Category: 507-63-1

507-63-1, name is Heptadecafluoro-1-iodooctane, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C8F17I

A reaction was conducted in the same manner as in Example 1 except that the perfluoroethyl iodide and the copper catalyst were replaced with 1-iodoperfluorooctane (n-C8F17I) and an organic peroxide, i.e., t-butylperoxyisopropyl monocarbonate (Perbutyl I, manufactured by NOF Corporation), respectively. After cooling the reaction mixture, the reaction product was analyzed by gas chromatography (GC). Table 1 shows the results. TABLE 1 Copper Reaction Ethylene Reaction n-C8F17I catalyst temperature pressure time Conversion g g (wt. % *) C. MPa Min GC % Ex. 2 132 13.4 (10) 80 0.1 105 99.94 Ex. 3 130.8 2.66 (2) 80 0.1 120 99.71 Ex. 4 125.3 2.51 (2) 80 0.55 58 99.89 Ex. 5 155.2 3.11 (2) 120 0.1 56 99.97 Ex. 6 122.5 0.62 (0.5) 120 0.55 40 99.86 Comp. 133.2 0.13 ** 105 0.1-0.2 180 97.7 Ex. 1 * wt. % relative to n-C8F17I ** conducted using t-butylperoxyisopropyl monocarbonate (Perbutyl I) as a catalyst The conversion of each 1-iodoperfluorooctane of Examples 2-6 was more than 99.7%. The selectivity for the resulting ethylene adduct (adduct of one ethylene molecule) was 99.9% or greater in each case.

The synthetic route of 507-63-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Funakoshi, Yoshirou; Miki, Jun; US2005/250966; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthetic Route of 507-63-1,Some common heterocyclic compound, 507-63-1, name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Reactions were conducted in the same manner as in Example 1 except that the perfluoroethyl iodide was replaced with 1-iodoperfluorooctane (n-C8F17I). After cooling the reaction mixtures, the reaction products were analyzed by gas chromatography (GC). Table 1 shows the results.; TABLE 1 Copper Reaction Ethylene Reaction n-C8F17I catalyst temperature pressure time Conversion g g (wt. % *) C. MPa Min GC % Ex. 2 132 13.4 (10) 80 0.1 105 99.94 Ex. 3 130.8 2.66 (2) 80 0.1 120 99.71 Ex. 4 125.3 2.51 (2) 80 0.55 58 99.89 Ex. 5 155.2 3.11 (2) 120 0.1 56 99.97 Ex. 6 122.5 0.62 (0.5) 120 0.55 40 99.86 Comp. 133.2 0.13 ** 105 0.1-0.2 180 97.7 Ex. 1 * wt. % relative to n-C8F17I ** conducted using t-butylperoxyisopropyl monocarbonate (Perbutyl I) as a catalyst The conversion of each 1-iodoperfluorooctane of Examples 2-6 was more than 99.7%. The selectivity for the resulting ethylene adduct (adduct of one ethylene molecule) was 99.9% or greater in each case.

The synthetic route of 507-63-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Funakoshi, Yoshirou; Miki, Jun; US2005/250966; (2005); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chemistry, like all the natural sciences, Name: Heptadecafluoro-1-iodooctane, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is Lin, Weiying, introduce the new discover.

A fluorescence turn-on probe for iodide based on the redox reaction between cupric and iodide

We have Successfully introduced a novel strategy for the rational design of a fluorescence turn-on probe for iodide, which is a notorious fluorescence quencher clue to the heavy atom effect. The strategy is based oil the redox reaction between Cu(2+) and iodide. The probe exhibited a 20-fold fluorescence enhancement ill the presence of 4 equiv. of iodide. The probe developed herein represents the first fluorescence amplified probe for iodide. We believe that it will find interesting use ill environment. (C) 2009 Elsevier B.V. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 507-63-1. Name: Heptadecafluoro-1-iodooctane.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I. In an article, author is Masuyama, Yoshiro,once mentioned of 507-63-1, SDS of cas: 507-63-1.

Aldol reactions of alpha-bromoalkyl phenyl ketones and aldehydes with Tin(IV) iodide and tetrabutylammonium iodide

Aldol reactions of alpha-bromoacetophenone and aldehydes in dichloromethane produced the corresponding E-alpha,beta-unsaturated ketones at 25 degrees C with one equimolar amount of tin(IV) iodide, one equimolar amount of tetrabutylammonium iodide and one equimolar amount of N,N-diisopropylethylamine, and produced the corresponding beta-hydroxy ketones at -80 degrees C with one equimolar amount of tin(IV) iodide and two equimolar amounts of tetrabutylammonium iodide. Using one equimolar amount of tin(IV) iodide and two equimolar amounts of tetrabutylammonium iodide at -80 degrees C in dichloromethane, alpha-bromopropiophenone reacted with aldehydes to afford the corresponding syn-alpha-methyl-beta-hydroxy ketones selectively.

Interested yet? Keep reading other articles of 507-63-1, you can contact me at any time and look forward to more communication. SDS of cas: 507-63-1.

Chemistry is an experimental science, Application In Synthesis of Heptadecafluoro-1-iodooctane, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, belongs to iodides-buliding-blocks compound. In a document, author is Randle, Reese W..

Impact of potassium iodide on thyroidectomy for Graves’ disease: Implications for safety and operative difficulty

Background. Potassium iodide often is prescribed prior to thyroidectomy for Graves’ disease, but the effect of potassium iodide on the ease and safety of thyroidectomy for Graves’ is largely unknown. Methods. We conducted a prospective, cohort study of patients with Graves’ disease undergoing thyroidectomy. For the first 8 months, no patients received potassium iodide; for the next 8 months, potassium iodide was added to the preoperative protocol for all patients. Outcomes included operative difficulty (based on the Thyroidectomy Difficulty Scale) and complications. Results. We included a total of 31 patients in the no potassium iodide group and 28 in the potassium iodide group. According to the Thyroidectomy Difficulty Scale, gland vascularity decreased in the potassium iodide group (mean score 2.6 vs 3.3, P = .04), but there were no differences in friability, fibrosis, or size of the thyroid or in overall difficulty of operation (P = not significant for all). Despite similar operative difficulty, patients prescribed potassium iodide were less likely to experience transient hypoparathyroidism (7% vs 26%, P = .018) and transient hoarseness (0% vs 16%, P = .009) compared with the no potassium iodide group. Conclusion. Potassium iodide administration decreases gland vascularity, but does not change the overall difficulty of thyroidectomy. Preoperative use of potassium iodide solution was, however, associated with less transient hypoparathyroidism and transient hoarseness, suggesting that potassium iodide improves the safety of thyroidectomy for Graves’ disease. (C) 2017 Elsevier Inc. All rights reserved.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 507-63-1. Application In Synthesis of Heptadecafluoro-1-iodooctane.

Chemistry, like all the natural sciences, Formula: C8F17I, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is FANELLI, A, introduce the new discover.

INHIBITION OF IODIDE TRANSPORT IN RAT-THYROID CELLS USING N-SUBSTITUTED ANTHRANILIC ACID-DERIVATIVES

The purpose of this study was to test the effects of chloride channel blockers on iodide uptake in thyroid cells, in the hope of eventually using these blockers to identify and isolate a putative iodide transporter, The chloride channel blockers used in this report are derivatives of N-substituted anthranilic acid and were synthesized using published procedures, For these studies FRTL-5 cells, a line of continuous-growing rat thyroid cells, were used as a model system to study effects on iodide transport. In these cells, there are at least two ways for transmembrane iodide movements, a sodium-dependent influx step and a proposed channel that normally mediates iodide efflux, Two derivatives studied decreased iodide accumulation in FRTL-5 cells, but were found also to lower intracellular pH and ATP levels, To simplify interpretation of the effect of the drugs on iodide transport, we extended the studies using plasma membrane vesicles made from pig thyroid, Iodide entry in these vesicles depended on a sodium gradient and was independent of ATP levels, Iodide transport in plasma membrane vesicles and FRTL-5 cells was measured at 30 sec when the uptake was nearly linear and therefore likely to reflect iodide entry, The uptake was measured using three concentrations of iodide and three of drug. Kinetic analysis of the data described a competitive inhibition by the drugs with a K-i of approximately 250 mu M. In summary, N-substituted anthranilic acid derivatives reversibly inhibit iodide entry in FRTL-5 cells and pig plasma membrane vesicles, Because of their ease of synthesis and modification, these derivatives are potentially useful probes for isolation of the NaI symporter in thyroid.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 507-63-1. Formula: C8F17I.

Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is Heigel, E, introduce the new discover, Safety of Heptadecafluoro-1-iodooctane.

Bis(2-chloro-N-methylpyridinium) iodide triiodide

The title compound, 2C(6)H(7)ClN+I-.I-,(3) Y, crystallizes with undulating layers of chains containing alternate iodide and triiodide anions formed from iodine and the heterocyclic iodide salt.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 507-63-1 is helpful to your research. Safety of Heptadecafluoro-1-iodooctane.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 507-63-1, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Shkadauskene, OP, once mentioned the new application about 507-63-1, Safety of Heptadecafluoro-1-iodooctane.

Determination of iodide using the oxidation of o-dianisidine by chloramine B in acid solutions

A method was developed for the kinetic determination of iodides. The method is based on the promoting effect of iodides on the oxidation of a-dianisidine by Chloramine B in hydrochloric acid solutions. The detection limit of the method is 4 x 10(-4) mu g/mL. It was demonstrated that this method can be employed for the determination of iodides in fresh waters. Iodates and periodates do not interfere with the determination of iodides when both of them are present.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 507-63-1. The above is the message from the blog manager. Safety of Heptadecafluoro-1-iodooctane.

In an article, author is SANCHEZ, V, once mentioned the application of 507-63-1, Quality Control of Heptadecafluoro-1-iodooctane, Name is Heptadecafluoro-1-iodooctane, molecular formula is C8F17I, molecular weight is 545.9629, MDL number is MFCD00001064, category is iodides-buliding-blocks. Now introduce a scientific discovery about this category.

UNEXPECTED COUPLING REACTION OF (F-ALKYL)IODIDES WITH 1-BROMO-1-OCTYNE – ACCESS TO 1-(F-ALKYL)-1-OCTYNES

(F-Alkyl)iodides react with 1-bromo-1-octyne in the presence of a radical initiator [alpha,alpha’-azobis(isobutyronitrile)] to give mainly coupling products, 1-(F-alkyl)-1-octynes.

If you are interested in 507-63-1, you can contact me at any time and look forward to more communication. Quality Control of Heptadecafluoro-1-iodooctane.

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, HPLC of Formula: C8F17I, 507-63-1, Name is Heptadecafluoro-1-iodooctane, SMILES is IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, belongs to iodides-buliding-blocks compound. In a document, author is Luo, Jinhua, introduce the new discover.

Electrochemically triggered iodide-vacancy BiOI film for selective extraction of iodide ion from aqueous solutions

The effective extraction and regeneration of radioactive iodide remains an urgent concern for safe nuclear energy utilization. Herein, we developed a novel electrochemically triggered iodide-vacancy BiOI film, which exhibited excellent I- ion extraction capacity of 328.3 mg.g(-1). Especially, due to the ion vacancy trap effect, the film showed high selectivity towards I- ions in the existence of a large number of competitive anions. Additionally, the electrochemically switched ion extraction (ESIE) process with this iodide-vacancy BiOI film possessed fast extraction kinetics and high stability. More importantly, the trapped I(- )ions were easily desorbed from the film without the secondary pollution during the ESIE process and meanwhile, the iodide-vacancy BiOI film was able to be completely regenerated. It is expected that such an iodide-vacancy BiO film with ESIE could become a promising process for the selective extraction of I- ions from the radioactive water.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 507-63-1. HPLC of Formula: C8F17I.