Category: 51560-21-5

Related Products of 51560-21-5, These common heterocyclic compound, 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Under nitrogen, the 7.8g 2,5-diiodo-1,4-methoxybenzene was dissolved in 50mL of dichloromethane, and at -78 condition, to the solution was added dropwise 5.58mL three boron bromide. After completion of the dropwise addition, stirred for 16 hours at room temperature, the solid was suction filtered to produce a large number, and dried in vacuo to give a white solid which is 2,5-diiodo-1,4-bis(hydroxy)benzene. Among these, 2,5-diiodo-1,4-di(methoxybenzene, boron tribromide in methylenechloride and the molar ratio of 1: 3:40;

The synthetic route of 51560-21-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shaanxi Normal University; Fang, Yu; Sun, xiaohuan; Cui, Hong; Qi, yanyu; Liu, ke; Wang, Gang; Chang, xingmao; (21 pag.)CN104031108; (2016); B;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 51560-21-5,Some common heterocyclic compound, 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, molecular formula is C8H8I2O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: according to the Mizoroki-Heck reaction (Scheme 1). First; by thecoupling between 4-substituted styrenes and dibromo or diiodobenzenes(Method A, Scheme 1), and second; the reaction between4-substituted bromo or iodobenzenes with 1,4-divinylbenzene(Method B, Scheme 1).The general procedure is as follows: 2.05 equivalents of thecorresponding styrene and 1 equivalent of 1,4-dibromo or 1,4-diiodobenzene (Method A, to OPVs 1a-d and 2a-f) or 2.05 equivalentsof the appropriate aryl halide and 1 equivalent of 1,4-divinylbenzene (Method B, to OPVs 1e-h), were placed in a 10 mLheadspace crimp vial equipped with a magnetic stir bar. Then, forboth methods, it was added 0.01 equivalents (1 mol%) of Pd(dba)2,0.1 equivalents (10 mol%) of P(OPh)3 and 5 equivalents of TEA. Thevial was sealed with a PTFE/silicone septum with aluminum capand purged-saturated with N2, then 2 mL of solvent was injected(dry DMF for OPVs-series 1 and 1,4-dioxane for OPVs-series 2,Scheme 1) and the system was purged once again with N2. Thereaction mixture was vigorously stirred at 110 C during 48 h forOPVs-series 1 and 24 h for OPVs-series 2. After finished, highlyfluorescent solid products were obtained.

The synthetic route of 51560-21-5 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Estrada, Sandra E.; Ochoa-Puentes, Cristian; Sierra, Cesar A.; Journal of Molecular Structure; vol. 1133; (2017); p. 448 – 457;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Some common heterocyclic compound, 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, molecular formula is C8H8I2O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. HPLC of Formula: C8H8I2O2

Under an argon atmosphere, 15.6 g of compound 1 was dissolved in 100 mL of dichloromethane,And 8.18 mL of boron tribromide was added dropwise to the solution at -78 C.Wherein the molar ratio of compound 1, boron tribromide and methylene chloride is 1: 2.2: 40. The reaction was stirred for 16 hours,After completion of the reaction, the reaction solution was transferred to an ice-water mixture and stirred, suction-filtered and dried in vacuo to give a white solid.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 51560-21-5, its application will become more common.

Reference:
Patent; Shaanxi Normal University; Fang, Yu; Qi, Yanyu; Sun, Xiaohuan; Chang, Xingmao; Cui, Hong; He, Meixia; Wang, Gang; (22 pag.)CN104893714; (2016); B;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 51560-21-5

Example 3.3; Synthesis of 2,5-diiodo- 1 ,4-hydroquinone; A solution of 2,5-diiodo- 1,4-dimethoxybenzene (3.0Og, 7.69 mmol) in 30 ml ofAnhydrous dichloromethane was cooled to -80C and BBr3 (19 ml, 16.93 mmol) was added drop wise. The mixture was allowed to rt and stirred for additional 12h, solid precipitate was formed, collected and then crystallized from ethanol-water. The trace of solvent was evaporated at reduced pressure(2.50 g, yield 90 %).

The synthetic route of 51560-21-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; UNIVERSITA’ DEGLI STUDI DI BARI; CONSIGLIO NAZIONALE DELLE RICERCHE; UNIVERSITA’DEGLI STUDI DEL SALENTO; WO2008/96239; (2008); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reference of 51560-21-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: To a 10 mL headspace crimp vial equipped with a magnetic stirrer the corresponding styrene (2.0 mmol), aryl 1,4-dihalide precursor (1.0 mmol), bis(dibenzilidene)acetone palladium (0) (2.0 mol%) and triphenylphosphite (9.0 mol%) were added. The vial was then sealed with a PTFE septum and an aluminum cap followed by purge-saturation with argon. Dry DMF (3 mL) and triethylamine (2.0 mmol) were subsequently added via syringe. The reaction mixture was stirred at 110C for 24 hours. After reaction is complete, the crude was filtered over celite and precipitation of the product was induced by addition of cold water (75 mL). Recrystallization from a 2:1 DMF:1,4-dioxane afforded the desired OPVs.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Diiodo-2,5-dimethoxybenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Acelas, Mauricio; Sierra, Andres Felipe; Sierra, Cesar A.; Synthetic Communications; (2020);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 51560-21-5, The chemical industry reduces the impact on the environment during synthesis 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, I believe this compound will play a more active role in future production and life.

Compound 8 (1.0 g, 2.56 × 10 -3 mol) was dissolved in dichloromethane (20 mL) and stirred in an ice-salt bath for 30 minutes.A 1.0 M solution of BBr3 in dichloromethane (6.14 mL, 6.14 × 10 -3 mol) was added to the solution, and the mixture was stirred overnight.afterwards,After adding deionized water to the reaction mixture until no white smoke is generated,Suction filtration was performed.The obtained solid is dried under vacuum,Compound 9 was obtained as a white solid (yield 0.81 g, 87.1%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Diiodo-2,5-dimethoxybenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Tokyo Denki University; Adachi, Naoya; Nagahori, Tomomi; (27 pag.)JP2020/2024; (2020); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 51560-21-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, This compound has unique chemical properties. The synthetic route is as follows.

To a solution of PdCl2(PPh3)2 (28mg, 0.04mmol), CuI (15.2mg, 0.08mmol), and 2,5-diidodimethoxybenzene (0.78g, 2mmol) in toluene (100ml), was added trimethylsilyacetylene (0.68ml, 4.8mmol) under nitrogen. Triethylamine (0.56ml, 8mmol) was later added dropwise and the reaction mixture was stirred for 24 hours at room temperature. On completion of the reaction (TLC), the solvent was evaporated and the resulting solid residue taken up with dichloromethane. The solution was filtered, concentrated and recrystallized from methanol to give a white-yellowish paste which solidified on standing (0.59g, 90%).

The chemical industry reduces the impact on the environment during synthesis 1,4-Diiodo-2,5-dimethoxybenzene. I believe this compound will play a more active role in future production and life.

Reference:
Article; Tsakama, Madalitso; Shang, Yuting; He, Yonghuang; Fan, Bei; Wang, Fengzhong; Chen, Weihua; Dai, Xiaofeng; Tetrahedron Letters; vol. 57; 16; (2016); p. 1739 – 1742;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 51560-21-5, These common heterocyclic compound, 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Under nitrogen, the 7.8g 2,5-diiodo-1,4-methoxybenzene was dissolved in 50mL of dichloromethane, and at -78 condition, to the solution was added dropwise 5.58mL three boron bromide. After completion of the dropwise addition, stirred for 16 hours at room temperature, the solid was suction filtered to produce a large number, and dried in vacuo to give a white solid which is 2,5-diiodo-1,4-bis(hydroxy)benzene. Among these, 2,5-diiodo-1,4-di(methoxybenzene, boron tribromide in methylenechloride and the molar ratio of 1: 3:40;

The synthetic route of 51560-21-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shaanxi Normal University; Fang, Yu; Sun, xiaohuan; Cui, Hong; Qi, yanyu; Liu, ke; Wang, Gang; Chang, xingmao; (21 pag.)CN104031108; (2016); B;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, A new synthetic method of this compound is introduced below., Product Details of 51560-21-5

The compound was synthesized following the method described in Zhao and Schanze, Chem. Commun 2010, 46, 6075-6077, but using compound 6 as the amine. NMR (CD Cl 3, 300 MHz, 6ppm): 7.14 (s, 2H), 6.55 (br, s, 2H), 4.66 (br, s, 6H), 4.34 (s, 4H), 3.03 (m, 12H), 1.76 (m, 12H), 1.45 (m; 12H), 1.43 (s, 54H). 13C NMR (CDCh, 75 MHz, 5ppm): 166.0, 156.2, 151.7 122.7, 86.5, 79.4, 68.7, 58.9, 40.9, 32.9, 28.7, 24.2. HRMS: (ESI+) m/z calcd for CeoHiiuHNsOie [(M + H)]+ 1447.5732, found 1447.5706.

The synthetic route of 51560-21-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; HUANG, Yun; LI, Zhiliang; SCHANZE, Kirk; RISINGER, April; (42 pag.)WO2019/169169; (2019); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 51560-21-5,Some common heterocyclic compound, 51560-21-5, name is 1,4-Diiodo-2,5-dimethoxybenzene, molecular formula is C8H8I2O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: according to the Mizoroki-Heck reaction (Scheme 1). First; by thecoupling between 4-substituted styrenes and dibromo or diiodobenzenes(Method A, Scheme 1), and second; the reaction between4-substituted bromo or iodobenzenes with 1,4-divinylbenzene(Method B, Scheme 1).The general procedure is as follows: 2.05 equivalents of thecorresponding styrene and 1 equivalent of 1,4-dibromo or 1,4-diiodobenzene (Method A, to OPVs 1a-d and 2a-f) or 2.05 equivalentsof the appropriate aryl halide and 1 equivalent of 1,4-divinylbenzene (Method B, to OPVs 1e-h), were placed in a 10 mLheadspace crimp vial equipped with a magnetic stir bar. Then, forboth methods, it was added 0.01 equivalents (1 mol%) of Pd(dba)2,0.1 equivalents (10 mol%) of P(OPh)3 and 5 equivalents of TEA. Thevial was sealed with a PTFE/silicone septum with aluminum capand purged-saturated with N2, then 2 mL of solvent was injected(dry DMF for OPVs-series 1 and 1,4-dioxane for OPVs-series 2,Scheme 1) and the system was purged once again with N2. Thereaction mixture was vigorously stirred at 110 C during 48 h forOPVs-series 1 and 24 h for OPVs-series 2. After finished, highlyfluorescent solid products were obtained.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,4-Diiodo-2,5-dimethoxybenzene, its application will become more common.

Reference:
Article; Estrada, Sandra E.; Ochoa-Puentes, Cristian; Sierra, Cesar A.; Journal of Molecular Structure; vol. 1133; (2017); p. 448 – 457;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com