Tag: 500-600

Copper-Catalyzed Selective N-Arylation of Oxadiazolones by Diaryliodonium Salts was written by Soldatova, Natalia S.;Semenov, Artem V.;Geyl, Kirill K.;Baykov, Sergey V.;Shetnev, Anton A.;Konstantinova, Anna S.;Korsakov, Mikhail M.;Yusubov, Mekhman S.;Postnikov, Pavel S.. And the article was included in Advanced Synthesis & Catalysis in 2021.Formula: C19H22F3IO3S The following contents are mentioned in the article:

The method for copper-catalyzed N-arylation of diverse oxadiazolones I (R¹ = cyclopropyl, Ph, 5-methylthiophen-2-yl, etc.) by diaryliodonium salts R²I⁺(R³)R^4- (R² = Ph, 3-(trifluoromethyl)phenyl, 4-nitrophenyl, etc.; R³ = Ph, 2,4,6-trimethoxyphenyl, 4-bromophenyl, etc.) under mild conditions in high yields (up to 92%) using available CuI as a catalyst was reported. The developed method allows utilizing both sym. and unsym. diaryliodonium salts bearing auxiliary groups such as 2,4,6-trimethoxyphenyl (TMP). The steric effects in aryl moieties determined the chemoselectivity of N- and O-arylation of the 1,2,4-oxadiazol-5(4H)-ones I. Mesityl-substituted diaryliodonium salts demonstrated the high potential as a selective arylation reagent. The structural study suggests that steric accessibility of N-atom in 1,2,4-oxadiazol-5(4H)-ones I impacts the arylation with sterically hindered diaryliodonium salts. The synthetic application of proposed method was also demonstrated on selective arylation of 1,3,4-oxadiazol-2(3H)-ones II and 3-(p-Tolyl)-1,2,4-oxadiazole-5-thiol. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Catalyst- and Additive-Free Trifluoromethylselenolation with [Me₄N][SeCF₃] was written by Dong, Tao;He, Jian;Li, Zhi-Han;Zhang, Cheng-Pan. And the article was included in ACS Sustainable Chemistry & Engineering in 2018.Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate The following contents are mentioned in the article:

Environment-benign trifluoromethylselenolation of alkyl halides, electron-deficient aryl halides, diaryliodonium triflates, aryldiazonium tetrafluoroborates, and α-diazo carbonyls with the readily accessible [Me₄N][SeCF₃] salt is described. A large number of structurally diversified substrates, previously trifluoromethylselenolated by metal-SeCF₃ complex or under metal-mediated catalysis at elevated temperatures, were smoothly converted in this reaction at room temperature or -40 °C to room temperature without using any catalyst or additive. Yields of the reactions were comparative to or even higher than those of the early reports employing transition metal catalysts. Compared to the known means, advantages of this method include simplicity, sustainability, high speed, low reaction temperatures, mild reaction conditions, a wide range of substrates, and good functional group tolerance. This catalyst- and additive-free protocol allows a mild and straightforward synthesis of various trifluoromethyl selenoethers and demonstrates the possibility of trifluoromethylselenolation with [Me₄N][SeCF₃] under greener conditions. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Recommanded Product: Bis(2,4,6-trimethylphenyl)iodonium triflate

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reengineering Chemical Glycosylation: Direct, Metal-Free Anomeric O-Arylation of Unactivated Carbohydrates was written by Lucchetti, Nicola;Gilmour, Ryan. And the article was included in Chemistry – A European Journal in 2018.Application of 139139-80-3 The following contents are mentioned in the article:

To sustain innovation in glycobiol., effective routes to well-defined carbohydrate probes must be developed. For over a century, glycosylation has been dominated by the formation of the anomeric Csp³-O acetal junction in glycostructures. A dissociative mechanistic spectrum spanning S_N1 and S_N2 is frequently operational thereby reducing the efficiency. By reengineering this fundamental process, an orthogonal disconnection allows the acetal to be formed directly from the reducing sugar without the need for substrate pre-functionalization. The use of stable aryliodonium salts facilitates a formal O-H functionalization reaction. This allows lactols to undergo mild, metal-free O-arylation at ambient temperature The efficiency of the transformation has been validated using a variety of pyranoside and furanoside monosaccharides in addition to biol. relevant di- and trisaccharides (up to 85 %). Fluorinated mechanistic probes that augment the anomeric effect were employed. It is envisaged that this strategy will prove expansive for the construction of complex acetals under substrate-based stereocontrol. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Application of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Application of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com