In 2019,Organic Chemistry Frontiers included an article by Chen, Xiaoyan; Zhou, Hao; Chen, Zhiyuan. Safety of Methyl 2-Fluoro-5-iodobenzoate. The article was titled 《Pd/P/dba-Promoted cascade annulations to produce fused medium-sized sulfoximine polyheterocycles》. The information in the text is summarized as follows:
The Pd-catalyzed multicomponent reactions of NH-sulfoximines, Ph iodides and norbornadiene (NBD) were reported to chemoselectively produced fused medium-sized sulfoximine polyheterocycles in good to excellent yields. The addition of the dibenzylideneacetone (dba) ligand was found to be useful for this tandem annulation reaction. Under the optimized conditions, a broad range of 3D-type heterocyclic sulfoximines with good functional group tolerance were generated. In the experiment, the researchers used Methyl 2-Fluoro-5-iodobenzoate(cas: 625471-27-4Safety of Methyl 2-Fluoro-5-iodobenzoate)
Methyl 2-Fluoro-5-iodobenzoate(cas: 625471-27-4) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Safety of Methyl 2-Fluoro-5-iodobenzoate Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com