Category: 88105-22-0

Satonaka, Hajime; Abe, Kazuhisa; Hirota, Minoru published the artcile< Carbon-13 NMR spectra of substituted 2-thiophenecarboxylic acid methyl esters and MNDO calculations>, Electric Literature of 88105-22-0, the main research area is NMR methyl thiophenecarboxylate; MNDO methyl thiophenecarboxylate; conformation methyl thiophenecarboxylate.

The 13C NMR spectra have been reported on substituted 2-thiophenecarboxylic acid Me esters. The chem. shift of ring carbons in Me 4- and 5-substituted 2-thiophenecarboxylates was correlated linearly with that of the corresponding carbons in substituted thiophenes. Plots of the 13C-H coupling constants also showed a good linear relation. The 13C NMR data were interpreted by the stable conformation and percent s character of C-H bonds obtained by MNDO calculation

Bulletin of the Chemical Society of Japan published new progress about Electron configuration. 88105-22-0 belongs to class iodides-buliding-blocks, and the molecular formula is C6H5IO2S, Electric Literature of 88105-22-0.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Biller, Scott A.; Abt, Jeffrey W.; Pudzianowski, Andrew T.; Rich, Lois C.; Slusarchyk, Dorothy A.; Ciosek, Carl P. Jr. published the artcile< Aromatic isosteres as conformational probes for an isoprenyl subunit: application to inhibitors of squalene synthase>, Related Products of 88105-22-0, the main research area is aromatic isotere squalene synthase inhibitor; isoprenyl subunit conformational probe.

A series of aromatic isosteres of the farnesyl chain of potent squalene synthase inhibitor I were prepared and evaluated. The results are consistent with the local conformation indicated in structure II.

Bioorganic & Medicinal Chemistry Letters published new progress about Stereoselective synthesis. 88105-22-0 belongs to class iodides-buliding-blocks, and the molecular formula is C6H5IO2S, Related Products of 88105-22-0.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Satonaka, Hajime published the artcile< The substituent effects in thiophene compounds. I. Proton NMR and IR studies in methyl (substituted 2-thiophenecarboxylates)>, Synthetic Route of 88105-22-0, the main research area is LFER electronegativity IR thiophenecarboxylate; carbonyl group IR thiophenecarboxylate; proton NMR thiophenecarboxylate; spin coupling thiophenecarboxylate.

The 1H NMR and the IR CO group stretching frequencies of Me (3-, 4-, and 5-substituted 2-thiophenecarboxylate)s are observed Good linear correlations between the chem. shifts of the ring protons in Me (4- and 5-substituted 2-thiophenecarboxylate)s and those of the corresponding protons in substituted thiophenes were observed The coupling constants in Me (substituted 2-thiophenecarboxylate)s gave good correlations against the corresponding ones in substituted thiophenes. The IR carbonyl stretching frequencies in Me (5-substituted 2-thiophenecarboxylate)s were correlated reasonably well with the chem. shifts of 5-protons in 2-substituted thiophenes. The coupling constants in Me 2-thiophenecarboxylate series varied linearly with the electronegativities of the substituents.

Bulletin of the Chemical Society of Japan published new progress about Carbonyl group. 88105-22-0 belongs to class iodides-buliding-blocks, and the molecular formula is C6H5IO2S, Synthetic Route of 88105-22-0.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

D’Agostini, Agnese; D’Auria, Maurizio published the artcile< Photochemical coupling between halogenoheterocyclic and heterocyclic derivatives>, COA of Formula: C6H5IO2S, the main research area is photochem coupling aryl aryl haloheterocycle heterocycle; iodothiophene iodofuran photochem coupling acetoxyallylthiophene acetoxyallylfuran.

The photochem. reaction between 5-iodo-heteroaryl derivatives I (X = O, R = H; X = S, R = Me, H, OMe) and both 3-heteroaryl allylic alcs. II (Y = O, S, R1 = H) and acetates II (Y = O, S, R1 = Ac) have been investigated. The presence of an alc. function was not compatible with photochem. coupling since compounds I were photoreduced in the presence of an alc. In contrast, the acetates gave the expected coupling products III (same X, Y, R, mixture of E and Z isomers). The presence of a weak electron-withdrawing group on the alkene induced an inverted regiochem. giving only aryl-aryl coupling products. The same behavior was observed using 2-(3-acetoxyprop-1-ynyl)thiophene, in which case only the product derived from aryl-aryl coupling was again observed When 2-prop-1-ynylthiophene was used as starting material, the product resulting from attack on the Me group was also observed Photochem. coupling between 2-thienylacetonitrile and halothienyl derivatives I (X = S, R = Me, H) gave no reaction product. In contrast, the irradiation of Me 2-thienylacetate and Me 2-(2-thienyl)propionate in the presence of I (X = S, R = Me, H) did give the corresponding aryl-aryl coupling products.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Photochemical coupling reaction. 88105-22-0 belongs to class iodides-buliding-blocks, and the molecular formula is C6H5IO2S, COA of Formula: C6H5IO2S.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com