Tag: 200-300

《A new tricrystalline triblock terpolymer by combining polyhomologation and ring-opening polymerization. synthesis and thermal properties》 was written by Ladelta, Viko; Zapsas, George; Gnanou, Yves; Hadjichristidis, Nikos. Synthetic Route of C3H9IOSThis research focused ontricryst triblock terpolymer polyhomologation ring opening polymerization property. The article conveys some information:

New tricryst. triblock terpolymers, polyethylene-block-poly(ε-caprolactone)-block-poly(L-lactide) (PE-b-PCL-b-PLLA), were synthesized by ROP of ε-caprolactone (CL) and L-lactide (LLA) from linear ω-hydroxyl polyethylene (PE-OH) macroinitiators. The linear PE-OH macroinitiators were prepared by C1 polymerization of Me sulfoxonium methylide (polyhomologation). Tin(II) 2-ethylhexanoate was used as the catalyst for the sequential ROP of CL and LLA in one-pot polymerization at 85 °C in toluene (PE-OH macroinitiators are soluble in toluene at 80 °C). 1H NMR spectra confirmed the formation of PE-b-PCL-b-PLLA triblock terpolymers through the appearance of the characteristic proton peaks of each block. GPC traces showed the increase in the number average mol. weight from PE-OH macroinitiator to PE-b-PCL, and PE-b-PCL-b-PLLA corroborating the successful synthesis. The existence of three crystalline blocks was proved by DSC and XRD spectroscopy. The results came from multiple reactions, including the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Synthetic Route of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《(ZrO)2Fe2O5 as an efficient and recoverable nanocatalyst in C-C bond formation》 was written by Ghorbani-Choghamarani, Arash; Mohammadi, Masoud; Taherinia, Zahra. Application In Synthesis of 1-Iodo-4-methylbenzeneThis research focused onzirconium ferrite recoverable nanocatalyst carbon bond formation. The article conveys some information:

In this paper, the synthesis and characterization of zirconium ferrite ((ZrO)2Fe2O5) magnetic nanoparticles (MNPs) and their application as a catalyst in C-C cross-coupling reaction will be described. The structure of the catalyst was studied by Fourier transform IR spectroscopy (FT-IR), SEM, energy dispersive spectrometry (EDS), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), vibrating sample magnetometer (VSM) and ICP-OES anal. The resulting zirconium ferrite [(ZrO)2Fe2O5] was efficient for C-C coupling reactions, affording the desired products in good to excellent yields. Moreover, the catalyst could be easily recovered by magnetic separation and recycled for four times without significant loss of its catalytic activity. In the part of experimental materials, we found many familiar compounds, such as 1-Iodo-4-methylbenzene(cas: 624-31-7Application In Synthesis of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application In Synthesis of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Photooxygenation inhibits tau amyloid formation》 were Suzuki, Takanobu; Hori, Yukiko; Sawazaki, Taka; Shimizu, Yusuke; Nemoto, Yu; Taniguchi, Atsuhiko; Ozawa, Shuta; Sohma, Youhei; Kanai, Motomu; Tomita, Taisuke. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Tau amyloid formation and deposition are responsible for the onset of Alzheimer’s disease. In particular, the seeding activity of the tau protein plays an important role in the spreading of tau pathol. via its propagation in the human brain. Here we demonstrate that catalytic photo-oxygenation markedly suppresses tau seeding activity, resulting in the inhibition of amyloid formation, both in vitro and in cultured cells. In the part of experimental materials, we found many familiar compounds, such as 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2017,Chemical Communications (Cambridge, United Kingdom) included an article by Yang, Xinglin; Shan, Gang; Yang, Zimo; Huang, Guiyi; Dong, Guoqiang; Sheng, Chunquan; Rao, Yu. Related Products of 41252-95-3. The article was titled 《One-pot synthesis of quaternary carbon centered cyclobutanes via Pd(II)-catalyzed cascade C(sp3)-H activations》. The information in the text is summarized as follows:

A novel approach toward quaternary carbon centered cyclobutanes through Pd(II)-catalyzed sequential intramol. methylene C-H alkylation and intermol. methine C-H bond arylation, alkenylation, alkylation, alkynylation, allylation, benzylation or alkoxylation is described. These quaternary carbon centered cyclobutanes could be further diversified through Pd(II)-catalyzed γ-C(sp3)-H bond activations. The synthetic utility of this novel approach was exemplified by its application to the synthesis of a bioactive small mol. Thus, e.g., cascade intramol. C-H alkylation/C-H arylation of 6-bromohexanamide containing the 8-aminoquinoline directing group (I) with 4-iodoacetophenone in presence of Pd(OAc)2/Ag2CO3 afforded cyclobutane II (75% isolated). In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Related Products of 41252-95-3)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 41252-95-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C7H7IIn 2020 ,《Ligand-enabled gold-catalyzed 1,2-heteroarylation of alkenes》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Tathe, Akash G.; Chintawar, Chetan C.; Bhoyare, Vivek W.; Patil, Nitin T.. The article contains the following contents:

By adopting the interplay between ligand-enabled Au(I)/Au(III) catalysis and the unique π-activation mode of gold complexes, a highly coveted 1,2-heteroarylation of alkenes was accomplished. The present ligand-enabled approach not only circumvents the requirement for strong sacrificial oxidants or photocatalysts but also operates under mild reaction conditions by utilizing simple and non-prefunctionalized aryl coupling partners. In the experiment, the researchers used 1-Iodo-4-methylbenzene(cas: 624-31-7Computed Properties of C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Computed Properties of C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Recommanded Product: 4-Iodobenzoic acidIn 2019 ,《Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Lee, Chang Heon; Shim, Ha Eun; Song, Lee; Moon, Hi Gyu; Lee, Kyuhong; Yang, Jung Eun; Song, Ha Yeon; Choi, Yong Jun; Choi, Dae Seong; Jeon, Jongho. The article contains the following contents:

As a robust radioanal. method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-I-tagged pyrene analog. Single-photon emission computed tomog. and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity. The experimental process involved the reaction of 4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Recommanded Product: 4-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Quality Control of 3-IodophenolIn 2022 ,《Molecular engineering by σ-linkers enables delayed fluorescence emitters for high-efficiency sky-blue solution-processed OLEDs》 was published in Chemical Engineering Journal (Amsterdam, Netherlands). The article was written by Chen, Yanying; Li, Nengquan; Huang, Zhongyan; Xie, Guohua; Yang, Chuluo. The article contains the following contents:

Two novel thermally activated delayed fluorescence (TADF) emitters, Me2AcBO and F2AcBO, based on the 9,9-dimethylacridine donor and a rigid O-bridged cyclized B acceptor, were designed and synthesized for highly efficient blue solution-processed organic light-emitting diodes (OLEDs). Me2AcBO and F2AcBO feature a twin structure derived by coupling 2 individual TADF monomers through nonconjugated linkers. The 2 new emitters exhibit 3D mol. structures, excellent thermal/morphol. properties, high luminescence quantum yields >97%, and high reverse intersystem crossing rates ∼106 s-1, which greatly benefit the high device efficiency. Solution-processed sky-blue TADF OLEDs based on Me2AcBO and F2AcBO achieved the maximum external quantum efficiency of 11.0 and 10.9%, resp., with Commission Internationale de L’Eclairage (CIE) coordinates of (0.14, 0.25). Relatively low efficiency roll-offs of 33 and 34% at the luminance of 1000 cd/m2 were demonstrated for Me2AcBO and F2AcBO based devices, resp. This study presents a novel strategy to realize highly efficient sky-blue TADF emitters for solution-processed OLEDs. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8Quality Control of 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Quality Control of 3-Iodophenol Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthetic Route of C5H4INIn 2021 ,《Coupling of thiols and aromatic halides promoted by diboron derived super electron donors》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Franco, Mario; Vargas, Emily L.; Tortosa, Mariola; Cid, M. Belen. The article conveys some information:

Authors have proven that pyridine-boryl complexes can be used as superelectron donors to promote the coupling of thiols and aromatic halides through a SRN1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramol. electron transfer process. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Synthetic Route of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Synthetic Route of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Kittikhunnatham, Preecha; Leith, Gabrielle A.; Mathur, Abhijai; Naglic, Jennifer K.; Martin, Corey R.; Park, Kyoung Chul; McCullough, Katherine; Jayaweera, H. D. A. Chathumal; Corkill, Ryan E.; Lauterbach, Jochen; Karakalos, Stavros G.; Smith, Mark D.; Garashchuk, Sophya; Chen, Donna A.; Shustova, Natalia B. published an article in Angewandte Chemie, International Edition. The title of the article was 《A Metal-Organic Framework (MOF)-Based Multifunctional Cargo Vehicle for Reactive-Gas Delivery and Catalysis》.Category: iodides-buliding-blocks The author mentioned the following in the article:

The efficient delivery of reactive and toxic gaseous reagents to organic reactions was studied using metal-organic frameworks (MOFs). The simultaneous cargo vehicle and catalytic capabilities of several MOFs were probed for the first time using the examples of aromatization, aminocarbonylation and carbonylative Suzuki-Miyaura coupling reactions. These reactions highlight that MOFs served a dual role as a gas cargo vehicle and a catalyst, led to product formation with yields similar to reactions employing pure gases. Furthermore, the MOFs was recycled without sacrificing product yield, while simultaneously maintaining crystallinity. The reported findings were supported crystallog. and spectroscopically (e.g., diffuse reflectance IR Fourier transform spectroscopy), foreshadowing a pathway for the development of multifunctional MOF-based reagent-catalyst cargo vessels for reactive gas reagents as an attractive alternative to the use of toxic pure gases or gas generators. The results came from multiple reactions, including the reaction of 4-Chloro-2-iodoaniline(cas: 63069-48-7Category: iodides-buliding-blocks)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Bosch, Eric; Bowling, Nathan P. published an article in Acta Crystallographica, Section C: Structural Chemistry. The title of the article was 《Co-operative halogen bonds and nonconventional sp-C-H·O hydrogen bonds in 1:1 cocrystals formed between diethynylpyridines and N-halosuccinimides》.Product Details of 516-12-1 The author mentioned the following in the article:

The rapid evaporation of 1:1 solutions of diethynylpyridines and N-halosuccinimides, that react together to form haloalkynes, led to the isolation of unreacted 1:1 cocrystals of the two components. The 1:1 cocrystal formed between 2,6-diethynylpyridine and N-iodosuccinimide (C4H4INO2·C9H5N) contains an N-iodosuccinimide-pyridine I·N halogen bond and two terminal alkyne-succinimide carbonyl C-HO hydrogen bonds. The three-dimensional extended structure features interwoven double-stranded supramol. polymers that are interconnected through halogen bonds. The cocrystal formed between 3,5-diethynylpyridine and N-iodosuccinimide (C4H4INO2.C9H5N) also features an I·N halogen bond and two C-H·O hydrogen bonds. However, the components form essentially planar double-stranded one-dimensional zigzag supramol. polymers. The cocrystal formed between 3,5-diethynylpyridine and N-bromosuccinimide (C4H4BrNO2.C9H5N) is isomorphous to the cocrystal formed between 3,5-diethynylpyridine and N-iodosuccinimide, with a Br·N halogen bond instead of an I·N halogen bond. In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Product Details of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Product Details of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com