Category: 624-31-7

In 2019,Nature Chemistry included an article by Xia, Guoqin; Weng, Jiang; Liu, Luoyan; Verma, Pritha; Li, Ziqi; Yu, Jin-Quan. Reference of 1-Iodo-4-methylbenzene. The article was titled 《Reversing conventional site-selectivity in C(sp3)-H bond activation》. The information in the text is summarized as follows:

One of the core barriers to developing C-H activation reactions is the ability to distinguish between multiple C-H bonds that are nearly identical in terms of electronic properties and bond strengths. Through recognition of distance and mol. geometry, remote C(sp2)-H bonds have been selectively activated in the presence of proximate ones. Yet achieving such unconventional site selectivity with C(sp3)-H bonds remains a paramount challenge. Here we report a combination of a simple pyruvic acid-derived directing group and a 2-pyridone ligand that enables the preferential activation of the distal γ-C(sp3)-H bond over the proximate β-C(sp3)-H bonds for a wide range of alc.-derived substrates [e.g., I + Me 4-iodobenzoate → II (52%, + 23% diarylated, after esterification)]. A competition experiment between the five- and six-membered cyclopalladation step, as well as kinetic experiments, demonstrate the feasibility of using geometric strain to reverse the conventional site selectivity in C(sp3)-H activation. The experimental process involved the reaction of 1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Photoinduced Transition-Metal-Free Cross-Coupling of Aryl Halides with H-Phosphonates》 were Zeng, Huiying; Dou, Qian; Li, Chao-Jun. And the article was published in Organic Letters in 2019. Formula: C7H7I The author mentioned the following in the article:

Preparation of arylphosphonates and phosphine oxides ArP(O)X2 (Ar = substituted Ph, naphthyl, biphenyl; X = OMe, OEt, OiPr, aryl) by photoinduced transition-metal- and photosensitizer-free cross-coupling of aryl halides (including Ar-Cl, Ar-Br, and Ar-I) with H-phosphonates (including dialkyl phosphonates and diarylphosphine oxides) is reported. Various functional groups were tolerated, including ester, methoxy, dimethoxy, alkyl, Ph, trifluoromethyl, and heterocyclic compounds This simple and green strategy provides a practical pathway to synthesize arylphosphine oxides. The results came from multiple reactions, including the reaction of 1-Iodo-4-methylbenzene(cas: 624-31-7Formula: C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Formula: C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Electrochemical Fluorocyclization of N-Allylcarboxamides to 2-Oxazolines by Hypervalent Iodine Mediator》 were Haupt, John D.; Berger, Michael; Waldvogel, Siegfried R.. And the article was published in Organic Letters in 2019. Reference of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

A resource saving protocol for the synthesis of 5-fluoromethyl-2-oxazolines by using electrochem. has been realized. Thereby, a hypervalent iodine species I(III) is generated by anodic oxidation in the presence of Et3N·5HF and mediates the cyclization of N-allylcarboxamide to 5-fluoromethyl-2-oxazoline. This method allows application to various substrates furnishing the 2-oxazolines with yields up to 68%. The protocol is easy to conduct under constant current conditions offering a sustainable alternative over conventional reagent-based pathways. The experimental part of the paper was very detailed, including the reaction process of 1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Regioselective Cross-Electrophile Coupling of Epoxides and (Hetero)aryl Iodides via Ni/Ti/Photoredox Catalysis》 was published in ACS Catalysis in 2020. These research results belong to Parasram, Marvin; Shields, Benjamin J.; Ahmad, Omar; Knauber, Thomas; Doyle, Abigail G.. Electric Literature of C7H7I The article mentions the following:

A cross-electrophile coupling reaction of epoxides and (hetero)aryl iodides that operates via the merger of three catalytic cycles involving a Ni-, Ti-, and organic photoredox catalyst has been developed. Three distinct classes of epoxides, styrene oxides, cyclic epoxides, and terminal aliphatic epoxides, underwent coupling in moderate to good yield and high regioselectivity with the use of three different nitrogen-based ligands for Ni under otherwise identical reaction conditions. The mild reaction conditions accommodate a broad scope of abundant and complex coupling partners. Mechanistic studies suggest that when styrene oxides are employed radical intermediates are involved via Ti-radical ring opening of the epoxide. Conversely, for terminal aliphatic epoxides, involvement of an iodohydrin intermediate enables the formation of the unexpected linear product. After reading the article, we found that the author used 1-Iodo-4-methylbenzene(cas: 624-31-7Electric Literature of C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Electric Literature of C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Binuclear Palladium Complex Immobilized on Mesoporous SBA-16: Efficient Heterogeneous Catalyst for the Carbonylative Suzuki Coupling Reaction of Aryl Iodides and Arylboronic Acids Using Cr(CO)6 as Carbonyl Source》 was published in Catalysis Letters in 2020. These research results belong to Niakan, Mahsa; Asadi, Zahra; Emami, Mohammad. Application of 624-31-7 The article mentions the following:

A binuclear palladium complex immobilized on organo-functionalized SBA-16 was prepared and structurally characterized by routine techniques. Characterizations indicated that the mesostructure of SBA-16 was maintained after the immobilization of palladium complex. Then, the prepared nanomaterial was applied as a heterogeneous catalyst in the carbonylative Suzuki coupling reaction of aryl iodides RI with arylboronic acids R1B(OH)2 using Cr(CO)6 as carbonyl source to afford diaryl ketones RC(O)R1 [R = Ph, 4-MeC6H4, 4-ClC6H4, 2-H2NC6H4, etc.; R1 = Ph, 4-EtC6H4, 4-F3CC6H4] in excellent yields. Moreover, the catalyst was readily recovered by filtration and could be reused for seven cycles without losing its structural integrity and catalytic activity. The results came from multiple reactions, including the reaction of 1-Iodo-4-methylbenzene(cas: 624-31-7Application of 624-31-7)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Application of 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Safety of 1-Iodo-4-methylbenzeneIn 2019 ,《A tailored polymeric cationic tag-anionic Pd(II) complex as a catalyst for the low-leaching Heck-Mizoroki coupling in flow and in biomass-derived GVL》 appeared in Green Chemistry. The author of the article were Mahmoudi, Hamed; Valentini, Federica; Ferlin, Francesco; Bivona, Lucia Anna; Anastasiou, Ioannis; Fusaro, Luca; Aprile, Carmela; Marrocchi, Assunta; Vaccaro, Luigi. The article conveys some information:

The [PdCl4]2- palladium complex was immobilized on a polystyrene-type resin loaded with pincer-type imidazolium ionic tag binding sites. The catalytic system (Pd(II)-POLI-TAG) has proved to be highly active in the definition of an efficient protocol for the Heck-Mizoroki coupling reaction under batch and flow conditions. Importantly, it is shown to be highly robust in combination with a safe non-toxic reaction medium, i.e. biomass-derived GVL, since it could be reused for multiple runs without significantly losing its activity.1-Iodo-4-methylbenzene(cas: 624-31-7Safety of 1-Iodo-4-methylbenzene) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Safety of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A》 were Beck, Jordan C.; Lacker, Caitlin R.; Chapman, Lauren M.; Reisman, Sarah E.. And the article was published in Chemical Science in 2019. Application of 624-31-7 The author mentioned the following in the article:

A modular synthesis of enantioenriched polyfunctionalized cyclobutanes I [Ar = 4-MeC6H4, 3-F3CC6H4, 2-fluoro-3-pyridyl, etc.] was developed via Pd-catalyzed C-H arylation of 8-aminoquinolinamide with aryl iodides. The C-H arylation products I were derivatized through subsequent decarboxylative coupling processes. This synthetic strategy enabled a 9-step enantioselective total synthesis of the antiproliferative meroterpenoid (+)-rumphellaone A.1-Iodo-4-methylbenzene(cas: 624-31-7Application of 624-31-7) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application of 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Pd Nanoparticle Fabricated Tetrahydroharman-3-carboxylic Acid Analog Immobilized CoFe2O4 Catalyzed Fast and Expedient C-C Cross and C-S Coupling》 were Tamoradi, Taibeh; Veisi, Hojat; Karmakar, Bikash. And the article was published in ChemistrySelect in 2019. HPLC of Formula: 624-31-7 The author mentioned the following in the article:

A novel Pd nanoparticles anchored tryptophan analog ligand immobilized magnetic CoFe2O4 nanocomposite material was synthesized by post-functionalization approach. The material was thoroughly characterized using several advanced anal. techniques. Thereafter, the catalytic application was carried out in the C-C bond formation reactions via Suzuki and Stille cross coupling. Biphenyl derivatives were prepared in both the reactions with high efficiency and short reaction time. The exploration was further continued in the synthesis of aromatic thioethers by C-S coupling using mol. sulfur and haloarenes. The clean ligand-free protocol, devoid of hazardous chems., excellent yields in short reaction time and the reusability of catalyst for several times were the key factors in the methodol.1-Iodo-4-methylbenzene(cas: 624-31-7HPLC of Formula: 624-31-7) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.HPLC of Formula: 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《PdxCuy decorate hypercrosslinked network: Synthesis and application as efficient catalysts for the reduction of 4-nitrophenol and Suzuki-Miyaura coupling reaction》 were Bi, Jiajun; Dong, Yahao; Zhu, Dajian; Guo, Wen; Meng, Di; Li, Tao. And the article was published in Applied Surface Science in 2019. Application In Synthesis of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

4-Nitrophenol may accumulate in the food chain and cause various fatal diseases. Hence, in order to meet the principle of safety, health and environmental protection, achieving high conversion of 4-nitrophenol with efficient and cheaper method is always in demand. In this aspect, a series of five PdxCuy/Ph-Sa-1 (4:0, 3:1, 2:2, 1:3 and 0:4) catalysts were designed and characterized by FT-IR, TEM, SEM, TGA, AAS, XPS and so on. Furthermore, the catalytic performance of several PdxCuy/Ph-Sa-1 were investigated via 4-nitrophenol reduction and kinetics, where Pd2Cu2/Ph-Sa-1 showed higher catalytic activity than Pd/Ph-Sa-1 with the same Pd content. In particular, Pd/Ph-Sa-1 also exhibited excellent catalytic performance in Suzuki-Miyaura coupling reaction. Linking salen-1 monomer and benzene through Scholl reaction was presented as an effective route to obtain polymeric substrate with low-cost and simple synthesis method. In addition, Pd/Ph-Sa-1 showed desirable recyclability with maintaining its catalytic activity even after five recycles, we also studied the morphol. and Pd state of Pd/Ph-Sa-1 after five recycles by TEM and XPS. This work is highly suggestive on the heterogeneous catalysts design and application. In the experiment, the researchers used 1-Iodo-4-methylbenzene(cas: 624-31-7Application In Synthesis of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application In Synthesis of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《In situ decorated Pd NPs on chitosan-encapsulated Fe3O4/SiO2-NH2 as magnetic catalyst in Suzuki-Miyaura coupling and 4-nitrophenol reduction》 was written by Veisi, Hojat; Ozturk, Turan; Karmakar, Bikash; Tamoradi, Taiebeh; Hemmati, Saba. Quality Control of 1-Iodo-4-methylbenzene And the article was included in Carbohydrate Polymers in 2020. The article conveys some information:

Chitosan is a linear polysaccharide and non-toxic bioactive polymer with a wide variety of applications due to its functional properties such as ease of modification, and biodegradability. In this study, a green protocol for in situ fabrication of ultrafine Pd nanoparticles on chitosan-encapsulated Fe3O4/SiO2-NH2 nanoparticles, without the use of any toxic reducing agents, is described. The catalytic activity of Fe3O4/SiO2-NH2@CS/Pd nanocomposite was investigated through Suzuki-Miyaura coupling to synthesize biaryl derivatives, and reduction of 4-nitrophenol to 4-aminophenol. The core-shell nanoparticle modified with chitosan highly stabilizes the exterior Pd NPs. Leaching test was performed to assure heterogeneity of the catalyst. The magnetically retrievable catalyst was recycled up to eight times in both reactions without significant loss in its activity. In addition to this study using 1-Iodo-4-methylbenzene, there are many other studies that have used 1-Iodo-4-methylbenzene(cas: 624-31-7Quality Control of 1-Iodo-4-methylbenzene) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Quality Control of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com