Bakherad, Mohammad’s team published research in Tetrahedron Letters in 2008 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Reference of 1-Chloro-4-iodo-2-nitrobenzene

Reference of 1-Chloro-4-iodo-2-nitrobenzeneOn June 2, 2008, Bakherad, Mohammad; Nasr-Isfahani, Hossein; Keivanloo, Ali; Doostmohammadi, Nesa published an article in Tetrahedron Letters. The article was 《Pd-Cu catalyzed heterocyclization during Sonogashira coupling: synthesis of 2-benzylimidazo[1,2-a]pyridine》. The article mentions the following:

The reaction of 2-amino-1-(2-propynyl)pyridinium bromide with various iodobenzenes, catalyzed by Pd-Cu, leads to the formation of 2-benzylimidazo[1,2-a]pyridines. In the part of experimental materials, we found many familiar compounds, such as 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Reference of 1-Chloro-4-iodo-2-nitrobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad’s team published research in Synthetic Communications in 2009 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene

《Pd-Cu-mediated synthesis of 2-substituted imidazo[1,2-α]pyridines in water》 was published in Synthetic Communications in 2009. These research results belong to Bakherad, Mohammad; Keivanloo, Ali; Hashemi, Mahdieh. Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The article mentions the following:

The reaction of 2-amino-1-(2-propynyl)pyridinium bromide with various iodobenzenes, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant and cesium carbonate as the base, in water, led to the formation of 2-substituted imidazo[1,2-α]pyridines. After reading the article, we found that the author used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad’s team published research in Synthetic Communications in 2010 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 41252-95-3Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

The author of 《Synthesis of 6-benzylimidazo[2,1-b][1,3]thiazole during Sonogashira coupling》 were Bakherad, Mohammad; Keivanloo, Ali; Tajbakhsh, Mahmood; Kamali, Taghi A.. And the article was published in Synthetic Communications in 2010. SDS of cas: 41252-95-3 The author mentioned the following in the article:

The reaction of 2-amino-3-(2-propynyl)-1,3-thiazolium bromide with various iodobenzenes in the presence of palladium catalyst led to the formation of 6-benzylimidazo[2,1-b][1,3]thiazoles.1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3SDS of cas: 41252-95-3) was used in this study.

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.SDS of cas: 41252-95-3Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tasler, Stefan’s team published research in Advanced Synthesis & Catalysis in 2007 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides.COA of Formula: C6H3ClINO2 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

COA of Formula: C6H3ClINO2On October 31, 2007 ,《Applicability aspects of transition metal-catalyzed aromatic amination protocols in medicinal chemistry》 appeared in Advanced Synthesis & Catalysis. The author of the article were Tasler, Stefan; Mies, Jan; Lang, Martin. The article conveys some information:

The application of palladium- and copper-catalyzed reactions for the aromatic amination of pharmacol. relevant scaffolds is investigated. The focus is set on the scope of several protocols for the introduction of amines of broad structural diversity, allowing for the synthesis of numerous derivatives of one biol. hit structure for screening in biol. assay systems. Thus, attaining optimized yields and TONs had not a major priority, most important were practical aspects, that is no further purification and drying of reagents and solvents had to be envisaged, ideally only a few transition metal-based protocols had to be applied for synthesizing structurally diverse compounds in sufficient amounts (several milligrams) for screening without any fine-tuning of conditions and catalytic systems. After reading the article, we found that the author used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3COA of Formula: C6H3ClINO2)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides.COA of Formula: C6H3ClINO2 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Jing-Bo’s team published research in Bioorganic & Medicinal Chemistry in 2018 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Liu, Jing-Bo; Li, Feng-Yun; Dong, Jing-Yue; Li, Yu-Xin; Zhang, Xiu-Lan; Wang, Yuan-Hong; Xiong, Li-Xia; Li, Zheng-Ming published an article in Bioorganic & Medicinal Chemistry. The title of the article was 《Anthranilic diamides derivatives as potential ryanodine receptor modulators: Synthesis, biological evaluation and structure activity relationship》.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The author mentioned the following in the article:

A series of novel anthranilic diamides derivatives (7a-s) containing halogen, trifluoromethyl group and cyano group were designed, synthesized, and characterized by m.p., 1H NMR, 13C NMR and elemental analyses. The bioactivity revealed that most of them showed moderate to excellent activities against oriental armyworm (Mythimna separata) and diamondback moth (Plutella xylostella). Above all, the larvicidal activity of I against oriental armyworm was 100% and 40% at 0.25 and 0.1 mg L-1, comparable to that of the standard chlorantraniliprole (100%, 0.25 mg L-1 and 20%, 0.1 mg L-1). What is more, 7o against diamondback moth displayed 90% insecticidal activity at 0.01 mg L-1, superior to chlorantraniliprole (45%, 0.01 mg L-1). The experiments I on the American cockroach (Periplaneta Americana) heart beating rates (Dorsal vessel) and contractile force were compared with chlorantraniliprole. In addition, I could affect the calcium homeostasis in the central neurons of the third larvae of oriental armyworm, which revealed that the ryanodine receptor is the potential target of I. The d. functional theory (DFT) calculation results revealed the amide bridge, the benzene ring of anthraniloyl moiety and pyrazole ring might play an important role in the insecticidal activity through hydrophobic interactions and π-π conjugations. In the experimental materials used by the author, we found 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad’s team published research in Chinese Journal of Chemistry in 2009 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Recommanded Product: 41252-95-3Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Bakherad, Mohammad; Bahramian, Bahram; Nasr-Isfahani, Hossein; Keivanloo, Ali; Sang, Golnaz published an article on February 28 ,2009. The article was titled 《Polystyrene-supported palladium(II) ethylenediamine complex: A recyclable catalyst for the syntheses of 2-benzylimidazo[2,1-b][1,3]benzothiazoles by Sonogashira reaction》, and you may find the article in Chinese Journal of Chemistry.Recommanded Product: 41252-95-3 The information in the text is summarized as follows:

The polymer-supported palladium(II) ethylenediamine complex was used as a catalyst for the heterocyclization by Sonogashira reaction between aryl iodides and 2-amino-3-(2-propynyl)-1,3-benzothiazolium bromide and could readily be recovered from the reaction medium by a simple filtration and reused without a significant loss in its activity. In addition to this study using 1-Chloro-4-iodo-2-nitrobenzene, there are many other studies that have used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Recommanded Product: 41252-95-3) was used in this study.

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Recommanded Product: 41252-95-3Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Urwyler, Stephan’s team published research in Journal of Medicinal Chemistry in 2009 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Quality Control of 1-Chloro-4-iodo-2-nitrobenzene

《Drug Design, in Vitro Pharmacology, and Structure-Activity Relationships of 3-Acylamino-2-aminopropionic Acid Derivatives, a Novel Class of Partial Agonists at the Glycine Site on the N-Methyl-D-aspartate (NMDA) Receptor Complex》 was written by Urwyler, Stephan; Floersheim, Philipp; Roy, Bernard L.; Koller, Manuel. Quality Control of 1-Chloro-4-iodo-2-nitrobenzene And the article was included in Journal of Medicinal Chemistry on August 27 ,2009. The article conveys some information:

Retaining agonistic activity at the glycine coagonist site of the NMDA receptor in mols. derived from glycine or D-serine has proven to be difficult because in the vicinity of the α-amino acid group little substitution is tolerated. We have solved this problem by replacing the hydroxy group of D-serine with an amido group, thus keeping the hydrogen donor function and allowing for further substitution and exploration of the adjacent space. Heterocyclic substitutions resulted in a series of 3-acylamino-2-aminopropionic acid derivatives, with high affinities in a binding assay for the glycine site. In a functional assay assessing the activation of the glycine site, these compounds displayed a wide range of intrinsic efficacies, from antagonism to a high degree of partial agonism. Structure-activity relationships reveal that lipophilic substituents, presumably filling an addnl. hydrophobic pocket, are accepted by the glycine site, provided that they are separated from the α-amino acid group by a short linker. The experimental process involved the reaction of 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Quality Control of 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Quality Control of 1-Chloro-4-iodo-2-nitrobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Goeker, Hakan’s team published research in Journal of Heterocyclic Chemistry in 2009 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Reference of 1-Chloro-4-iodo-2-nitrobenzene

Reference of 1-Chloro-4-iodo-2-nitrobenzeneOn September 30, 2009 ,《Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles》 was published in Journal of Heterocyclic Chemistry. The article was written by Goeker, Hakan; Alp, Mehmet; Ates-Alagoez, Zeynep; Yildiz, Sulhiye. The article contains the following contents:

A series of 47 novel N1-alkylated-2-aryl-5(6)-substituted-1H-benzimidazoles and their three novel indole analogs were synthesized and evaluated for in vitro antifungal activities against Candida species by the tube dilution method. The results showed that I and II, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25-3.12 μg/mL. Indole analogs III (R1 = H, R2 = Br; R1 = Pr, R2 = Br, CN) have no inhibitory activity. The results came from multiple reactions, including the reaction of 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Reference of 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Reference of 1-Chloro-4-iodo-2-nitrobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad’s team published research in Letters in Organic Chemistry in 2011 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Product Details of 41252-95-3

Bakherad, Mohammad; Keivanloo, Ali; Mohammadi, Marzieh; Jajarmi, Saeideh published an article in Letters in Organic Chemistry. The title of the article was 《Syntheses of 2-benzyl substituted imidazo[1,2-a]pyrimidines via coupling-cyclization under Pd-Cu catalysis》.Product Details of 41252-95-3 The author mentioned the following in the article:

The reaction of 1-(prop-2-yn-1-yl)pyrimidin-2(1H)-imine with various halobenzenes in the presence of a palladium catalyst leads to the production of 2-benzyl substituted imidazo[1,2-a]pyrimidines, e.g. I (R = 4-O2N, 2-O2N-4-Cl, 4-MeCO).1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Product Details of 41252-95-3) was used in this study.

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Product Details of 41252-95-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rezaeimanesh, Fatemeh’s team published research in Journal of Chemical Research in 2019 | CAS: 41252-95-3

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Computed Properties of C6H3ClINO2

Computed Properties of C6H3ClINO2On September 30, 2019 ,《Sonogashira coupling reactions: Synthesis of 4-substituted-6-methyl-2-(methylthio)pyrimidines catalyzed by Pd-Cu》 was published in Journal of Chemical Research. The article was written by Rezaeimanesh, Fatemeh; Bakherad, Mohammad; Nasr-Isfahani, Hossein. The article contains the following contents:

An efficient method was developed for the synthesis of 4-(3-arylprop-2-ynyloxy)-6-methyl-2-(methylthio)pyrimidines via palladium-catalyzed Sonogashira reactions of 4-methyl-2-(methylthio)-6-(prop-2-yn-1-yloxy)pyrimidine with electron-poor aryl iodides in acetonitrile at room temperature Excellent yields of the products were obtained in reaction times of 9-11 h. In the part of experimental materials, we found many familiar compounds, such as 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Computed Properties of C6H3ClINO2)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Computed Properties of C6H3ClINO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com