Category: 626-02-8

Computed Properties of C6H5IOIn 2020 ,《Chi-MIC-share: a new feature selection algorithm for quantitative structure-activity relationship models》 was published in RSC Advances. The article was written by Li, Yuting; Dai, Zhijun; Cao, Dan; Luo, Feng; Chen, Yuan; Yuan, Zheming. The article contains the following contents:

Quant. structure-activity relationship models are used in toxicol. to predict the effects of organic compounds on aquatic organisms. Common filter feature selection methods use correlation statistics to rank features, but this approach considers only the correlation between a single feature and the response variable and does not take into account feature redundancy. Although the minimal redundancy maximal relevance approach considers the redundancy among features, direct removal of the redundant features may result in loss of prediction accuracy, and cross-validation of training sets to select an optimal subset of features is time-consuming. In this paper, we describe the development of a feature selection method, Chi-MIC-share, which can terminate feature selection automatically and is based on an improved maximal information coefficient and a redundant allocation strategy. We validated Chi-MIC-share using three environmental toxicol. datasets and a support vector regression model. The results show that Chi-MIC-share is more accurate than other feature selection methods. We also performed a significance test on the model and analyzed the single-factor effects of the reserved descriptors. In the experiment, the researchers used many compounds, for example, 3-Iodophenol(cas: 626-02-8Computed Properties of C6H5IO)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Computed Properties of C6H5IOHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases》 was written by Dao, Viet Hung; Ourliac-Garnier, Isabelle; Loge, Cedric; McCarthy, Florence O.; Bach, Stephane; da Silva, Teresinha Goncalves; Denevault-Sabourin, Caroline; Thiefaine, Jerome; Baratte, Blandine; Robert, Thomas; Gouilleux, Fabrice; Brachet-Botineau, Marie; Bazin, Marc-Antoine; Marchand, Pascal. HPLC of Formula: 626-02-8 And the article was included in Molecules in 2021. The article conveys some information:

Pim kinases (proviral integration site for Moloney murine leukemia virus kinases) are overexpressed in various types of hematol. malignancies and solid carcinomas, and promote cell proliferation and survival. Thus, Pim kinases are validated as targets for antitumor therapy. In this context, our combined efforts in natural product-inspired library generation and screening furnished very promising dibenzo[b,d]furan derivatives derived from cercosporamide. Among them, lead compound 44 was highlighted as a potent Pim-1/2 kinases inhibitor with an addnl. nanomolar IC50 value against CLK1 (cdc2-like kinases 1) and displayed a low micromolar anticancer potency towards the MV4-11 (AML) cell line, expressing high endogenous levels of Pim-1/2 kinases. The design, synthesis, structure-activity relationship, and docking studies are reported herein and supported by enzyme, cellular assays, and Galleria mellonella larvae testing for acute toxicity. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8HPLC of Formula: 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.HPLC of Formula: 626-02-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

You, Shengyong; Zhang, Rongli; Cai, Mingzhong published their research in Synthesis in 2021. The article was titled 《A Magnetically Recyclable Palladium-Catalyzed Formylation of Aryl Iodides with Formic Acid as CO Source: A Practical Access to Aromatic Aldehydes》.Application In Synthesis of 3-Iodophenol The article contains the following contents:

A magnetically recyclable palladium-catalyzed formylation of aryl iodides ArI (Ar = C6H5, 3-pyridyl, 2-furyl, etc.) under CO gas-free conditions has been developed by using a bidentate phosphine ligand-modified magnetic nanoparticles-anchored palladium(II) complex [2P-Fe3O4@SiO2-Pd(OAc)2] as catalyst, yielding a wide variety of aromatic aldehydes ArCHO in moderate to excellent yields. Here, formic acid was employed as both the CO source and the hydrogen donor with iodine and PPh3 as the activators. This immobilized palladium catalyst can be obtained via a simple preparative procedure and facilely recovered simply by using an external magnetic field, and reused at least 9 times without any apparent loss of catalytic activity. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8Application In Synthesis of 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Application In Synthesis of 3-Iodophenol Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Li, Zhijun; Zhang, Mingyang; Zhang, Lili; Dong, Xiuli; Leng, Leipeng; Horton, J. Hugh; Wang, Jun published an article in Nano Research. The title of the article was 《Engineering the atomic interface of porous ceria nanorod with single palladium atoms for hydrodehalogenation reaction》.Name: 3-Iodophenol The author mentioned the following in the article:

Tuning the electronic properties of single atom catalysts (SACs) between the central metal and the neighboring surface atoms has emerged as an efficient strategy to boost catalytic efficiency and metal utilization. Here we describe a simple and efficient approach to create atomically dispersed palladium atoms supported over defect-contg porous ceria nanorod contg palladium up to 0.26 weight The existence of singly dispersed palladium atoms is confirmed by spherical aberration correction electron microscopy and extended X-ray absorption fine structure measurements. This catalyst shows excellent efficiency in hydrodehalogenation reactions at low H2 pressure under mild conditions, along with satisfactory recyclability and scalability. D. functional theory (DFT) calculations reveal that the high activity stems from the spatial isolation of palladium atoms and the modified electronic structure of palladium confined in defect-containing ceria nanorod. This work may lay the foundation for the facile creation of single atom catalysts within the synthetic community and shed light on the possibility for scale-up prodn graphic not available see fulltext. The results came from multiple reactions, including the reaction of 3-Iodophenol(cas: 626-02-8Name: 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Name: 3-IodophenolHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of C6H5IOIn 2021 ,《SuFExable polymers with helical structures derived from thionyl tetrafluoride》 was published in Nature Chemistry. The article was written by Li, Suhua; Li, Gencheng; Gao, Bing; Pujari, Sidharam P.; Chen, Xiaoyan; Kim, Hyunseok; Zhou, Feng; Klivansky, Liana M.; Liu, Yi; Driss, Hafedh; Liang, Dong-Dong; Lu, Jianmei; Wu, Peng; Han, Zuilhof; Moses, John; Sharpless, K. Barry. The article contains the following contents:

Sulfur(VI) fluoride exchange (SuFEx) is a category of click chem. that enables covalent linking of modular units through sulfur(VI) connective hubs. The efficiency of SuFEx and the stability of the resulting bonds have led to polymer chem. applications. Now, we report the SuFEx click chem. synthesis of several structurally diverse SOF4-derived copolymers based on the polymerization of bis(iminosulfur oxydifluorides) and bis(aryl silyl ethers). This polymer class presents two key characteristics. First, the [-N=S(=O)F-O-] polymer backbone linkages are themselves SuFExable and undergo precise SuFEx-based post-modification with phenols or amines to yield branched functional polymers. Second, studies of individual polymer chains of several of these new materials indicate helical polymer structures. The robust nature of SuFEx click chem. offers the potential for post-polymerization modification, enabling the synthesis of materials with control over composition and conformation. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8Electric Literature of C6H5IO)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Electric Literature of C6H5IO In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthetic Route of C6H5IOIn 2021 ,《Access to S-Stereogenic Free Sulfoximines via Bifunctional Phosphonium Salt-Catalyzed Desymmetrization of Bisphenols》 was published in ACS Catalysis. The article was written by Fang, Siqiang; Liu, Zanjiao; Zhang, Hongkui; Pan, Jianke; Chen, Yuan; Ren, Xiaoyu; Wang, Tianli. The article contains the following contents:

Sulfur-stereogenic sulfoximines particularly with a free N-H unit exhibit intriguing chem. and biol. activities, and thus have received continuous attention from chemists. However, there are currently no examples of guiding catalytic asym. strategies available to directly access these mols. Herein, an efficient and practical protocol for the direct enantioenrichment of free N-H sulfoximines via a bifunctional phosphonium salt-catalyzed desymmetrization triggered by the Atherton-Todd reaction together with a further extended nucleophilic acyl substitution-type reaction has been disclosed. A series of free N-H sulfoximines bearing an assortment of aromatic groups (70 examples) was tolerated in this desymmetrization with incidentally involving minority kinetic resolution (KR). The desymmetrized products can be easily transformed into chiral sulfoxides and other classes of active sulfur-stereogenic compounds Mechanistic studies provided insights into the reaction pathway particularly suggesting a desymmetrization/KR synergic process, and also offered support on hydrogen-bonding interactions as the key elements to successful stereocontrol. In the experiment, the researchers used 3-Iodophenol(cas: 626-02-8Synthetic Route of C6H5IO)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Synthetic Route of C6H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Hongsheng; Zhao, Junhao; Yi, Songjian; Hu, Kongzhen; Feng, Pengju published their research in Organometallics in 2021. The article was titled 《Consequent Construction of C-C and C-N Bonds via Palladium-Catalyzed Dual C-H Activation: Synthesis of Benzo[c]cinnoline Derivatives》.COA of Formula: C6H5IO The article contains the following contents:

A highly efficient palladium-catalyzed cascade annulation of pyrazolones and aryl iodides to access various benzo[c]cinnoline derivatives has been achieved at 80°C. A pyridine-type ligand could improve the reaction efficiency under current reaction conditions, giving a higher product yield up to 94%. This novel approach provided a one-pot dual C-H activation strategy with good functional group tolerance, such as halogen, methoxy, nitro, ester, phenol, and so forth. The product could readily convert into cinnoline derivatives In addition to this study using 3-Iodophenol, there are many other studies that have used 3-Iodophenol(cas: 626-02-8COA of Formula: C6H5IO) was used in this study.

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.COA of Formula: C6H5IOHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Peng, Dao; Zhang, Yu; Liu, Xiao-Qing; Shang, Hang; Lin, Gang; Jin, Hong-Ying; Liu, Xue-Fen; He, Ran; Shang, Ye-Han; Xu, Yin-Hua; Luo, Shu-Ping published an article in Molecular Catalysis. The title of the article was 《Highly active and reusable copper phthalocyanine derivatives catalyzed the hydroxylation of (hetero)aryl halides》.Product Details of 626-02-8 The author mentioned the following in the article:

Authors have researched and developed a series of copper phthalocyanine derivatives as new highly active and reusable catalysts for the hydroxylation of (hetero)aryl halides. The perfluorinated copper phthalocyanine (CuPcF16) showed the highest activity for the hydroxylation of aryl iodide with an excellent yield (up to 98%) under low catalytic loading (0.5 mol% CuPcF16). Similarly, the hydroxylation of aryl bromides and aryl chlorides catalyzed by CuPcF16 also had high activity with 42-98% yield. Moreover, the recyclability of this catalyst can up to 6 times without significant loss in catalytic activity. In addition to this study using 3-Iodophenol, there are many other studies that have used 3-Iodophenol(cas: 626-02-8Product Details of 626-02-8) was used in this study.

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Product Details of 626-02-8 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Preparation, Characterization and First Application of Graphene Oxide-Metformin-Nickel for the Suzuki Cross-Coupling Reaction》 was published in ChemistrySelect in 2020. These research results belong to Raoufi, Farveh; Monajjemi, Majid; Aghaei, Hossein; Zare, Karim; Ghaedi, Mehrorang. Category: iodides-buliding-blocks The article mentions the following:

In this project, in the first step, the graphene oxide-metformin nickel catalyst I has been prepared and then the Ni(II) was reduced to Ni(0) by hydrazine hydrate and Ni(0) nanoparticle coordinated to metformin-GO was achieved. After full characterization of catalyst structure by different analyses like Fourier-transform IR spectroscopy (FT-IR), transmission electron microscopy (TEM), SEM (SEM), energy dispersive X-Ray anal. (EDX), X-Ray diffraction anal. (XRD), thermal gravimetric anal. (TGA), and coupled plasma/at. emission spectroscopy (ICP), as well as confirmation of the successful synthesis of catalyst, the activity of catalyst has been examined in the Suzuki-Miyaura cross-coupling reaction. In addition to this study using 3-Iodophenol, there are many other studies that have used 3-Iodophenol(cas: 626-02-8Category: iodides-buliding-blocks) was used in this study.

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Category: iodides-buliding-blocks In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Synthesis of 18F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination》 was written by Kwon, Young-Do; Jeon, Min Ho; Park, Nam Kyu; Seo, Jeong Kon; Son, Jeongmin; Ryu, Young Hoon; Hong, Sung You; Chun, Joong-Hyun. Related Products of 626-02-8 And the article was included in Organic Letters in 2020. The article conveys some information:

Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F transfer reactions have limited 18F-radiochem. translation, due to the inaccessibility of gaseous [18F]SO2F2. Herein, we report the first SO2F2-free synthesis of aryl [18F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced 18F-. The radiochem. yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [18F]fluorosulfate. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8Related Products of 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Related Products of 626-02-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com