Tag: 500-600

Copper-Catalyzed Selective N-Arylation of Oxadiazolones by Diaryliodonium Salts was written by Soldatova, Natalia S.;Semenov, Artem V.;Geyl, Kirill K.;Baykov, Sergey V.;Shetnev, Anton A.;Konstantinova, Anna S.;Korsakov, Mikhail M.;Yusubov, Mekhman S.;Postnikov, Pavel S.. And the article was included in Advanced Synthesis & Catalysis in 2021.Formula: C19H22F3IO3S The following contents are mentioned in the article:

The method for copper-catalyzed N-arylation of diverse oxadiazolones I (R¹ = cyclopropyl, Ph, 5-methylthiophen-2-yl, etc.) by diaryliodonium salts R²I⁺(R³)R^4- (R² = Ph, 3-(trifluoromethyl)phenyl, 4-nitrophenyl, etc.; R³ = Ph, 2,4,6-trimethoxyphenyl, 4-bromophenyl, etc.) under mild conditions in high yields (up to 92%) using available CuI as a catalyst was reported. The developed method allows utilizing both sym. and unsym. diaryliodonium salts bearing auxiliary groups such as 2,4,6-trimethoxyphenyl (TMP). The steric effects in aryl moieties determined the chemoselectivity of N- and O-arylation of the 1,2,4-oxadiazol-5(4H)-ones I. Mesityl-substituted diaryliodonium salts demonstrated the high potential as a selective arylation reagent. The structural study suggests that steric accessibility of N-atom in 1,2,4-oxadiazol-5(4H)-ones I impacts the arylation with sterically hindered diaryliodonium salts. The synthetic application of proposed method was also demonstrated on selective arylation of 1,3,4-oxadiazol-2(3H)-ones II and 3-(p-Tolyl)-1,2,4-oxadiazole-5-thiol. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water was written by Geng, Xu;Mao, Song;Chen, Liangshun;Yu, Jianjun;Han, Jianwei;Hua, Jianli;Wang, Limin. And the article was included in Tetrahedron Letters in 2014.Formula: C19H22F3IO3S The following contents are mentioned in the article:

An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis of functionalized unsymmetrical diaryliodonium salts was written by Shah, Aneela;Pike, Victor W.;Widdowson, David A.. And the article was included in Journal of the Chemical Society in 1997.Category: iodides-buliding-blocks The following contents are mentioned in the article:

A generalized synthesis of unsym. functionalized diaryliodonium salts has been developed through the direct reaction of bis(acetoxy)iodoarene derivatives with arenes in a trifluoromethanesulfonic or trifluoroacetic acid medium. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Category: iodides-buliding-blocks).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Product subclass 1: hypervalent iodoarenes and aryliodonium salts was written by Zhdankin, V. V.. And the article was included in Science of Synthesis in 2007.Related Products of 139139-80-3 The following contents are mentioned in the article:

A review of methods to prepare hypervalent iodoarenes and aryliodonium salts and their applications to organic synthesis. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Related Products of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Related Products of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Transition-metal-free 伪-arylation of nitroketones with diaryliodonium salts for the synthesis of tertiary 伪-aryl, 伪-nitro ketones was written by An, Yang;Zhang, Xiao-Ming;Li, Ze-Yu;Xiong, Wen-Hui;Yu, Run-Dong;Zhang, Fu-Min. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Application of 139139-80-3 The following contents are mentioned in the article:

Transition-metal-free 伪-arylation of 伪-nitroketones with diaryliodonium salts was realized for the first time. As an application of this methodol., a concise synthesis of the clin. drug tiletamine was also achieved via a three-step procedure from 2-nitrocyclohexanone without the isolation of intermediates. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Application of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Application of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

P(NMe₂)₃-promoted ortho-selective arylation of phenols with diaryliodonium triflates via rhodium catalysis was written by Liu, Qi-Sheng;Wang, De-Yin;Yang, Jin-Fei;Ma, Zhong-Yi;Ye, Mengchun. And the article was included in Tetrahedron in 2017.Formula: C19H22F3IO3S The following contents are mentioned in the article:

Rh-catalyzed ortho-selective arylation of free phenol with diaryliodonium triflates to widely existed phenol-containing biaryls have been developed. The use of P(NMe₂)₃, ^tBuOLi and CH₃CN proved to be critical for the ortho-selectivity of this reaction. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodosyl trifluoromethanesulfonate – an efficient reagent for the single-step preparation of diaryliodonium triflate salts was written by Stang, Peter J.;Zhdankin, Viktor V.;Tykwinski, Rik;Zefirov, N. S.. And the article was included in Tetrahedron Letters in 1991.Electric Literature of C19H22F3IO3S The following contents are mentioned in the article:

Treatment of RSiMe₃ [R = Ph, p-tolyl, 2,4,6-Me₃C₆H₂, p-BrC₆H₄, 4-(4-BrC₆H₄)C₆H₄] with iodosyl triflate gave 57-93% R₂I⁺聽^–OTf. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Electric Literature of C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Electric Literature of C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metal-free synthesis of diaryl sulfones from arylsulfinic acid salts and diaryliodonium salts was written by Umierski, Natalie;Manolikakes, Georg. And the article was included in Organic Letters in 2013.Formula: C19H22F3IO3S The following contents are mentioned in the article:

An efficient, high-yielding, and transition-metal-free synthesis of diaryl sulfones from arylsulfinic acid salts and diaryliodonium salts has been developed. The mild reaction conditions tolerate a range of functional groups, and unsym. diaryliodonium salts show high chemoselectivity. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-catalyzed direct oxidation and N-arylation of benzylamines with diaryliodonium salts was written by Liu, Xin;Mao, Dan;Wu, Sheng Ying;Yu, Jian Jun;Hong, Gang;Zhao, Qiao;Wang, Li Min. And the article was included in Science China: Chemistry in 2014.COA of Formula: C19H22F3IO3S The following contents are mentioned in the article:

An efficient synthesis of N-arylated amides is developed via copper(II) triflate-catalyzed direct oxidation of (aryl)methyl amines to primary arylamides by air and subsequent N-arylation by aryliodonium salts. The synthetic methodol. is convenient, practical and ecofriendly. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3COA of Formula: C19H22F3IO3S).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.COA of Formula: C19H22F3IO3S

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

tert-Butoxide mediated cascade desulfonylation/arylation/hydrolysis of cyclic sulfonyimines using diaryliodonium salts: synthesis of diaryl ether derivatives bearing a 2-aldehyde group was written by Qian, Xiaofei;Han, Jianwei;Wang, Limin. And the article was included in RSC Advances in 2016.Application of 139139-80-3 The following contents are mentioned in the article:

Cascades of cyclic sulfonylimines mediated by tBuOK with diaryliodonium salts giving the diaryl ethers in good yields were developed. Furthermore, bulky ortho-substituted diaryl ethers with an aldehyde group were obtained easily in comparision with metal-catalyzed protocols. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Application of 139139-80-3).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Application of 139139-80-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com