Category: 516-12-1

Computed Properties of C4H4INO2In 2020 ,《Efficient Polymer Solar Cells Based on New Random Copolymers with Porphyrin-Incorporated Side Chains》 appeared in Macromolecular Chemistry and Physics. The author of the article were Liu, Zhixin; Huang, Zhuohao; Chen, Yuzhuo; Xu, Tao; Yu, Hao; Guo, Xia; Yan, Lei; Zhang, Maojie; Wong, Wai-Yeung; Wang, Xingzhu. The article conveys some information:

Two new wide bandgap block copolymers (PL1 and PL2) with porphyrin-incorporated side chains are designed and used as electron donors for solution-processed bulk heterojunction polymer solar cells. The photophys., electrochem., and photovoltaic properties, charge transport mobility and film morphol. of these 2 block copolymers are studied. Detailed studies reveal that the different alkyl groups and electron-withdrawing substituents on the porphyrin pendant units have significant influence on the polymer solubility, absorption energy level, band gap, and charge separation in the bulk-heterojunction thin films, and thus the overall photovoltaic performances. Organic photovoltaic devices derived from these copolymers and ([6,6]-phenyl-C71-butyric acid Me ester) (PC71BM) acceptor show the best power conversion efficiencies of 5.83% and 7.14%, resp. The inclusion of a certain proportion of side chain porphyrin group as a pendant in the traditional donor-acceptor (D-A) type polymer can broaden the mol. absorption range and become a full-color absorbing mol. The size of the porphyrin pendant also has an obvious effect on the properties of the mol. The results came from multiple reactions, including the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Computed Properties of C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Computed Properties of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Reaction-based fluorometric analysis of N-bromosuccinimide by oxidative deprotection of dithiane》 were Lee, Yu Jeong; Choi, Myung Gil; Park, Tae Jung; Chang, Suk-Kyu. And the article was published in Analyst (Cambridge, United Kingdom) in 2019. Electric Literature of C4H4INO2 The author mentioned the following in the article:

In this study, a fluorescent probe is developed for the first time for N-bromosuccinimide (NBS), a synthetically and anal. important compound Pyrene-dithiane-based probe 1 showed prominently selective and sensitive signaling behavior toward NBS owing to the oxidative cleavage of the dithiane protecting group of 1-pyrenecarboxaldehyde. The NBS-selective signaling of the probe was possible under competitive conditions in the presence of common metal ions and anions as a background. The detection limit of the probe for NBS was found to be 5.6 × 10-8 M (10.0 ppb). The signaling product was sufficiently stable under the oxidative stress of NBS in contrast to another tested compound, 6-methoxy-2-naphthaldehyde-based dithiane derivative 2, which showed a gradually decaying response because of the reaction of the signaling product with the residual NBS. In the practical application of the probe, a smartphone was used as a stand-alone device, and the fluorometric assays of the com. NBS reagents could be conducted rapidly and in a convenient manner. After reading the article, we found that the author used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Electric Literature of C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Electric Literature of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Intestinal electrogenic sodium-dependent glucose absorption in tilapia and trout reveal species differences in SLC5A-associated kinetic segmental segregation》 were Subramaniam, Marina; Weber, Lynn P.; Loewen, Matthew E.. And the article was published in American Journal of Physiology in 2019. Safety of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Electrogenic sodium-dependent glucose transport along the length of the intestine was compared between the omnivorous Nile tilapia (Oreochromis niloticus) and the carnivorous rainbow trout (Oncorhynchus mykiss) in Ussing chambers. In tilapia, a high-affinity, high-capacity kinetic system accounted for the transport throughout the proximal intestine, midintestine, and hindgut segments. Similar dapagliflozin and phloridzin dihydrate inhibition across all segments support this homogenous high-affinity, high-capacity system throughout the tilapia intestine. Genomic and gene expression anal. supported findings by identifying 10 of the known 12 SLC5A family members, with homogeneous expression throughout the segments with dominant expression of sodium-glucose cotransporter 1 (SGLT1; SLC5A1) and sodium-myoinositol cotransporter 2 (SMIT2; SLC5A11). In contrast, trout’s electrogenic sodium-dependent glucose absorption was 20-35 times lower and segregated into three significantly different kinetic systems found in different anatomical segments: a high-affinity, low-capacity system in the pyloric ceca; a super-high-affinity, low-capacity system in the midgut; and a low-affinity, low-capacity system in the hindgut. Genomic and gene expression anal. found 5 of the known 12 SLC5A family members with dominant expression of SGLT1 (SLC5A1), sodium-glucose cotransporter 2 (SGLT2; SLC5A2), and SMIT2 (SLC5A11) in the pyloric ceca, and only SGLT1 (SLC5A1) in the midgut, accounting for differences in kinetics between the two. The hindgut presented a low-affinity, low-capacity system partially attributed to a decrease in SGLT1 (SLC5A1). Overall, the omnivorous tilapia had a higher electrogenic glucose absorption than the carnivorous trout, represented with different kinetic systems and a greater expression and number of SLC5A orthologs. Fish differ from mammals, having hindgut electrogenic glucose absorption and segment specific transport kinetics. The experimental part of the paper was very detailed, including the reaction process of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 516-12-1In 2020 ,《Synthesis of β-Glucosides with 3-O-Picoloyl-Protected Glycosyl Donors in the Presence of Excess Triflic Acid: A Mechanistic Study》 was published in Chemistry – A European Journal. The article was written by Mannino, Michael P.; Demchenko, Alexei V.. The article contains the following contents:

Our previous study showed that picoloylated donors are capable of providing excellent facial stereoselectivity through the H-bond-mediated aglycon delivery (HAD) pathway. Presented herein is a detailed mechanistic study of stereoselective glycosylation with 3-O-picoloylated glucosyl donors. While reactions of glycosyl donors equipped with the 3-O-benzoyl group are typically non-stereoselective because these reactions proceed via the oxacarbenium intermediate, 3-O-picoloylated donors are capable of providing enhanced, but somewhat relaxed, β-stereoselectivity by the HAD pathway. In an attempt to refine this reaction, we noticed that glycosylations are highly β-stereoselective in the presence of NIS and stoichiometric TfOH. The HAD pathway is highly unlikely because the picoloyl nitrogen is protonated under these reaction conditions. The protonation and glycosylation were studied by low-temperature NMR, and the intermediacy of the glycosyl triflate has been observed This article is dedicated to broadening the scope of this reaction in application to a variety of substrates and targets. After reading the article, we found that the author used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Ex vivo model for elucidating the functional and structural differentiation of the embryonic mouse thyroid》 was written by Carre, Aurore; Gawade, Sanjay; Dertschnig, Simone; Hafen, Kathrin; Polak, Michel; Szinnai, Gabor. Related Products of 516-12-1This research focused onTSH embryonic follicular cell differentiation parathyroid; Culture model; Development; Differentiation; Thyroid. The article conveys some information:

Terminal thyroid gland differentiation – the last developmental step needed to enable thyroid hormone (T4) synthesis – involves profound structural and biochem. changes in the thyroid follicular cells (TFCs). We aimed to develop an ex vivo thyroid model of embryonic mouse thyroid that would replicate the in vivo TFC differentiation program. E13.5 thyroid explants were cultured ex vivo in chem. defined medium for 7 days. Immunostaining and qPCR of thyroid explants showed thyroglobulin production onset, follicle formation, and T4 synthesis onset in 1-, 3-, and 5-day-old cultures, resp. Differentiation was maintained and follicular growth continued throughout the 7-day culture period. Pharmacol. approaches to culture inhibition were performed successfully in the ex vivo thyroids. Our robust and well described ex vivo thyroid culture model replicates the sequence of thyroid differentiation to T4 synthesis seen in vivo. This model can be used to test the effects of pharmacol. inhibitors on thyroid hormone production The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Related Products of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Related Products of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《N-Iodosuccinimide as Bifunctional Reagent in (E)-Selective C(sp2)-H Sulfonylation of Styrenes》 was written by Pramanik, Milan; Choudhuri, Khokan; Mal, Prasenjit. Recommanded Product: 1-Iodopyrrolidine-2,5-dioneThis research focused onvinyl sulfone preparation regioselective stereoselective; styrene sulfonyl hydrazide sulfonylation iodosuccinimide bifunctional reagent. The article conveys some information:

Herein, the use of N-iodosuccinimide (NIS) as a bifunctional reagent for a regio- and (E)-selective C(sp2)-H sulfonylation reaction of styrenes is reported. Styrenes and sulfonyl hydrazides treated with NIS and potassium carbonate in ethanol at 70° resulted in (E)-vinyl sulfones exclusively with good to excellent yields. NIS, plays a dual role to generate sulfonyl radical from sulfonyl hydrazides at an initial stage and finally gives β-iodosulfone intermediate which is further converted to (E)-vinyl sulfones. Overall, a sustainable method for mild, metal free, convenient, one pot and direct synthesis of (E)-vinyl sulfones from styrenes are demonstrated via a C-S coupling reaction. The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging》 was written by De Dominicis, Carlo; Perrotta, Paola; Dall′Angelo, Sergio; Wyffels, Leonie; Staelens, Steven; De Meyer, G. R. Y.; Zanda, Matteo. Name: 1-Iodopyrrolidine-2,5-dione And the article was included in ACS Medicinal Chemistry Letters in 2020. The article conveys some information:

PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and angiogenesis, is an emerging target for diagnosis and therapy of atherosclerosis. The fluorinated phenoxindazole [18F]ZCDD083 was synthesized, radiolabeled in 17 ± 5% radiochem. yield and >99% radiochem. purity, and formulated for preclin. PET/CT imaging in mice. In vivo stability anal. showed no significant metabolite formation. Biodistribution studies showed high blood pool activity and slow hepatobiliary clearance. Significant activity was detected in the lung 2 h postinjection (pi) (11.0 ± 1.5%ID/g), while at 6 h pi no pulmonary background was observed Ex vivo autoradiog. at 6 h pi showed significant high uptake of [18F]ZCDD083 in the arch region and brachiocephalic artery of atherosclerotic mice, and no uptake in control mice, matching plaques distribution seen by lipid staining along with PFKFB3 expression seen by immunofluorescent staining. In vivo PET scans showed higher aortic region uptake of [18F]ZCDD083 in atherosclerotic ApoE-/-Fbn1C1039G+/- than in control mice (0.78 ± 0.05 vs 0.44 ± 0.09%ID/g). [18F]ZCDD083 was detected in aortic arch and brachiocephalic artery of ApoE-/- (with moderate atherosclerosis) and ApoE-/-Fbn1C1039G+/- (with severe, advanced atherosclerosis) mice, suggesting this tracer may be useful for the noninvasive detection of atherosclerotic plaques in vivo. In addition to this study using 1-Iodopyrrolidine-2,5-dione, there are many other studies that have used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Name: 1-Iodopyrrolidine-2,5-dione) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Name: 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Pal, Debasish; Chaudhury, Aritra; Mukhopadhyay, Balaram published an article in European Journal of Organic Chemistry. The title of the article was 《Chemical Synthesis of the Linker-Armed Trisaccharide Repeating Unit of the O-Antigen from Pseudomonas putida BIM B-1100》.Computed Properties of C4H4INO2 The author mentioned the following in the article:

The manuscript reports the concise chem. synthesis of the trisaccharide repeating unit of the O-antigen from Pseudomonas putida BIM B-1100 in the form of its aminoethyl glycoside through a linear strategy with rational protecting group manipulations. The challenging aspects of this synthesis include the incorporation of the β-D-ManpNAcA and the α-D-GlcpNAc residues. The introduction of the desired carboxylic acid moiety has been achieved through late-stage TEMPO-mediated oxidation of the primary OH group on the protected trisaccharide. 1,2-cis aminoethyl glycoside with central glucosamine is used at the reducing end to the leave the scope for further glycoconjugate formation with suitable aglycon without hampering the anomeric stereochem. After reading the article, we found that the author used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Computed Properties of C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Computed Properties of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Beilstein Journal of Organic Chemistry included an article by Frei, Sibylle; Katolik, Adam K.; Leumann, Christian J.. Formula: C4H4INO2. The article was titled 《Synthesis, biophysical properties, and RNase H activity of 6′-difluoro[4.3.0]bicyclo-DNA》. The information in the text is summarized as follows:

Here we present the synthesis, the biophys. properties, and the RNase H profile of 6′-difluorinated [4.3.0]bicyclo-DNA (6′-diF-bc4,3-DNA). The difluorinated thymidine phosphoramidite building block was synthesized starting from an already known gem-difluorinated tricyclic glycal. This tricyclic siloxydifluorocyclopropane was converted into the [4.3.0]bicyclic nucleoside via cyclopropane ring-opening through the addition of an electrophilic iodine during the nucleosidation step followed by reduction The gem-difluorinated bicyclic nucleoside was then converted into the corresponding phosphoramidite building block which was incorporated into oligonucleotides. Thermal denaturation experiments of these oligonucleotides hybridized to complementary DNA or RNA disclosed a significant destabilization of both duplex types (Tm/mod = -1.6 to -5.5°C). However, in the DNA/RNA hybrid the amount of destabilization could be reduced by multiple insertions of the modified unit. In addition, CD spectroscopy of the oligonucleotides hybridized to RNA showed a similar structure than the natural DNA/RNA duplex. Furthermore, since the structural investigation on the nucleoside level by X-ray crystallog. and ab initio calculations pointed to a furanose conformation in the southern region, a RNase H cleavage assay was conducted. This experiment revealed that the oligonucleotide containing five modified units was able to elicit the RNase H-mediated cleavage of the complementary RNA strand. The experimental part of the paper was very detailed, including the reaction process of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Formula: C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Formula: C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Bacterially-assisted recovery of cadmium and nickel as their metal sulfide nanoparticles from spent Ni-Cd battery via hydrometallurgical route》 was published in Journal of Environmental Management in 2020. These research results belong to Paul, Siddhartha; Shakya, Arvind Kumar; Ghosh, Pranab Kumar. Synthetic Route of C4H4INO2 The article mentions the following:

A review. Soaring demand for technol. metals (e.g., Cd, Ni) and its ever-depleting primary resources ask for alternative recovery from secondary sources. Ni-Cd battery is one such source that can abridge the gap between demand and supply of such metals. Biogenic recovery, being environmentally benign, is explored for Cd and Ni recovery to manage the menace of spent Ni-Cd battery. Studies with 20, 40 and 60 mg/L Cd2+ initial concentrations in batch mode (in triplicates) at pH 7.0 ± 0.2, 30 ± 0.5°C and 120 rpm were conducted using sulfate-reducing bacteria for 10 days. Anal. of extracellular polymeric substance revealed that protein secretion was enhanced, thereby forming Cd-EPS binding. Biosolids were collected and freeze-dried for morphol. anal. viz. FESEM/EDX, PXRD and TEM, which revealed the formation of CdS nanoparticles (JCPDS card #00-042-1411) in range of 2-6 nm. Similarly, combined effect with 5, 10 and 20 mg/L Ni2+ at 20 mg/L Cd2+ were also investigated. Furthermore, to test the efficacy for real field application, spent Ni-Cd battery was dismantled and its powder was characterized, digested with concentrated HCl at 70°C and was fed in batch mode after cooling, wherein nanoparticles of Ni and Cd sulfides were formed that has potential as semi-conducting material. In addition to this study using 1-Iodopyrrolidine-2,5-dione, there are many other studies that have used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Synthetic Route of C4H4INO2) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Synthetic Route of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com