Tag: 200-300

The author of 《The crystal structure of 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine: a three-dimensional hydrogen-bonded framework, augmented by π-π stacking interactions and I···N halogen bonds》 were Mahesha, Ninganayaka; Yathirajan, Hemmige S.; Furuya, Tetsundo; Akitsu, Takashiro; Glidewell, Christopher. And the article was published in Acta Crystallographica, Section E: Crystallographic Communications in 2019. Electric Literature of C7H5IO2 The author mentioned the following in the article:

In 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine, C15H15IN4O, the central piperazine ring adopts an almost perfect chair conformation with the pyrimidine substituent in an equatorial site. The planar amide unit makes a dihedral angle of 80.44 (7)° with the Ph ring. A combination of C-H···O and C-H···Π(arene) hydrogen bonds links the mols. into a complex three-dimensional network structure, augmented by a π-π stacking interaction and an I···N halogen bond, all involving different pairs of inversion-related mols. Comparisons are made with the structures of a number of related compounds In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5Electric Literature of C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Electric Literature of C7H5IO2 In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Materials Science & Engineering, C: Materials for Biological Applications included an article by Veisi, Hojat; Ghorbani, Milad; Hemmati, Saba. Synthetic Route of C7H7I. The article was titled 《Sonochemical in situ immobilization of Pd nanoparticles on green tea extract coated Fe3O4 nanoparticles: An efficient and magnetically recyclable nanocatalyst for synthesis of biphenyl compounds under ultrasound irradiations》. The information in the text is summarized as follows:

This work describes (i) an eco-friendly approach for in situ immobilization of Pd nanoparticles on the surface of Fe3O4 nanoparticles, with help of green tea extract and ultrasound irradiations, without using any toxic reducing agents and (ii) development of ultrasound assisted simple protocol for synthesis of biphenyl compds RC6H5 (R = C6H5, 4-C(O)CH3C6H4, 2-thienyl, etc.). The structural, morphol. and physicochem. characteristics of the catalyst were determined by different anal. methods including inductively coupled plasma (ICP) anal., Fourier transform IR spectroscopy (FT-IR), field emission SEM (FESEM), energy dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), XPS and vibrating sample magnetometry (VSM). Catalytic performance of Pd/Fe3O4 NPs as magnetic and heterogeneous catalyst was evaluated in synthesis of various biphenyl compounds throughout Suzuki coupling reactions by using the ultrasound-assisted method that was developed in this study. The Pd/Fe3O4 NPs demonstrated a noticeable catalytic activity by giving high product yields. Furthermore, the heterogeneous nanocatalyst was successfully recovered up to six times without significant activity loss. Addnl., with respect to conventional coupling reactions, the ultrasound-assisted synthesis reactions presented the advantages of green conditions, short reaction times, high yields and easier work-up. In the experiment, the researchers used many compounds, for example, 1-Iodo-4-methylbenzene(cas: 624-31-7Synthetic Route of C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Synthetic Route of C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Product Details of 15164-44-0In 2020 ,《UV-visible and fluorescence spectroscopic assessment of meso-tetrakis-(4-halophenyl) porphyrin; H2TXPP (X = F, Cl, Br, I) in THF and THF-water system: Effect of pH and aggregation behaviour》 was published in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The article was written by Dar, Umar Ali; Shah, Shakeel A.. The article contains the following contents:

The current study determines optical and fluorescence response of halogen substituted series of meso-tetrakis-(4-halophenyl) porphyrin; H2TXPP (Halo = F, Cl, Br, I) dye in tetrahydrofuran; THF and THF-water system at changing pH in relationship with changing medium of allure. Effects produced by varying the pH and medium, over spectral and aggregation were discussed in detail. Results show sequential protonation and deprotonation of H2TXPP series in acidic (pH = 4) and (pH =10) basic medium. Specific structural changes of monomeric absorption band were put in evidence on lowering pH, which includes broadening and splitting of soret or B band. Other changes include increasing in intensity and red-shifting of Q1 band indicating some degree of aggregation. The side-by-side aggregation and formation of J-aggregate were quite evident. The red shift of B band featured self-aggregation through head-to-tail mol. ordering which is consonant with absorption-emission data. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Product Details of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Product Details of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sharipov, Bulat T.; Davidova, Anna N.; Valeev, Farid A. published an article in 2022. The article was titled 《cis-Annulation of an oxazoline fragment to levoglucosenone and the synthesis of 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranose》, and you may find the article in Chemistry of Heterocyclic Compounds (New York, NY, United States).COA of Formula: C4H4INO2 The information in the text is summarized as follows:

Chiral 2-trichloromethyl-oxazolines 4,5-cis-annulated to a carbohydrate fragment were synthesized on the basis of levoglucosenone. The synthesized compounds were converted by acid hydrolysis into 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranoses. Intramol. amination of allyl trichloroacetimidates by electrophilic reagents was used to construct the oxazoline ring. It was established that trichloroacetimidates containing an epoxide ring in α,β-positions spontaneously undergo re-cyclization with the formation of an oxazoline ring. In addition to this study using 1-Iodopyrrolidine-2,5-dione, there are many other studies that have used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1COA of Formula: C4H4INO2) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. COA of Formula: C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reference of 1-Chloro-4-iodo-2-nitrobenzeneOn October 31, 2016 ,《Pd-catalyzed coupling reaction of 6-hydroxy-2-(prop-2-yn-1-ylsulfanyl)pyrimidin-4(1H)-one with aryl iodides: efficient syntheses of new 3-benzylthiazolo[3,2-a]pyrimidinones》 appeared in Chemistry of Heterocyclic Compounds (New York, NY, United States). The author of the article were Keivanloo, Ali; Bakherad, Mohammad; Shahani, Taraneh; Amin, Amir Hossein. The article conveys some information:

An efficient synthetic protocol was developed for the preparation of 3-benzyl-7(5)-hydroxy-5(7)H-[1,3]thiazolo[3,2-a]pyrimidin-5(7)-ones from 6-hydroxy-2-(prop-2-yn-1-ylthio)pyrimidin-4(1H)-one and aryl iodides in the presence of Pd-Cu complex catalyst. This one-pot process provides a simple and direct method for the synthesis of new thiazolo[3,2-a]pyrimidinones in good to high yields. In the experiment, the researchers used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Reference of 1-Chloro-4-iodo-2-nitrobenzene Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Essential oils constituents, phytochemical analyses, and antimicrobial studies on leaf and stem of Thunbergia laevis Nees》 was written by Olaoluwa, Olaoluwa Omosalewa; Moronkola, Dorcas Olufunke; Kwenga, Sichilongo; Mgbeoji, Okwu. COA of Formula: C2H4I2This research focused onThunbergia leaf stem essential oil phytochem antimicrobial. The article conveys some information:

Essential oils of leaf and stem of Thunbergia laevis were obtained by Clevenger-type apparatus, their chem. constituents were analyzed using gas chromatog. [GC] and gas chromatog.-mass spectrometry [GC-MS]. Hexane and ethanol extracts from leaf and stem of Thunbergia laevis were obtained by cold extraction and screened for phytochem. constituents. Antimicrobial activities of these oils, hexane and ethanol extracts were carried out against six bacteria and four fungi. Forty-six compounds identified in leaf oil account for 62.58% of it, dominated by phytol (4.10%) and i-Pr hexadecanoate (3.19%); ten compounds in stem oil represent 62.40% of it, with most abundant methoxyl-phenyl-oxime (23.45%) and Z-11- hexadecenoic acid (12.28%). Leaf oil mostly contains hydrocarbons and esters, while stem oil have aromatic derivatives and acids. Antimicrobial studies of leaf oil caused strong inhibition in growth of Staphylococcus aureus and Candida albicans at concentration between 25 – 100% with the zone of inhibition ranging between 20 -28 mm and 14 – 18 mm resp. Stem oil was most active on Candida albicans and Asprgillus niger at the same concentration with zone of inhibition of 14 – 18 mm and 12 – 18 mm resp. Alkaloids, tannins, saponins, resins, phenols and terpenoids were observed in leaf and stem ethanol extracts Leaf ethanol extract was most active on Staphylococcus aureus, Candida albicans and Rhizopus stolonifer. Stem ethanol extract moderately inhibited growth of these microorganisms. This study is on Thunbergia laevis leaf and stem essential oils constituents, phytochem. and antimicrobial analyses, which have not been earlier reported in literature. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7COA of Formula: C2H4I2) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.COA of Formula: C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com