Category: 606-55-3

Yang, Eunkyung published the artcileIntegration of Cyanine, Merocyanine and Styryl Dye Motifs with Synthetic Bacteriochlorins, Application In Synthesis of 606-55-3, the publication is Photochemistry and Photobiology (2016), 92(1), 111-125, database is CAplus and MEDLINE.

Understanding the effects of substituents on spectral properties is essential for the rational design of tailored bacteriochlorins for light-harvesting and other applications. Toward this goal, three new bacteriochlorins containing previously unexplored conjugating substituents have been prepared and characterized. The conjugating substituents include two pos. charged species, 2-(N-Et 2-quinolinium)vinyl- (B-1) and 2-(N-Et 4-pyridinium)vinyl- (B-2), and a neutral group, acroleinyl- (B-3); the charged species resemble cyanine (or styryl) dye motifs whereas the neutral unit resembles a merocyanine dye motif. The three bacteriochlorins are examined by static and time-resolved absorption and emission spectroscopy and d. functional theor. calculations B-1 and B-2 have Q_y absorption bathochromically shifted well into the NIR region (822 and 852 nm), farther than B-3 (793 nm) and other 3,13-disubstituted bacteriochlorins studied previously. B-1 and B-2 have broad Q_y absorption and fluorescence features with large peak separation (Stokes shift), low fluorescence yields, and shortened S₁ (Q_y) excited-state lifetimes (∼700 ps and ∼100 ps). More typical spectra and S₁ lifetime (∼2.3 ns) are found for B-3. The combined photophys. and mol.-orbital characteristics suggest the altered spectra and enhanced nonradiative S₁ decay of B-1 and B-2 derive from excited-state configurations in which electron d. is shifted between the macrocycle and the substituents.

Photochemistry and Photobiology published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C10H15ClO3S, Application In Synthesis of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Han, Xiaojing published the artcileA FRET-based ratiometric fluorescent probe to detect cysteine metabolism in mitochondria, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Organic & Biomolecular Chemistry (2020), 18(7), 1487-1492, database is CAplus and MEDLINE.

As an important biothiol in living cells, cysteine is closely related to oxidative damage in living organisms. Sulfite from cysteine metabolism in living cells plays a crucial role in maintaining homeostasis in an organism, and the unbalance of sulfite in vivo would lead to multiple diseases. Thus the development of a new fluorescent probe for cysteine metabolism is needed urgently in mitochondria which are the main place of cysteine metabolism Herein the authors construct a novel targeting mitochondria fluorescent probe CP-K (I) based on the FRET mechanism to visualize sulfite in living MCF-7 cells. Probe CP-K displays a large Stokes shift of 150 nm, a low detection limit (26.3 nM) and “naked eye” detection after the addition of HSO₃^–. Importantly, it is appropriate for imaging the endogenous sulfite from cysteine metabolism in living cells.

Organic & Biomolecular Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Long, Lingliang published the artcileConstruction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction, Application of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Chemical Communications (Cambridge, United Kingdom) (2019), 55(58), 8462-8465, database is CAplus and MEDLINE.

A novel fluorescent probe XQ-1 for selectively detecting ¹O₂ on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to ¹O₂ not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.

Chemical Communications (Cambridge, United Kingdom) published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Application of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yang, Xinyi published the artcileQuinoline-based fluorescent probe for the detection and monitoring of hypochlorous acid in a rheumatoid arthritis model, Quality Control of 606-55-3, the publication is RSC Advances (2021), 11(50), 31656-31662, database is CAplus and MEDLINE.

The development of effective bioanal. methods for the visualization of hypochlorous acid (HOCl) in situ in rheumatoid arthritis (RA) directly contributes to better understanding the roles of HOCl in this disease. In this work, a new quinoline-based fluorescence probe (HQ) has been developed for the detection and visualization of a HOCl-mediated inflammatory response in a RA model. HQ possesses a donor-π-acceptor (D-π-A) structure that was designed by conjugating p-hydroxybenzaldehyde (electron donor) and 1-ethyl-4-methylquinolinium iodide (electron acceptor) through a CC double bond. In the presence of HOCl, oxidation of phenol to benzoquinone led to the red-shift (93 nm) of the adsorption and intense quenching of the fluorescence emission. The proposed response reaction mechanism was verified by high performance liquid chromatog. (HPLC) and high-resolution mass spectroscopy (HRMS) titration anal. The remarkable color changes of the HQ solution from pale yellow to pink enabled the application of HQ-stained chromatog. plates for the “naked-eye” detection of HOCl in real-world water samples. HQ featured high selectivity and sensitivity (6.5 nM), fast response time (<25 s) to HOCl, reliability at different pH (3.0 to 11.5) and low cytotoxicity. HQ’s application in biol. systems was then demonstrated by the monitoring of HOCl-mediated treatment response to RA. This work thus provided a new tool for the detection and imaging of HOCl in inflammatory disorders.

RSC Advances published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C38H74Cl2N2O4, Quality Control of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pandey, Shyam S. published the artcileEffect of extended π-conjugation on photovoltaic performance of dye sensitized solar cells based on unsymmetrical squaraine dyes, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Tetrahedron (2013), 69(12), 2633-2639, database is CAplus.

Aiming toward the far-red to near IR photon harvesting, three new unsym. squaraine dyes bearing direct ring carboxy functionalized indole as an anchoring moiety with varying donor groups with extended π-conjugation have been successfully synthesized and utilized for dye-sensitized solar cell fabrication. Under simulated solar irradiation, dye SQ-8 gave a photoconversion efficiency of 3.3% mainly harvesting photons in the far-red region between 500 and 700 nm. By extending the π-conjugation of the donor moieties in the novel unsym. squaraine dyes, it was possible to extend the light absorption from far-red to near IR wavelength region. In spite of good light absorption up to 900 nm and energetic matching, dye SQ-16 was found to exhibit decreased photon harvesting, which was explained by the enhanced dye aggregation along with its difficulty in facile electron injection as indicated from electronic absorption spectroscopic and d. functional theory calculation results, resp.

Tetrahedron published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shigemitsu, Yasuhiro published the artcileDevelopment of novel functional dye using computed-aided molecular design techniques and its application to reagents for clinical test, etc., Product Details of C12H14IN, the publication is Nagasaki-ken Kogyo Gijutsu Senta Kenkyu Hokoku (2001), 23-33, database is CAplus.

Novel functional cyanine/merocyanine dyes were synthesized using versatile reactivity of nucleophilic reagents, ketenedithioacetals and 4-methylthiomaleimides. Quantum chem. calculations based on the MO method were carried out for light absorption anal. of these dyes. Also, absorption spectra of photochromic spirooxazine compounds showing absorptions in the longer wavelength region were theor. analyzed aiming at the mol. design of new photochromic compounds

Nagasaki-ken Kogyo Gijutsu Senta Kenkyu Hokoku published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C14H10O4, Product Details of C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Linfeng published the artcileNovel Colorimetric Method for Simultaneous Detection and Identification of Multimetal Ions in Water: Sensitivity, Selectivity, and Recognition Mechanism, Quality Control of 606-55-3, the publication is ACS Omega (2019), 4(3), 5915-5922, database is CAplus and MEDLINE.

Accurate recognition and speciation anal. of heavy metal ions in complex hydrol. environments is always a serious challenge. Here, we propose a small mol. based ultrasensitive colorimetric detection strategy, and apply to the accurate detection of Fe²⁺, Fe³⁺, Co²⁺ and Hg²⁺ in groundwater through the specific recognition of multiple ligands for different metals. The detection limits for Hg²⁺, Co²⁺, Fe²⁺ and Fe³⁺ are calculated as 6.51, 0.34, 0.49 and 1.01 ppb, resp., which are far below the drinking water standards and superior to most of the reported colorimetric sensors. The speciation anal. of Fe²⁺/Fe³⁺ also was realized by a 1-step method without complex pretreatment. The speciation and concentration of Fe²⁺ and Fe³⁺ in actual water samples can be accurately identified and monitored. For a visual on-site detection, we developed a simple test strip and applied to visual monitoring of 4 metals with the detection limit estimated by the naked eye as low as ppb-levels. This colorimetric method realizes the rapid, sensitive and portable multiple metal recognition and Fe²⁺/Fe³⁺ speciation anal., displaying great potential for on-site rapid water quality anal.

ACS Omega published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Quality Control of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Xiuli published the artcileNovel mitochondria-targeted and fluorescent DNA alkylation agents with highly selective activity against cancer cells, Quality Control of 606-55-3, the publication is Dyes and Pigments (2019), 107610, database is CAplus.

A series of novel nitrogen mustard-based fluorescent compounds were reported with good mitochondrial targeting ability and DNA alkylation activity. The results indicated that these compounds can be used directly as reporting and imaging agents for gel electrophoresis and flow cytometry without the necessity of addnl. fluorescent tagging agents. Notably, the compound CXL92 displayed highly selective activity against lung cancer cell line A549 with an IC₅₀ value of 0.32 μM compared to normal cell (LO2).

Dyes and Pigments published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Quality Control of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Arsen’ev, V. G. published the artcileAcetals and vinyl ethers of unsaturated aldehydes and ketones in new syntheses of heterocyclic compounds: IX. Ethoxyvinyl-1,3-dioxinyl cations: synthesis and reactions with nucleophiles, Name: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) (1998), 34(12), 1779-1785, database is CAplus.

A new highly reactive ethoxyvinylphenyldioxinyl perchlorate salt I · ClO₄^– was prepared by reaction of dioxinylium perchlorate II · ClO₄^– with excess tri-Et orthoformate in the presence of 16% perchloric acid. The reaction of I · ClO₄^– with electron-rich aromatic and heteroaromatic substrates result in formation of the corresponding aryl(hetaryl)vinyldioxinylium derivatives III · ClO₄^– [R = 4-Me₂NC₆H₄, 2,4-(AcO)₂-1-naphthyl, 2-methyl-3-indolyl]; with compounds possessing an activated methylene group, 1,3-dioxinylidene merocyanines and trimethinecyanines such as IV are formed, and with amines or amides, iminium derivs such as V. Merocyanines such as VI with a chiral center were synthesized for the first time from chiral racemic ethoxyvinyldioxinyl cations.

Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Name: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Zhong’an published the artcileSupramolecular Assembly of Complementary Cyanine Salt J-Aggregates, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Journal of the American Chemical Society (2015), 137(37), 11920-11923, database is CAplus and MEDLINE.

An understanding of structure-property relationships in cyanine dyes is critical for their design and application. Anionic and cationic cyanines can be organized into complementary cyanine salts, offering potential building blocks to modulate their intra/intermol. interactions in the solid state. Here, we demonstrate how the structures of these complementary salts can be tuned to achieve highly ordered J-type supramol. aggregate structures of heptamethine dyes in crystalline solids.

Journal of the American Chemical Society published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com