Category: 619-58-9

Yan, Mao’s team published research in Journal of Photochemistry and Photobiology, A: Chemistry in 2021 | CAS: 619-58-9

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Related Products of 619-58-9

《Effect of triptycene unit on the performance of porphyrin-based dye-sensitized solar cells》 was written by Yan, Mao; Wang, Qun-Hui; Zhu, Yi-Zhou; Han, Ming-Liang; Yan, Yi-Qiao; Zheng, Jian-Yu. Related Products of 619-58-9This research focused ontriptycene porphrin dye sensitized solar cell. The article conveys some information:

Triptycene has been first introduced into porphyrin sensitizers (JY74 and JY75) for dye sensitized solar cells. Compared to reference dye YD26, the homoarom. electron delocalization of triptycene makes the designed dyes a broadened absorption. Meanwhile, the rigid shape-persistent character of triptycene endows JY74 and JY75 an improved ability to diminish the charge recombination between electrolyte and semiconductor TiO2. As a result, after structural modification, larger short-circuit current and higher open-circuit voltage are achieved for dyes JY74 and JY75. The power conversion efficiency of JY75 is increased by 26.8 % compared to that of YD26. Consequently, triptycene may be a promising bulky steric hindrance group for decorating photosensitizer to get an attractive photovoltaic performance.4-Iodobenzoic acid(cas: 619-58-9Related Products of 619-58-9) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Related Products of 619-58-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lee, Chang Heon’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2019 | CAS: 619-58-9

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Recommanded Product: 4-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Recommanded Product: 4-Iodobenzoic acidIn 2019 ,《Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Lee, Chang Heon; Shim, Ha Eun; Song, Lee; Moon, Hi Gyu; Lee, Kyuhong; Yang, Jung Eun; Song, Ha Yeon; Choi, Yong Jun; Choi, Dae Seong; Jeon, Jongho. The article contains the following contents:

As a robust radioanal. method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-I-tagged pyrene analog. Single-photon emission computed tomog. and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity. The experimental process involved the reaction of 4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Recommanded Product: 4-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Harish Chinthal, Chayanna’s team published research in Acta Crystallographica, Section E: Crystallographic Communications in 2020 | CAS: 619-58-9

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Product Details of 619-58-9 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

《Fifteen 4-(2-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in zero, one, two and three dimensions》 was written by Harish Chinthal, Chayanna; Kavitha, Channappa N.; Yathirajan, Hemmige S.; Foro, Sabine; Rathore, Ravindranath S.; Glidewell, Christopher. Product Details of 619-58-9 And the article was included in Acta Crystallographica, Section E: Crystallographic Communications in 2020. The article conveys some information:

Fifteen 4-(2-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. In the isostructural 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N20+·C7H4ClO2- (I) and C11H17N20+·C7H4BrO2- (II), and the 4-iodobenzoate salt C11H17N20+·C7H4IO2- (III), the ions are linked by N-H···O hydrogen bonds, forming centrosym. R44(12) four-ion aggregates; a similar aggregate is formed in the 2-chlorobenzoate salt (V), isomeric with (I). In the 2-fluorobenzoate salt C11H17N2O+·C7H4FO2- (IV), and the isomorphous pair of salts, the 2-bromobenzoate (VI), isomeric with (II) and 2-iodobenzoate (VII), isomeric with (III), N-H···O and C-H···π(arene) interactions link the components into three-dimensional arrays. Four-ion R44(12) aggregates are also found in the 2-methylbenzoate, 4-aminobenzoate and 4-nitrobenzoate salts, C11H17N2O+·C8H7O2- (VIII), C11H17N2O+·C7H6NO2- (IX) and C11H17N2O+·C7H4NO4- (X), but those in (IX) are linked into complex sheets by an addnl. N-H···O hydrogen bond. In the 3,5-dinitrobenzoate salt, C11H17N2O+·C7H3N2O6-·2H2O (XI), N-H···O and O-H···O hydrogen bonds link the components into a complex ribbon structure. In the picrate salt, C11H17N2O+·C6H2N3O7- (XII), the four-ion aggregates are linked into chains of rings by C-H···O hydrogen bonds. In the hydrogen maleate salt, C11H17N2O+·C4H3O4- (XIII), two- and three-center hydrogen bonds link the ions into a ribbon structure while both anions contain very short but asym. O-H···O hydrogen bonds, having O···O distances of 2.4447 (16) and 2.4707 (17) Å. O-H···O Hydrogen bonds link the anions in the hydrogen fumarate salt (XIV), isomeric with (XIII), into chains that are linked into sheets via N-H···O hydrogen bonds. In the hydrogen (2R,3R)-tartrate salt, C11H17N2O+·C4H5O6-·1.698H2O (XV), the anions are linked into sheets by O-H···O hydrogen bonds. Comparisons are made with the structures of some related compounds The experimental process involved the reaction of 4-Iodobenzoic acid(cas: 619-58-9Product Details of 619-58-9)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Product Details of 619-58-9 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shan, Bing’s team published research in Proceedings of the National Academy of Sciences of the United States of America in 2019 | CAS: 619-58-9

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Safety of 4-Iodobenzoic acid

The author of 《Excitation energy-dependent photocurrent switching in a single-molecule photodiode》 were Shan, Bing; Nayak, Animesh; Williams, Olivia F.; Yost, Dillon C.; Polizzi, Nicholas F.; Liu, Yanming; Zhou, Ninghao; Kanai, Yosuke; Moran, Andrew M.; Therien, Michael J.; Meyer, Thomas J.. And the article was published in Proceedings of the National Academy of Sciences of the United States of America in 2019. Safety of 4-Iodobenzoic acid The author mentioned the following in the article:

The direction of electron flow in mol. optoelectronic devices is dictated by charge transfer between a mol. excited state and an underlying conductor or semiconductor. For those devices, controlling the direction and reversibility of electron flow is a major challenge. We describe here a single-mol. photodiode. It is based on an internally conjugated, bichromophoric dyad with chem. linked (porphyrinato)zinc(II) and bis(terpyridyl)ruthenium(II) groups. On nanocrystalline, degenerately doped indium tin oxide electrodes, the dyad exhibits distinct frequency-dependent, charge-transfer characters. Variations in the light source between red-light (∼1.9 eV) and blue-light (∼2.7 eV) excitation for the integrated photodiode result in switching of photocurrents between cathodic and anodic. The origin of the excitation frequency-dependent photocurrents lies in the electronic structure of the chromophore excited states, as shown by the results of theor. calculations, laser flash photolysis, and steady-state spectrophotometric measurements. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Safety of 4-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sep-21 News Sources of common compounds: 619-58-9

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

619-58-9, name is 4-Iodobenzoic acid, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of 4-Iodobenzoic acid

i. 4-Iodobenzyl alcohol. To a solution of 4-iodobenzoic acid (22 g) in tetrahydrofuran (450 mL) was added borane dimethylsulfide complex (35.5 mL, 10M in tetrahydrofuran), and the solution was allowed to stir overnight. The reaction was quenched by addition of methanol, and the solvent was evaporated. The residue was dissolved in ethyl acetate and filtered. The solvent was evaporated to give a solid, which was recrystallized from ether to yield a white solid, which was chromatographed, eluding with ether, to give 4-iodobenzyl alcohol (15.1 g).

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Zeneca Limited; US5521179; (1996); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sources of common compounds: C7H5IO2

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

619-58-9, name is 4-Iodobenzoic acid, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C7H5IO2

i. 4-Iodobenzyl alcohol. To a solution of 4-iodobenzoic acid (22 g) in tetrahydrofuran (450 mL) was added borane dimethylsulfide complex (35.5 mL, 10M in tetrahydrofuran), and the solution was allowed to stir overnight. The reaction was quenched by addition of methanol, and the solvent was evaporated. The residue was dissolved in ethyl acetate and filtered. The solvent was evaporated to give a solid, which was recrystallized from ether to yield a white solid, which was chromatographed, eluding with ether, to give 4-iodobenzyl alcohol (15.1 g).

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Zeneca Limited; US5521179; (1996); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Discovery of 619-58-9

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

Application of 619-58-9, A common heterocyclic compound, 619-58-9, name is 4-Iodobenzoic acid, molecular formula is C7H5IO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To 4-iodobenzoic acid (15.62g, 63mmol, 1.05eq) in dry DMF (6vol, 90ml) was added potassium carbonate (8.7g, 63mmol, 1.05eq) and the suspension was stirred for 10min. Benzyl bromide (10.25g, 7.13ml, 60mmol, 1 eq) was then added over ca. 1 min. and the resulting suspension was stirred at room temperature under nitrogen for 6.25hr. The mixture was partitioned between ether (200ml) and water (200ml). The aqueous phase was extracted with more ether, then the combined organics were washed with water, aqueous lithium chloride, brine, dried and then evaporated to give the title compound as a white crystalline solid after leaving under vacuum (18.38g, 86%). LCMS; tRET = 3.81 min, 70% ES +ve 376, 356 (+ artefact 1.48min. 28%). 1H NMR (400 MHz, DMSOd6) deltappm 7.92 (d, 2H) 7.74 (d, 2H) 7.46 (d, 2H) 7.35 – 7.42 (m, 3H) 5.34 (s, 2H).

The synthetic route of 619-58-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; GLAXO GROUP LIMITED; WO2009/74590; (2009); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Introduction of a new synthetic route about 619-58-9

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference of 619-58-9, A common heterocyclic compound, 619-58-9, name is 4-Iodobenzoic acid, molecular formula is C7H5IO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To a solution of 4-iodobenzoic acid (6 g, 24.19 mmol) in DCM (300 mL) was added 1,1-carbonyldiimidazole (4.3 15 g, 26.61 mmol) at0C. After being stirred at rt for 2h, hydrazine monohydrate (7.26 g, 145.15 mmol) was added and the mixture was stirred at ft for 5h. The mixture was then concentrated under reduced pressure followed by the addition of water to precipitate out the product. The product was collected by filtration and dried under reduced pressure to afford 15-1 (5.2 g, 82%) as an off white solid. LCMS: 263.05 [M+Hjt

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; KALYRA PHARMACEUTICALS, INC.; HUANG, Peter, Qinhua; KAHRAMAN, Mehmet; BUNKER, Kevin, Duane; (194 pag.)WO2018/67512; (2018); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Some tips on 4-Iodobenzoic acid

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzoic acid, other downstream synthetic routes, hurry up and to see.

Reference of 619-58-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 619-58-9, name is 4-Iodobenzoic acid belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

To a test tube containing a magnetic bar was added aryl halide (1.0 mmol), CuCl2 (13.4 mg, 0.1 mmol), KOH (336 mg, 6.0 mmol), ethylene glycol(12 muL, 0.2 mmol), and DMSO/H2O (1.0 mL/0.5 mL). After flushing with argon, the mixture was stirred in a preheated oil bath at 120 C for 24 h. After cooled to ambient temperature, the reaction mixture was distributed in aqueous HCl (5 %) and ethyl acetate. The organic layer was washed with water and brine, dried over anhydrous MgSO4, and concentrated under vacuum. The crude product was further purified by column chromatography (EtOAc/n-Hexane) to provide the phenols.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzoic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Kim, Jihye; Battsengel, Oyunsaikhan; Liu, Yajun; Chae, Junghyun; Bulletin of the Korean Chemical Society; vol. 36; 12; (2015); p. 2833 – 2840;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The important role of 619-58-9

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzoic acid, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 619-58-9, name is 4-Iodobenzoic acid, belongs to iodides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 619-58-9, Recommanded Product: 619-58-9

To a solution of 4-iodobenzoic acid (2.48 g, 10 mmol) in THF (40 mL) under argon were successively added freshly distilled Et3N (20 mL), PdCl2(PPh3)2 (421 mg, 0.6 mmol, 6 mol%), CuI (191 mg, 1.0 mmol, 10 mol%) and trimethylsilylacetylene (2.40 mL, 17 mmol). The mixture was stirred overnight at room temperature, then filtered through a pad of celite. The residue was washed with EtOAc (100 mL) and the organic phase was successively washed with aqueous 1M HCl solution (3 x 30 mL), water (50 mL) and brine (2 x 30 mL). After drying (MgSO4), filtration and concentration under reduced pressure, the crude residue was dissolved in dry CH2Cl2 (20 mL), and chloroacetonitrile (1 mL, 15 mmol) then Et3N (2.70 mL, 20 mmol) were added. The mixture was stirred at room temperature for 2 days, then the solvents were evaporated under reduced pressure. The residue was dissolved in EtOAc (10 mL) and water (20 mL) was added. The layers were separated and the aqueous phase was extracted with EtOAc (2 x 10 mL). The combined organic layers were successively washed with a saturated aqueous NaHCO3 solution and brine, dried over anhydrous MgSO4, filtrered and concentrated under reduced pressure. The crude residue was purified by flash chromatography on silica gel (10% ethyl acetate/cyclohexane) to provide the pure acylcyanohydrin 8m (1.93 g, 75%) as a orange solid.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzoic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Pantin, Mathilde; Bodinier, Florent; Saillour, Jordan; Youssouf, Yassine M.; Boeda, Fabien; Pearson-Long, Morwenna S.M.; Bertus, Philippe; Tetrahedron; vol. 75; 33; (2019); p. 4657 – 4662;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com