Category: 939759-26-9

Li, Yan published the artcileLigand-Controlled Cobalt-Catalyzed Regiodivergent Alkyne Hydroalkylation, Category: iodides-buliding-blocks, the main research area is alkyne haloalkane cobalt catalyst regioselective hydroalkylation; alkene preparation.

Herein, a ligand-controlled cobalt-catalyzed regiodivergent alkyne hydroalkylation was reported. The sensible selection of bisoxazoline and pyridine-oxazoline ligands led to reliable and predictable protocols that provided (E)-1,2-disubstituted and 1,1-disubstituted alkenes with high E/Z stereoselectivity and regioisomeric ratio starting from identical terminal alkyne and alkyl halide substrates and produced trisubstituted alkenes in the case of internal alkynes. This method exhibited a broad scope for terminal and internal alkynes with a wide range of activated and unactivated alkyl halides and shows excellent functional group compatibility.

Journal of the American Chemical Society published new progress about Addition reaction. 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Category: iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bauer, Gerald published the artcileCross-Coupling of Nonactivated Primary and Secondary Alkyl Halides with Aryl Grignard Reagents Catalyzed by Chiral Iron Pincer Complexes, SDS of cas: 939759-26-9, the main research area is cross coupling primary secondary alkyl halide aryl Grignard reagent; iron bisoxazolinylphenylamido pincer complex catalyzed coupling nonactivated alkyl halide; chiral iron pincer complex catalyzed coupling enantioselectivity.

Iron(III) bisoxazolinylphenylamido (bopa) pincer complexes are efficient precatalysts for the cross-coupling of nonactivated primary and secondary alkyl halides with Ph Grignard reagents. The reactions proceed at room temperature in moderate to excellent yields. A variety of functional groups can be tolerated. The enantioselectivity of the coupling of secondary alkyl halides is low.

Synthesis published new progress about Cross-coupling reaction. 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, SDS of cas: 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Davis, Tyler A. published the artcileChiral proton catalysis of secondary nitroalkane additions to azomethine: synthesis of a potent GlyT1 inhibitor, Recommanded Product: Benzyl 3-iodoazetidine-1-carboxylate, the main research area is enantioselective synthesis GlyT1 inhibitor aza Henry nitroazetidine amidine organocatalyst.

The first enantioselective synthesis of a potent GlyT1 inhibitor is described. A 3-nitroazetidine donor is used in an enantioselective aza-Henry reaction catalyzed by a bis(amidine)-triflic acid salt organocatalyst, delivering the key intermediate with 92% ee. This adduct is reductively denitrated and converted to the target through a short sequence, thereby allowing assignment of the absolute configuration of the more potent enantiomer.

Chemical Communications (Cambridge, United Kingdom) published new progress about Absolute configuration. 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Recommanded Product: Benzyl 3-iodoazetidine-1-carboxylate.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Zhen-Yu published the artcileTerminal C(sp3)-H alkylation of internal alkenes via Ni/H-catalyzed isomerization, HPLC of Formula: 939759-26-9, the main research area is internal alkene alkyl aryl halide terminal alkylation isomerization nickel.

An efficient nickel-catalyzed reductive relay cross-coupling of internal alkenes with alkyl (or aryl) halides has been developed. This method has demonstrated broad substrate scope, mild reaction conditions and excellent terminal-selectivity. Moreover, this efficient strategy could be applied to the terminal-selective alkylation of isomeric mixtures of internal alkenes.

Tetrahedron Letters published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, HPLC of Formula: 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Han published the artcileSynthesis of 2-Aryl Azetidines through Pd-Catalyzed Migration/Coupling of 3-Iodoazetidines and Aryl Boronic Acids, Application In Synthesis of 939759-26-9, the main research area is aryl azetidine preparation regioselective; iodoazetidine boronic acid migration cross coupling reaction palladium.

A palladium-catalyzed cross-coupling of 3-iodoazetidines and nonheteroaryl boronic acids was reported. The [1,1′-biphenyl]-2-yldicyclohexylphosphane ligand enabled the reaction that favored the formation of 2-aryl azetidines. The control experiments indicated that the reaction can proceed through either a palladium-hydride/dihydroazete complex or free dihydroazete intermediate followed by hydropalladation.

Organic Letters published new progress about Arylboronic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Application In Synthesis of 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lu, Xiao-Yu published the artcileTrisubstituted olefin synthesis via Ni-catalyzed hydroalkylation of internal alkynes with non-activated alkyl halides, Formula: C11H12INO2, the main research area is alkene preparation stereoselective regioselective; internal alkyne alkyl halide nickel catalyst hydroalkylation.

Ni-catalyzed regio- and stereo-selective hydroalkylation of internal alkynes R1CCR2 [R1 = Ph, pyridin-3-yl, (CH2)2CH3, etc.; R2 = Me, Ph, (CH2)3CH3, etc.] with non-activated alkyl halides XR3 (R3 = cyclohexyl, butan-2-yl, 1-[(4-methylbenzene)sulfonyl]pyrrolidin-3-yl, etc.; X = I, Br) was reported. This method does not use any sensitive organometallic reagents and shows good functional group compatibility, which enables the efficient synthesis of many tri-substituted olefins R1CH=C(R2)(R3) from readily available coupling partners. It also provides a straightforward method for the modification of bioactive organic mols.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Formula: C11H12INO2.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Zhenwei published the artcilePalladium-Catalyzed Hiyama Cross-Couplings of Arylsilanes with 3-Iodoazetidine: Synthesis of 3-Arylazetidines, Application In Synthesis of 939759-26-9, the main research area is arylazetidine preparation palladium catalyzed Hiyama cross coupling; cross coupling arylsilane iodoazetidine.

The first palladium-catalyzed Hiyama cross-coupling reactions of arylsilanes with 3-iodoazetidine were described. The protocol provides a convenient access to a variety of useful 3-arylazetidines which are of great interest in pharmaceutical laboratories in moderate to good yields (30%-88%). In addition, this strategy has the advantage of easy operation and mild reaction conditions.

Journal of Organic Chemistry published new progress about Aryl silanes Role: RCT (Reactant), RACT (Reactant or Reagent). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Application In Synthesis of 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cheung, Chi Wai published the artcileMild and Phosphine-Free Iron-Catalyzed Cross-Coupling of Nonactivated Secondary Alkyl Halides with Alkynyl Grignard Reagents, Computed Properties of 939759-26-9, the main research area is secondary alkyl halide alkynyl Grignard iron cross coupling catalyst; alkyne substituted preparation.

A simple protocol for iron-catalyzed cross-coupling of nonactivated secondary alkyl bromides and iodides with alkynyl Grignard reagents at room temperature has been developed. A wide range of secondary alkyl halides and terminal alkynes are tolerated to afford the substituted alkynes in good yields. A slight modification of the reaction protocol also allows for cross-coupling with a variety of primary alkyl halides.

Organic Letters published new progress about Alkynes, internal Role: SPN (Synthetic Preparation), PREP (Preparation). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Computed Properties of 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lu, Xi published the artcilePractical carbon-carbon bond formation from olefins through nickel-catalyzed reductive olefin hydrocarbonation, Application In Synthesis of 939759-26-9, the main research area is carbon bond formation nickel catalyst chemoselective regioselective olefin hydrocarbonation.

A general process for the intermol. reductive coupling of unactivated olefins with alkyl or aryl electrophiles under the promotion of a simple nickel catalyst system was reported. This new reaction presented a conceptually unique and practical strategy for the construction of C(sp2)-C(sp3) and C(sp3)-C(sp3) bonds without using any organometallic reagent. The reductive olefin hydrocarbonation also exhibited excellent compatibility with varieties of synthetically important functional groups and therefore, provided a straightforward approach for modification of complex organic mols. containing olefin groups.

Nature Communications published new progress about C-C bond formation. 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Application In Synthesis of 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Qiu, Zhenjiang published the artcileRegioselective α-benzylation of 3-iodoazetidines via Suzuki cross-coupling, Computed Properties of 939759-26-9, the main research area is benzyl azetidine preparation regioselective; iodoazetidine benzylboronic acid pinacol ester benzylation Suzuki palladium catalyst.

An efficient protocol for the synthesis of α-benzyl azetidines I [R = 4-F3COC6H4, 2-F-C6H4, naphthalen-2-yl, etc.; R1 = C(O)OCH2C6H5, C(O)OC(CH3)3] starting from benzylboronic acid pinacol ester derivatives II and 3-iodoazetidine III was developed. A wide range of α-benzyl azetidine derivatives I was obtained in moderate to good yields with high regioselectivity (>99%).

Tetrahedron Letters published new progress about Benzylation catalysts (regioselective). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Computed Properties of 939759-26-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com