Tag: 300-400

Iron-catalyzed oxidative biaryl cross-couplings via mixed diaryl titanates: significant influence of the order of combining aryl Grignard reagents with titanate was written by Liu, Kun Ming;Wei, Juan;Duan, Xin Fang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Application of 77350-52-8 This article mentions the following:

Mixed diaryl titanates were used for the first time to modify the reactivity of two aryl Grignard reagents. Two titanate intermediates, Ar[Ar’Ti(OR)₃]MgX and Ar'[ArTi(OR)₃]MgX, formed by alternating the sequence of combining Grignard reagents with ClTi(OR)₃ showed a significant reactivity difference. Taking advantage of such different reactivity, two highly structurally similar aryl groups could be easily assembled through iron-catalyzed oxidative cross-coupling reactions using oxygen as an oxidant. The synthesis of the target compounds was achieved by a reaction of (chloro)[2,2′-(oxy)bis[ethanolato]](2-propanolato)titanium with Grignard reagents. For example, (4-methoxyphenyl)magnesium bromide was added first and (4-methylphenyl)magnesium bromide was added second, thus, to provide a (methylphenyl)(methoxyphenyl)titanate. A titanate complex of different reactivity was obtained if the order of addition of the above-mentioned Grignard reagents was reversed. Depending on reaction conditions the products formed were thus 4,4′-dimethoxy-1,1-biphenyl or 4-methoxy-4′-methyl-1,1′-biphenyl or 4,4′-dimethyl-1,1-biphenyl. Other products included 4′-methyl[1,1′-biphenyl]-4-carboxylic acid ester, 1-(2-methylphenyl)naphthalene, [1,1′-biphenyl]-2-carbonitrile, 4-(2-thienyl)benzaldehyde (thiophene derivative). In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Application of 77350-52-8).

N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Application of 77350-52-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus was written by Bahnous, Mebarek;Bouraiou, Abdelmalek;Chelghoum, Meryem;Bouacida, Sofiane;Roisnel, Thierry;Smati, Farida;Bentchouala, Chafia;Gros, Philippe C.;Belfaitah, Ali. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Product Details of 15813-09-9 This article mentions the following:

Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole, and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Product Details of 15813-09-9).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 15813-09-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-catalyzed trifluoromethylation of aryl iodides with potassium (trifluoromethyl)trimethoxyborate was written by Knauber, Thomas;Arikan, Fatih;Roeschenthaler, Gerd-Volker;Goossen, Lukas J.. And the article was included in Chemistry – A European Journal in 2011.HPLC of Formula: 77350-52-8 This article mentions the following:

Potassium (trifluoromethyl)trimethoxyborate is introduced as a new source of CF₃ nucleophiles in copper-catalyzed trifluoromethylation reactions. The crystalline salt is stable on storage, easy to handle, and can be obtained in near-quant. yields simply by mixing B(OMe)₃, CF₃SiMe₃, and KF. The trifluoromethylation reagent allows the conversion of various aryl iodides into the corresponding benzotrifluorides in high yields under mild, base-free conditions in the presence of catalytic quantities of a Cu^I/1,10-phenanthroline complex. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8HPLC of Formula: 77350-52-8).

N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.HPLC of Formula: 77350-52-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodination of aromatic compounds by N-iodosuccinimide in organic solvents in the presence of H₂SO₄ was written by Chaikovski, V. K.;Filimonov, V. D.;Skorokhodov, V. I.. And the article was included in Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya in 2002.HPLC of Formula: 3268-21-1 This article mentions the following:

N-iodosuccinimide in organic solvents in the presence of small amounts of H₂SO₄ easily iodinates alkylbenzenes, arylamines, phenols and some polycyclic hydrocarbons with high yields of products at 0-20°. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1HPLC of Formula: 3268-21-1).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.HPLC of Formula: 3268-21-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Self-Assembly of M₃₀L₆₀ Icosidodecahedron was written by Fujita, Daishi;Ueda, Yoshihiro;Sato, Sota;Yokoyama, Hiroyuki;Mizuno, Nobuhiro;Kumasaka, Takashi;Fujita, Makoto. And the article was included in Chem in 2016.Synthetic Route of C10H12I2 This article mentions the following:

Self-assembly is invaluable in the construction of giant mol. structures via a bottom-up approach. Although living organisms naturally make the most use of self-assembly and freely handle the mechanism at will, scientists are still far behind the level of nature. Inspired by the elegant structures of virus capsids, the authors have previously constructed roughly spherical giant metal complexes with the symmetry of an octahedron, cuboctahedron, and rhombicuboctahedron M₆L₁₂, M₁₂L₂₄, and M₂₄L₄₈, resp. Here, the authors report the 1st successful synthesis of an M₃₀L₆₀ mol. icosidodecahedron that consists of âˆ?00 components: 30 Pd(II) ions and 60 (2,5-bis(4-pyridyl-1,4-tetramethylphenylene)thiophene) ligands that assemble into the largest well-defined spherical macromol. to date (diameter of âˆ?.2 nm). Tuning the flexibility of the ligand was the key for successful self-assembly. A highly complex but sym. organized structure was identified through x-ray crystallog. anal. The interior space of the mol. complex is large enough (157,000 ų) to enclose proteins. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Synthetic Route of C10H12I2).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Synthetic Route of C10H12I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Polyiodoimidazoles and their nitration products was written by Katritzky, A. R.;Cundy, D. J.;Chen, J.. And the article was included in Journal of Energetic Materials in 1993.Electric Literature of C3H2I2N2 This article mentions the following:

The preparations of 4,5-diiodoimidazole and 2,4,5-triiodoimidazole from imidazole were reinvestigated and convenient procedures with excellent yields described. 2,4,5-Triiodoimidazole can be selectively converted to 2,4(5)-dinitro-5(4)-iodoimidazole and 2,4,5-trinitroimidazole by nitrolysis. 2,4(5)-Dinitroimidazole was converted by nitration into 2,4,5-trinitroimidazole and isolated as the imidazolium and potassium salts in 38% and 15% yields resp. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Electric Literature of C3H2I2N2).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Electric Literature of C3H2I2N2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Polyfunctionalization of imidazole via sequential imidazolyl anion formation was written by Carver, David S.;Lindell, Stephen D.;Saville-Stones, Elizabeth A.. And the article was included in Tetrahedron in 1997.Product Details of 15813-09-9 This article mentions the following:

A method for achieving the sequential functionalization of the imidazole ring in the order C-5→C-4→C-2 is described. The chem. proceeds via the regioselective formation of positionally stable imidazolyl anions which react with electrophiles (aldehydes, alkyl halides, azides, formamides, isocyanates) to afford substituted imidazoles in 31-90% yield. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Product Details of 15813-09-9).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Product Details of 15813-09-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Practical synthesis of 2-iodosobenzoic acid (IBA) without contamination by hazardous 2-iodoxybenzoic acid (IBX) under mild conditions was written by China, Hideyasu;Kageyama, Nami;Yatabe, Hotaka;Takenaga, Naoko;Dohi, Toshifumi. And the article was included in Molecules in 2021.Formula: C7H4BrIO2 This article mentions the following:

A convenient and practical method for the preparation of nonexplosive cyclic hypervalent iodine(III) oxidants as efficient organocatalysts and reagents for various reactions using oxone in aqueous solution under mild conditions at room temperature is reported. The thus obtained 2-iodosobenzoic acids (IBAs) could be used as precursors of other cyclic organoiodine(III) derivatives by the solvolytic derivatization of the hydroxy group under mild conditions of 80° or lower temperature These sequential procedures are highly reliable to selectively afford cyclic hypervalent iodine compounds in excellent yields without contamination by hazardous pentavalent iodine(III) compound In the experiment, the researchers used many compounds, for example, 3-Bromo-2-iodobenzoic acid (cas: 503821-94-1Formula: C7H4BrIO2).

3-Bromo-2-iodobenzoic acid (cas: 503821-94-1) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C7H4BrIO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Opening Metal-Organic Frameworks Volume 2: Inserting Longer Pillars into Pillared-Paddlewheel Structures through Solvent-Assisted Linker Exchange was written by Karagiaridi, Olga;Bury, Wojciech;Tylianakis, Emmanuel;Sarjeant, Amy A.;Hupp, Joseph T.;Farha, Omar K.. And the article was included in Chemistry of Materials in 2013.Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene This article mentions the following:

Solvent-assisted linker exchange (SALE) was performed on a pillared-paddlewheel metal-organic framework (MOF), SALEM-5, to achieve incorporation of longer linkers into the material. The 9-Å meso-1,2-di(4-pyridyl)-1,2-ethanediol pillar of SALEM-5 was successfully replaced by 11-Å, 14-Å, and 17-Å pillars to generate daughter MOFs SALEM-6, SALEM-7, and SALEM-8. The daughter frameworks possess more open cages, as was demonstrated by structural modeling from the powder x-ray diffraction patterns, and larger solvent accessible space, as was demonstrated by TGA. Finally, a study was performed to examine the effect of pK_a of monoprotonated dipyridyl pillars (as an indicator of the Zn-L bond strength) on the outcome of SALE. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Durene-decorated CBP derivatives as phosphorescent hosts and exciton-blocking materials for efficient blue OLEDs was written by Deng, Lijun;Wang, Xinzeng;Zhang, Zhengchuan;Li, Jiuyan. And the article was included in Journal of Materials Chemistry in 2012.HPLC of Formula: 3268-21-1 This article mentions the following:

Two novel durene-containing mols., 1,4-bis[4-(9-carbazolyl)phenyl]durene (CPD) and 1,4-bis{4-[9-(3,6-(di-tert-butyl)carbazoyl)]phenyl}durene (Me₃CCPD), which are derived from 4,4′-bis(9-carbazolyl)biphenyl (CBP) by inserting durene in its biphenyl core, are designed and synthesized for use as host materials for blue phosphors in organic LEDs (OLEDs). Inserting durene in biphenyl causes a right-angle torsion between the durene and the adjacent Ph groups due to the strong steric hindrance effect of the durene group, confining the effective π-conjugation on only one carbazole and 1 Ph and increasing the triplet energies of CPD and Me₃CCPD to >3.0 eV. These durene-decorated mols. show higher thermal stabilities than many other CBP derivatives Blue phosphorescent OLEDs were fabricated using CPD and Me₃CCPD as triplet hosts and traditional Ir(III) bis(4,6-(difluorophenyl)pyridinato-N,C^2′)picolinate (FIrpic) as a dopant and excellent performances were achieved. In particular, peak efficiencies of 26.2 cd A^-1 and 14.8 lm W^-1 were realized when CPD was used as both a host and exciton-blocking material. This is the 1st report using durene to tune the triplet energy levels of phosphorescent host materials. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1HPLC of Formula: 3268-21-1).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.HPLC of Formula: 3268-21-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com