Tian, Zhenhao’s team published research in Journal of Materials Chemistry B: Materials for Biology and Medicine in 2019 | CAS: 516-12-1

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 516-12-1

The author of 《A highly sensitive and selective two-photon fluorescent probe for glutathione S-transferase detection and imaging in living cells and tissues》 were Tian, Zhenhao; Tian, Xiangge; Feng, Lei; Tian, Yan; Huo, Xiaokui; Zhang, Baojing; Deng, Sa; Ma, Xiaochi; Cui, Jingnan. And the article was published in Journal of Materials Chemistry B: Materials for Biology and Medicine in 2019. Recommanded Product: 516-12-1 The author mentioned the following in the article:

Glutathione transferase (GST) is a very important metabolic enzyme that mediates the wide metabolism of endogenous and xenobiotic compounds; it usually has a significant over expression in cancer cells, which is a key reason resulting in drug resistance, and will show an obvious down regulation during liver injury, thus it was also regarded as a vital biomarker in clin. diagnosis. Herein, based on boron-dipyrromethene (BODIPY) dye, a two-photon probe BNPA was designed for the real-time detection of GST activities and fluorescence imaging in both cancer cells and liver tissues. Importantly, BNPA exhibited a high selectivity, ultrahigh imaging resolution and showed a classic Michaelis-Menten kinetics toward GSTs. Furthermore, it was successfully used for monitoring the GST activities in living cells and deep tissues by two-photon imaging, as well as detecting the down regulation of GST activities during α-naphthylisothiocyanate (ANIT) induced liver injury. Our results fully demonstrated that BNPA could serve as a promising tool for evaluating the GST function and the process of cellular GSTs in living systems, and also provided a new approach for studying GST-associated liver diseases, which would be greatly useful for rational drug use and disease diagnosis in clinics.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lin, Xiongjie’s team published research in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2019 | CAS: 516-12-1

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

In 2019,Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy included an article by Lin, Xiongjie; Tang, Danting; He, Tian; Xu, Zheng; Qiu, Huayu; Zhang, Qian; Yin, Shouchun. Application of 516-12-1. The article was titled 《A series of novel BODIPY-fluorene copolymers: Synthesis, characterization, optical-electronic and nonlinear optical properties》. The information in the text is summarized as follows:

A series of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) with different connection sites and conjugation length and fluorene alternating conjugated polymers have been synthesized via palladium-catalyzed Suzuki coupling reaction. The polymers were fully characterized by 1H NMR spectroscopy and gel permeation chromatog. (GPC), and their properties were measured by thermogravimetric anal. (TGA), UV-vis absorption spectroscopy, cyclic voltammetry (CV), photoluminescence (PL) spectroscopy, the Z-scan technique, and theor. calculation using d.-functional theory (DFT) method. The results indicate that the connection sites and conjugation length of BODIPY have great effect on the optical-electronic and nonlinear optical properties of the conjugated BODIPY- fluorene copolymers although they don’t affect the polymerization process. The absorption and emission peaks of P1 exhibit red shifts compared to those of P2 and P3. The polymers show good nonlinear optical properties that are closely related to the connection sites of the BODIPY pendants. P1 exhibits relatively richer nonlinear optical (NLO) properties than P2 and P3. The third order nonlinear optical coefficient (χ(3)) of P1 is 3.57 × 10-11 esu, which is ∼4 times larger than those of P2 and P3. In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bui, Thi Thoi’s team published research in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences in 2021 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 2-Iodobenzoic acid

Name: 2-Iodobenzoic acidIn 2021 ,《Synthesis and evaluation of α-glucosidase inhibitory activity of sulfonylurea derivatives》 was published in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences. The article was written by Bui, Thi Thoi; Tran, Van Loc; Ngo, Dai Quang; Tran, Van Chien; Tran, Van Sung; Tran, Thi Phuong Thao. The article contains the following contents:

Two series of sulfonylureas derivatives include 24 compounds I (R = NH2, phenylamidyl, (3-methylpyridin-2-yl)amidyl, (quinoxalin-2-yl)amidyl, etc.) and II (R1 = OEt, cyclopentylaminyl, benzylaminyl, (2,3,4-trifluorophenyl)aminyl, etc.), among them, 17 new derivatives, have been synthesized and evaluated for their α-glucosidase inhibitory activity. Compounds I (R = (2E)-3-(4-hydroxyphenyl)prop-2-enamidyl; R = (2-hydroxy-3,5-diiodophenyl)amidyl) and II (R1 = [4-nitro-3-(trifluoromethyl)phenyl]aminyl) showed significant in vitro α-glucosidase inhibition with IC50 values of 5.58, 79.85 and 213.36μm, resp., comparing with the standard compounds acarbose (IC50 = 268.29μm) and glipizide (IC50 = 300.47μm). The preliminary structure-activity relationships (SARs) of the synthesized compounds I and II were also investigated.2-Iodobenzoic acid(cas: 88-67-5Name: 2-Iodobenzoic acid) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 2-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad’s team published research in Phosphorus, Sulfur and Silicon and the Related Elements in 2011 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Reference of 1-Chloro-4-iodo-2-nitrobenzene Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

The author of 《Pd-Catalyzed Heterocyclization During Sonogashira Coupling: Synthesis of 3-Aryl-substituted Imidazo[2,1-b]thiazoles》 were Bakherad, Mohammad; Keivanloo, Ali; Nasr-Isfahani, Hossein; Raeissi, Mersad. And the article was published in Phosphorus, Sulfur and Silicon and the Related Elements in 2011. Reference of 1-Chloro-4-iodo-2-nitrobenzene The author mentioned the following in the article:

The reaction of 4,5-diphenyl-2-propargylmercaptoimidazole with various aryl iodides catalyzed by Pd-Cu in the presence of triethylamine as base in DMF leads to the formation of 3-aryl-substituted imidazo[2,1-b]thiazoles, e.g, I. In the experiment, the researchers used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Reference of 1-Chloro-4-iodo-2-nitrobenzene Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Halka, Mariya’s team published research in Plant Physiology and Biochemistry (Issy-les-Moulineaux, France) in 2019 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

SDS of cas: 88-67-5In 2019 ,《Iodine biofortification through expression of HMT, SAMT and S3H genes in Solanum lycopersicum L.》 was published in Plant Physiology and Biochemistry (Issy-les-Moulineaux, France). The article was written by Halka, Mariya; Smolen, Sylwester; Czernicka, Malgorzata; Klimek-Chodacka, Magdalena; Pitala, Joanna; Tutaj, Krzysztof. The article contains the following contents:

The uptake process and physiol. reaction of plants to aromatic iodine compounds have not yet been documented. The aim of this research was to compare uptake by tomato plants of KI and KIO3, as well as of organic iodine compounds – 5-ISA (5-iodosalicylic acid), 3,5-diISA (3,5-diiodosalicylic acid), 2-IBeA (2-iodobenzoic acid), 4-IBeA (4-iodobenzoic acid) and 2,3,5-triIBeA (2,3,5-triiodobenzoic acid). Only 2,3,5-triIBeA had a neg. influence on plant development. All organic iodine compounds were taken up by roots and transported to leaves and fruits. Among all the compounds applied, the most efficiently transferred iodine was 2-IBeA – to fruits, and 4-IBeA – to leaves. The order of iodine accumulation in fruit cell compartments was as follows: organelles > cell walls > soluble portions of cells; for leaf and root cells, it was: organelles > cell walls or soluble portions, depending on the compound applied. The compounds studied influence iodine metabolism through expression of the HMT gene which encodes halide ion methyltransferase in leaves and roots. Also, their influence on modification of the activity of the SAMT and S3H genes that encode salicylic acid carboxyl methyltransferase and salicylic acid 3-hydroxylase was established. It was discovered that exogenously applied 5-ISA, 3,5-diISA, 2-IBeA and 4-IBeA are genuinely (endogenously) synthesized in tomato plants; to date, this has not been described for the tomato, nor for any other species of higher plant. In the part of experimental materials, we found many familiar compounds, such as 2-Iodobenzoic acid(cas: 88-67-5SDS of cas: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Firouzeh, Ebrahim’s team published research in Journal of Photochemistry and Photobiology, A: Chemistry in 2022 | CAS: 15164-44-0

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Product Details of 15164-44-0

In 2022,Firouzeh, Ebrahim; Kazemi, Foad; Gholinejad, Mohammad; Kaboudin, Babak published an article in Journal of Photochemistry and Photobiology, A: Chemistry. The title of the article was 《Visible photosensitized sonogashira-hagihara coupling through in situ prepared palladium catalyst in N,N-dimethylformamide under copper and amine-free additives》.Product Details of 15164-44-0 The author mentioned the following in the article:

In this study, copper and amine-free photosensitized Sonogashira-Hagihara coupling reaction using Pd(OAc)2 and p-nitrobenzophenone in N,N-dimethylformamide(DMF) under blue LED irradiation was reported. Effect of benzophenone, p-methoxybenzophenone and p-nitrobenzophenone as photosensitizers in Sonogashira-Hagihara reaction were studied in which higher yields were achieved using p-nitrobenzophenone. In situ preparation of palladium nanoparticles and the effect of p-nitrobenzophenone were confirmed using UV-Vis and dynamic light scattering (DLS). It was proposed that the DMF affected the formation and stabilization of palladium nanoparticles. Using this catalytic system, aryl iodides and bromides were reacted efficiently with alkynes between 25 and 60°C. In the experimental materials used by the author, we found 4-Iodobenzaldehyde(cas: 15164-44-0Product Details of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Product Details of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Golebiewska, Justyna’s team published research in Phosphorus, Sulfur and Silicon and the Related Elements in 2022 | CAS: 516-12-1

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Computed Properties of C4H4INO2

In 2022,Golebiewska, Justyna; Bartoszewicz, Agnieszka; Kalek, Marcin; Stawinski, Jacek published an article in Phosphorus, Sulfur and Silicon and the Related Elements. The title of the article was 《Second generation of nucleotide analogs》.Computed Properties of C4H4INO2 The author mentioned the following in the article:

The most common type of modification of a phosphorus center is the replacement of one or two non-bridging atoms of the phosphate group with different heteroatoms (e.g., sulfur, selenium) or groups of atoms (e.g., Me, borane). Such compounds are referred to as the first generation of nucleotide analogs, e.g. I. We were interested in exploring the possibility of further functionalizing of the heteroatoms present in nucleoside phosphorothioates, phosphoroselenoate or boranephosphonates to create a second generation of nucleotide analogs with hopefully new biol. properties. Here we report a preliminary account of our work on introducing addnl. modifications on the sulfur or selenium heteroatom of nucleotide analogs.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Computed Properties of C4H4INO2) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Computed Properties of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Serpell, Christopher J.’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2021 | CAS: 626-02-8

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Name: 3-IodophenolHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Serpell, Christopher J.; Park, Ah Young; Robinson, Carol V.; Beer, Paul D. published an article in 2021. The article was titled 《Imidazolium-based catenane host for bromide recognition in aqueous media》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Name: 3-Iodophenol The information in the text is summarized as follows:

The synthesis of a novel catenated system which is dense in cationic hydrogen bonding imidazolium units is described. The interlocked host system displays a preference for binding of bromide over other halides, overcoming basicity and Hofmeister trends, under aqueous conditions. This is the first example of an imidazolium-based catenane acting as an anion host through C-H hydrogen bonding. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8Name: 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Name: 3-IodophenolHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Yan’s team published research in International Journal of Polymer Analysis and Characterization in 2019 | CAS: 1774-47-6

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Formula: C3H9IOS

Formula: C3H9IOSIn 2019 ,《Controlled synthesis of polymethylene-b-poly(ethylene glycol) as well as its crystallization and self-assembly behavior》 appeared in International Journal of Polymer Analysis and Characterization. The author of the article were Zhang, Yan; Zhou, Qihang; Liu, Yujian. The article conveys some information:

Polymethylene-b-poly(ethylene glycol) (PM-b-PEG) with different block length ratio was synthesized by a combination of polyhomologation and coupling reaction. The effect of hydrophilic and hydrophobic block length on the crystallization process and self-assembly behavior of PM-b-PEG was self-assembled were investigated. The results showed that with the increase of methylene units, the crystallization temperature of PM block raised from 54.59 °C to 70.93 °C gradually, while that of the PEG block reduced from 17.54 °C to 15.23 °C. In addition, the amphiphilic PM-b-PEG was self-assembled into star-like micelles in water, and its diameter extended from 98.2 nm to 151.9 nm as the block length of hydrophobic PM increased from 30 to 70. And the micelles also exhibit super stability when the concentration of copolymer precursor is 0.50 ∼ 0.90 mg/mL and the storage temperature lies in the range of 25 ∼ 60 °C. In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Formula: C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Formula: C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Itsukashi, Masako’s team published research in Journal of Photochemistry and Photobiology, A: Chemistry in 2018 | CAS: 624-73-7

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Recommanded Product: 624-73-7

In 2018,Itsukashi, Masako; Nakashima, Nobuaki; Yatsuhashi, Tomoyuki published 《Coulomb explosion of a series of α, ω-diiodoalkanes in intense laser fields》.Journal of Photochemistry and Photobiology, A: Chemistry published the findings.Recommanded Product: 624-73-7 The information in the text is summarized as follows:

The kinetic energy of ions produced by a Coulomb explosion, in which multiply charged mol. cations dissociate, is determined by the charge number, mass, and geometric configuration of the ions upon explosion. Although the importance of the structural deformation and migration of atoms on kinetic energy variations is well known, there has been little investigation into the effect of charge localization before the ions are released. In this study, the angular distributions of iodine and carbon ions ejected from linear alkanes, which have one iodine atom on each side of an alkyl chain having one to six carbon atoms, are measured. The highly charged iodine ions (I4+, I5+) are emitted mostly along the laser polarization direction, whereas the angular distribution of iodine ions becomes isotropic the longer the alkyl chain and the lower the charge number of iodines are. Furthermore, the longer the alkyl chain, the higher the kinetic energy of iodine and carbon ions. The emission of ions is discussed in terms of the selective ionization of aligned mols. based on their MOs. The charge localization during ionization in strong alternating elec. fields followed by two-body Coulomb explosion via a C-I bond cleavage is proposed. The experimental process involved the reaction of 1,2-Diiodoethane(cas: 624-73-7Recommanded Product: 624-73-7)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Recommanded Product: 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com