Tag: 500-600

Pd/NHC-catalyzed arylsulfonylation of boronic acids: A general and direct protocol to access diarylsulfones was written by Zhu, Haibo;Yang, Liu;Meng, Jia;Xie, Zongbo;Le, Zhang-Gao;Tu, Tao. And the article was included in Tetrahedron Letters in 2021.Formula: C19H22F3IO3S The following contents are mentioned in the article:

For the first time, robust NHC-Pd complexes have been demonstrated as highly efficient catalysts in the direct arylsulfonylation of boronic acids. Remarkably, a broad number of diaryliodonium salts as powerful electrophilic arylation reagents are well compatible to form functional ortho-substituted diarylsulfones, e.g., I in satisfactory yields. Owing to the stronger σ-donor and weaker π-acceptor properties, the acenaphthoimidazolylidene ligands exhibit higher catalytic activities towards this challenging one-step arylsulfonylation reaction. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Transition metal-free N-arylation of amino acid esters with diaryliodonium salts was written by Kervefors, Gabriella;Kersting, Leonard;Olofsson, Berit. And the article was included in Chemistry – A European Journal in 2021.Computed Properties of C19H22F3IO3S The following contents are mentioned in the article:

A transition metal-free approach for the N-arylation of amino acid derivatives has been developed. Key to this method is the use of unsym. diaryliodonium salts with anisyl ligands, which proved important to obtain high chemoselectivity and yields. The scope includes the transfer of both electron deficient, electron rich and sterically hindered aryl groups with a variety of different functional groups. Furthermore, a cyclic diaryliodonium salt was successfully employed in the arylation. The N-arylated products were obtained with retained enantiomeric excess. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Computed Properties of C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Computed Properties of C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Versatile and base-free copper-catalyzed α-arylations of aromatic ketones using diaryliodonium salts was written by Bouquin, Maxime;Jaroschik, Florian;Taillefer, Marc. And the article was included in Tetrahedron Letters in 2021.Computed Properties of C19H22F3IO3S The following contents are mentioned in the article:

A ligand and base-free copper catalyzed synthetic method for the efficient α-arylation of aromatic ketones ArC(O)CH₂Ar¹ [Ar = Ph, 4-BrC₆H₄, 2-thienyl, etc.; Ar¹ = Ph, 2-MeC₆H₄, 4-FC₆H₄, etc.] was described. In order to avoid strong bases, ketone-derived silyl enol ethers were employed. Their reaction with diaryliodonium salts as aryl source provided the intermol. C-C coupling displaying good functional group tolerance and requiring low catalyst loading. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Computed Properties of C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Computed Properties of C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Catalyst-Free Arylation of Tertiary Phosphines with Diaryliodonium Salts Enabled by Visible Light was written by Bugaenko, Dmitry I.;Volkov, Alexey A.;Livantsov, Mikhail V.;Yurovskaya, Marina A.;Karchava, Alexander V.. And the article was included in Chemistry – A European Journal in 2019.Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate The following contents are mentioned in the article:

The visible-light-induced arylation of tertiary phosphines with aryl(mesityl)iodonium triflates to produce the quaternary phosphonium salts occurs under mild, metal, and catalyst-free conditions. Photoexcited EDA complexes between diaryliodonium salts and phosphines supposedly enable this transformation, which is difficult to achieve through the traditional ground-state reactions. Demonstrating high functional group tolerance, broad scope, and complete selectivity of the aryl group transfer, the method is particularly compatible with sterically congested phosphines, which are challenging under metal-based catalytic methods. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-catalyzed N-arylation of tert-butyl N-sulfonylcarbamates with diaryliodonium salts at room temperature was written by Moon, Soo-Yeon;Koh, Moonjee;Rathwell, Kris;Jung, Seo-Hee;Kim, Won-Suk. And the article was included in Tetrahedron in 2015.HPLC of Formula: 139139-80-3 The following contents are mentioned in the article:

A new and mild synthetic approach for the synthesis of N-arylsulfonamides I [R¹ = H, 4-Me, 4-F, etc; R = Me, ph, 4-Me-C₆H₄, etc] under copper-catalyzed conditions at room temperature has been developed. The reaction employs various tert-Bu N-sulfonylcarbamates and diaryliodonium salts to avoid potential genotoxic impurities. A one-pot coupling/Boc-deprotection sequence is also reported to provide mono N-arylsulfonamides II [R¹ =H, 4-F, etc; R =4-Me-C₆H₄, 4-OMe-C₆H₄, etc] in good to excellent yields. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3HPLC of Formula: 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.HPLC of Formula: 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Transition metal-free, chemoselective arylation of thioamides yielding aryl thioimidates or N-aryl thioamides was written by Villo, Piret;Kervefors, Gabriella;Olofsson, Berit. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Reference of 139139-80-3 The following contents are mentioned in the article:

A transition metal-free efficient method was developed for the synthesis of aryl thioimidates I [R = n-hexyl, Boc, Bn; R¹ = i-Pr, c-hexyl, Ph, etc.; Ar = Ph, 4-MeC₆H₄, 3-pyridyl, etc.] in good to excellent yields via chemoselective S-arylation of thioamides with diaryliodonium salts under basic conditions. Reactions with thiolactams delivered N-aryl thioamides, e.g., II in good yields at room temperature Equimolar amounts of thioamide, base and diaryliodonium salt were sufficient to obtain a diverse selection of products within short reaction times. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Reference of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Reference of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metal-free regioselective formation of C-N and C-O bonds with the utilization of diaryliodonium salts in water: facile synthesis of N-arylquinolones and aryloxyquinolines was written by Mehra, Manish Kumar;Tantak, Mukund P.;Arun, V.;Kumar, Indresh;Kumar, Dalip. And the article was included in Organic & Biomolecular Chemistry in 2017.Product Details of 139139-80-3 The following contents are mentioned in the article:

Regioselective construction of crucial C-N and C-O bonds leading to N-arylquinolones and aryloxyquinolines was accomplished by employing easily accessible diaryliodonium salts and quinolones in water under metal- and ligand-free conditions. This operationally simple strategy was significant due to mild reaction conditions, high product yields, recyclability of released iodoarenes and scalability to the gram level. The practical utility of the developed protocol was proved by the arylation of medicinally important heterocycles like acridin-9(10H)-one, 3-methylquinoxalin-2(1H)-one and 1H-benzo[d]imidazol-2(3H)-one. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Product Details of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Product Details of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper(I) Bromide Catalyzed Arylation of Cyclic Enamides and Naphthyl-1-acetamides Using Diaryliodonium Salts was written by Prakash, Muthuraj;Muthusamy, Subramaniam;Kesavan, Venkitasamy. And the article was included in Journal of Organic Chemistry in 2014.Related Products of 139139-80-3 The following contents are mentioned in the article:

Copper(I) bromide catalyzed direct C-H arylation of cyclic enamides was achieved using diaryliodonium salts in the absence of base/additive at ambient temperature with high yields. E.g., in presence of CuBr in CH₂Cl₂ at 25 °C, arylation of cyclic enamide (I) with diaryliodonium triflate (II) gave 82% III. A biol. active dihydrobenzo[a]carbazole scaffold was synthesized using the established protocol. The scope of the current methodol. was further extended for the synthesis of C4-, C7-aryl-substituted 1-naphthylacetamides in good yields. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Related Products of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Related Products of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Catalyst-Free Visible Light Mediated Synthesis of Unsymmetrical Tertiary Arylphosphines was written by Bugaenko, Dmitry I.;Karchava, Alexander V.. And the article was included in Advanced Synthesis & Catalysis in 2022.Formula: C19H22F3IO3S The following contents are mentioned in the article:

Arylation of tertiary aryl and alkyl phosphines bearing 2-cyanoethyl group with aryl(mesityl)iodonium triflates under blue light irradiation followed by retro-Michael reaction of the in situ generated quaternary phosphonium salts initiated by DBU represent a novel efficient and general method for the preparation of distinctly substituted tertiary arylphosphines. An operationally simple, one-pot protocol features mild, transition-metal-free conditions, high selectivity, broad functional group compatibility, as well as scalability and would be applied to substrates with different electronic and steric nature. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Visible Light Accelerated Vinyl C-H Arylation in Pd-Catalysis: Application in the Synthesis of ortho Tetra-substituted Vinylarene Atropisomers was written by Feng, Jia;Li, Bin;Jiang, Julong;Zhang, Mingkai;Ouyang, Wenbai;Li, Chunyu;Fu, Yao;Gu, Zhenhua. And the article was included in Chinese Journal of Chemistry in 2018.Quality Control of Bis(2,4,6-trimethylphenyl)iodonium triflate The following contents are mentioned in the article:

A visible light accelerated C-H functionalization reaction in Pd-catalyzed arylation of vinyl arenes with diaryliodonium salts is reported in the absence of addnl. photosensitizer. The kinetic isotope effect (k_H/k_D) was changed from 3.6 (under darkness) to 1.1 when irradiated by visible light, which indicated that the C-H functionalization step was the rate determining step under darkness and significantly accelerated by the irradiation of visible light. Finally the synthesis of ortho tetra-substituted vinylarene atropisomers with high enantiospecificity was realized via this protocol. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Quality Control of Bis(2,4,6-trimethylphenyl)iodonium triflate).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Quality Control of Bis(2,4,6-trimethylphenyl)iodonium triflate

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com