Tag: 300-400

QSAR of nitro-diphenylethers as inhibitors of cyclic photophosphorylation was written by Oettmeier, Walter;Masson, Klaus;Donner, Andreas. And the article was included in Zeitschrift fuer Naturforschung in 1988.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:

Twenty-five nitro-diphenylethers were synthesized and assayed for their inhibitory activity in N-methylphenazonium-methosulfate-mediated cyclic photophosphorylation. Their pI₅₀-values ranged 3.5-5.3. A QSAR-anal. revealed that the lipophilicity of the nitro-diphenylethers as expressed by ∑π played a major role. In addition, the Taft steric parameter E_s in positions 6′, 4′ and 2′ (in decreasing order) contributed to the inhibitory activity. For maximal biol. activity, positions 4′ and 6′ should be left unsubstituted, whereas a bulky substituent is required for position 2′. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cellulose nanocrystals-palladium, a novel recyclable catalyst for coupling reaction was written by Seyednejhad, Sajedeh;Khalilzadeh, Mohammad A.;Sadeghifar, Hasan;Zareyee, Daryoush. And the article was included in Eurasian Chemical Communications in 2020.Synthetic Route of C12H8INO3 The following contents are mentioned in the article:

A new Schiff base catalyst (Pd(II) chem. mounted on the cellulose nanocrystals surface) was developed for Ullmann and Suzuki cross-coupling reactions. The catalyst was applied to the Ullmann reaction using a series of aryl halides and phenol derivatives in DMSO. The Suzuki cross-coupling reaction of aryl halides and phenylboronic acids gave biaryl compounds The catalyst was characterized by FTIR, XRD, SEM, ICP-AES and TGA techniques and demonstrated high reaction efficiency with more than 90% reaction yield. The catalyst could also be recovered and used several times and demonstrated good performance. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Synthetic Route of C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Synthetic Route of C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Palladium-Catalyzed Formation of Poly(imide-amides). 1. Reactions with Diiodo Imides and Diamines was written by Perry, Robert J.;Turner, S. Richard;Blevins, Richard W.. And the article was included in Macromolecules in 1994.Formula: C12H8INO3 The following contents are mentioned in the article:

High-mol.-weight poly(imide-amides) can be readily formed by the Pa-mediated carbonylation and condensation reactions of diiodo imide monomers and aromatic diamines. Reaction conditions for polymerization are 100-120°, 90 psig CO, 3-6% PdCl₂L₂ (L = PPh₃), and 2.4 equiv of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) for 2-4 h in DMAc or NMP. This route offers the flexibility of incorporating different ratios of amide and imide groups in the polymer backbone in a controlled manner. The imide moiety is preformed, which eliminates the possibility of postpolymn. curing. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Formula: C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Formula: C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-Catalyzed N,N-Diarylation of Amides for the Construction of 9,10-Dihydroacridine Structure and Applications in the Synthesis of Diverse Nitrogen-Embedded Polyacenes was written by Tan, Mei-Ling;Tong, Shuo;Hou, Sheng-Kai;You, Jingsong;Wang, Mei-Xiang. And the article was included in Organic Letters in 2020.Category: iodides-buliding-blocks The following contents are mentioned in the article:

A CuI/DMEDA catalyzed N,N-diarylation reaction of amides with various di(o-bromoaryl)methanes to produce diverse 9,10-dihydroacridine derivatives, is reported. The resulting 9,10-dihydroacridine derivatives were oxidized selectively under mild conditions to afford acridine, acridinone, and acridinium derivatives The copper-catalyzed N,N-diarylation reaction coupled with oxidative aromatization reaction enabled the facile construction of nitrogen atom-embedded tetracenes and pentacenes of different ortho-fused patterns. The luminescence properties, especially the effect of fusion pattern on fluorescence emission of acquired N-polyacenes, were also demonstrated. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Category: iodides-buliding-blocks).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Design and Synthesis of a Novel Series of Bicyclic Heterocycles As Potent γ-Secretase Modulators was written by Bischoff, Francois;Berthelot, Didier;De Cleyn, Michel;MacDonald, Gregor;Minne, Garrett;Oehlrich, Daniel;Pieters, Serge;Surkyn, Michel;Trabanco, Andres A.;Tresadern, Gary;Van Brandt, Sven;Velter, Ingrid;Zaja, Mirko;Borghys, Herman;Masungi, Chantal;Mercken, Marc;Gijsen, Harrie J. M.. And the article was included in Journal of Medicinal Chemistry in 2012.HPLC of Formula: 1232038-69-5 The following contents are mentioned in the article:

The design and the synthesis of several chem. subclasses of imidazole containing γ-secretase modulators (GSMs) is described. Conformational restriction of an aminopyridone into bicyclic pyridone isosteres has led to compounds with high in vitro and in vivo potency. This has resulted in the identification of benzimidazole I as a GSM with low nanomolar potency in vitro. In mouse, rat, and dog, this compound displayed the typical γ-secretase modulatory profile by lowering Aβ42 and Aβ40 levels combined with an especially pronounced increase in Aβ38 and Aβ37 levels while leaving the total levels of amyloid peptides unchanged. This study involved multiple reactions and reactants, such as 8-Bromo-3-iodoimidazo[1,2-a]pyridine (cas: 1232038-69-5HPLC of Formula: 1232038-69-5).

8-Bromo-3-iodoimidazo[1,2-a]pyridine (cas: 1232038-69-5) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). HPLC of Formula: 1232038-69-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Novel Synthesis of Benzalacetone Analogues of Naphth[a]azulenes by Intramolecular Tropylium Ion-Mediated Furan Ring-Opening Reaction and X-ray Investigation of a Naphth[1,2-a]azulene Derivative was written by Yamamura, Kimiaki;Kawabata, Shizuka;Kimura, Takatomo;Eda, Kazuo;Hashimoto, Masao. And the article was included in Journal of Organic Chemistry in 2005.Computed Properties of C10H6BrI The following contents are mentioned in the article:

Benzalacetone analogs of naphth[1,2-a]azulene (I), naphth[2,1-a]azulene, and naphth[2,3-a]azulene were synthesized from 2-(5-methyl-2-furyl)-1-, 1-(5-methyl-2-furyl)-2-, and 2-(5-methyl-2-furyl)-3-tropylionaphthalene, resp. The synthetic method is based on furan ring-opening reaction by the intramol. electrophilic attack of a tropylium ion. Single-crystal X-ray work on I revealed that its tetracyclic system exhibited deformation from planarity similar to that of benzo[c]phenanthrene (tetrahelicene). A centrosym. associated dimer structure, just like the mols. of carboxylic acids but via C:O···H-C hydrogen bonds, was found in the crystal. Reduction of bond-length alternation in the seven-membered ring was also found. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Computed Properties of C10H6BrI).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Computed Properties of C10H6BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Compounds of the type C₆H₅XC₆H₅. I. Electric dipole moments of some 4-substituted 4′-nitrodiphenyl ether and di-phenyl sulfide derivatives was written by Rolla, Mario;Sanesi, Manlio. And the article was included in Ric. Sci. Rend. in 1961.Reference of 21969-05-1 The following contents are mentioned in the article:

Elec. dipole moments of derivatives of Ph₂O and Ph₂S were measured in a benzene solution at 20°. The compounds and results (in Debyes) were for Ph₂O: 4-CH₃-4′-NO₂ (4.70) 4-F-4′-NO₂ (3.34); 4-Cl-4′-NO₂ (3.17); 4-Br-4′-NO₂ (4.23); 4-I-4′-NO₂ (3.34); 4-CN-4′-NO₂ (2.71); 4-CN (4.23D.); and for Ph₂S: 4-CH₃-4′-NO₂ (4.67); 4-F-4′-NO₂ (3.54); 4-Cl-4′-NO₂ (3.40); 4-Br-4′-NO₂ (3.42); 4-I-4′-NO₂ (3.52); 4-CN-4′-NO₂ (3.36); 4-CN (4.14). Overall tendencies in the 2 series were similar. Halogen derivatives in both series had similar dipole moments. 30 references. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Reference of 21969-05-1).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Reference of 21969-05-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bronsted acid-enhanced copper-catalyzed atroposelective cycloisomerization to axially chiral arylquinolizones via dearomatization of pyridine was written by Min, Xiao-Long;Zhang, Xiu-Lian;Yi, Wenbin;He, Ying. And the article was included in Nature Communications in 2022.Quality Control of 2-Bromo-1-iodonaphthalene The following contents are mentioned in the article:

Herein, the enantioselective synthesis of axially chiral arylquinolizones through an intramol. atroposelective cycloisomerization was reported. The reaction proceeds via the Bronsted acid-enhanced dearomatization of pyridine by a copper catalyst that allows for the formation of the desired products in excellent yields and enantioselectivities. The utility of this methodol. was illustrated by a synthesis on gram scale production and transformation of the products into chiral thiourea catalysts. Mechanistic studies demonstrate that Bronsted acid plays a significant role in promoting the reactivity of the reaction, while both the steric and electronic effects of aryl substituents in substrate play a role in controlling the stereoselectivity. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Quality Control of 2-Bromo-1-iodonaphthalene).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Quality Control of 2-Bromo-1-iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Compounds of the type C₆H₅-X-C₆H₅. II. Group and bond moments in 4-Y,4′-NO₂ derivatives of diphenyl ether and diphenyl sulfide was written by Rolla, Mario;Sanesi, Manlio. And the article was included in Ricerca Scientifica, Parte 2: Rendiconti, Sezione A: Abiologica in 1961.Electric Literature of C12H8INO3 The following contents are mentioned in the article:

cf. ibid. 43. A semiquant. method is proposed for the evaluation of group and bond moments of p-YC₆H₄OC₆H₄NO₂-p (I) and p-YC₆H₄SC₆H₄NO₂-p (II) (where Y = Me, F, Cl, Br, I, CN, and NO₂) from known dipole moments and bond angles. In these compounds the degree of conjugation of the NO₂ group is higher than in PhNO₂, but slightly lower than in p-O₂NC₆H₄OPh and p-O₂NC₆H₄SPh; halogen conjugation is lower than in the corresponding C₆H₆ derivatives, but higher than in p-YC₆H₄OPh and p-YC₆H₄SPh. I and II (Y = CN or NO₂) show much lower apparent conjugation than expected. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Electric Literature of C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Electric Literature of C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rhodium-Catalyzed Enantioselective Synthesis, Structures, and Properties of Single and Double Azahelicene-Like Molecules was written by Hanada, Kyoichi;Nogami, Juntaro;Miyamoto, Kazunori;Hayase, Norihiko;Nagashima, Yuki;Tanaka, Yusuke;Muranaka, Atsuya;Uchiyama, Masanobu;Tanaka, Ken. And the article was included in Chemistry – A European Journal in 2021.SDS of cas: 676267-05-3 The following contents are mentioned in the article:

The enantioselective synthesis of aza[6] and [7]helicene-like mols. have been achieved by the cationic rhodium(I)/axially chiral biaryl bisphosphine complex-catalyzed intramol. [2+2+2] cycloaddition of cyanodiynes [e.g., I → (P)-II (optimized at 87%, 62% ee using (R)-xyl-segphos)]. This protocol was successfully applied to the diastereo- and enantioselective synthesis of an S-shaped double aza[6]helicene-like mol. with a high ee value of 89%. Although no epimerization and racemization were observed in the double carbo[6]helicene-like mol. at 80°C, epimerization and racemization of the double aza[6]helicene-like mol. proceeded at 80°C. This double aza[6]helicene-like mol. showed good fluorescent quantum yields and chiroptical responses under both neutral and acidic conditions. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3SDS of cas: 676267-05-3).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.SDS of cas: 676267-05-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com