Category: 455-13-0

Synthetic Route of 455-13-0, A common heterocyclic compound, 455-13-0, name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: To a stirred solution of H2O (5 ml) were added CuI (0.1 mmol, 19 mg), aryl halides (1.0 mmol),nitrogen nucleophiles (1.2 mmol), Cs2CO3 (2 mmol, 651 mg) and L5 (0.1 mmol) were added tothe solution, subsequently the mixture was heated to 100 C under air and stirred for 24 h. Whenthe reaction was finished, the mixture was cooled and partitioned by adding the ethyl acetate (20ml) and water (20 ml). Then, the organic phase was separated and the aqueous phase wasextracted with ethyl acetate (20 ml) twice. The combined organic phases were washed withsaturated brine, dried over Na2SO4, and concentrated in vacuo. Then the crude product waspurified by column chromatography through silica gel, eluting with ethyl acetate/petroleum ethersolvent mixture, to give the pure product.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Zhou, Guoquan; Chen, Wen; Zhang, Shihui; Liu, Xuemin; Yang, Zehui; Ge, Xin; Fan, Hua-Jun; Synlett; vol. 30; 2; (2019); p. 193 – 198;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

These common heterocyclic compound, 455-13-0, name is 4-Iodobenzotrifluoride, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C7H4F3I

General procedure: Et3N (10 mL) and THF (10 mL) were added to 4-methoxyiodobenzene19c (1.05 g, 4.5 mmol), CuI (87 mg, 450 mmol), (Ph3P)2PdCl2(158 mg, 225 mmol) and Na ascorbate (89 mg, 450 mmol) under Ar. The mixturewas stirred at 40C for 30 min. Me3SiCCH (1.03 g, 10.5 mmol) was added and the mixture was stirred at 40C for16 h. The evaporation residue, in CH2Cl2, was washed (water,2 ) and dried. Chromatography(petroleum ether / EtOAc 99:1) gave 20c (909 mg, 99%) as an oil (lit.2oil).

The synthetic route of 4-Iodobenzotrifluoride has been constantly updated, and we look forward to future research findings.

Reference:
Article; Kumpan, Katerina; Nathubhai, Amit; Zhang, Chenlu; Wood, Pauline J.; Lloyd, Matthew D.; Thompson, Andrew S.; Haikarainen, Teemu; Lehtioe, Lari; Threadgill, Michael D.; Bioorganic and Medicinal Chemistry; vol. 23; 13; (2015); p. 3013 – 3032;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 455-13-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 455-13-0, name is 4-Iodobenzotrifluoride belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: To a solution of aryl iodide (10 mmol, 1.0 equiv.) in THF (10 mL, 1.0 M) was added 2-propyn-1-ol (1.24 mL, 1.2 equiv.), diisopropylamine (1.68 mL, 1.2 equiv.), PdCl2(PPh3)2 (0.3 mmol, 3 mol%) andCuI (0.5 mmol, 5 mol%). The resulting solution changed colour from yellow to orange and finallybrown in two minutes. The reaction mixture was heated at 50 C and stirred until completeconsumption of the aryl iodide was observed (tlc, 2 h). After filtering the crude material over a padof silica (5 g) and evaporation of the solvent the crude material (1H-NMR) was purified by silica column chromatography (eluent 10% EtOAc in pentanes, Rf = 0.41). After removal of the volatiles,the desired hydroxyl product was typically isolated as yellow oil with a purity > 98% (by 1H-NMR)and was used directly in the next step. Copies of NMR spectra are provided in the electronicsupplementary information.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Iodobenzotrifluoride, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Donnelly, Kian; Zhang, Huan; Baumann, Marcus; Molecules; vol. 24; 20; (2019);,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, COA of Formula: C7H4F3I, 455-13-0, Name is 4-Iodobenzotrifluoride, SMILES is C1=C(C(F)(F)F)C=CC(=C1)I, belongs to iodides-buliding-blocks compound. In a document, author is Yokota, K, introduce the new discover.

Simultaneous determination of iodide and iodate in seawater by transient isotachophoresis-capillary zone electrophoresis with artificial seawater as the background electrolyte

We developed capillary zone electrophoresis with transient isotachophoresis (lTP) as an on-line concentration procedure for simultaneous determination of iodide and iodate in seawater. The effective mobility of iodide was decreased by addition of 20 mM cetyltrimethylammonium chloride to an artificial seawater background electrolyte so that transient ITP functioned for both iodide and iodate. Limits of detection for iodide and iodate were 4.0 and 5.0 mug/l (as iodine) at a signal-to-noise ratio of 3. Values of the relative standard deviation of peak area, peak height, and migration times for iodide and iodate were 2.9, 1.3, 1.0 and 2.3, 2.1, 1.0%, respectively. The proposed method was applied to simultaneous determination of iodide and iodate in seawater collected at a pond at our university. (C) 2004 Elsevier B.V. All rights reserved.

Interested yet? Read on for other articles about 455-13-0, you can contact me at any time and look forward to more communication. COA of Formula: C7H4F3I.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Recommanded Product: 455-13-0, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I. In an article, author is Takagi, Toshiyuki,once mentioned of 455-13-0.

Indium-mediated radical addition of perfluoroalkyl iodide in water

Reaction of perfluoroalkyl groups with carbon-carbon unsaturated compounds using indium in water proceeded smoothly to provide the addition products in high yields. (C) 2011 Elsevier B.V. All rights reserved.

If you¡¯re interested in learning more about 455-13-0. The above is the message from the blog manager. Recommanded Product: 455-13-0.

455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I, Recommanded Product: 4-Iodobenzotrifluoride, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Derbre, Severine, once mentioned the new application about 455-13-0.

Synthesis and evaluation of photoreactive probes to elucidate iodide efflux in thyrocytes

Four photoreactive analogues of 3-biphenyl-40-yl-5,6-dihydroimidazo[2,1-b]thiazole were prepared and evaluated as iodide sequestering agents in sodium iodide symporter-expressing cells. One of these new photoactivatable compounds retained biological activity and was further radiolabeled with tritium. This compound may provide a useful tool for labeling, purification, and identification of target protein responsible for iodide efflux in thyrocytes. (C) 2008 Elsevier Ltd. All rights reserved.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 455-13-0 help many people in the next few years. Recommanded Product: 4-Iodobenzotrifluoride.

455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I, Recommanded Product: 455-13-0, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Lewcenko, Naomi A., once mentioned the new application about 455-13-0.

Alkylpyrrolidiniumtrialkoxysilyl iodides as organic iodide sources for dye-sensitised solar cells

Two new alkylpyrrolidiniumtriethoxysilyl iodides have been developed as iodide sources for DSSCs; the compound with an undecyl spacer between the siloxane and the pyrrolidinium moieties furnished higher open circuit voltages than the propyl analogue and higher efficiencies at low light intensity.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 455-13-0 help many people in the next few years. Recommanded Product: 455-13-0.

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is , belongs to iodides-buliding-blocks compound. In a document, author is Sawada, Naotaka, Name: 4-Iodobenzotrifluoride.

Efficient copper-catalyzed coupling of aryl iodides and thiobenzoic acid

A highly efficient copper-catalyzed coupling reaction of aryl iodides and thiobenzoic acid, using 10 mol % of copper iodide, 20 mol % of 1, 10-phenanthroline, and (Pr2NEt)-Pr-i in toluene, was developed. This methodology is applicable to a variety of aryl iodides. (c) 2006 Elsevier Ltd. All rights reserved.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 455-13-0, in my other articles. Name: 4-Iodobenzotrifluoride.

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Chow, Kai Ming, once mentioned the application of 455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I, molecular weight is 272.01, MDL number is MFCD00039398, category is iodides-buliding-blocks. Now introduce a scientific discovery about this category, HPLC of Formula: C7H4F3I.

A lady with rapid onset of swollen parotid glands

Iodide mumps can occur after administration of any iodinated contrast media, irrespective of the osmolality of the contrast preparation. This condition is characterized by acute salivary gland swelling shortly after contrast study, presumably secondary to toxic accumulation of iodide in salivary glands with high iodide concentration. In this article, a case of iodide mumps is presented, along with a discussion of vulnerability due to renal impairment, which causes prolongation of the half-life of contrast media. A total of 30 additional cases of iodide mumps published in the English literature were reviewed. Despite the clinical observations that iodide mumps resolved with conservative management, it should be emphasized that recurrence is common if vulnerable patients are subjected to further iodinated contrast media.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 455-13-0, HPLC of Formula: C7H4F3I.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 455-13-0, Name is 4-Iodobenzotrifluoride, molecular formula is C7H4F3I, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Wenzel, A, once mentioned the new application about 455-13-0, Computed Properties of C7H4F3I.

Modulation of iodide uptake by dialkyl phthalate plasticisers in FRTL-5 rat thyroid follicular cells

Plasticisers imparting flexibility to plastics are man-made chemicals abundantly present in the environment. Effects of six different dialkyl phthalates were studied in vitro in the rat thyroid cell line FRTL-5 on their ability to modulate basal iodide uptake mediated by the sodium/iodide symporter (NIS). The present study shows that diisodecyl phthalate (DIDP), dioctyl phthalate (DOP), diisononyl phthalate (DINP) and bis (2-ethylhexyl) phthalate (DEHP) significantly enhance iodide uptake when concentrations in the magnitude between 10(-4) M and 10(-3) M were applied. In this range, these phthalates do not assess toxicity on the cells. Specific inhibiton of NIS demonstrated that enhancement of iodide uptake is due to NIS. In contrast, benzyl butyl phthalate (BBP) also augments iodide uptake at 1 mM but this concentration has just exceeded the toxicity threshold and dibutyl phthalate (BBP), the most toxic compound did not modulate iodide uptake at any concentration applied. As we can deduce from our results, plasticisers are capable of significantly modulating NIS mediated iodide uptake activity. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 455-13-0. The above is the message from the blog manager. Computed Properties of C7H4F3I.