Category: 619-58-9

Zhang, Xu; Huang, Yu-Mei; Qin, Hua-Li; Zhang, Baoguo; Rakesh, K. P.; Tang, Haolin published their research in ACS Omega in 2021. The article was titled 《Copper-Promoted Conjugate Addition of Carboxylic Acids to Ethenesulfonyl Fluoride (ESF) for Constructing Aliphatic Sulfonyl Fluorides》.Computed Properties of C7H5IO2 The article contains the following contents:

A CuO-promoted direct hydrocarboxylation of ethenesulfonyl fluoride (ESF) was developed using carboxylic acid as a nucleophile under mild conditions. A variety of mols. containing both ester group and aliphatic sulfonyl fluoride moiety exhibit great potential in medicinal chem. and chem. biol. Furthermore, the modification of the known drugs Ibuprofen and Aspirin was also demonstrated. In addition to this study using 4-Iodobenzoic acid, there are many other studies that have used 4-Iodobenzoic acid(cas: 619-58-9Computed Properties of C7H5IO2) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Computed Properties of C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Cesium Cation Complexation by a Flavin Receptor via Self-Assembly and Deprotonation》 was published in ACS Omega in 2020. These research results belong to Oka, Yoshimi. Application of 619-58-9 The article mentions the following:

This study focuses on the self-assembly of a new flavin compound and its scaffolding function for a Cs+ ion. 7,8-Dimethyl-10-[4′-(methoxycarbonyl)phenyl]-isoalloxazine (FlH-MB) displays self-assembly in a DMSO solution and has strong dependence on the solvent. In the DMSO solution, both the resulting scaffold and the deprotonation of FlH-MB were demonstrated to induce complex formation with a Cs+ ion, which was investigated by UV-vis, 1H NMR, and fluorescence titrations This complex formation involves both Coulombic and cation-π interactions through the Fl- site in an Fl–MB dimer.4-Iodobenzoic acid(cas: 619-58-9Application of 619-58-9) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Application of 619-58-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Shen, Guodong; Lu, Qichao; Wang, Zeyou; Sun, Weiwei; Zhang, Yalin; Huang, Xianqiang; Sun, Manman; Wang, Zhiming published an article in Synthesis. The title of the article was 《Environmentally Friendly and Recyclable CuCl2 -Mediated C-S Bond Coupling Strategy Using DMEDA as Ligand, Base and Solvent》.Safety of 4-Iodobenzoic acid The author mentioned the following in the article:

An environment-friendly, recyclable and economic strategy was developed to synthesize diaryl chalcogenides by the CuCl2-catalyzed C-S bond-formation reaction via iodobenzenes and benzenethiols/1,2-diphenyldisulfanes using N,N’-dimethylethane-1,2-diamine (DMEDA) as ligand, base and solvent. For these reactions, especially the reactions of diiodobenzenes and aminobenzenethiols/disulfanediyldianilines, a range of substrates were compatible and gave the corresponding products in good to excellent yields. Both of the reagents in the catalytic system (CuCl2/DMEDA) were inexpensive, conveniently separable and recyclable for more than five cycles. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Safety of 4-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Design and synthesis of a novel banana-shaped functional molecule via double cross-coupling》 were Yang, Bingchuan; Shen, Guodong; Huang, Xianqiang; Liu, Rutao. And the article was published in Molecules in 2019. Safety of 4-Iodobenzoic acid The author mentioned the following in the article:

A novel banana-shaped mol. using 2,8-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine (Troger’s base) as bent-core was synthesized via double carbon-carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh3)2Cl2 as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by 1H-NMR, 13C-NMR, Fourier transform IR (FT-IR) spectroscopy and mass spectrometry. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Safety of 4-Iodobenzoic acidHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,ACS Catalysis included an article by Trillo, Paz; Adolfsson, Hans. Recommanded Product: 4-Iodobenzoic acid. The article was titled 《Direct Catalytic Reductive N-Alkylation of Amines with Carboxylic Acids: Chemoselective Enamine Formation and further Functionalizations》. The information in the text is summarized as follows:

Direct reductive N-alkylation of secondary amines with carboxylic acids using molybdenum hexacarbonyl (5 mol %) as catalyst and diethoxymethylsilane as reducing agent generate enamines in a straightforward fashion in high yields. The formed enamines are without the need for isolation or purification further reacted with trimethylsilyl cyanide in the same reaction flask to yield α-amino nitriles in good yields. In the optimized reaction conditions equimolar amounts of carboxylic acid and amine are reacted under neat conditions, and a catalytic amount of trifluoroethanol (0.1 mol %) is added along with TMSCN for the cyanation step. The reductive N-alkylation reaction is demonstrated to be highly chemoselective, tolerating a multitude of different functional groups present in the starting carboxylic acids and amines. The reaction is scalable and the generated α-amino nitriles are converted to other useful compounds, e.g., α-amino acids or amino-tetrazoles. In addition, the intermediate enamines are further transformed into triazolines, sulfonylformamidines, pyrimidinediones, and TMS-propargylamines, resp., in high yields under mild reaction conditions. Benzoic acids react with secondary amines under similar conditions to give tertiary amines in high yields, and using this methodol., the biol. active compound Piribedil was isolated in 80% yield in a direct one-pot reaction setup.4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Recommanded Product: 4-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Trifluoromethylation of Benzoic Acids: An Access to Aryl Trifluoromethyl Ketones》 was written by Liu, Xue; Liu, Long; Huang, Tianzeng; Zhang, Jingjing; Tang, Zhi; Li, Chunya; Chen, Tieqiao. Electric Literature of C7H5IO2This research focused ontrifluoromethyl ketone preparation green chem; benzoic acid trifluoromethyltrimethylsilane trifluoromethylation nucleophilic substitution. The article conveys some information:

The trifluoromethylation of benzoic acids with TMSCF3 was achieved through nucleophilic substitution with the use of anhydrides as an in situ activating reagent. Under the reaction conditions, a wide range of carboxylic acids including the bioactive ones worked well, thus providing a facile and efficient method for preparing aryl trifluoromethyl ketones from the readily available starting materials. In the part of experimental materials, we found many familiar compounds, such as 4-Iodobenzoic acid(cas: 619-58-9Electric Literature of C7H5IO2)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Electric Literature of C7H5IO2 In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Formula: C7H5IO2In 2022 ,《Transformation of Thioacids into Carboxylic Acids via a Visible-Light-Promoted Atomic Substitution Process》 was published in Organic Letters. The article was written by Wang, Rui; Xie, Kai-jun; Fu, Qiang; Wu, Min; Pan, Gao-feng; Lou, Da-wei; Liang, Fu-Shun. The article contains the following contents:

A visible-light-promoted at. substitution reaction for transforming thiocacids into carboxylic acids with DMSO as the oxygen source was developed, affording various alkyl and aryl carboxylic acids in over 90% yields. The at. substitution process proceeded smoothly through a photochem. reactivity of the formed hydrogen bonding adduct between thioacids and DMSO. DMSO-involved proton-coupled electron transfer (PCET), and simultaneously generating thiyl and hydroxyl radicals were proposed to be key species for realizing the transformation.4-Iodobenzoic acid(cas: 619-58-9Formula: C7H5IO2) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Huang, Yuanjing; Zhang, Jing published an article in Synthesis. The title of the article was 《Potassium tert-Butoxide Facilitated Amination of Carboxylic Acids with N,N-Dimethylformamide》.Computed Properties of C7H5IO2 The author mentioned the following in the article:

A practical and efficient potassium tert-butoxide (KOtBu)-facilitated amination of carboxylic acids with N,N-dimethylamine was described. In the presence of catalytic amount of KOtBu, a variety of aliphatic and aromatic carboxylic acids were transformed to N,N-dimethylamides using DMF as the dimethylamine reagent with the assistance of trimethylacetic anhydride. The applicability of this protocol was demonstrated by late-stage dimethylamidation of complex drug mols. A plausible reaction mechanism involving KOtBu-facilitated in-situ amine generation from formamide decomposition and anhydride-mediated condensation was proposed on the basis of mechanistic investigations. The results came from multiple reactions, including the reaction of 4-Iodobenzoic acid(cas: 619-58-9Computed Properties of C7H5IO2)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Computed Properties of C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C7H5IO2In 2019 ,《Influence of strong electron donating nature of phenothiazine on A3B- type porphyrin based dye sensitized solar cells》 appeared in Solar Energy. The author of the article were Duvva, Naresh; Prasanthkumar, Seelam; Giribabu, Lingamallu. The article conveys some information:

Structural modifications of porphyrin sensitizers have shown significant impact on incident photon to current generation while applied into dye sensitized solar cells. Nevertheless, various positional alterations of donor/acceptors attached porphyrin dyes reported until now in which A3B based sensitizers received much attention in DSSCs. Herein, we reported A3B type hexyl-phenothiazine appended porphyrins (G10 and G11) utilized as sensitizer with liquid redox electrolyte results the efficiency of 5.4% which is highest performance amongst A3B type sensitizers reported. Optical and electrochem. properties of G10 and G11 suggested that photoinduced intramol. electron transfer mechanism occurred from donor hexyl-phenothiazine to acceptor acetic acid via porphyrin macrocycle. D. functional theory calculations revealed that lowest occupied MO of dyes close to the conduction band of TiO2 facilitates efficient electron injection from dye to nanoparticles. Incident photon to electron conversion efficiency (IPCE) spectra and J-V curve of dyes depict broad band from 350 to 750 nm in the range of >50-55% as a result power conversion efficiency (η) of 5.11-5.40%. Therefore, design of diverse mol. structures pave the way for improved efficiency and durability of photovoltaic devices. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Computed Properties of C7H5IO2)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Computed Properties of C7H5IO2 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Jiang, Kun; Li, Shi-Jun; Liu, Qing-Peng; Yu, Ning; Li, Yu-Lin; Zhou, Yu-Qiang; He, Kui-Cheng; Lin, Jing; Zheng, Ting-Yu; Lang, Jian; Lan, Yu; Wei, Ye published an article in Chemical Science. The title of the article was 《Iminyl radical-triggered relay annulation for the construction of bridged aza-tetracycles bearing four contiguous stereogenic centers》.Recommanded Product: 4-Iodobenzoic acid The author mentioned the following in the article:

An unprecedented, iminyl radical-triggered relay annulation from oxime-derived peresters and azadienes, which showed good substrate scope and functional group compatibility, and could deliver various bridged I [X = CH2, O; R1 = Ph, 4-methylphenyl, 4-methoxyphenyl, etc.] and II [R2 = Ph, 3-methylphenyl, 4-methoxyphenyl; R3 = propan-2-yl, Bu, hexan-2-yl, etc.] with complex mol. topol. and four contiguous stereogenic centers (dr > 19 : 1) in a single operation. This transformation represented the first example of trifunctionalization of iminyl radicals through simultaneous formation of one C-N and two C-C bonds. DFT calculation studies were conducted to obtain an in-depth insight into the reaction pathways, which revealed that the reactions involved an interesting 1,6-hydrogen atom transfer process. In the experiment, the researchers used 4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Recommanded Product: 4-Iodobenzoic acid Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com