Category: 31253-08-4

Zhang, Ting-Ting published the artcileElectrochemical Alkoxyhalogenation of Alkenes with Organohalides as the Halide Sources via Dehalogenation, Quality Control of 31253-08-4, the publication is Organic Letters (2020), 22(18), 7250-7254, database is CAplus and MEDLINE.

A general, ideal atom use electrochem. technol. to enable alkene alkoxyhalogenation and organohalide dehalogenation in one pot is presented. This technol. is highlighted by convergent strategy integrating several reactions, such as alkene alkoxyhalogenation, organohalide dehalogenation, and dehalogenation deuteration. Exptl. data suggest that alkenes have the lowest oxidation potential, which lead to anodic conversion of the C=C bond to the radical cation intermediates, and cathodic transformations of organohalides, including alkyl and aryl halides, as the nucleophilic halogen sources.

Organic Letters published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C7H7BClFO3, Quality Control of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Jurgen O. published the artcileRadical additions of alkyl 2-haloalkanoates and 2-haloalkanenitriles to alkenes initiated by electron transfer from copper in solvent-free systems, COA of Formula: C5H9IO2, the publication is Liebigs Annalen/Recueil (1997), 2303-2313, database is CAplus.

Alkyl 2-iodoalkanoates and 2-iodoalkanenitriles were added with Cu powder to the 1-alkenes RCH₂CH:CH₂ [R = (CH₂)₇CO₂Me, (CH₂)₄Me, OH, C(CO₂Et)₂CH₂CH:CH₂] and to the alkenes (Z)-R(CH₂)₂CH:CH(CH₂)₂R¹ [R = (CH₂)₅Me, R¹ = (CH₂)₅CO₂Me; R = (CH₂)₅Me, R¹ = (CH₂)₉CO₂Me; R = (CH₂)₈Me, R¹ = (CH₂)₂CO₂Me; RR¹ = bond] to give γ-lactones and 4-iodoalkanenitriles, resp., in very good yields. No solvent was used. The reaction is a free-radical addition initiated by electron transfer from Cu to the activated iodoalkane. Yields were lower using the resp. bromo compounds In-situ formation of the iodo compounds by addition of stoichiometric amounts of NaI to the reaction mixture gave improved yields. In the case of bromomalonates, the addition of NaI proved to be unnecessary. The diastereoselectivity of the addition reaction by relative 1,3-asym. induction was rationalized by consideration of the steric interactions of the substituents in the transition state which is formed in the process of I transfer to the chiral adduct radical.

Liebigs Annalen/Recueil published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, COA of Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Juergen O. published the artcileRadical additions of activated haloalkanes to alkenes initiated by electron transfer from copper in solvent-free systems, Product Details of C5H9IO2, the publication is Angewandte Chemie, International Edition in English (1995), 34(8), 902-4, database is CAplus.

The solventless first radical addition of alkyl α-iodocarboxylates or α-iodoalkanenitriles to alkenes over copper metal involves an electron transfer initiated mechanism. The synthetic utility of this method is discussed.

Angewandte Chemie, International Edition in English published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Product Details of C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Ting-Ting published the artcileElectrochemical Alkoxyhalogenation of Alkenes with Organohalides as the Halide Sources via Dehalogenation, Quality Control of 31253-08-4, the publication is Organic Letters (2020), 22(18), 7250-7254, database is CAplus and MEDLINE.

A general, ideal atom use electrochem. technol. to enable alkene alkoxyhalogenation and organohalide dehalogenation in one pot is presented. This technol. is highlighted by convergent strategy integrating several reactions, such as alkene alkoxyhalogenation, organohalide dehalogenation, and dehalogenation deuteration. Exptl. data suggest that alkenes have the lowest oxidation potential, which lead to anodic conversion of the C=C bond to the radical cation intermediates, and cathodic transformations of organohalides, including alkyl and aryl halides, as the nucleophilic halogen sources.

Organic Letters published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C7H7BClFO3, Quality Control of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lee, Jin Young published the artcileRadical alkylations of alkyl halides and unactivated C-H bonds using vinyl triflates, Computed Properties of 31253-08-4, the publication is Synlett (2010), 1647-1650, database is CAplus.

Radical alkylations of activated alkyl iodides and bromides were achieved using vinyl triflates in the presence of hexadimethyltin, whereas those of unactivated C-H bonds using vinyl triflates proceeded cleanly under tin-free conditions.

Synlett published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Computed Properties of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Deng, Weili published the artcileIron-Catalyzed Carboiodination of Alkynes, HPLC of Formula: 31253-08-4, the publication is Synthesis (2018), 50(15), 2974-2980, database is CAplus.

An iron-catalyzed carboiodination of alkynes/aliphatic alkenes with alkyl iodides at room temperature was developed to afford vinyl iodides I [R¹ = Ac, CO₂Et, Ph, etc.; R² = CH₂CN, CF₂CO₂Et, cyclohexyl, etc.] and secondary alkyl iodides II [R³ = n-hexyl, Bn, 4-FC₆H₄CH₂, CH₂CH₂Ph; R⁴ = CF₂CF₃, CF₂CO₂Et, FCH(CF₃)₂] resp. This method could provided synthetically useful vinyl iodides with general alkyl chains, fluoroalkyl group, ester and cyano group. Conjugated alkynes or unconjugated alkynes were both suitable for this transformation. A radical pathway was proposed for the mechanism and acetyl tert-Bu peroxide was selected as the radical initiator. Alkenes could also be applied to this chem. and produce more complex alkyl iodides.

Synthesis published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, HPLC of Formula: 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Garcia-Dominguez, Andres published the artcileNickel-Catalyzed Reductive Dicarbofunctionalization of Alkenes, HPLC of Formula: 31253-08-4, the publication is Journal of the American Chemical Society (2017), 139(20), 6835-6838, database is CAplus and MEDLINE.

In the presence of tetrapyridinenickel dichloride and 4,4′-di-tert-butyl-2,2′-bipyridine, functionalized alkenes such as allyl acetate underwent regioselective and diastereoselective three-component addition and dicarbofunctionalization reactions with aryl iodides such as RI [R = 4-t-BuC₆H₄, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 3-MeOC₆H₄, 3-MeO₂CC₆H₄, 3-F₃CC₆H₄, 3-BrC₆H₄, 3,5-(F₃C)₂C₆H₃, 4-Br-3-MeOC₆H₃, 3-Cl-5-MeO₂CC₆H₃] and tertiary alkyl iodides such as t-BuI mediated by the organic reductant tetrakis(dimethylamino)ethylene (TDAE) to yield functionalized aryl alkanes such as t-BuCH₂CHRCH₂OAc [R = 4-t-BuC₆H₄, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 3-MeOC₆H₄, 3-MeO₂CC₆H₄, 3-F₃CC₆H₄, 3-BrC₆H₄, 3,5-(F₃C)₂C₆H₃, 4-Br-3-MeOC₆H₃, 3-Cl-5-MeO₂CC₆H₃] in 29-92% yields.

Journal of the American Chemical Society published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, HPLC of Formula: 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kim, Sunggak published the artcileRadical-mediated γ-functionalizations of α,β-unsaturated carboxylic amides, Category: iodides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2004), 43(40), 5378-5380, database is CAplus and MEDLINE.

Highly successful tin-free, radical-mediated alkylations of α,β-unsaturated carboxylic amides have been carried out. Alkyl iodides and bromides bearing α-electron-withdrawing groups undergo selective γ-additions to diene O,N-acetals. This approach to γ-functionalization was further extended to the use of hetero groups, such as phenylsulfanyl and phenylsulfonyl species.

Angewandte Chemie, International Edition published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Category: iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Hao published the artcileDesign, Synthesis and Herbicidal Activities of Tetrahydroisoindoline-1,3-dione Derivatives Containing Alkoxycarbonyl Substituted 2-Benzoxazolinone, Application of Ethyl 2-Iodopropionate, the publication is Chinese Journal of Chemistry (2015), 33(7), 749-755, database is CAplus.

Several different alkoxycarbonyl-substituted 2-benzoxazolinone moieties were incorporated into a tetrahydroisoindoline-1,3-dione scaffold to provide 25 compounds (1,3-dioxo-4,5,6,7-tetrahydroisoindol-2(3H)-yl)-6-halo-alkoxycarbonyl benzoxazolinones e.g., I. The structures of these compounds were confirmed by ¹H and ¹³C NMR, HRMS and X-ray single-crystal diffraction. Some of these compounds I [R = Me propanoate, Et propanoate, ethyl-2-butanoate, ethyl-4-butanoate] exhibited excellent herbicidal activities against Abutilon theophrasti, Amaranthus retroflexus and Echinochloa crus-galli at a rate of 375 g AI·ha^-1. Among them, compounds I [R = Et propanoate, ethyl-2-butanoate] displayed the best post-emergence herbicidal effect against Abutilon theophrasti with ED₅₀ values of 1.8 and 5.3 g AI·ha^-1, resp., which are superior to that of the com. acifluorfen (44.3 g AI·ha^-1). Field trials demonstrated that compound I [R = Et propanoate] exhibited similar herbicidal activity to a high concentration atrazine, and found to be safer for maize than atrazine. The results of this study therefore show that compound I [R = Et propanoate] could potentially be used as a post-emergence herbicide for maize fields.

Chinese Journal of Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C15H14BNO4S, Application of Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhou, Zheng-Xin published the artcileCooperative Ligand-Promoted P(III)-Directed Ruthenium-Catalyzed Remote Meta-C-H Alkylation of Tertiary Phosphines, Formula: C5H9IO2, the publication is Organic Letters (2021), 23(6), 2057-2062, database is CAplus and MEDLINE.

Herein, the authors disclose a Ru-catalyzed meta-selective C-H activation of phosphines by using intrinsic P(III) as a directing group. 2,2,6,6-Tetramethylheptane-3,5-dione acts as the ligand and exhibits an excellent performance in boosting the meta-alkylation. The protocol allows an efficient and straightforward synthesis of meta-alkylated tertiary phosphines. Several meta-alkylated phosphines were evaluated for Pd-catalyzed Suzuki coupling and are superior to com. available ortho-substituted phosphines. The practicability of this methodol. is further demonstrated by the synthesis of difunctionalized phosphines.

Organic Letters published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C6H10F3NO, Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com