Category: 624-73-7

In 2016,McNeece, Andrew J.; Mokhtarzadeh, Charles C.; Moore, Curtis E.; Rheingold, Arnold L.; Figueroa, Joshua S. published 《Nickel bis-m-terphenylisocyanide dihalide complexes formed from 1,2-alkyl dihalides: probing for isolable β-haloalkyl complexes of square planar nickel》.Journal of Coordination Chemistry published the findings.Name: 1,2-Diiodoethane The information in the text is summarized as follows:

The pentachloroethyl complex NiCl(CCl2CCl3)(CNArMes2)2 (ArMes2 = 2,6-(2,4,6-Me3C6H2)2C6H3) was recently shown to be a unique example of an isolable β-chloroalkyl complex of square planar Ni. In an effort to generate addnl. β-haloalkyl complexes of square planar nickel, the reactivity of the precursor complex Ni(COD)(CNArMes2)2 with alkyl halides was probed. Treatment of Ni(COD)(CNArMes2)2 with 1,2-dichloroethane results in the exclusive formation of the dichloride complex NiCl2(CNArMes2)2 without the buildup of detectable intermediates. Similarly, Ni(COD)(CNArMes2)2 reacts with either 1,2-dibromoethane or 1,2-diiodoethane to produce the dibromide, NiBr2(CNArMes2)2, and diiodide, NiI2(CNArMes2)2, species, resp. Observable intermediates were also not detected in these latter reactions, indicating that either β-halo elimination is rapid or 1e- halogen-atom abstraction pathways are accessible to Ni(COD)(CNArMes2)2. The sterically and electronically modified m-terphenyl isocyanides CNArDipp2 and CNArClips2 (ArDipp2 = 2,6-(2,6-(i-Pr)2C6H3)2C6H3; ArClips2 = 2,6-(2,6-(Cl)2C6H3)2-4-(t-Bu)C6H2) were also studied as ancillary ligands for stabilization of a β-chloroalkyl complex of square planar nickel. Treatment of the zero-valent precursors Ni(COD)(CNArDipp2)2 and Ni(COD)(CNArClips2)2 with either 1,2-dichloroethane or hexachloroethane resulted in rapid formation of the dichlorides NiCl2(CNArDipp2)2 and NiCl2(CNArClips2)2 as exclusive products. These results highlight the unique combination of steric and electronic properties that lead to the stability of the parent β-chloroalkyl complex NiCl(CCl2CCl3)(CNArMes2)2. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7Name: 1,2-Diiodoethane) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Name: 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Synthesis, characterization and catalytic activity of ionic liquid mimic halides modified MCM-41 for solvent free synthesis of phenyl glycidyl carbonate》 were Ramalingam, R. Jothi; Appaturi, Jimmy Nelson; Pulingam, Thiruchelvi; Ibrahim S, Noora; Al-Lohedan, Hamad A.. And the article was published in Materials Chemistry and Physics in 2019. Application of 624-73-7 The author mentioned the following in the article:

The different type of halide modified mesoporous silica catalysts were prepared via post-grafting technique using meso-silica derived from rich husk by simple sol-gel method. The physico chem. characterizations of as prepared catalysts were characterized using FT-IR, N2-sorption-desorption study, 13C CP/MAS NMR and SEM techniques. FT-IR and 13C CP/MAS NMR revealed the effective anchorage of imidazole and 1,2-dihaloethane on the MCM-41. SEM anal. images shows the comprise worm-like agglomerated structure which was similar to MCM-41. The catalysts were then used in cycloaddition of carbon dioxide and Ph glycidyl ether under solvent free or less conditions. Among the prepared catalyst, Br-immobilized MCM-41 shows higher catalytic activity (96.7%) under ambient reaction by adopting following conditions such as 100°C, 20 bar initial CO2 pressure, 300 mg catalyst mass and 3 h. The conversion of Ph glycidyl ether using ImI-MCM-41 and ImCl-MCM-41 are 77.3% and 26.4% resp. The catalytic results are confirmed that the synergistic effect owing to the stronger nucleophilicity of bromide- and amine could be promoted the reaction smoothly. The catalyst was recovered and reused for four times without a significant decrease in activity or product selectivity. A possible site for CO2 activation by ImBr-MCM-41 catalyst could be the potential ionic liquid mimic’s halide immobilized MCM-41 like material for efficient conversion of the substrates such as Ph glycidyl ether and Epoxy hexane for cycloaddition reactions have been demonstrated.1,2-Diiodoethane(cas: 624-73-7Application of 624-73-7) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Application of 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 624-73-7In 2016 ,《Poly(paraphenylene sulfide) and Poly(metaphenylene sulfide) via Light-Initiated SRN1-Type Polymerization of Halogenated Thiophenols》 appeared in Macromolecular Rapid Communications. The author of the article were Heine, Niklas B.; Studer, Armido. The article conveys some information:

In this work, the synthesis of various halogenated thiophenol derivatives is presented. These thiophenols are used as monomers in light-initiated SRN1-type radical polymerization reactions. The method provides easy access to industrially relevant poly(paraphenylene sulfide) and poly(metaphenylene sulfide). The influence of the halide leaving group and of other substituents in the thiophenol monomer on the polymerization process is investigated. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7Application of 624-73-7) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Application of 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2016,Abbasi, M. A.; Tariq, S.; Aziz-ur-Rehman; Siddiqui, S. Z.; Ahmad, I.; Malik, R.; Shah, S. A. A. published 《Synthesis of some new N-substituted-N-(2,3-dihydro-[1,4]benzodioxin-6-yl)-4-acetamidobenzenesulfonamides as valuable antibacterial agents》.Russian Journal of Bioorganic Chemistry published the findings.Name: 1,2-Diiodoethane The information in the text is summarized as follows:

The aim of the present research was to investigate the antibacterial potential of some N-substituted sulfonamides bearing a benzodioxane moiety, I (R = Et, iso-Pr, CH2Ph, 2-ClC6H4CH2, etc.). The synthesis was started by reacting N-2,3-dihydrobenzo[1,4]dioxin-6-amine with 4-acetamidobenzene-1-sulfonyl chloride in the presence of 10% aqueous Na2CO3 solution to yield N-(2,3-dihydrobenzo[1,4]-dioxin-6-yl)-4-acetamidobenzenesulfonamide (II). II was further reacted with alkyl/aralkyl halides in DMF and lithium hydride as a base to obtain products I. All the synthesized compounds were characterized by spectral data (IR, 1H NMR, EI-MS, and HR-MS). The compounds were tested for antibacterial activity and most of them exhibited potent therapeutic potential against various Gram-neg. and Gram-pos. strains. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7Name: 1,2-Diiodoethane)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2015,Mahamulkar, Shraddha G.; Cisarova, Ivana; Jahn, Ullrich published 《The Lithiation Reactivity and Selectivity of Differentially Branched Alkyldiphenylphosphine Oxides – A Simple and Versatile Approach to ortho-Functionalized Arylphosphine Oxides》.Advanced Synthesis & Catalysis published the findings.Synthetic Route of C2H4I2 The information in the text is summarized as follows:

Alkyldiphenylphosphine oxides typically undergo α-deprotonation with alkyllithium reagents. Here, the lithiation of differentially branched alkyldiphenylphosphine oxides was investigated and a diverse, but predictable reactivity was found. γ-Branched derivatives undergo selective directed ortho-metalation (DoM) using butyllithium and TMEDA as an additive. With decreasing degree of γ-branching α-lithiation becomes predominant. The ortho-phosphinoyllithium intermediates are subject to functionalization and C-C bond forming reactions, thus providing a convenient approach to new phosphine oxides and phosphine-borane complexes, which have a good potential for an approach to new ligands for catalysis. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7Synthetic Route of C2H4I2)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Synthetic Route of C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Recommanded Product: 1,2-DiiodoethaneIn 2019 ,《Stable Cross-Conjugated Tetrathiophene Diradical》 was published in Angewandte Chemie, International Edition. The article was written by Zhang, Cheng; Medina Rivero, Samara; Liu, Wuyue; Casanova, David; Zhu, Xiaozhang; Casado, Juan. The article contains the following contents:

A tetracyano quinoidal tetrathiophene, having a central bi(thieno[3,4-c]pyrrole-4,6-dione) acceptor, has been studied. The recovered aromaticity of the thiophenes produces a diradical species with cross-conjugation between the inter-dicyano and inter-dione acceptor paths. A diradical character of y0=0.61 and a singlet-triplet gap of -2.76 kcal mol-1 were determined Competition between the two cross-conjugated paths enhances the disjointed character of the SOMOs and results in the confinement of the diradical to the mol. center, enabling a thermodn. diradical stabilization featuring a half-life of 262 h. Cross-conjugation effects have been also addressed in the anionic species (up to a radical trianion). In the experiment, the researchers used many compounds, for example, 1,2-Diiodoethane(cas: 624-73-7Recommanded Product: 1,2-Diiodoethane)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Recommanded Product: 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 624-73-7In 2017 ,《Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging》 was published in Bioorganic & Medicinal Chemistry Letters. The article was written by Niida, Ayumu; Sasaki, Shigekazu; Yonemori, Kazuko; Sameshima, Tomoya; Yaguchi, Masahiro; Asami, Taiji; Sakamoto, Kotaro; Kamaura, Masahiro. The article contains the following contents:

A structure-activity relationship study of a K-Ras(G12D) selective inhibitory cyclic peptide, KRpep-2d was performed. Alanine scanning of KRpep-2d focusing on the cyclic moiety showed that Leu7, Ile9, and Asp12 are the key elements for K-Ras(G12D) selective inhibition of KRpep-2d. The cysteine bridging was also examined to identify the stable analog of KRpep-2d under reductive conditions. As a result, the KRpep-2d analog (12) including mono-methylene bridging showed potent K-Ras(G12D) selective inhibition in both the presence and the absence of dithiothreitol. This means that mono-methylene bridging is an effective strategy to obtain a reduction-resistance analog of parent disulfide cyclic peptides. Peptide 12 inhibited proliferation of K-Ras(G12D)-driven cancer cells significantly. These results gave valuable information for further optimization of KRpep-2d to provide novel anti-cancer drug candidates targeting the K-Ras(G12D) mutant. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7Application of 624-73-7) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Application of 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Carrillo, Michael J.; Lin, Wei; Endo, Yasuki published an article in 2021. The article was titled 《Microwave spectrum and iodine nuclear quadrupole coupling constants of 1,1-diiodoethane》, and you may find the article in Journal of Molecular Spectroscopy.Computed Properties of C2H4I2 The information in the text is summarized as follows:

The high resolution rotational spectroscopic observation of 1,1-diiodoethane is investigated using a pulsed jet, cavity Fourier transform microwave (FTMW) spectrometer over the frequency range 11.5-18 GHz for the first time. The rotational constants, the centrifugal distortion constants, the nuclear spin-rotation coupling constants, and the complete tensor components of the nuclear quadrupole coupling for both iodine nuclei have been determined and reported. The fitted rotational constants are A = 4548.320446(47), B = 625.629141(55), C = 558.798939(43) MHz and the nuclear quadrupole coupling constants are χaa = -1089.8125(7), χbb – χcc = -542.3162(13), |χab| = 1215.7505(10), χbc = 340.8983(14), and |χac| = 562.4206(19) MHz. No A-E splittings due to the Me group internal rotation were observed Many dipole-forbidden/elec. quadrupole coupling allowed transitions were observed in the spectrum due to the large iodine quadrupole coupling effect. Quantum chem. calculations were performed at the CCSD(T)/aug-cc-pVTZ-pp level of theory. The calculated rotational constants, centrifugal distortion constants, and hyperfine constants were used to guide the data anal. In the experiment, the researchers used 1,2-Diiodoethane(cas: 624-73-7Computed Properties of C2H4I2)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Computed Properties of C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2016,Fash, David M.; Peer, Cody J.; Li, Zhenwu; Talisman, Ian J.; Hayavi, Sima; Sulzmaier, Florian J.; Ramos, Joe W.; Sourbier, Carole; Neckers, Leonard; Figg, W. Douglas; Beutler, John A.; Chain, William J. published 《Synthesis of a stable and orally bioavailable englerin analogue》.Bioorganic & Medicinal Chemistry Letters published the findings.Quality Control of 1,2-Diiodoethane The information in the text is summarized as follows:

Synthesis of analogs of englerin A with a reduced propensity for hydrolysis of the glycolate moiety led to a compound (I) which possessed the renal cancer cell selectivity of the parent and was orally bioavailable in mice.1,2-Diiodoethane(cas: 624-73-7Quality Control of 1,2-Diiodoethane) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Quality Control of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2016,Fischer, Stefan; Huwyler, Nikolas; Wolfrum, Susanne; Carreira, Erick M. published 《Synthesis and Biological Evaluation of Bromo- and Fluorodanicalipin A》.Angewandte Chemie, International Edition published the findings.Related Products of 624-73-7 The information in the text is summarized as follows:

We disclose the syntheses of (+)-bromodanicalipin A as well as (±)-fluorodanicalipin A. The relative configuration and ground-state conformation in solution of both mols. was secured by J-based configuration anal. which revealed that these are identical to natural danicalipin A. Furthermore, preliminary toxicol. investigations suggest that the adverse effect of danicalipin A may be due to the lipophilicity of the halogens. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7Related Products of 624-73-7)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Related Products of 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com