Tag: 300-400

In 2017,Lovinger, Gabriel J.; Morken, James P. published 《Ni-Catalyzed Enantioselective Conjunctive Coupling with C(sp3) Electrophiles: A Radical-Ionic Mechanistic Dichotomy》.Journal of the American Chemical Society published the findings.Computed Properties of C10H18INO2 The information in the text is summarized as follows:

The catalytic enantioselective conjunctive coupling of C(sp3) electrophiles can be accomplished with Ni catalysis. The enantioselectivity of the reaction is dependent on reaction mechanism with many substrates able to engage in an asym. process with Pybox-Ni complexes, whereas other substrates provide racemic product mixtures The link between substrate structure and selectivity is addressed. The results came from multiple reactions, including the reaction of tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Computed Properties of C10H18INO2)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Computed Properties of C10H18INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《meta-Selective C-H Activation of Arenes at Room Temperature Using Visible Light: Dual-Function Ruthenium Catalysis》 were Sagadevan, Arunachalam; Greaney, Michael F.. And the article was published in Angewandte Chemie, International Edition in 2019. HPLC of Formula: 301673-14-3 The author mentioned the following in the article:

Ruthenium-catalyzed meta-C-H activation of arenes at room temperature is reported to proceed under blue-light irradiation A variety of heteroarenes are compatible with this photochem. process, which leads to the corresponding meta C-C coupling products in good to very good yields. Initial mechanistic studies suggest a single-electron transfer process occurs between a photoexcited RuII-cyclometalated complex and alkyl halides, enabling meta-C-H functionalization reaction via carbon-centered radicals.tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3HPLC of Formula: 301673-14-3) was used in this study.

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.HPLC of Formula: 301673-14-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 301673-14-3In 2021 ,《Site-Selective C-H alkylation of Complex Arenes by a Two-Step Aryl Thianthrenation-Reductive Alkylation Sequence》 was published in Journal of the American Chemical Society. The article was written by Lansbergen, Beatrice; Granatino, Paola; Ritter, Tobias. The article contains the following contents:

Herein, an undirected para-selective two-step C-H alkylation of complex arenes e.g., I useful for late-stage functionalization is presented. The combination of a site-selective C-H thianthrenation with palladium-catalyzed reductive electrophile cross-coupling grants access to a diverse range of synthetically useful alkylated arenes e.g., II which cannot be accessed otherwise with comparable selectivity, diversity, and practicality. The robustness of this transformation is further demonstrated by thianthrenium-based reductive coupling of two complex fragments. The results came from multiple reactions, including the reaction of tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Application of 301673-14-3)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Application of 301673-14-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Photoinduced Palladium-Catalyzed Carbofunctionalization of Conjugated Dienes Proceeding via Radical-Polar Crossover Scenario: 1,2-Aminoalkylation and Beyond》 was published in Journal of the American Chemical Society in 2020. These research results belong to Shing Cheung, Kelvin Pak; Kurandina, Daria; Yata, Tetsuji; Gevorgyan, Vladimir. Related Products of 301673-14-3 The article mentions the following:

In the presence of PdCl2, Xantphos, and AgNTf2, 1,3-dienes such as (E)-1-phenyl-1,3-butadiene underwent regioselective and diastereoselective photochem. carboamination reactions with alkyl iodides such as Me3SiCH2I and amines such as N-methylbenzylamine mediated by Cs2CO3 in THF under blue LED irradiation to yield allylic amines such as (E)-PhCH:CHCH(NMeBn)CH2CH2SiMe3. The method is modular and does not require exogenous photosensitizers or oxidants. 4-Methylphenol and di-Et malonate were used as nucleophiles in two reactions instead of amines, yielding an allylic ether and a homoallylmalonate as products. Inhibition of the reaction by TEMPO (with isolation of its trapping products), formation of radical dimerization products in the absence of AgNTf2, and formation of cinnamylated TEMPO from cinnamylpalladium Xantphos complexes and TEMPO support a mechanism involving a putative π-allyl palladium radical-polar crossover. In the experiment, the researchers used many compounds, for example, tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Related Products of 301673-14-3)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Related Products of 301673-14-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com