Gaikwad, Mahadev’s team published research in Chemistry & Biology Interface in 2022 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Formula: C7H5IO2 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Formula: C7H5IO2In 2022 ,《Synthesis, characterization and anti-microbial screening of novel substituted thiadiazole-5-aminotetrazoles》 was published in Chemistry & Biology Interface. The article was written by Gaikwad, Mahadev; Gorepatil, Amarsinha; Gorepatil, Pratapsinha; Kadam, Vishal; Gaikwad, Shivshankar; Shinde, Vishnu; Ingle, Vilas. The article contains the following contents:

An efficient and green synthesis of substituted thiadiazole-5-aminotetrazoles I [R = Ph, benzyl, cinnamyl, etc.] were prepared in-situ by reaction of cyanogen bromide and sodium azide to generate a cyanogen azide as an intermediate in acetonitrile. The cyclization reaction of cyanogen azide and substituted thiadiazoles containing primary amines in acetonitrile-water solvent media, gave the intermediate 1-substituted 5-aminotetrazoles in good yield. In addition, to further evaluate the role of synthesized mols. for antimicrobial activities, and it’s found that compound I [R = 4-O2NC6H4, 2-IC6H4] showed a good antimicrobial for broad range of bacterial and fungal pathogens. After reading the article, we found that the author used 2-Iodobenzoic acid(cas: 88-67-5Formula: C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Formula: C7H5IO2 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Stivanin, Mateus L.’s team published research in Organic Chemistry Frontiers in 2022 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.COA of Formula: C7H5IO2

In 2022,Stivanin, Mateus L.; Gallo, Rafael D. C.; Spadeto, Joao Paulo M.; Cormanich, Rodrigo A.; Jurberg, Igor D. published an article in Organic Chemistry Frontiers. The title of the article was 《A visible light-mediated three-component strategy based on the ring-opening of cyclic ethers with aryldiazoacetates and nucleophiles》.COA of Formula: C7H5IO2 The author mentioned the following in the article:

A blue light-promoted reaction between aryldiazoacetates 4-R1C6H4C(=N2)C(O)2R2 (R1 = F, Cl, CF3, etc.; R2 = Me, t-Bu, Bn, propargyl) and different nucleophiles, e.g., benzoic acid has been developed in the presence of THF (and other cyclic ethers like THP, 1,4-dioxane, and 1,4,7,10,13,16-hexaoxacyclooctadecane) as the solvent, allowing the incorporation of these three elements into a single products, e.g., I. Formally, this transformation represents an O-H insertion strategy of more complex alcs. into aryldiazoesters without the need of pre-assembling them. The method is mild and efficient and proceeds in the absence of metals, generally at room temperature After reading the article, we found that the author used 2-Iodobenzoic acid(cas: 88-67-5COA of Formula: C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.COA of Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhong, Xianqiang’s team published research in Advanced Synthesis & Catalysis in 2021 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Safety of 2-Iodobenzoic acid

Zhong, Xianqiang; Luo, Jianghao; Zhou, Wei; Cai, Qian published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《A Synthesis of Spirooxindole-Isoindolinones Through Ugi Reaction Followed by Copper-Catalyzed Tandem C-N/C-C Coupling Process》.Safety of 2-Iodobenzoic acid The article contains the following contents:

A synthesis of spiroindolinone-isoindolinone skeletons was presented. The protocol was through a Ugi four-component reaction followed by highly efficient and mild copper-catalyzed intramol. tandem C-N/C-C coupling process. Control experiments demonstrated that the formation of C-C bond was a copper catalyzed coupling process rather than base promoted nucleophilic aromatic substitution pathway which proposed in Prof. Van der Eycken’s palladium catalyst system previously. In the part of experimental materials, we found many familiar compounds, such as 2-Iodobenzoic acid(cas: 88-67-5Safety of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Safety of 2-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sahoo, Ashish Kumar’s team published research in Journal of Organic Chemistry in 2021 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

《Visible-Light-Mediated Difunctionalization of Alkynes: Synthesis of β-Substituted Vinylsulfones Using O- and S-Centered Nucleophiles》 was written by Sahoo, Ashish Kumar; Dahiya, Anjali; Das, Bubul; Behera, Ahalya; Patel, Bhisma K.. SDS of cas: 88-67-5This research focused onvinyl sulfone preparation regioselective diastereoselective green chem; alkyne sulfinate nucleophile sulfonylation photocatalyst. The article conveys some information:

A series of Z-β-substituted vinylsulfones (Z)-R1C(R3C(O)O)=CHS(O)2R2 (R1 = Ph, cyclohexyl, 4-bromophenyl, etc.; R2 = Me, 4-methylphenyl, thiophen-2-yl, etc.; R3 = acetyl, stearyl, cyclopropylmethyl, etc.) (I) was prepared via a green-light-induced, regioselective difunctionalization of terminal alkyne R1C6H4CCH has been disclosed using sodium arylsulfinates R2S(O)2Na and carboxylic acids R3C(O)OH in the presence of eosin Y as the photocatalyst. The present methodol. is further demonstrated by employing NH4SCN as S-centered nucleophile instead of carboxylic acid. The mechanistic investigation reveals a radical-induced iodosulfonylation followed by a base-mediated nucleophilic substitution. The mechanism is supported by various studies viz., radical-trapping experiment, fluorescence quenching and CV studies. In this protocol, Z-β-substituted vinylsulfones (I) and (Z)-R4C6H4C(R5)=C(R6)S(O)2R7 (R4 = H, 3-Me, 4-Me, 4-tert-butyl; R5 = I, SCN; R6 = H, methyl; R7 = Ph, 4-methylphenyl) are obtained exclusively covering a broad range of alkynes and nucleophiles which are often unaddressed. The present strategy can tolerate structurally discrete substrates with steric bulk and different electronic properties, which provides a straightforward and practical pathway for the synthesis of highly functionalized Z-β-substituted vinylsulfones. Herein, C-O and C-S bonds are assembled simultaneously with the concomitant introduction of important functional groups viz. ester, thiocyanate, and sulfone. The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5SDS of cas: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhou, Shiqing’s team published research in Environmental Science & Technology in 2019 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 88-67-5

《Oxidation Mechanisms of the UV/Free Chlorine Process: Kinetic Modeling and Quantitative Structure Activity Relationships》 was written by Zhou, Shiqing; Zhang, Weiqiu; Sun, Julong; Zhu, Shumin; Li, Ke; Meng, Xiaoyang; Luo, Jinming; Shi, Zhou; Zhou, Dandan; Crittenden, John C.. Product Details of 88-67-5This research focused onwastewater oxidation UV chlorine kinetics model. The article conveys some information:

Recently, the UV/free chlorine process has gained attention as a promising technol. for destroying refractory organic contaminants in the aqueous phase. We have developed a kinetic model based on first-principles to describe the kinetics and mechanisms of the oxidation of organic contaminants in the UV/free chlorine process. Substituted benzoic acid compounds (SBACs) were chosen as the target parent contaminants. We determined the second-order rate constants between SBACs and reactive chlorine species (RCS; including Cl·, Cl-2· and ClO·) by fitting our model to the exptl. results. We then predicted the concentration profiles of SBACs under various operational conditions. We analyzed the kinetic data and predicted concentration profiles of reactive radicals (HO· and RCS), we found that ClO· was the dominant radicals for SBACs destruction. In addition, we established quant. structure activity relationships (QSARs) that can help predict the second-order rate constants for SBACs destruction by each type of reactive radicals using SBACs Hammett constants Our first-principles-based kinetic model has been verified using exptl. data. Our model can facilitate a design for the most cost-effective application of the UV/free chlorine process. For example, our model can determine the optimum chlorine dosage and UV light intensity that result in the lowest energy consumption. The experimental part of the paper was very detailed, including the reaction process of 2-Iodobenzoic acid(cas: 88-67-5Product Details of 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Thorat, Vijaykumar H.’s team published research in Organic Chemistry Frontiers in 2021 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5

Thorat, Vijaykumar H.; Aman, Hasil; Tsai, Yu-Lin; Pallikonda, Gangaram; Chuang, Gary Jing; Hsieh, Jen-Chieh published an article in 2021. The article was titled 《Cobalt-catalyzed coupling reactions of 2-halobenzamides with alkynes: investigation of ligand-controlled dual pathways》, and you may find the article in Organic Chemistry Frontiers.SDS of cas: 88-67-5 The information in the text is summarized as follows:

The Co-catalyzed reactions of 2-halobenzamides and alkynes to form isoquinolones or 2-vinyl benzamides were described here. The formation of the two selective products was fully controlled by adopted ligands. A study of the mechanism demonstrated that these two reactions proceed through different pathways. The radical process and the two-electron transfer activation of the C-X bond were resp. proposed for these two reactions. In the experimental materials used by the author, we found 2-Iodobenzoic acid(cas: 88-67-5SDS of cas: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Voutyritsa, Errika’s team published research in Chemistry – A European Journal in 2020 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. COA of Formula: C7H5IO2 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

《Photochemical Functionalization of Heterocycles with EBX Reagents: C-H Alkynylation versus Deconstructive Ring Cleavage》 was published in Chemistry – A European Journal in 2020. These research results belong to Voutyritsa, Errika; Garreau, Marion; Kokotou, Maroula G.; Triandafillidi, Ierasia; Waser, Jerome; Kokotos, Christoforos G.. COA of Formula: C7H5IO2 The article mentions the following:

Herein, a cheap and efficient photochem. method for the C-H functionalization of saturated O-heterocycles, as well as the deconstructive ring-cleavage of S-heterocycles, employing hypervalent iodine alkynylation reagents (ethynylbenziodoxolones, EBX) were reported. This photochem. alkynylation was performed utilizing phenylglyoxylic acid as the photoinitiator, leading to the corresponding products in good to high yields, under household fluorescent light bulb irradiation When O-heterocycles were employed, the expected α-C-H alkynylation took place. In contrast, oxidative ring-opening to form a thioalkyne and an aldehyde was observed with S-heterocycles. Preliminary mechanistic experiments were presented to give first insights into this puzzling divergent reactivity. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5COA of Formula: C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. COA of Formula: C7H5IO2 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Usami, Kaoru’s team published research in European Journal of Organic Chemistry in 2020 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Quality Control of 2-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

《Transition-Metal-Free Synthesis of Phenanthridinones through Visible-Light-Driven Oxidative C-H Amidation》 was written by Usami, Kaoru; Yamaguchi, Eiji; Tada, Norihiro; Itoh, Akichika. Quality Control of 2-Iodobenzoic acid And the article was included in European Journal of Organic Chemistry in 2020. The article conveys some information:

The treatment of N-aryl biphenylcarboxamide 2-(4-R2C6H4)-4-R1C6H3C(O)NHR (R = Me, Ph, 1,3-benzothiazol-2-yl, etc.; R1 = H, Br, phenyl; R2 = H, OMe, tert-Bu, Ph, trifluoromethyl, Cl), 1-chloroanthraquinone (1-Cl-AQN) catalyst, and K2CO3 in CHCl3 under visible light irradiation affords phenanthridinone I via radical cyclization. This reaction proceeds under transition-metal-free condition, room temperature, and direct C-H amidation. Mechanistic studies indicate that amidyl radical generation proceeds by visible light induced proton coupled electron transfer (PCET) from N-H bond of the amide. The results came from multiple reactions, including the reaction of 2-Iodobenzoic acid(cas: 88-67-5Quality Control of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Quality Control of 2-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Amos, Stephanie G. E.’s team published research in Journal of Organic Chemistry in 2019 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Product Details of 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

The author of 《Metal-Free Electrophilic Alkynylation of Sulfenate Anions with Ethynylbenziodoxolone Reagents》 were Amos, Stephanie G. E.; Nicolai, Stefano; Gagnebin, Alec; Le Vaillant, Franck; Waser, Jerome. And the article was published in Journal of Organic Chemistry in 2019. Product Details of 88-67-5 The author mentioned the following in the article:

Alkynyl sulfoxides are important building blocks with a unique reactivity in organic chem., but only a few reliable methods have been reported to synthesize them. A novel route to access alkynyl sulfoxides is reported herein by using ethynyl benziodoxolone (EBX) reagents to trap sulfenate anions generated in situ, via a retro-Michael reaction. The reaction takes place under metal-free and mild conditions. It is compatible with aryl, heteroaryl, and alkyl sulfoxides with up to 90% yield. This practical access to alkynyl sulfoxides is expected to facilitate the application of these useful building blocks in organic synthesis. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5Product Details of 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Product Details of 88-67-5Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Das, Krishna Mohan’s team published research in Organic & Biomolecular Chemistry in 2022 | CAS: 88-67-5

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.HPLC of Formula: 88-67-5

Das, Krishna Mohan; Pal, Adwitiya; Adarsh, Nayarassery N.; Thakur, Arunabha published an article in 2022. The article was titled 《A novel quinoline-based NNN-pincer Cu(II) complex as a superior catalyst for oxidative esterification of allylic C(sp3)-H bonds》, and you may find the article in Organic & Biomolecular Chemistry.HPLC of Formula: 88-67-5 The information in the text is summarized as follows:

A quinoline-based NNN-pincer Cu(II) complex acts as an air stable superior catalyst for the oxidative cross-coupling of the allyl sp3 C-H bond with an acid for the synthesis of allyl esters in a homogeneous system at ambient temperature The synthesized catalyst, Cu(II) complex has been well characterized by various anal. techniques (HRMS, single crystal X-ray diffraction, CV, EPR, UV-vis spectroscopy) and showed excellent catalytic activity for the oxidative esterification of allylic C(sp3)-H bonds at 40°C within a very short period of time (1 h) using only 1 mol% of the catalyst. A wide variety of aromatic allylic esters were synthesized in moderate to good yields, which could be extended to aliphatic allyl esters as well. The results came from multiple reactions, including the reaction of 2-Iodobenzoic acid(cas: 88-67-5HPLC of Formula: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.HPLC of Formula: 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com