Category: 606-55-3

Zhou, Fang published the artcileA new red-emitting fluorescence probe for rapid and effective visualization of bisulfite in food samples and live animals, Application In Synthesis of 606-55-3, the publication is Journal of Agricultural and Food Chemistry (2019), 67(15), 4375-4383, database is CAplus and MEDLINE.

The development of new methods for rapid and effective detection of bisulfite (HSO₃^–) in food samples and imaging of HSO₃^– intake in animals is of significant importance due to the key roles of HSO₃^– in food quality assurance and community health. In this work, a new responsive fluorescence probe, EQC, is reported for the quant. detection of HSO₃^– in food samples and visualization of HSO₃^– intake in animals. Upon addition of HSO₃^–, the UV-vis absorption and red emission of EQC were significantly decreased within 120 s. The changes in absorption and emission spectra of EQC were rationalized by theor. computations. The proposed reaction mechanism of EQC with HSO₃^– was confirmed by high-resolution mass spectrometry (HRMS) and spectroscopic titration measurements. EQC has the advantages of high sensitivity, selectivity (a detection limit of 18.1 nM), and fast response toward HSO₃^–, which enable rapid and effective HSO₃^– detection in buffer solution The practical applications of EQC were demonstrated by the detection of HSO₃^– in food samples and the imaging of HSO₃^– intake in live animals.

Journal of Agricultural and Food Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C21H24O8, Application In Synthesis of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shigemitsu, Yasuhiro published the artcileSynthesis and electronic spectra of novel merocyanine dyes bearing a maleimide ring incorporated into the methine chains, Name: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Dyes and Pigments (2003), 56(2), 167-179, database is CAplus.

The present article describes the synthesis of new polymethine dyes with a heterocyclic ring incorporated into the methine chain. 1-Alkyl-2- or 4-methylpyridinium salts and related compounds reacted at the exocyclic double bond with cyano- or methoxycarbonyl heterocycles bearing a methylthio group to give new polymethine dyes in good yield. This reaction occurred by an addition-elimination mechanism, involving nucleophilic attack of cyclic enamines at deficient carbon atoms on the heterocycles followed by elimination of MeSH. The polymethine dyes obtained are red, violet, and blue in color with absorption peaks at 524-614 nm. Semi-empirical as well as ab-initio quantum chem. calculations were used to theor. characterize their π-π absorption maxima in the visible region which plays a decisive role in their color appearances.

Dyes and Pigments published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C13H10O3, Name: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Missailidis, Sotiris published the artcileAntitumor polycyclic acridines. Part 12. Physical and biological properties of 8,13-diethyl-6-methylquino[4,3,2-kl]acridinium iodide: a lead compound in anticancer drug design, Computed Properties of 606-55-3, the publication is Oncology Research (2002), 13(3), 175-189, database is CAplus and MEDLINE.

The biophys. and biol. characterization of 8,13-diethyl-6-methylquino[4,3,2-k1]acridinium iodide (6) is reported. The compound binds to DNA, as measured by UV, fluorescence, and CD studies, and stabilizes the double helix and higher order DNA structures (DNA triplexes and quadruplexes) against thermal denaturation. Unlike many DNA ligands, (6) shows no specificity for binding to specific base pair combinations and does not inhibit topoisomerase I (topo I) or topo II activity. Furthermore, the biol. fingerprint elicited by (6) in in vitro evaluations does not compare with clin. agents of the topo II inhibition class. The compound provokes cell cycle arrest in response to DNA damage and the biol. sequelae are dependent on the p53 status of the cell line. DNA damage by (6) up-regulates p53 and p21^CIP/WAF1 proteins. The unusual structure of (6) and its ease of synthesis in a one-pot reaction are features that are being exploited in the design and development of a new series of G-quadruplex stabilizing telomerase inhibitors. However, although the second-generation compounds that resulted from (6) present strong telomerase inhibition, (6) in itself presents yet a different mode of action, with a strong preference for triplex DNA, sequences often found in a number of genes.

Oncology Research published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Computed Properties of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koraiem, A. I. M. published the artcileStudies on the synthesis and spectral behaviour of polyfunctional heterocycle cyanine dyes, Computed Properties of 606-55-3, the publication is Aswan Science & Technology Bulletin (2002), 22-35, database is CAplus.

Unsym. (sym.) incorporated cyano pyrazolo (pyrazolium) (4,5-d)oxazine (quinoxaline) 6[2(4)] or 3[4(1)] mono- and bis-3,6[4(2)] monomethine and/or substituted cyano pyrazolo(4,5-d)oxazine [quinoxaline-6-imine (one)]-N-bridgehead heterocyclic zero methine cyanine dyes were prepared The new synthesized cyanines were established by elemental and spectral anal. The spectral behavior in the visible absorption region was discussed on the basis of color – structure relationships.

Aswan Science & Technology Bulletin published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Computed Properties of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koraiem, Ahmed I. M. published the artcileOxonium Salts in the Synthesis and Spectral Behavior of Pyrano(pyrylium)-mono methine Cyanine Dyes, Application of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Journal of Heterocyclic Chemistry (2019), 56(6), 1722-1732, database is CAplus.

Pyrano- and pyrylium mono-8[4(1)] and/or 5(6)-[2(4)]methine cyanine dyes (6a-k, 7a-f) were synthesized based on acyclic heterocyclic Schiff bases of pyrolo[3,2-d]pyrazole[oxazole(imidazol-6-one)]-1-ium iodide salts, 5-acetyl-N-aryl[pyrazolinyl(pyridinyl)]pyrolo-[5,4-d]pyrazolin-iodide salts, and/or (anhydro bases) precursors (1a-i, 2a-I, 3a-i, 4a-i, and 5A,Ba-i). The structure of pyrylium-9-chloride and/or iodide and their pyrano(pyrylium)-mono-8[4(1)] and 5(6)[2(4)]methine cyanine dyes was identified by elemental and spectral data. The absorption spectra of some selected dyes were investigated in 95% EtOH, polar (nonpolar) organic solvents and in universal buffer solutions to investigate the optimal conditions for the application of such dyes as photosensitizers.

Journal of Heterocyclic Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Application of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

El-Aal, Reda M. Abd published the artcileSyntheses and electronic absorption spectra of some new penta- and di-methine cyanine dyes, Application In Synthesis of 606-55-3, the publication is Heteroatom Chemistry (1997), 8(3), 259-266, database is CAplus.

The reaction of a ratio of 1 mol of 5-chloro-3-methyl-1-phenylpyrazolo-4-[2(4)-ethylpyridinium]dimethine cyanine or 5-chloro-4-formyl-3-methyl-1-phenylpyrazole(I) with 2 mol of an appropriate 2(4)-heterocyclic quaternary salt afforded novel pentamethine cyanine dyes. Other reactions of I with heterocyclic nitrogen bases, followed by condensation of the quaternary nitrogen salts with methylheterocyclic iodide salts provided the corresponding unsym. dimethine cyanine dyes. The new pentamethine and dimethine cyanine dyes were identified by elemental analyses and IR and ¹H-NMR spectral data. The visible absorption spectra of some selected dyes were investigated in pure and mixed solvents as well as in universal buffer solutions The measure of the variation of absorbance with pH was utilized for the determination of the pK_a values, and these data are discussed.

Heteroatom Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Application In Synthesis of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koraiem, A. I. M. published the artcileOrientation in the synthesis and absorption spectra of 1H-pyrazolo[4,3-d][1,3]oxazole methine cyanine dyes, Quality Control of 606-55-3, the publication is Chemical Papers (1998), 52(6), 762-770, database is CAplus.

3,5-Dimethyl-1-phenyl-1H-pyrazolo[4,3-d][1,3]oxazole was prepared and oriented as starting material in the synthesis of some mono-, di, and trimethine cyanine dyes. The new cyanines were characterized by IR and ¹H NMR spectral data. The visible absorption spectra of the cyanine dyes are discussed.

Chemical Papers published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Quality Control of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koraiem, A. I. M. published the artcileSome new nitrogen bridgehead heterocyclic cyanine dyes, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Chemical Papers (2000), 54(2), 78-86, database is CAplus.

New monomethine, trimethine, and azomethine cyanine dyes of pyrazolo[4′,5′:5,6](pyrazinio/1,4-oxazinio)[2,3,4-i,j]quinolin-11-ium bromides were prepared These cyanines were identified by elemental and spectral analyses. The visible absorption spectra of some selected dyes were investigated in single and mixed solvents, and also in aqueous buffer solutions The spectral shifts are discussed in relation to mol. structure and in terms of medium effects. Mol. complex formation with DMF was verified through mixed-solvent studies.

Chemical Papers published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Safety of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koraiem, A. I. M. published the artcileStudies on some new bridgehead nitrogen heterocyclic cyanine dyes, COA of Formula: C12H14IN, the publication is Proceedings – Indian Academy of Sciences, Chemical Sciences (1999), 111(6), 709-724, database is CAplus.

New asym. mono-(tri)-methine and azomethine cyanine dyes of pyrazolo[5,4-b]quinolino[a,b]-1,4-pyra-(oxa)-zinium bromide salts were prepared The newly synthesized cyanines were identified by elemental and spectral analyses. The visible absorption spectra of some selected dyes were investigated in single and mixed solvents, and also in aqueous buffer solutions The spectral shifts were studied in relation to mol. structure and in terms of medium effects. Mol. complex formation with DMF was verified through mixed-solvent studies.

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, COA of Formula: C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tominaga, Yoshinori published the artcileSynthesis of methylthiomaleimides for the preparation of pyridazines and related compounds, COA of Formula: C12H14IN, the publication is Journal of Heterocyclic Chemistry (2002), 39(3), 571-591, database is CAplus.

New functionalized maleimides [3-(methylthio)-2,5-dioxo-1H-pyrroles] were obtained by the reaction of ketene dithioacetals with nitromethane or the reaction of nitro ketene dithioacetal with active methylene compounds in the presence of the appropriate base in DMSO followed by treatment with methanol. These maleimides reacted with various nucleophilic reagents such as electron-rich aromatic and heteroaromatic compounds like dialkylanilines, aminophenols, indoles, indolizines, and cyclazines to give the corresponding 3-aryl- or -heteroaryl-1H-pyrrole-2,5-diones. Styryl and merocyanine dyes, and polycyclic pyridazinediones as chemiluminophors and succinimides were also obtained from these maleimides with good results.

Journal of Heterocyclic Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C18H23N3O4S, COA of Formula: C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com