Category: 88-67-5

The author of 《Iodophenylsulfonates and iodobenzoates as redox-active supporting electrolytes for electrosynthesis》 were Roesel, Arend F.; Broese, Timo; Majek, Michal; Francke, Robert. And the article was published in ChemElectroChem in 2019. Formula: C7H5IO2 The author mentioned the following in the article:

Hypervalent iodine compounds constitute a popular class of reagents in organic chem. Regardless of whether they are generated in situ from an iodoarene precursor with a terminal oxidant or used in stoichiometric amounts, the resulting separation and waste issues are major challenges en route to sustainable and scalable processes. The electrochem. generation of iodine(III) compounds represents an attractive alternative, since elec. current is used as traceless oxidant and unstable or hazardous species are conveniently generated in situ. In this context, we have explored the possibility for the use of iodoarene sulfonates and iodobenzoates as ex-cell mediators for electrosynthesis in 1,1,1,3,3,3-hexafluoroisopropanol. While 2-, 3- and 4-iodobenzoate salts proved to be impractical for various reasons, 2- and 4-iodobenzenesulfonates salts can be selectively oxidized to the iodine(III) species and used for synthetic applications. The ionic tag on the mediator allows for electrolysis without supporting electrolyte additives and enables a straightforward recovery from the product mixture The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Formula: C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Chemical Science included an article by Caramenti, Paola; Declas, Nina; Tessier, Romain; Wodrich, Matthew D.; Waser, Jerome. Recommanded Product: 2-Iodobenzoic acid. The article was titled 《Stereoselective synthesis of alkyl-, aryl-, vinyl- and alkynyl-substituted Z-enamides and enol ethers》. The information in the text is summarized as follows:

Enamides and enol ethers are valuable building blocks in synthetic chem., yet their stereoselective synthesis can be challenging. Herein, authors report a new stereoselective synthesis of vinyl, aryl, alkynyl, alkyl and thio-substituted Z-enamides and enol ethers based on the use of vinylbenziodoxolone (VBX) reagents. The stable VBX reagents were synthesized by stereoselective addition of N- or O-nucleophiles on the corresponding alkynyl reagents in the presence of a catalytic amount of cesium carbonate. The VBX reagents were used in palladium-catalyzed cross-couplings at room temperature to access Z-enamides and enol ethers. After reading the article, we found that the author used 2-Iodobenzoic acid(cas: 88-67-5Recommanded Product: 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Recommanded Product: 2-Iodobenzoic acid In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Wang, Chang-Sheng; Tan, Ploypailin Siew Ling; Ding, Wei; Ito, Shingo; Yoshikai, Naohiko published an article in Organic Letters. The title of the article was 《Regio- and Stereoselective Synthesis of Enol Carboxylate, Phosphate, and Sulfonate Esters via Iodo(III)functionalization of Alkynes》.Recommanded Product: 88-67-5 The author mentioned the following in the article:

Synthesis of β-Iodo(III)enol carboxylates, I (R1 = Et, Me, Bu, t-Bu; R2 = Et, Ph, thiophen-2-yl, etc.; R3 = 4-oxopentanoyl, benzoyl, 2,2-dimethylpropyl, etc.) phosphates, I (R3 = diethoxyphosphoroso, diphenoxyphosphoroso, dimethoxyphosphoroso, diphenylphosphoroso) and tosylates I (R3 = Ts) can be efficiently performed through regio- and stereoselective iodo(III)functionalization of alkynes R1CCR2. The combination of 1,2-benziodoxole, 1-chloro-1,3-dihydro-3,3-bis(trifluoromethyl)- and silver salt has proven to generate a versatile cationic iodine(III) electrophile to activate alkynes and engage various carboxylic acids R4COOH (R4 = Me, Ph, 2-phenylethenyl, etc.), tri-Et phosphate and p-toluenesulfonic acid as nucleophiles. The β-iodo(III)enol esters serve as starting materials for the synthesis of multisubstituted alkenes I through sequential cross-coupling of the C-I(III) and C-O bonds. In the experimental materials used by the author, we found 2-Iodobenzoic acid(cas: 88-67-5Recommanded Product: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Recommanded Product: 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Marchese, Austin D.; Adrianov, Timur; Kollen, Martin F.; Mirabi, Bijan; Lautens, Mark published an article in 2021. The article was titled 《Synthesis of Carbocyclic Compounds via a Nickel-Catalyzed Carboiodination Reaction》, and you may find the article in ACS Catalysis.Computed Properties of C7H5IO2 The information in the text is summarized as follows:

A scalable nickel-catalyzed carboiodination reaction generating 6-membered carbocycles I [R1 = H, 7-Me, 5-F, etc.; R2 = Me, n-Pr, Bn; R3 = CO2Me, CO2Et, CO2t-Bu, CO2Ph; R4 = CO2Me, CO2Et, CO2t-Bu, CO2Ph] was reported. NiI2 and P(OEt)3 as the ligand and reducing agent, provided decorated iodomethyl-tetrahydronaphthalenes I in up to 94% yield. The impact of varying electronic and steric parameters on the reaction were reported and a nonlinear Hammett plot was obtained, supporting a change in rate-determining step from oxidative addition to reductive elimination. Exptl. and DFT studies suggested the malonate group might stabilize a nickel oxidative-addition complex. A variety of heteroatom-containing nucleophiles and medicinally relevant heterocycles were easily incorporated into the products via simple SN2 chem. In addition to this study using 2-Iodobenzoic acid, there are many other studies that have used 2-Iodobenzoic acid(cas: 88-67-5Computed Properties of C7H5IO2) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Computed Properties of C7H5IO2 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Gold-Catalyzed 1,2-Oxyalkynylation of N-Allenamides with Ethylnylbenziodoxolones》 were Banerjee, Somsuvra; Senthilkumar, Beeran; Patil, Nitin T.. And the article was published in Organic Letters in 2019. Recommanded Product: 88-67-5 The author mentioned the following in the article:

A gold-catalyzed 1,2-oxyalkynylation of N-allenamides with ethylnylbenziodoxolones (EBXs) has been achieved for the first time. The reaction, which follows a redox-neutral Au(I)/Au(III) catalytic pathway, was enabled in an attempt to exhaust the EBX reagents atom-economically by putting the nucleophilic carboxylate part of EBXs to appropriate use. This constitutes the first example for gold-catalyzed β-alkynylation of N-allenamides to construct highly valuable 1,3-enynes. The potential of the sequence is further documented by some follow-up transformations. In addition to this study using 2-Iodobenzoic acid, there are many other studies that have used 2-Iodobenzoic acid(cas: 88-67-5Recommanded Product: 88-67-5) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Recommanded Product: 88-67-5 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex》 were Yudasaka, Masaharu; Shimbo, Daisuke; Maruyama, Toshifumi; Tada, Norihiro; Itoh, Akichika. And the article was published in Organic Letters in 2019. Application of 88-67-5 The author mentioned the following in the article:

The synthesis of a crystalline ethynyl-1,2-benziodoxol-3(1H)-one (EBX)-acetonitrile complex is described. EBX has been widely used as an active species for a variety of reactions; however, its high instability has so far prevented its isolation. The EBX-acetonitrile is self-assembled into a double-layered honeycomb structure through weak hypervalent iodine secondary interactions and hydrogen bonding. The N-ethynylation of a variety of sulfonamides using the EBX-acetonitrile complex as a substrate under mild conditions is also described.2-Iodobenzoic acid(cas: 88-67-5Application of 88-67-5) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Application of 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Ren, Jing; Jia, Meng-Cheng; Du, Feng-Huan; Zhang, Chi published an article in Chinese Chemical Letters. The title of the article was 《A general method for one-step synthesis of monofluoroiodane(III) reagents using silver difluoride》.Safety of 2-Iodobenzoic acid The author mentioned the following in the article:

A new general method for one-step synthesis of four kinds of fluoroiodane(III) reagents by treating the corresponding aryl iodides with silver difluoride (AgF2) was reported. This is the first method applicable for the synthesis of all four fluoroiodane(III) reagents including p-iodotoluene difluoride, fluoro-benziodoxoles, fluoro-benziodoxolones and fluoro-N-acetylbenziodazole. AgF2 was firstly employed in the direct oxidative fluorination of iodobenzene and thus has shown its outstanding oxidation and fluorine-transfer ability. The use of AgF2 has improved the synthesis of fluoroiodane(III) reagents by shortening the reaction steps, avoiding the use of hazardous reagents and simplifying the exptl. operations. It was worth noting that the developed first one-step direct synthetic method for fluoro-benziodoxolones, while fluoro-benziodoxolones can only be synthesized through Cl→F ligand exchange reaction previously. In the experimental materials used by the author, we found 2-Iodobenzoic acid(cas: 88-67-5Safety of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Safety of 2-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Kumar, Rajesh; Sayala, Kapil Dev; Tang, Houliang; Tsarevsky, Nicolay V. published an article in Polymer International. The title of the article was 《Hypervalent iodine-based initiators and efficient chain transfer agents for the synthesis of branched polymers from crosslinkers》.Quality Control of 2-Iodobenzoic acid The author mentioned the following in the article:

The synthesis of hyperbranched polymers with alkyl chloride-type chain ends was accomplished by the copolymerization of Me methacrylate and a crosslinker, ethylene glycol dimethacrylate, in the presence of 1-chloro-1,2-benziodoxol-3(1H)-one (BIO-Cl), which served as both a radical initiator and an efficient chain transfer agent. The polymerizations were carried out under thermal (80°C) and photochem. (irradiation with visible light) conditions. As a result of the transfer of Cl atoms from BIO-Cl to the propagating radicals, gelation was delayed to high monomer conversions and, until that point, soluble branched polymers were formed. Even pure crosslinker could be polymerized to moderate conversions (>15%, depending on the amount of added BIO-Cl), yielding branched polymers prior to formation of networks. The effect of the concentrations of crosslinker and hypervalent iodine(III) compound on the outcome of the (co)polymerizations as well as the kinetic features of Cl transfer and decomposition of BIO-Cl were studied in detail. 2022 Society of Industrial Chem. The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Quality Control of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Quality Control of 2-Iodobenzoic acidHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Marchese, Austin D.; Mirabi, Bijan; Johnson, Colton E.; Lautens, Mark published an article in Nature Chemistry. The title of the article was 《Reversible C-C bond formation using palladium catalysis》.Name: 2-Iodobenzoic acid The author mentioned the following in the article:

The development of palladium- and nickel-catalyzed carboiodination reactions afforded access to the cis and trans diastereomers of the iodo-dihydroisoquinolone products. Using these substrates, an extensive study investigating the reversibility of C-C bond formation using a simple palladium catalyst was undertaken. Herein, the authors report a comprehensive investigation of reversible C-C bond formation using palladium catalysis employing diastereomeric neopentyl iodides as the starting point. It was shown that both diastereomers could be converted to a common product under identical catalytic conditions. A combination of exptl. and computational studies were used to probe the operative mechanism. Several concepts key to understanding the process of reversible C-C bond formations were investigated, including the effect of electronic and steric parameters on the C-C bond-cleavage step. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5Name: 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Name: 2-Iodobenzoic acid In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zu, Bing; Ke, Jie; Guo, Yonghong; He, Chuan published their research in Chinese Journal of Chemistry in 2021. The article was titled 《Synthesis Of Diverse Aryliodine(III) Reagents By Anodic Oxidation》.Reference of 2-Iodobenzoic acid The article contains the following contents:

An anodic oxidation enabled synthesis of hypervalent iodine(III) reagents from aryl iodides is demonstrated. Under mild electrochem. conditions, a range of aryliodine(III) reagents, including iodosylarenes, e.g., PhI(OAc)2, (difunctional-iodo)arenes, e.g., PhI(OH){OP(O)Ph2}, diaryliodonium salts, e.g., I, and benziodoxoles, e.g., II, were efficiently synthesized and derivatized in good to excellent yields with high selectivity. As only electrons serve as the oxidation reagents, this method offers a more straightforward and sustainable manner that avoids the use of expensive or hazardous chem. oxidants. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5Reference of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Reference of 2-Iodobenzoic acid Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com