Category: 676267-05-3

Rapid Access to Dibenzohelicenes and their Functionalized Derivatives was written by Jancarik, Andrej;Rybacek, Jiri;Cocq, Kevin;Vacek Chocholousova, Jana;Vacek, Jaroslav;Pohl, Radek;Bednarova, Lucie;Fiedler, Pavel;Cisarova, Ivana;Stara, Irena G.;Stary, Ivo. And the article was included in Angewandte Chemie, International Edition in 2013.Category: iodides-buliding-blocks The following contents are mentioned in the article:

Easy access to dibenzo[5]-, dibenzo[6]- and dibenzo[7]helicenes (I – III) and their derivatives includes Sonogashira and Suzuki-Miyaura couplings, desilylation, and [2+2+2] alkyne cycloisomerization. The simplicity of this non-photochem. approach combined with the potential for helicity control favors dibenzohelicenes over the parent helicenes for practical applications. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Category: iodides-buliding-blocks).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A novel synthetic approach towards chiral QUINAP via diastereomeric sulfoxide intermediates was written by Thaler, Tobias;Geittner, Florian;Knochel, Paul. And the article was included in Synlett in 2007.Application In Synthesis of 2-Bromo-1-iodonaphthalene The following contents are mentioned in the article:

A novel enantioselective synthesis of chiral QUINAP is described. Hereby, the separation of the diastereomers was achieved by the preparation and simple chromatog. separation of chiral sulfoxide intermediates. Subsequent sulfoxide-lithium exchange, quenching with Ph₂PCl and sulfur, and then desulfurization with Raney-Ni provided (R)- and (S)-QUINAP in 54-56% overall yield. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Application In Synthesis of 2-Bromo-1-iodonaphthalene).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Application In Synthesis of 2-Bromo-1-iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ir-Catalyzed Synthesis of Substituted Tribenzosilepins by Dehydrogenative C-H/Si-H Coupling was written by Shibata, Takanori;Uno, Ninna;Sasaki, Tomoya;Takano, Hideaki;Sato, Tatsuki;Kanyiva, Kyalo Stephen. And the article was included in Journal of Organic Chemistry in 2018.Computed Properties of C10H6BrI The following contents are mentioned in the article:

The Ir-catalyzed intramol. reaction of 2′,6′-diaryl-2-(hydrosilyl)biphenyls gave substituted tribenzosilepins by direct dehydrogenative C-H/Si-H coupling. This is the 1st example of catalytic construction of the tribenzosilepin skeleton. Enantiomerically pure tribenzosilepin was prepared by optical resolution using chiral HPLC, and its inversion barrier was calculated by measurement of rate of racemization using the Eyring kinetic equation under heating conditions. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Computed Properties of C10H6BrI).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Computed Properties of C10H6BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

[2+2+2] Cycloisomerisation of Aromatic Cyanodiynes in the Synthesis of Pyridohelicenes and Their Analogues was written by Klivar, Jiri;Jancarik, Andrej;Saman, David;Pohl, Radek;Fiedler, Pavel;Bednarova, Lucie;Stary, Ivo;Stara, Irena G.. And the article was included in Chemistry – A European Journal in 2016.Electric Literature of C10H6BrI The following contents are mentioned in the article:

We have developed a methodol. for the synthesis of pyridohelicenes and their analogs based on the Ni⁰-, Co^I– or Rh^I-mediated intramol. [2+2+2] cycloisomerization of cyanodiynes. It allows for folding the linear precursors into the corresponding helical backbones comprising the newly formed pyridine unit in their central part. Along with racemic pyrido[n]helicenes (n=5,6,7) and their derivatives, both enantio- and diastereomerically pure pyrido[n]helicene-like mols. (n=5,6) were prepared by employing the chiral substrate-controlled cyclization of the corresponding enantiopure cyanodiynes. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Electric Literature of C10H6BrI).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Electric Literature of C10H6BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Copper-Catalyzed N,N-Diarylation of Amides for the Construction of 9,10-Dihydroacridine Structure and Applications in the Synthesis of Diverse Nitrogen-Embedded Polyacenes was written by Tan, Mei-Ling;Tong, Shuo;Hou, Sheng-Kai;You, Jingsong;Wang, Mei-Xiang. And the article was included in Organic Letters in 2020.Category: iodides-buliding-blocks The following contents are mentioned in the article:

A CuI/DMEDA catalyzed N,N-diarylation reaction of amides with various di(o-bromoaryl)methanes to produce diverse 9,10-dihydroacridine derivatives, is reported. The resulting 9,10-dihydroacridine derivatives were oxidized selectively under mild conditions to afford acridine, acridinone, and acridinium derivatives The copper-catalyzed N,N-diarylation reaction coupled with oxidative aromatization reaction enabled the facile construction of nitrogen atom-embedded tetracenes and pentacenes of different ortho-fused patterns. The luminescence properties, especially the effect of fusion pattern on fluorescence emission of acquired N-polyacenes, were also demonstrated. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Category: iodides-buliding-blocks).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Novel Synthesis of Benzalacetone Analogues of Naphth[a]azulenes by Intramolecular Tropylium Ion-Mediated Furan Ring-Opening Reaction and X-ray Investigation of a Naphth[1,2-a]azulene Derivative was written by Yamamura, Kimiaki;Kawabata, Shizuka;Kimura, Takatomo;Eda, Kazuo;Hashimoto, Masao. And the article was included in Journal of Organic Chemistry in 2005.Computed Properties of C10H6BrI The following contents are mentioned in the article:

Benzalacetone analogs of naphth[1,2-a]azulene (I), naphth[2,1-a]azulene, and naphth[2,3-a]azulene were synthesized from 2-(5-methyl-2-furyl)-1-, 1-(5-methyl-2-furyl)-2-, and 2-(5-methyl-2-furyl)-3-tropylionaphthalene, resp. The synthetic method is based on furan ring-opening reaction by the intramol. electrophilic attack of a tropylium ion. Single-crystal X-ray work on I revealed that its tetracyclic system exhibited deformation from planarity similar to that of benzo[c]phenanthrene (tetrahelicene). A centrosym. associated dimer structure, just like the mols. of carboxylic acids but via C:O···H-C hydrogen bonds, was found in the crystal. Reduction of bond-length alternation in the seven-membered ring was also found. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Computed Properties of C10H6BrI).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Computed Properties of C10H6BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bronsted acid-enhanced copper-catalyzed atroposelective cycloisomerization to axially chiral arylquinolizones via dearomatization of pyridine was written by Min, Xiao-Long;Zhang, Xiu-Lian;Yi, Wenbin;He, Ying. And the article was included in Nature Communications in 2022.Quality Control of 2-Bromo-1-iodonaphthalene The following contents are mentioned in the article:

Herein, the enantioselective synthesis of axially chiral arylquinolizones through an intramol. atroposelective cycloisomerization was reported. The reaction proceeds via the Bronsted acid-enhanced dearomatization of pyridine by a copper catalyst that allows for the formation of the desired products in excellent yields and enantioselectivities. The utility of this methodol. was illustrated by a synthesis on gram scale production and transformation of the products into chiral thiourea catalysts. Mechanistic studies demonstrate that Bronsted acid plays a significant role in promoting the reactivity of the reaction, while both the steric and electronic effects of aryl substituents in substrate play a role in controlling the stereoselectivity. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Quality Control of 2-Bromo-1-iodonaphthalene).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Quality Control of 2-Bromo-1-iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rhodium-Catalyzed Enantioselective Synthesis, Structures, and Properties of Single and Double Azahelicene-Like Molecules was written by Hanada, Kyoichi;Nogami, Juntaro;Miyamoto, Kazunori;Hayase, Norihiko;Nagashima, Yuki;Tanaka, Yusuke;Muranaka, Atsuya;Uchiyama, Masanobu;Tanaka, Ken. And the article was included in Chemistry – A European Journal in 2021.SDS of cas: 676267-05-3 The following contents are mentioned in the article:

The enantioselective synthesis of aza[6] and [7]helicene-like mols. have been achieved by the cationic rhodium(I)/axially chiral biaryl bisphosphine complex-catalyzed intramol. [2+2+2] cycloaddition of cyanodiynes [e.g., I → (P)-II (optimized at 87%, 62% ee using (R)-xyl-segphos)]. This protocol was successfully applied to the diastereo- and enantioselective synthesis of an S-shaped double aza[6]helicene-like mol. with a high ee value of 89%. Although no epimerization and racemization were observed in the double carbo[6]helicene-like mol. at 80°C, epimerization and racemization of the double aza[6]helicene-like mol. proceeded at 80°C. This double aza[6]helicene-like mol. showed good fluorescent quantum yields and chiroptical responses under both neutral and acidic conditions. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3SDS of cas: 676267-05-3).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.SDS of cas: 676267-05-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Catalytic Atropenantioselective Heteroannulation between Isocyanoacetates and Alkynyl Ketones: Synthesis of Enantioenriched Axially Chiral 3-Arylpyrroles was written by Zheng, Sheng-Cai;Wang, Qian;Zhu, Jieping. And the article was included in Angewandte Chemie, International Edition in 2019.Application of 676267-05-3 The following contents are mentioned in the article:

In the presence of Ag₂O and a quinine- or quinidine-derived phosphine, arylethynyl aryl ketones such as I (R = Ph, 4-BrC₆H₄, 4-ClC₆H₄, 4-MeOC₆H₄, 4-MeC₆H₄, 4-t-BuC₆H₄, 3-MeOC₆H₄; R¹ = Me, Et, i-Pr, Ac) underwent enantioselective cycloaddition reactions with isocyanoacetates such as Et isocyanoacetate to yield (aryl)aroylpyrrolecarboxylates such as II (R = Ph, 4-BrC₆H₄, 4-ClC₆H₄, 4-MeOC₆H₄, 4-MeC₆H₄, 4-t-BuC₆H₄, 3-MeOC₆H₄; R¹ = Me, Et, i-Pr, Ac) in 46-98% yields and in 82-96% ee. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Application of 676267-05-3).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Application of 676267-05-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Asymmetric Synthesis of Nonracemic 2-Amino[6]helicenes and Their Self-Assembly into Langmuir Films was written by Karras, Manfred;Holec, Jan;Bednarova, Lucie;Pohl, Radek;Schmidt, Bernd;Stara, Irena G.;Stary, Ivo. And the article was included in Journal of Organic Chemistry in 2018.Application of 676267-05-3 The following contents are mentioned in the article:

Alternative ways of preparing nonracemic 2-amino[6]helicene derivatives were explored. The enantioselective [2 + 2 + 2] cycloisomerization of a nonchiral triyne under Ni(cod)₂/(R)-QUINAP catalysis delivered the enantioenriched (+)-(P)-2-aminodibenzo[6]helicene derivative in 67% ee. An ultimate “point-to-helical” chirality transfer was observed in the cyclization of enantiopure triynes mediated by Ni(CO)₂(PPh₃)₂ affording (-)-(M)- or (+)-(P)-7,8-bis(p-tolyl)hexahelicen-2-amine in >99% ee as well as its benzoderivative in >99% ee. The latter mode of stereocontrol was inefficient for a 2-aminobenzo[6]helicene congener with an embedded five-membered ring. The rac-, (-)-(M)-, and (+)-(P)-7,8-bis(p-tolyl)hexahelicen-2-amines formed Langmuir monolayers at the air-water interface featuring practically identical surface pressure vs mean mol. area isotherms. The corresponding Langmuir-Blodgett films on quartz or silicon substrates were characterized by UV-vis/ECD spectroscopy and AFM microscopy, resp. This study involved multiple reactions and reactants, such as 2-Bromo-1-iodonaphthalene (cas: 676267-05-3Application of 676267-05-3).

2-Bromo-1-iodonaphthalene (cas: 676267-05-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Application of 676267-05-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com