catalyzed reductive arylation of redox-active N-hydroxyphthalimide (NHP) esters of malonic acid half amides was reported. This transformation proceeded under mild conditions and displays excellent chemoselectivity for amide α-arylation in the presence of other enolizable carbonyls. The NHP ester substrates were readily prepared from Meldrum’s acid.

Name: 3-Iodoaniline, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., 626-01-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. COA of Formula: C6H6IN.

Gagne-Boulet, Mathieu;Bouzriba, Chahrazed;Chavez Alvarez, Atziri Corin;Fortin, Sebastien research published 《 Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site》, the research content is summarized as follows. Herein, 15 new Ph 4-(2-oxopyrrolidin-1-yl)benzenesulfonate (PYB-SO) and 15 Ph 4-(2-oxopyrrolidin-1-yl)benzenesulfonamide (PYB-SA) derivatives, I [X = O, NH; R = H, 2-iso-Pr, 4-Ph, etc.] were designed, prepared, chem. characterized, biol. evaluated and the effect of pyrrolidin-2-one moiety was also evaluated. Compounds I exhibited antiproliferative activity in the low nanomolar to low micromolar range (0.0087-8.6μM and 0.056-21μM, resp.) on human HT-1080, HT-29, M21 and MCF7 cancer cell lines. Moreover, they block cell cycle progression in G2/M phase. Immunofluorescence, tubulin affinity and tubulin polymerization assays showed that they cause microtubule depolymerization by docking the C-BS. In addition, docking assays with the most potent derivatives showed binding affinity toward the C-BS and they also exhibited weak or no toxicity toward chick embryos. Finally, physicochem. properties calculated using the SwissADME algorithm showed that PYB-SOs and PYB-SAs I were promising new families of antimicrotubule agents.

626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., COA of Formula: C6H6IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Product Details of C5H4IN.

Gajanan;Rathod, K.;Jain, Rahul research published 《 Palladium-Catalyzed Aminocarbonylation of Heteroaryl Iodides》, the research content is summarized as follows. Palladium-catalyzed aminocarbonylation of heteroaryl iodides was reported in the presence of chloroform as the carbon monoxide surrogate. The substrate scope of the reaction was demonstrated by the synthesis of quinoline-3-carboxamides and other heteroaryl amides in yields up to 90% under non-inert conditions and microwave irradiation at 80°C in 30 min. This carbonylation method provided efficient access to previously inaccessible biol. important heteroaryl carboxamides.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Product Details of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com