Tag: 500-600

Organocatalytic Synthesis of Phenols from Diaryliodonium Salts with Water under Metal-Free Conditions was written by Katagiri, Kotone;Kuriyama, Masami;Yamamoto, Kosuke;Demizu, Yosuke;Onomura, Osamu. And the article was included in Organic Letters in 2022.Application of 139139-80-3 The following contents are mentioned in the article:

The metal-free synthesis of phenols ArOH [Ar = 4-MeC₆H₄, 3-MeC₆H₄, 4-ClC₆H₄, etc.] from diaryliodonium salts with water was developed by using N-benzylpyridin-2-one as an organocatalyst. In this process, sterically congested, functionalized, and heterocycle-containing iodonium salts were smoothly converted to the desired products, and the clofibrate and mecloqualone derivatives were also synthesized in high yields. In addition, the gram-scale experiment was successfully carried out with 10 mmol of a sterically congested substrate. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Application of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Application of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

One-Pot C-H Functionalization of Arenes by Diaryliodonium Salts was written by Reitti, Marcus;Villo, Piret;Olofsson, Berit. And the article was included in Angewandte Chemie, International Edition in 2016.Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate The following contents are mentioned in the article:

A transition metal-free, mild, and highly regioselective synthesis of nitroarenes from arenes has been developed. The products are obtained in a sequential one-pot reaction by nitration of iodine(III) reagents with two carbon ligands, which are formed in situ from iodine(I). This novel concept has been extended to formation of aryl azides, and constitutes an important step towards catalytic reactions with these hypervalent iodine reagents. An efficient nitration of isolated diaryliodonium salts has also been developed, and the mechanism is proposed to proceed by a [2,2] ligand coupling pathway. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Safety of Bis(2,4,6-trimethylphenyl)iodonium triflate

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

New and direct approach to hypervalent iodine compounds from arenes and iodine. Straightforward synthesis of (diacetoxyiodo)arenes and diaryliodonium salts using potassium μ-peroxo-hexaoxodisulfate was written by Hossain, Delwar Md.;Kitamura, Tsugio. And the article was included in Bulletin of the Chemical Society of Japan in 2007.Recommanded Product: 139139-80-3 The following contents are mentioned in the article:

The reaction of arenes with elemental iodine, acetic acid, and potassium μ-peroxo-hexaoxodisulfate (K₂S₂O₈) in the presence of concentrated sulfuric acid, efficiently generated the corresponding (diacetoxyiodo)arenes in good yields. Diaryliodonium triflates were directly synthesized by reaction of arenes with elemental iodine in good yields by using K₂S₂O₈, AcOH, and TfOH. Diaryliodonium tosylates were also prepared from arenes and elemental iodine by using K₂S₂O₈, AcOH, H₂SO₄, and TsOH. The procedure involved mild conditions and a straightforward one-pot synthesis. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Recommanded Product: 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Recommanded Product: 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A Three-component Cascade Cyclization to Construct 3-(2-Oxopropyl)-2-arylisoindolinone Derivatives via Copper-catalyzed Annulation was written by Liu, Li;Bai, Shu-Hua;Li, Yang;Ding, Xiao-Dan;Liu, Qian;Li, Jian. And the article was included in Advanced Synthesis & Catalysis in 2018.Formula: C19H22F3IO3S The following contents are mentioned in the article:

In the presence of Cu(OTf)₂, o-formylbenzonitriles, ketones such as acetophenone, and diaryliodonium triflates such as (4-BrC₆H₄)₂I⁺OTf^– underwent cascade arylation, cyclization and addition reactions in 1,2-dichloroethane to yield (oxoalkyl)arylisoindolinones such as I in 51-90% yields; α-methylstyrene and di-Et malonate were also used instead of ketones to yield a propenylisoindolinone and an aryloxoisoindolylmalonate, resp. Copper-catalyzed arylation, cyclization and addition followed by ketone reduction and Friedel-Crafts reactions yielded isoindoloquinolinones such as II. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Oxidative Cyclization of 4-(2-Mercaptophenyl)-Substituted 4H-1,2,4-Triazolium Species to Tricyclic Benzothiazolium Salts was written by Ardon-Munoz, Luis G.;Bolliger, Jeanne L.. And the article was included in European Journal of Organic Chemistry in 2022.Electric Literature of C19H22F3IO3S The following contents are mentioned in the article:

Herein authors report a generally applicable method for the preparation of N-substituted benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-1-ium salts from air stable precursors. This transformation features selective deprotection of a para-methoxybenzyl protected thiol followed by C-H functionalization of the linked 1,2,4-triazolium salts under oxidative conditions. Using this procedure, authors synthesized a variety of tricyclic thiazolium salts which contain both electron-withdrawing and electron-donating aromatic substituents as well as aliphatic substituents. Authors approach also tolerates many functional groups including alkynes, alcs., diols, amides, and polyethers. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Electric Literature of C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Electric Literature of C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Selective Synthesis of ortho-Substituted Diarylsulfones by Using NHC-Au Catalysts under Mild Conditions was written by Zhu, Haibo;Shen, Yajing;Wen, Daheng;Le, Zhang-Gao;Tu, Tao. And the article was included in Organic Letters in 2019.Computed Properties of C19H22F3IO3S The following contents are mentioned in the article:

A single-step gold(I)-catalyzed chemoselective protocol to access ortho-substituted diarylsulfones has been established. Acenaphthoimidazolylidene gold complexes are effective catalysts for the arylsulfonylation of boronic acids by potassium metabisulfite (K₂S₂O₅) and diaryliodonium salts to access (poly-)ortho-substituted diarylsulfones even in gram scale. Unlike the transition metal-catalyzed two-component coupling systems, the sterically hindered aryl groups in diaryliodonium salts are preferentially transferred over less bulky ones to form synthetically difficult targets, including those of pharmaceutical importance. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Computed Properties of C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-Catalyzed Tandem Amide N-Arylation and Regioselective Cyclization of 2-Alkynylbenzamides was written by Minami, Hideki;Sueda, Takuya;Okamoto, Noriko;Miwa, Yoshihisa;Ishikura, Minoru;Yanada, Reiko. And the article was included in European Journal of Organic Chemistry in 2016.Reference of 139139-80-3 The following contents are mentioned in the article:

A new approach to form iminoisocoumarins from readily available and stable 2-alkynylbenzamides was developed by using a tandem copper-catalyzed N-arylation and regioselective 6-endo-dig cyclization in the presence of diaryliodonium salts, a copper catalyst and 2,6-bis(tert-butyl)pyridine. The arylation occurred at the nitrogen atom rather than the oxygen atom of the amide group, the alkynyl carbon, or the benzene ring of the benzamide. Cyclization occurred through a preferential nucleophilic attack by the oxygen rather than the nitrogen atom of the amide group to produce iminoisocoumarin derivatives in good to moderate yields. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Reference of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Reference of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Combining Transition Metal Catalysis with Radical Chemistry: Dramatic Acceleration of Palladium-Catalyzed C-H Arylation with Diaryliodonium Salts was written by Neufeldt, Sharon R.;Sanford, Melanie S.. And the article was included in Advanced Synthesis & Catalysis in 2012.Reference of 139139-80-3 The following contents are mentioned in the article:

This paper describes a photoredox palladium/iridium-catalyzed C-H arylation with diaryliodonium reagents. Details of the reaction optimization, substrate scope, and mechanism are presented along with a comparison to a related method in which aryldiazonium salts are used in place of diaryliodonium reagents. The unprecedentedly mild reaction conditions (25 °C in methanol), the requirement for light and a photocatalyst, the inhibitory effect of radical scavengers, and the observed chemoselectivity trends are all consistent with a radical-mediated mechanism for this transformation. This stands in contrast to the analogous thermal reaction with diaryliodonium reagents that is believed to proceed via an ionic’ 2e^– pathway and requires a much higher reaction temperature (100 °C). This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Reference of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Reference of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Efficient O-Functionalization of Carbohydrates with Electrophilic Reagents was written by Tolnai, Gergely L.;Nilsson, Ulf J.;Olofsson, Berit. And the article was included in Angewandte Chemie, International Edition in 2016.COA of Formula: C19H22F3IO3S The following contents are mentioned in the article:

Novel methodol. for O-functionalization of carbohydrate derivatives has been established using bench-stable and easily prepared iodonium(III) reagents. Both electron-withdrawing and electron-donating aryl groups were introduced under ambient conditions and without precautions to exclude air or moisture. Furthermore, the approach was extended both to full arylation of cyclodextrin, and to trifluoroethylation of carbohydrate derivatives This is the first general approach to introduce traditionally non-electrophilic groups into any of the OH groups around the sugar backbone. The methodol. will be useful both in synthetic organic chem. and biochem., as important functional groups can be incorporated under simple and robust reaction conditions in a fast and efficient manner. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3COA of Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.COA of Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis of Aryl Sulfides by Metal-Free Arylation of Thiols with Diaryliodonium Salts under Basic Conditions was written by Sarkar, Sudeep;Wojciechowska, Natalia;Rajkiewicz, Adam A.;Kalek, Marcin. And the article was included in European Journal of Organic Chemistry in 2022.HPLC of Formula: 139139-80-3 The following contents are mentioned in the article:

Metal-free arylation of thiols RSH (R = n-Bu, Bn, 2,3-dihydro-1,3-benzothiazol-2-yl, etc.) with diaryliodonium salts (Ar)₂I⁺TfO^–(Ar = 2,4,6-trimethylphenyl, 2-fluorophenyl, 4-nitrophenyl, etc.) have been developed. The application of a strong organic base enables the C-S bond formation under mild and exptl. simple conditions. The method allows for the synthesis of aryl sulfides R¹SAr containing a broad range of aryl groups from an array of thiols, including aryl, heteroaryl, and alkyl ones. The mechanism of the reaction was studied by DFT calculations, demonstrating that it proceeds via the inner sphere pathway involving formation of an Ar₂I(SR) intermediate, followed by reductive elimination. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3HPLC of Formula: 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). HPLC of Formula: 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com