In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 96606-95-0, name is 3-(2-Iodophenyl)propanoic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. name: 3-(2-Iodophenyl)propanoic acid
1.50 g 3-(2-Iodophenyl)propanoic acid (5.43 mmol, 1 eq) were dissolved in 125 mL dry methanol, 1 mL 98% sulfuric acid (5.42 mmol, 1 eq) was added and the reaction mixture was stirred at rt for 21 h. The solvent was reduced in vacuo, ice water added to the residue and extracted thrice with diethyl ether. The combined organic phases were subsequently washed thrice with sat. sodium bicarbonate solution, twice with water and once with sat.sodium chloride solution, dried over MgSO4 and the solvent was removed in vacuo. Thereaction yielded 1.54 g of 2 (5.31 mmol, 98 %) as a colorless oil.
The synthetic route of 96606-95-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Wessig, Pablo; Pick, Charlotte; Schilde, Uwe; Tetrahedron Letters; vol. 52; 32; (2011); p. 4221 – 4223;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com