Category: 591-18-4

In 2019,Journal of Organic Chemistry included an article by Wisniewski, Steven R.; Savage, Scott A.; Romero, Evan O.; Eastgate, Martin D.; Tan, Yichen; Simmons, Eric M.; Plata, R. Erik; Sowa, John R.; Blackmond, Donna G.. Related Products of 591-18-4. The article was titled 《Utilizing Native Directing Groups: Mechanistic Understanding of a Direct Arylation Leads to Formation of Tetracyclic Heterocycles via Tandem Intermolecular, Intramolecular C-H Activation》. The information in the text is summarized as follows:

A mechanistic study on a direct arylation using a native picolylamine directing group is reported. Kinetic studies determined the concentration dependence of substrates and catalysts, as well as catalyst degradation, which led to the development of a new set of reaction conditions capable of affording a robust kinetic profile. During reaction optimization, a small impurity was observed, which was determined to be a dual C-H activation product. A second set of conditions were found to flip the selectivity of the C-H activation to form this tetracycle in high yield. A catalytic cycle is proposed for the intermol./intramol. C-H activation pathway. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Le Vaillant, Franck; Mateos Calbet, Ana; Gonzalez-Pelayo, Silvia; Reijerse, Edward J.; Ni, Shengyang; Busch, Julia; Cornella, Josep published an article in Nature (London, United Kingdom). The title of the article was 《Catalytic synthesis of phenols with nitrous oxide》.Reference of 1-Bromo-3-iodobenzene The author mentioned the following in the article:

Here, an insertion of N2O into a Ni-C bond under mild conditions (room temperature, 1.5-2 bar N2O) for delivering valuable phenols ROH (R = Ph, 4-cyanophenyl, 1-oxo-2,3-dihydro-1H-inden-4-yl, quinolin-6-yl, etc.) and releasing benign N2 was reported. This fundamentally distinct organometallic C-O bond-forming step differs from the current strategies based on reductive elimination and enables an alternative catalytic approach for the conversion of aryl halides RX (X = I, Br) to phenols. The process was rendered catalytic by means of a bipyridine-based ligands for the Ni center. The method is robust, mild and highly selective, and able to accommodate base-sensitive functionalities as well as permitting phenol synthesis from densely functionalized aryl halides. Although this protocol does not provide a solution to the mitigation of N2O emissions, it represents a reactivity blueprint for the mild revalorization of abundant N2O as an O source. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-iodobenzene(cas: 591-18-4Reference of 1-Bromo-3-iodobenzene)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Reference of 1-Bromo-3-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Descriptor ΔGC-O Enables the Quantitative Design of Spontaneously Blinking Rhodamines for Live-Cell Super-Resolution Imaging》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Chi, Weijie; Qiao, Qinglong; Wang, Chao; Zheng, Jiazhu; Zhou, Wei; Xu, Ning; Wu, Xia; Jiang, Xiao; Tan, Davin; Xu, Zhaochao; Liu, Xiaogang. Related Products of 591-18-4 The article mentions the following:

Herein, we reported a simple, fast, and quant. theor. descriptor ΔGC-O that allows accurate predictions of a wide range of spontaneously blinking rhodamines. ΔGC-O denotes the Gibbs free energy differences between the closed and open forms of rhodamines and has a good linear relationship with exptl. pKcycl values. This correlation affords an effective guide for the quant. designs of spontaneously blinking rhodamines and eliminates trial-and-error. We have validated the predictive power of ΔGC-O via the development of two spontaneously blinking rhodamines of different colors and enhanced brightness. We also demonstrated their super-resolution imaging utilities in dynamic live-cell imaging. We expect that ΔGC-O will greatly facilitate the efficient creations of spontaneously blinking fluorophores and aid the advancements of super-resolution bioimaging techniques. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Experimental and computational evidence on gold-catalyzed regioselective hydration of phthalimido-protected propargylamines: an entry to β-amino ketones》 was written by Marsicano, Vincenzo; Arcadi, Antonio; Aschi, Massimiliano; Michelet, Veronique. Safety of 1-Bromo-3-iodobenzene And the article was included in Organic & Biomolecular Chemistry in 2020. The article conveys some information:

The results of investigations on the Au-catalyzed regioselective hydration reaction of both alkyl- and aryl-substituted N-propargyl phthalimides I (R = CH3, C6H5, 2-thienyl, etc.) directed to the selective formation of the corresponding β-phthalimido ketones II are described. Exptl. data, in particular the observed regioselectivity, have been qual. supported by quantum-chem. calculations carried out on model systems in the framework of D. Functional Theory (DFT) followed by quantum theory of atoms in mols. (QTAIMS). The results suggest that the electronic features of the initial adduct between the propargyl triple bond and the Au(I) catalyst, in particular the character of the gold-triple bond interaction, are essential for the observed regioselectivity. Other effects, such as the presence of the solvent and the formation of a H-bond between the water mol. and the phthalimido moiety, although apparently irrelevant for the regioselectivity, have proven to be kinetically and catalytically rather important.1-Bromo-3-iodobenzene(cas: 591-18-4Safety of 1-Bromo-3-iodobenzene) was used in this study.

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Safety of 1-Bromo-3-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Formula: C6H4BrIIn 2020 ,《Synthesis, Structure, and Optical Properties of Di-m-benzihexaphyrins (1.1.0.0.0.0) and Di-m-benziheptaphyrins (1.0.1.0.0.0.0): Blackening of m-Phenylene-Linked Dicarbaporphyrinoids by Simple π-Expansion》 appeared in Journal of Organic Chemistry. The author of the article were Sulfikarali, Thondikkal; Ajay, Jayaprakash; Suresh, Cherumuttathu H.; Bijina, Padinjare V.; Gokulnath, Sabapathi. The article conveys some information:

Acid catalyzed condensation of newly prepared di-m-benzipentapyrrane with appropriate mono- and diheterocyclic dialcs. selectively produced stable di-m-benzihexaphyrins and di-m-benziheptaphyrins with only two meso-carbon bridges. Single-crystal X-ray diffraction analyses reveal planar conformation with slight distortion of bridged phenylene rings. Despite the presence of m-phenylene units interrupting the global delocalization, the presence of bithiophene unit in di-m-benziheptaphyrins 3a-b exhibit altered optical features covering the entire visible region (∼250-720 nm) exhibiting black dye property as a “”metal-free”” porphyrinoid. After reading the article, we found that the author used 1-Bromo-3-iodobenzene(cas: 591-18-4Formula: C6H4BrI)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Formula: C6H4BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Self-assembly of coordination polyhedra with highly entangled faces induced by metal-acetylene interactions》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Domoto, Yuya; Abe, Masahiro; Kikuchi, Takashi; Fujita, Makoto. HPLC of Formula: 591-18-4 The article mentions the following:

The self-assembly of nanostructures is dominated by a limited number of strong coordination elements. Herein, we show that metal-acetylene π-coordination of a tripodal ligand (L) with acetylene spacers gave an M3L2 double-propeller motif (M=CuI or AgI), which dimerized into an M6L4 interlocked cage (M=CuI). Higher (M3L2)n oligomers were also selectively obtained: an M12L8 truncated tetrahedron (M=CuI) and an M18L12 truncated trigonal prism (M=AgI), both of which contain the same double-propeller motif. The higher oligomers exhibit multiply entangled facial structures that are classified as a trefoil knot and a Solomon link. The inner cavities of the structures encapsulate counter anions, revealing a potential new strategy towards the synthesis of functional hollow structures that is powered by mol. entanglements. The experimental process involved the reaction of 1-Bromo-3-iodobenzene(cas: 591-18-4HPLC of Formula: 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.HPLC of Formula: 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Applied Organometallic Chemistry included an article by Campisciano, Vincenzo; Calabrese, Carla; Liotta, Leonarda Francesca; La Parola, Valeria; Spinella, Alberto; Aprile, Carmela; Gruttadauria, Michelangelo; Giacalone, Francesco. Related Products of 591-18-4. The article was titled 《Templating effect of carbon nanoforms on highly cross-linked imidazolium network: Catalytic activity of the resulting hybrids with Pd nanoparticles》. The information in the text is summarized as follows:

Two different carbon nanoforms (CNFs), namely multi-walled carbon nanotubes (MWCNTs) and carbon nanohorns (CNHs), were chosen as support for the direct polymerization of a bis-vinylimidazolium salt. Transmission electron microscopy analyses revealed a templating effect of the CNFs on the growth of the polymeric network, which perfectly covers their whole surfaces creating a cylindrical or spherical coating for MWCNTs and CNHs, resp. Subsequently, the CNFs-polyimidazolium was used as stabilizers for Pd nanoparticles (Pd NPs), and the obtained materials were characterized by means of anal. and spectroscopic techniques and then employed as easily recoverable and recyclable catalysts for Suzuki and Heck reactions. Quant. conversions was obtained in almost all the explored reactions, even employing low loading of catalyst (down to 0.007 mol%). Suzuki reactions were carried out in pure water under aerobic conditions. Both materials showed excellent activity and recyclability for the investigated C-C coupling reactions, with the CNHs-based material resulting slightly more active than the MWCNTs-based one due to a higher superficial exposure of Pd NPs.1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4) was used in this study.

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 591-18-4In 2021 ,《Single-Handed Double Helix and Spiral Platelet Formed by Racemate of Dissymmetric Cages》 was published in Angewandte Chemie, International Edition. The article was written by Liu, Xiaoning; Shi, Zheng; Xie, Mingchen; Xu, Jianping; Zhou, Zhifan; Jung, Sinyeong; Cui, Guijia; Zuo, Yong; Li, Tao; Yu, Chunyang; Liu, Zhiqiang; Zhang, Shaodong. The article contains the following contents:

Spontaneous deracemization has been used to sep. homochiral domains from the racemic system. However, homochirality can only be referred to when the scales of these domains and systems are specified. To clarify this, we report self-assembly of racemates of dissym. cages DC-1 (I) with a cone-shape propeller geometry, forming a centrosym. columnar crystalline phase (racemic at crystallog. level). Owing to their anisotropic geometry, the two enantiomers are packed in a frustrated fashion in this crystalline phase; single-handed double helixes are observed (single-handedness at supramol. level). The frustrated packing (layer continuity break-up) in turn facilitates screw dislocation during the crystal growth, forming left- or right-handed spiral platelets (symmetry-breaking at morphol. level), although each platelet is composed of DC-1 racemates. The symmetry correlation between DC-1 mols., the crystalline phase and spiral platelets, all exhibit C3 symmetry. In addition to this study using 1-Bromo-3-iodobenzene, there are many other studies that have used 1-Bromo-3-iodobenzene(cas: 591-18-4Application of 591-18-4) was used in this study.

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Application of 591-18-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of C6H4BrIIn 2021 ,《Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles》 was published in Journal of the American Chemical Society. The article was written by Zhang, Pinglu; Tsuji, Nobuya; Ouyang, Jie; List, Benjamin. The article contains the following contents:

An efficient and highly enantioselective catalytic asym. intramol. hydroarylation of aliphatic and aromatic olefins with indoles e.g., 3-(4-methyleneoctyl)-1H-benzo[g]indole yielding tetrahydrocarbazoles e.g., I can be realized using strong and confined IDPi Bronsted acid catalysts. This unprecedented transformation is enabled by tertiary carbocation formation and establishes quaternary stereogenic centers in excellent enantioselectivity and with a broad substrate scope that includes an aliphatic iodide, an azide, and an alkyl boronate, which can be further elaborated into bioactive mols. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-iodobenzene(cas: 591-18-4Electric Literature of C6H4BrI)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Electric Literature of C6H4BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Xiaoshuang; Sun, Lei; Wang, Miaomiao; Maestri, Giovanni; Malacria, Max; Liu, Xiang; Wang, Yanlan; Wu, Lingang published an article in 2022. The article was titled 《C-I Selective Sonogashira and Heck Coupling Reactions Catalyzed by Aromatic Triangular Tri-palladium》, and you may find the article in European Journal of Organic Chemistry.Computed Properties of C6H4BrI The information in the text is summarized as follows:

Aromatic triangular tri-palladium cations, abbreviated as [Pd3]+, have shown interesting photoelec. properties, Lewis basic character, and excellent activities in catalytic hydrogenation. Herein, authors report the highly efficient and C-I selective Sonogashira and Heck coupling reactions catalyzed by these tri-palladium complexes. Benefiting from the moderate C-I bond association energy, these tri-palladiums presented exclusive reactivities to aryl iodides over the brominated aromatics in coupling reactions. In the Sonogashira pathway, good to excellent isolated yields (71-95%) were achieved. Gram-scale reaction reached 93% of yield with palladium loading as few as 0.06 mol %. Authors also explored the electronic and steric effects for Ph alkynes and aryl iodides including heteroaromatics like thiophene, pyridine, pyrazole, and pyrazine. Similarly, yields of 71-96% were obtained for palladium loading of 1.5 mol% through catalyzed Heck coupling of aryl iodides and alkenes. The HRMS monitoring revealed that [Pd3]+ maintained as whole entity during the catalytic process due to its robusness. In addition to this study using 1-Bromo-3-iodobenzene, there are many other studies that have used 1-Bromo-3-iodobenzene(cas: 591-18-4Computed Properties of C6H4BrI) was used in this study.

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Computed Properties of C6H4BrI Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com