Category: 7681-82-5

Synthetic Route of 7681-82-5, These common heterocyclic compound, 7681-82-5, name is Sodium iodide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Synthesis of 49; A Schlenk tube was charged with complex 3 (83.4 mg, 0.18 mmol), Nal (539.6 mg,3.6 mmol), and 5 mL of THF. The reaction mixture was stirred at room temperature for 8 h. All volatiles were removed under vacuum. The residue was dissolved in toluene, and the resulting suspension was passed through a plug of Celite. All the volatiles were removed, and the residue was washed with diethyl ether (3 x 5 mL) to give 49 as a dark red powder. Yield: 68% (78.5 mg, 0.12 mmol).1H NMR (CD2C12, 300 MHz): delta 7.19 (s, 2H,CHiinid), 5.69 (d, J = 5.91 Hz, 2H, CHpCym), 5.52 (septet, J = 6.60 Hz, 2H, CHiSoP imid), 5.15 (d, J = 5.88 Hz, 2H, CHpcym), 3.29 (septet, J = 6.93 Hz, 1H, CHjsop pcym ), 2.01 (s, 3H, CH3pcym), 1.44 (br, 12H, CH3isop imid), 1.32 (d,13C {1H} NMR (CD2C12, 100MHz): delta 167.6 (C-Ru), 120.1 (CHimid), 108.4 (Cqpcym), 99.8( qpcym), 87.3 (CHpcym), 82.3 (CHpcym), 55.0 (CHjsop jmid), 32.0 (CHjSop pcym), 25.7 (CH3jsop imid), 25.1 (CH3jsop imid), 23.2 (CH3isop pcym), 19.8 (CH3pcym).Anal, calcd for C20H32C12I2N2-Ru (49-3CH2Cl2, 726.3): C, 33.08; H, 4.44; N, 3.86. Found: C, 33.46; H, 4.01; N, 4.03.

The synthetic route of 7681-82-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; NANYANG TECHNOLOGICAL UNIVERSITY; HONG, Soon Hyeok; GHOSH, Subhash Chandra; ZHANG, Yao; MUTHAIAH, Senthilkumar; CHEN, Cheng; XU, Xiangya; WO2011/34506; (2011); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 7681-82-5 as follows. Recommanded Product: Sodium iodide

General procedure: Complexes 2 and 3 were synthesised by following a similar procedure as described for complex 1 but using anhydrous Cd(ClO4)2 (0.311g, 1mmol) and NaBr (0.101g, 1mmol) (For complex 2)/NaI (0.149g, 1mmol) (For complex 3) respectively instead of CdCl2 (0.183g, 1mmol). The needle shaped brown colored crystals of 2 and 3 were washed with a methanol-water mixture and dried in desiccator containing anhydrous CaCl2 and then characterized by elemental analysis, spectroscopic methods, and X-ray diffraction. Complex 2: Yield: 0.851g, 73.36% (with respect to CuL). Anal. Calc. for C50H40CdCu2Br2N4O4: C, 51.76; H, 3.48; N, 4.83. Found: C, 51.59; H, 3.41; N, 4.94%. IR (KBr pellet, cm-1): nu(C=N) 1603. UV/Vis: lambdamax(nm) [epsilonmax(M-1 cm-1)] in (DMF)=588(470), 383(29570), 313(62182). Complex 3: Yield: 0.910g, 72.56% (with respect to CuL). Anal. Calc. for C50H40CdCu2I2N4O4: C, 47.88; H, 3.21; N, 4.47. Found: C, 47.73; H, 3.07; N, 4.30%. IR (KBr pellet, cm-1): nu(C=N) 1602. UV/Vis: lambdamax(nm) [epsilonmax(M-1 cm-1)] in (DMF)=589(479), 382(38868), 313(81774).

According to the analysis of related databases, 7681-82-5, the application of this compound in the production field has become more and more popular.

Reference:
Article; Ganguly, Sayantan; Bauza, Antonio; Frontera, Antonio; Ghosh, Ashutosh; Inorganica Chimica Acta; vol. 492; (2019); p. 142 – 149;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 7681-82-5,Some common heterocyclic compound, 7681-82-5, name is Sodium iodide, molecular formula is INa, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To a round-bottomed flask were added dichloride(pentamethylcyclopentadienyl)iridium(III) dimer (0.1 mmol, 79.5 mg) and sodium iodide (1 mmol, 150 mg). The round-bottomed flask was equipped with a reflux condenser and capped with a rubber septum. An ultrapure argon flow was passed through the system for 30 min. Then, anhydrous acetone (10 mL) was added using syringe and needle, the ultrapure argon flow was reduced, and the reaction mixture was refluxed under stirring for 3 h. Afterwards, the solvent was evaporated under reduced pressure to give a solid which was dissolved in CH2Cl2 (20 mL), washed with distilled water (3 x 10 mL), and dried over Na2SO4. After filtration, the solvent was evaporated under reduced pressure, affording the desired catalyst. Yield: 107 mg (92%); reddish solid; Rf = 0.41 (eluent: dichloromethane); 1H NMR (300 MHz, CDCl3): delta 1.76 (s, 30H); 13C NMR (75 MHz, CDCl3): delta 88.8, 10.7; IR (KBr, cm-1) 3442.9, 2918.3, 1629.9; HRMS (ESI): m/z [M – I]+ calcd for C20H30I3Ir2: 1036.8740; found: 1036.8713

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Sodium iodide, its application will become more common.

Reference:
Article; Correa, Bianca K.; Silva, Tamiris R.C.; Raminelli, Cristiano; Tetrahedron Letters; vol. 59; 39; (2018); p. 3583 – 3585;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Adding a certain compound to certain chemical reactions, such as: 7681-82-5, name is Sodium iodide, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7681-82-5, Formula: INa

under a nitrogen atmosphere, and imidazolium salt 2d (20 mg, 0.03 mmol) was added to a 25mL Schlenk tube and dissolved in methylene chloride (2mL). Here silver oxide (7.0 mg, 0.30 mmol) was added, the dark, was stirred at room temperature for 16 hours. The nonbody precipitated afterthe reaction was removed by celite, by distilling a solution to quantitatively obtain silver (Ag) complex compound 7d of interest. Here, methylenechloride (2 mL) was added, PdCl 2 (MeCN) 2 (3.9 mg, 0.015 mmol) and the mixture was stirred at room temperature for 20 hours. After the reactionwas obtained 8d by distilling off the solvent (17.5mg). This was dissolved in methylene chloride (2 mL), sodium iodide (45 mg, 0.3 mmol) and themixture was stirred at room temperature for 20 hours. By distilling off the solvent after the reaction, to obtain a palladium (Pd) complex compound 9dof interest (yield: 19.8mg, 0.012mmol, yield: 80%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Sodium iodide, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; National Institute of Advanced Industrial Science and Technology; Taira, Toshiaki; Imura, Tomohiro; Komura, Nagatoshi; Kitamoto, Dai; (34 pag.)JP2016/98194; (2016); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Adding a certain compound to certain chemical reactions, such as: 7681-82-5, name is Sodium iodide, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7681-82-5, Recommanded Product: 7681-82-5

NaI (73 mg, 0.487 mmol) in CH2Cl2 (5 ml) was added to[Ni(Cl2(Lbenz)] 3a (90 mg, 121 mmol) in CH2Cl2 (10 ml). The mixturewas stirred 24 h, was filtered over Celite and was concentrated by volume to afford 100mg (90%) of 3c as a red solid that was isolatedby filtration. 1H NMR (CDCl3): d 7.62 (d, J 7.2, ortho, 4H, -C6H5),7.40 (t, J 7.6, meta, 4H, -C6H5), 7.31 (t, J 7.6, para, 2H, -C6H5),7.19e7.22 (m, 4H, benzimi -CH]CH), 7.13e7.15 (m, 4H, benzimi),5.29 (bs, 8H, -benzimi-NCH2), 3.75 (s, 4H, -NCH2Ph), 3.11 (bs, 8H,PhCH2CH2CH2), 2.59 (t, J 5.6, 8H, CH2NCH2Ph). 13C NMR (CD2Cl2):d 190.4, 141, 136, 129.5, 128.8, 127, 122, 109.6, 60, 54, 46, 30, 28. 13CNMR (CDCl3): d 190, 140, 136, 129, 128.7, 127, 122, 109, 59.5, 53, 46,27. HR FT-ICR MS: found 462.0680 (calcd for C40H46I2N6NiH, m/z[3c H]2 462.0686).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Reference:
Article; Thapa, Rajesh; Kilyanek, Stefan M.; Journal of Organometallic Chemistry; vol. 901; (2019);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Some common heterocyclic compound, 7681-82-5, name is Sodium iodide, molecular formula is INa, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Quality Control of Sodium iodide

General procedure: All reagents were ACS-reagent grade. Distilled water was used for the preparation of solutions. The procedure for the preparation of CaApOH is as follows: samples of 1.2g Ca(NO3)2·4H2O, 0.5g Na3PO4, and 0.04g NaOH were placed in the bottom of a 125mL Erlenmeyer flask equipped with a standard taper joint bearing a condenser with a thermometer inserted in the condenser and held slightly above the bottom of the flask (but in the solution) by a thin slice of suction tubing at the top of the condenser. The flask was placed on a heating/stir plate and 50mL of distilled water was added. The solution was stirred magnetically and heated to 80C for approximately 3h. The pH was measured, but not adjusted, at the beginning and at the end of the 3h of digestion using Hydrion pH 1.0-12.0 paper. [In order to determine the effect of pH, the pH was adjusted with 3 M NaOH for some samples at the beginning and during digestion.] Stirring was then discontinued and the solution was allowed to cool and settle overnight. The precipitate was suction filtered in a medium porosity glass filter crucible and washed 5 times with a total of about 150mL of distilled water. The precipitate was dried in a vacuum drying oven at 110 C for at least 4h and then ground with a mortar and pestle and stored in a closed, parafilmed vial.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 7681-82-5, its application will become more common.

Reference:
Article; Yoder, Claude H.; Havlusch, Maxwell D.; Dudrick, Robyn N.; Schermerhorn, Janse T.; Tran, Linh K.; Deymier, Alix C.; Polyhedron; vol. 127; (2017); p. 403 – 409;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 7681-82-5, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 7681-82-5 as follows.

General procedure: Nal (2.15 eq.) is added at room temperature to a suspension of PtCI2(1-R-1 ,5-COD)] (1.00 eq.; synthesized as described in Example 1 ) in acetone. The color of the reaction mixture initially turns yellow and the mixture is stirred for three hours. Afterwards the acetone is removed under reduced pressure and the resulting residue is dissolved in a mixture of dichloromethane and water (1 :1 ). The phases are separated and the organic phase is washed twice with water, dried over sodium sulfate and filtered. After removal of the solvent under reduced pressure, the desired Ptl2(1-R-1 ,5-COD) complex can be obtained as a bright yellow to orange solid or wax.50.0 mg (1 .00 eq., 0.128 mmol) [PtCI2(Me-COD)] and 43.2 mg (2.15 eq., 0.258 mmol) Nal in 3 mL acetone were stirred together for three hours. 71.1 mg (0.126 mmol, 97%) of the desired product could be obtained as yellow solid. – Decomposition temperature: >170 C. – 1H-NMR (400 MHz, CDCI3): delta (ppm) = 1.70- 1.90 (m, 1 H, CH2), 1.90-2.20 (m, 3 H, CH2), 2.08 (s d,2JPtH= 20.7 Hz, 3 H, CH3), 2.20- 2.40 (m, 2 H, CH2), 2.50-2.61 (m, 1 H, CH2), 2.61-2.80 (m, 1 H, CH2), 5.56-6.02 (m, 3 H, CH). -13C-NMR (100 MHz, CDCI3): delta (ppm) = 29.8 (-, CH2), 31 .9 (-, CH2), 32.3 (+, CH3), 32.5 (-, CH2), 36.2 (-, CH2), 99.5 (+, CH), 99.7 (+, CH), 101.1 (+, CH), 128.9 (Cquart). – 195Pt-NMR (129 MHz, CDCl3): delta (ppm) = -4240 (s). – IR (ATR) [cm-1]: v-1= 3000 (vw), 2940 (vw), 2874 (vw), 2825 (vw), 2108 (vw), 1718 (vw), 151 1 (vw), 1492 (vw), 1477 (vw), 1423 (w), 1368 (vw), 1347 (vw), 1335 (vw), 1312 (w), 1237 (vw), 1210 (vw), 1 191 (vw), 1 169 (vw), 1 142 (vw), 1095 (w), 1061 (vw), 1036 (vw), 1022 (vw), 1006 (w), 967 (vw), 939 (vw), 895 (vw), 874 (w), 853 (vw). – MS (70 eV, El), m/z (%): 574/572/571/570 (10/45/60/50) [M+], 445/444/443/442/441 (25/30/36/1 1/15) [M+- l], 316/315/314/313/312/31 1/310 (1 1 Pi 8/12/18/12/17/12) (13/23/76/84/86/55/60/36/38/28/13) [M+-2 I], 122 (52) [C9H14+], 107 (39) [CeHu*], 94 (41 ), 68 (100). – HRMS (Ptl2C9H14): calc. 570.8833; found 570.8831. – EA (Ptl2C9H14): calc. C 18.93, H 2.47; found C 19.70, H 2.58.

According to the analysis of related databases, 7681-82-5, the application of this compound in the production field has become more and more popular.

Application of 7681-82-5, These common heterocyclic compound, 7681-82-5, name is Sodium iodide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: A typical example is exemplified by the synthesis of 4b: To a stirred solution of TMEDA (1.36 mL,9 mmol) in hexane (5 mL) was added dropwise at ice bath temperature n-butyllithium (9 mmol) in hexane followed by acetophenone trimethylsilyl enol ether 1 (576 mg, 3 mmol), and the mixture was stirred for 24 h at room temperature. In a separate flask, a mixture of bismuth(III) chloride (315.5 mg,1 mmol) and tris(4-methylphenyl)bismuthane (964 mg, 2 mmol) was stirred in ether (10 mL) at room temperature for 1 h. To the suspension of chlorobis(4-methylphenyl)bismuthane (ca. 3 mmol) thus formed was added sodium iodide (450 mg, 3 mmol) and a few drops of 15-crown-5 ether and the resulting yellowish mixture was stirred for 3 h at room temperature. To a suspension of the lithium compound previously prepared was added at room temperature magnesium dibromide diethyl etherate (775 mg, 3 mmol) followed by, at -30 C, a suspension of iodobis(4-methylphenyl)bismuthane(ca. 9 mmol), and the resulting mixture was stirred for 1 h, during which time the temperature was raised to ambient temperature. The reaction mixture was poured into brine (50 mL) and extracted with ethyl acetate (50 mL ¡Á 3). The combined extracts were concentrated to leave an oily residue, which was purified by chromatography (silica gel) using hexane-ethyl acetate (5:1) as the eluent to afford 4b in 30% yield (459 mg, 0.9 mmol). Because 4a, 4f and 10 underwent decomposition when purified by chromatography on silica gel, these compounds were converted into the corresponding halobismuthanes 5a, 5f and 11, respectively, without isolation.

Statistics shows that Sodium iodide is playing an increasingly important role. we look forward to future research findings about 7681-82-5.

Reference:
Article; Murafuji, Toshihiro; Tomura, Mai; Ishiguro, Katsuya; Miyakawa, Isamu; Molecules; vol. 19; 8; (2014); p. 11077 – 11095;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

7681-82-5, name is Sodium iodide, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 7681-82-5

General procedure: A typical example is exemplified by the synthesis of 4b: To a stirred solution of TMEDA (1.36 mL,9 mmol) in hexane (5 mL) was added dropwise at ice bath temperature n-butyllithium (9 mmol) in hexane followed by acetophenone trimethylsilyl enol ether 1 (576 mg, 3 mmol), and the mixture was stirred for 24 h at room temperature. In a separate flask, a mixture of bismuth(III) chloride (315.5 mg,1 mmol) and tris(4-methylphenyl)bismuthane (964 mg, 2 mmol) was stirred in ether (10 mL) at room temperature for 1 h. To the suspension of chlorobis(4-methylphenyl)bismuthane (ca. 3 mmol) thus formed was added sodium iodide (450 mg, 3 mmol) and a few drops of 15-crown-5 ether and the resulting yellowish mixture was stirred for 3 h at room temperature. To a suspension of the lithium compound previously prepared was added at room temperature magnesium dibromide diethyl etherate (775 mg, 3 mmol) followed by, at -30 C, a suspension of iodobis(4-methylphenyl)bismuthane(ca. 9 mmol), and the resulting mixture was stirred for 1 h, during which time the temperature was raised to ambient temperature. The reaction mixture was poured into brine (50 mL) and extracted with ethyl acetate (50 mL ¡Á 3). The combined extracts were concentrated to leave an oily residue, which was purified by chromatography (silica gel) using hexane-ethyl acetate (5:1) as the eluent to afford 4b in 30% yield (459 mg, 0.9 mmol). Because 4a, 4f and 10 underwent decomposition when purified by chromatography on silica gel, these compounds were converted into the corresponding halobismuthanes 5a, 5f and 11, respectively, without isolation.

The synthetic route of 7681-82-5 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Murafuji, Toshihiro; Tomura, Mai; Ishiguro, Katsuya; Miyakawa, Isamu; Molecules; vol. 19; 8; (2014); p. 11077 – 11095;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 7681-82-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 7681-82-5, name is Sodium iodide belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

A mixture of propionic acid (10 ml), sodium iodide (3.0 g, 20 mmol) and Fe3+- montmorillonite catalyst (0.5 g) were stirred in a round-bottomed flask at 25 C for 6 h. The reaction mixture was filtered off to separate the catalyst. The resultant filtrate was titrated with 0. 1M sodium thiosulphate solution using starch as an indicator to know the amount of iodine present in the solution. The amount of iodine liberated in the reaction is 0.998 g (3.7 mmol)

The synthetic route of Sodium iodide has been constantly updated, and we look forward to future research findings.

Reference:
Patent; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH; WO2004/50622; (2004); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com