Category: 21969-05-1

Compounds of the type C₆H₅XC₆H₅. I. Electric dipole moments of some 4-substituted 4′-nitrodiphenyl ether and di-phenyl sulfide derivatives was written by Rolla, Mario;Sanesi, Manlio. And the article was included in Ric. Sci. Rend. in 1961.Reference of 21969-05-1 The following contents are mentioned in the article:

Elec. dipole moments of derivatives of Ph₂O and Ph₂S were measured in a benzene solution at 20°. The compounds and results (in Debyes) were for Ph₂O: 4-CH₃-4′-NO₂ (4.70) 4-F-4′-NO₂ (3.34); 4-Cl-4′-NO₂ (3.17); 4-Br-4′-NO₂ (4.23); 4-I-4′-NO₂ (3.34); 4-CN-4′-NO₂ (2.71); 4-CN (4.23D.); and for Ph₂S: 4-CH₃-4′-NO₂ (4.67); 4-F-4′-NO₂ (3.54); 4-Cl-4′-NO₂ (3.40); 4-Br-4′-NO₂ (3.42); 4-I-4′-NO₂ (3.52); 4-CN-4′-NO₂ (3.36); 4-CN (4.14). Overall tendencies in the 2 series were similar. Halogen derivatives in both series had similar dipole moments. 30 references. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Reference of 21969-05-1).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Reference of 21969-05-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Compounds of the type C₆H₅-X-C₆H₅. II. Group and bond moments in 4-Y,4′-NO₂ derivatives of diphenyl ether and diphenyl sulfide was written by Rolla, Mario;Sanesi, Manlio. And the article was included in Ricerca Scientifica, Parte 2: Rendiconti, Sezione A: Abiologica in 1961.Electric Literature of C12H8INO3 The following contents are mentioned in the article:

cf. ibid. 43. A semiquant. method is proposed for the evaluation of group and bond moments of p-YC₆H₄OC₆H₄NO₂-p (I) and p-YC₆H₄SC₆H₄NO₂-p (II) (where Y = Me, F, Cl, Br, I, CN, and NO₂) from known dipole moments and bond angles. In these compounds the degree of conjugation of the NO₂ group is higher than in PhNO₂, but slightly lower than in p-O₂NC₆H₄OPh and p-O₂NC₆H₄SPh; halogen conjugation is lower than in the corresponding C₆H₆ derivatives, but higher than in p-YC₆H₄OPh and p-YC₆H₄SPh. I and II (Y = CN or NO₂) show much lower apparent conjugation than expected. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Electric Literature of C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Electric Literature of C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Palladium supported on zinc ferrite: an efficient catalyst for ligand free C-C and C-O cross coupling reactions was written by Singh, Abhilash S.;Shendage, Suresh S.;Nagarkar, Jayashree M.. And the article was included in Tetrahedron Letters in 2013.COA of Formula: C12H8INO3 The following contents are mentioned in the article:

An efficient superparamagnetic Pd-ZnFe₂O₄ solid catalyst has been synthesized by loading Pd(0) species on zinc ferrite nanoparticles. Sonogashira cross couplings between terminal alkynes and aryl halides were achieved in the absence of any Cu co-catalyst. A Heck-Matsuda coupling reaction of structurally different aryldiazonium tetrafluoroborate substrates was preceded at 40 °C in water. Cyanation of aryl halides was successfully done using K₄[Fe(CN)₆] as the cyanide source over Pd-ZnFe₂O₄. The catalyst was also employed for Ullmann type cross coupling reactions. Excellent yield of the products, reusability, and uncomplicated work-up make this catalyst efficient for C-C and C-O coupling reactions. Good yield of products, easy separation, and negligible leaching of Pd from the catalyst surface confirm the true heterogeneity in these catalytic reactions. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1COA of Formula: C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.COA of Formula: C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis and characterization of new polyimides derived from 4,4′-bis(p-aminophenoxy)triphenylamine and N,N-bis[4-(4′-aminophenoxy)phenyl]aminopyrene was written by Kurosawa, Tadanori;You, Nam-Ho;Higashihara, Tomoya;Ueda, Mitsuru. And the article was included in PMSE Preprints in 2009.Electric Literature of C12H8INO3 The following contents are mentioned in the article:

The synthesis and properties of new polyimides (PIs) derived from 4,4′-bis(p-aminophenoxy)triphenylamine (APT) and N,N-bis[4-(4′-aminophenoxy)phenyl]aminopyrene (APPA) for memory device application is reported. The starting monomers were prepared from 4-iodophenol and 4-fluoronitrobenzene via etherification (giving 4-(4′-nitrophenoxy)iodobenzene) followed by amination with aniline or aminopyrene and final reduction of terminal nitro-group. Polyimides were synthesized by polycondensation of each monomer with hexafluoroisopropylidene-2,2-bis(phthalic anhydride) in dimethylacetamide. All PIs had electron-rich arylamine moieties combining flexible phenyl-ether linkages which provide polymers electron-donating properties to reduce driving voltage in a memory device. The PIs exhibited high thermal properties such as 10% weight loss temperature >500° and glass transition temperatures >250°. The effects of structure on the thermal, optical, and electrochem. properties of the PIs are described in detail. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Electric Literature of C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Electric Literature of C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Oxidations with phenyliodoso acetate. VI. Oxidation of phenols containing electron-attracting substituents was written by Fox, A. R.;Pausacker, K. H.. And the article was included in Journal of the Chemical Society in 1957.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:

Some p-alkoxycarbonyl- or p-nitrophenols were oxidized with PhI(OAc)₂ (I) in C₆H₆ solution; 4-alkoxycarbonyl- or 4-nitro-2-iododiphenyl ethers were formed. In AcOH p-O₂NC₆H₄OH (II) gave a compound believed to be 2-hydroxy-5-nitrodiphenyliodonium acetate (III). III could readily be rearranged to 2-iodo-4-nitrodiphenyl ether (IV). II (5.4 g.) and 9.7 g. I in 300 ml. dry thiophene-free C₆H₆ set aside 48 hrs. at room temperature gave 2 g. brown amorphous precipitate; the filtrate chromatographed on silica gave 0.8 g. of a first band (compound A), needles, m. 61° (from MeOH), m.p. undepressed with authentic IV. The 2nd band yielded 0.6 g. compound B, yellow plates, m. 120° (from alc.); monoacetyl derivative, brown prisms, m. 126°; monomethyl ether, needles, m. 128° (from alc.). When only compound A was required, Al₂O₃ was used as an adsorbent, since compound B was strongly absorbed. With m-chlorophenyliodoso acetate (V) as oxidizing agent the products were (a) 2 g. C₆H₆-insoluble material, (b) 1 g. 3′(?)-chloro-2-iodo-4-nitrodiphenyl ether, needles, m. 64° (from MeOH), and 0.4 g. compound B. H₂O₂ (12 ml., 38%) and 53 ml. Ac₂O stirred 4 hrs. at 40° and 10 g. m-ClC₆H₄I added gave 15 g. V, m. 154°. 2-Chloro-5-nitroacetanilide (3.5 g.) and 0.1 g. Cu added to a mixture of 5.3 g. PhOH and 3.6 g. KOH which had previously been heated to 140°, after 0.5 hr. heating at 150-60° the mixture poured into a solution of 5 g. NaOH in 50 ml. ice H₂O, and the product isolated gave 2.5 g. 2-acetamido-4-nitrodiphenyl ether (VI), needles, m. 123°. Refluxing 2.2 g. VI with 20 ml. 20% HCl and basifying gave 2-amino-4-nitrodiphenyl ether (VII), m. 106°. VII diazotized and treated with KI gave 60% IV, identical with compound A. Compound A (0.58 g.) hydrogenated with 5 ml. Raney Ni and 0.3 g. KOH in 25 ml. alc. gave 20% 4-aminodiphenyl ether, m. 81°. o-IC₆H₄OH (1.8 g.) heated 0.5 hr. at 160° with p-FC₆H₄NO₂ and 0.5 g. KOH gave 2-iodo-4′-nitrodiphenyl ether, m. 104°. Similarly prepared were 3-iodo-4′-nitrodiphenyl ether, yellow needles, m. 84° (from MeOH), and 4-iodo-4′-nitrodiphenyl ether, m. 64°. The latter liquefied on mixing. with compound A. Compound B (1.15 g.) hydrogenated in alc. with 5 g. Raney Ni and the crude amine (0.88 g.) diazotized in concentrated HCl, treated 48 hrs. at 2° with a 20-molar excess of 50% hypophosphorous acid, the mixture extracted with Et₂O, and washed, gave m-methoxydiphenyl ether, b₃ 145°, which could not be crystallized o-Methoxydiphenyl ether m. 77°. m-MeOC₆H₄OH and p-ClC₆H₄NO₂ gave 3-methoxy-4′-nitrodiphenyl ether, plates, m. 88° (from alc.). 3,4-Dinitrophenol (VIIa) (4.6 g.), 8.1 g. I, and 400 mg. C₆H₆ refluxed 9.25 hrs. and the solution chromatographed on Al₂O₃ gave 0.71 g. 2(?)-iodo-4,5-dinitrodiphenyl ether (VIIb), yellow crystals, m. 115° (from cyclohexane). The oxidation of 3.8 g. Me p-hydroxybenzoate with 1 and 2 moles I in C₆H₆ at room temperature gave 1.9 g. and 3.1 g., resp., 2(?)-iodo-4-methoxycarbonyldiphenyl ether (VIII), m. 63° (from MeOH). Similarly, the oxidation of Et p-hydroxybenzoate (4.2 g.) gave 1.6 g. and 3.1 g., resp. of 4-ethoxy-2(?)-iododiphenyl ether (IX), b_1.3 215°. When IX or VIII was hydrolyzed with aqueous alc. NaOH, 70% 4-carboxy-2(?)-iododiphenyl ether (X) was obtained as needles, m. 160° (from MeOH). 2,6-Dichloro-4-nitrophenol (8.8 g.) and 16.1 g. I in 1 l. C₆H₆ kept 50 days at 45° and the solution chromatographed on Al₂O₃, gave a red band of 3.55 g. 2,6-dichloro-1,4-benzoquinone, orange needles, m. 123° (from ligroine). II (4.4 g.) and 12 g. I in 50 ml. AcOH set aside 36 hrs. gave 10 g. crude product; the residue refluxed 2 hrs. in C₆H₆, and chromatographed on Al₂O₃ yielded 0.6 g. compound A. The combined precipitates (compound C) washed with Et₂O, m. 156°. When compound C was heated several hrs. at 164° it gave 95% compound A. Similarly, when 0.55 g. compound C refluxed 2 hrs. with alc., AcOH, or C₆H₆ was converted to compound A in yields of 83, 87, and 92%, resp. Compound C (1.8 g.) refluxed 2 hrs. with 50 ml. 2N NaOH gave 0.5 g. compound A and 0.7 g. intractable brown tar. Compound C (5 g.) refluxed 0.5 hr. with 60 ml. 10% HCl gave 4.7 g. product, m. 210°. Compound C suspended in dioxane and left 10 days with excess Et₂O and CH₂N₂ gave 88% compound A. 3-Methoxy-4-nitrophenol (0.56 g.) oxidized with 1.12 g. I in 50 ml. AcOH gave 0.93 g. 2(?)-iodo-5-methoxy-4-nitrodiphenyl ether, needles, m. 103° (from MeOH). p-Ethoxycarbonylphenol (1 g.) similarly oxidized 13 hrs. gave 4-ethoxycarbonyl-2(?)-iododiphenyl ether, which on hydrolysis gave X. VIIa (2 g.), 3.64 g. I, and 50 ml. AcOH heated 5 hrs. at 78° gave 3.41 g. VIIb. Solutions of 1.3 g. II and 2.4 g. I in C₆H₆ saturated with 100 ml. and 150 ml. C₆H₆, resp., set aside 15 hrs. and the product chromatographed gave 0.4 g. compound A. Finely powdered I (40 g.) stirred 0.5 hr. in 100 g. BzOH and 800 ml. Et₂O until solution was effected, the solution stirred a further 2 hrs., and the solids collected gave 51 g. PhI(OBz)₂, m. 161°. The mechanisms of the above reactions were discussed. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Quality Control of 1-Iodo-4-(4-nitrophenoxy)benzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Decomposition of the salts of p-X-benzenediazonium complexes by 18-crown-6 in p-iodoanisole was written by Eustathopoulos, Helene;Court, Jean;Lambeaux, Claude;Bonnier, Jane Marie. And the article was included in Nouveau Journal de Chimie in 1985.Safety of 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:

The decomposition of para-substituted benzenediazonium ions complexed with 18-crown-6 has been studied. Anal. of the reaction products from the thermal decomposition of the complexed diazonium salts in p-iodoanisole solution showed that the nature of the para substituent drastically changed the reaction mechanism. The decomposition of the complex p-nitrobenzenediazonium ion proceeds through a radical pathway. In addition to isomeric (p-nitrophenyl)iodoanisoles, the decomposition affords 2,4′-dimethoxy-5-iodobiphenyl and 5,4′-dimethoxy-2-iodobiphenyl, which result from the attack of p-iodoanisole by p-anisidyl radicals derived from the 4-methoxy-4′-nitrophenyliodinyl radical. 4-Iodo-4′-nitrodiphenyl ether and 4-methoxy-4′-nitrobiphenyl could not be detected; therefore, with a strong electron-withdrawing substituent, the decomposition mechanism is exclusively homolytic. The thermal decomposition of the complexed p-chlorobenzenediazonium salt affords products derived from the reaction of the p-chlorophenyl cation and products derived from the reaction of the p-chlorophenyl radical. At [crown ether]/[p-ClC₆H₄N₂⁺] = 6, the homolysis represents at least 30% of the total decomposition This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Safety of 1-Iodo-4-(4-nitrophenoxy)benzene).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Safety of 1-Iodo-4-(4-nitrophenoxy)benzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Substitution products of 4-nitro- and 4-acetamidodiphenyl ether was written by Scarborough, Harold A.. And the article was included in Journal of the Chemical Society in 1929.Name: 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:

4-ClC₆H₄OC₆H₄NO₂-4 (I), m. 76°, results from 4-O₂NC₆H₄OPh (II) and Cl in AcOH or from p-O₂NC₆H₄Cl and p-ClC₆H₄OK; the 4-Br derivative (III), m. 61°, was prepd, similarly. 4-NO₂CdH₄OPh and ICl in AcOH give 4-iodo-4′-nitrodiphenyl ether (IV), pale yellow, m. 71°; Cl precipitates a stable iodochloride, yellow. II or III in dry Br or p-ClC₆H₄NO₂ and 2,4-Br₂C₆H₃OK give 2,4-dibromo-4′-nitrodiphenyl ether, m. 81°. Reduction of II in EtOH- or Et₂O-HCl with SnCl₂ gives 4-aminodiphenyl ether-HCl, m. 238°; the Ac derivative, m. 127°. Reduction of I gives the NH₂ derivative, m. 101°, whose Ac derivative (V), m. 146°. Nitration of V gives the 3-NO₂ derivative, yellow, m. 98°; hydrolysis gives 4′-chloro-3-nitro-4-aminodiphenyl ether, m. 114°; deamination gives 4′-chloro-3-nitrodiphenyl ether, yellow, m. 60°. 4-Bromo-4′-acetaminodiphenyl ether, m. 161°; nitration gives 4′-bromo-3-nitro-4-acetaminodiphenyl ether, yellow, m. 107°; hydrolysis gives the free NH₂ derivative, scarlet, m. 144°; deamination gives 4′-bromo-3-nitrodiphenyl ether, yellow, m. 64°. 4-Iodo-4′-aminodiphenyl ether, m. 91°; Ac deriv; m. 174°. 4′-Iodo-3-nitro-4-acetaminodiphenyl ether, yellow, m. 123°; hydrolysis gives the free NH₂ derivative, scarlet, m. 155°. 3-Nitro-4-aminodiphenyl ether, bright red, m. 82°; Ac derivative, deep yellow, m. 100°. 2,4-Dibromo-4′-acetaminodiphenyl ether, m. 158°; 3′-NO₂ derivative, yellow, m. 141°; the free NH₂ derivative, yellow, m. 107°; deamination gives 2,4-dibromo-3′-nitrodiphenyl ether, orange, m. 72°. 4-Iododiphenyl ether, m. 48°; dichloride, yellow. 4-Bromo-4′-iododiphenyl ether, m. 72°. 4,4′-Diiododiphenyl ether, m. 139°. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Name: 1-Iodo-4-(4-nitrophenoxy)benzene).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.Name: 1-Iodo-4-(4-nitrophenoxy)benzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

High performance volatile polymeric memory devices based on novel triphenylamine-based polyimides containing mono- or dual-mediated phenoxy linkages was written by Kuorosawa, Tadanori;Chueh, Chu-Chen;Liu, Cheng-Liang;Higashihara, Tomoya;Ueda, Mitsuru;Chen, Wen-Chang. And the article was included in Macromolecules (Washington, DC, United States) in 2010.Recommanded Product: 1-Iodo-4-(4-nitrophenoxy)benzene The following contents are mentioned in the article:

Two novel functional polyimides (PIs), PI(AAPT-TPA) and PI(APT-TPA), consisting of electron-donating 4-amino-4′-(p-aminophenoxy)-triphenylamine (AAPT) or 4,4′-bis(p-aminophenoxy)-triphenylamine (APT) and electron-accepting phthalimide moieties, were prepared for the memory device applications. The TPA moieties as electron donor are expected to enhance the electron donating and charge transport ability with phthalimide moieties (electron acceptor). The monophenoxy linkage PI(AAPT-TPA) had a higher T_g and a lower band gap than the dual-phenoxy linkage PI(APT-TPA). It suggested the more rigid backbone of the former and led to different memory characteristics. The memory devices with the configuration of ITO/PI/Al exhibited two conductivity states and could be swept pos. or neg. with a high ON/OFF current ratio of 10⁸-10⁹. The PI(AAPT-6FDA) device relaxed from the ON state to the OFF state quickly after the applied voltages was removed, whereas the ON state of the PI(APT-6FDA) device could remain for around 4 min after the power was turned off. Probably dynamic random access memory (DRAM) was exhibited for the PI(AAPT-6FDA) device and static random access memory (SRAM) was for the PI(APT-6FDA) device. The volatile memory characteristics were probably attributed to the unstable charge transfer (CT) complex based on the weak theor. dipole moments of the studied PIs. The dual-mediated phenoxy linkage of PI(APT-6FDA) led to the more twisted conformation compared to the monosubstituted PI(AAPT-6FDA) based on the theor. anal. by the d. functional theory (DFT) method. It thus produced a potential barrier for delaying the back CT process by the elec. field and explained the SRAM characteristic. The present study suggested the importance of the TPA structure for the memory characteristics. The fast switching and high ON/OFF characteristics also indicated the new TPA based polyimides for advanced memory technol. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Recommanded Product: 1-Iodo-4-(4-nitrophenoxy)benzene).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Recommanded Product: 1-Iodo-4-(4-nitrophenoxy)benzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodo derivatives of diphenyl ether. I. The mono- and certain diiodo derivatives of diphenyl ether and of 2- and 4-carboxydiphenyl ethers was written by Brewster, R. Q.;Strain, Franklin. And the article was included in Journal of the American Chemical Society in 1934.Electric Literature of C12H8INO3 The following contents are mentioned in the article:

Most of the following compounds were prepared by standard methods. 2-IC₆H₄OPh, m. 56°; 3-I isomer, b₃ 155°, b₂₀ 194-6°, d²⁵ 1.616, n²⁵ 1.643; 4-I isomer, m. 47°; 2-iodo-4′-nitro derivative, m. 104°; 4-I isomer, m. 70°; 2-iodo-4′-amino derivative, m. 69° (Ac derivative, m. 150°); 2-IC₆H₄OC₆H₄I-4, m. 48°; 2-nitro-4′-iododiphenyl ether, m. 86° (constitution proved for 1st time); 3,4′-dinitrodiphenyl ether, m. 123°; 3,4′-diamino derivative, m. 72° (di-Ac derivative, m. 192°); 3,4′-diiododiphenyl ether, b₃ 200°, d²⁵ 2.051, n²⁵ 1.696; 4-phenoxyphenylurethane, m. 63°; 4-iodophenoxy derivative, m. 126°; 4-(4-iodophenoxy)-phenylurea, m. 201°; (4-IC₆H₄)₂O, m. 139°; 2-amino-4-nitrodiphenyl ether, m. 107°; 2-I derivative, m. 61°; 2-iodo-4-amino derivative, b₃ 203°, d²⁵ 1.667, n²⁵ 1.677 (Ac derivative, m. 120°); 2,4-diiododiphenyl ether, b₃ 198°, d²⁵ 2.056, n²⁵ 1.700; 3-nitro-4-aminodiphenyl ether, m. 82°; 3,4-diamino derivative, m. 69° (di-Ac derivative, m. 188°); 3-nitro-4-iodo derivative, b₃ 195°, d²⁵ 1.722, n²⁵ 1.657; 3-amino derivative, b₃ 188°, d²⁵ 1.664, n²⁵ 1.676 (Ac derivative, m. 144°); 3,4-di-I derivative, b₃ 208°, d²⁵ 2.055, n_D²⁵ 1.700; o-ClC₆H₄CO₂H, PhOH, NaOH and a little Cu, heated at 190° for 15 min. give 2-PhOC₆H₄CO₂H; p-ClC₆H₄NO₂ and o-KOC₆H₄CHO, heated 6 h. at 190-200°, give 2-(4-nitrophenoxy)benzaldehyde, m. 112°; oxidation of the aldehyde or nitration of 2-PhOC₆H₄CO₂H gives the corresponding acid, m. 157°; 4-amino derivative, m. 180° (Ac derivative, m. 185°); 4-I derivative, m. 143°; heating the latter with concentrated H₂SO₄ at 100° for 10 min. gives 2-iodoxanthone, m. 156°. 2-Phenoxy-5-aminobenzoic acid, m. 164° (Ac derivative, m. 165°); 5-I derivative, m. 148°. 2-(2-Nitrophenoxy)benzaldehyde, m. 77°; the acid m. 153°; 4-nitroxanthone, m. 190°; 2-(2-aminophenoxy)benzoic acid, m. 153° (Ac derivative, m. 179°); the lactam m. 211°. 2-(2-Iodophenoxy)benzoic acid, m. 133°; the 4-(4-iodophenoxy) derivative m. 217°; 2-(4-iodophenoxy)-5-nitrobenzoic acid, m. 178°; the 5-amino derivative m. 185°; 2-(4-nitrophenoxy)-5-nitrobenzoic acid, the α-form m. 158° and the β-form. m. 170-1°; the α-form is converted into the β-form above its m. p.; 2-(4-iodophenoxy)-5-iodobenzoic acid, m. 176°. These compounds, with the possible exception of the iodocarboxy compounds, do not possess any marked physiol. activity. This study involved multiple reactions and reactants, such as 1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1Electric Literature of C12H8INO3).

1-Iodo-4-(4-nitrophenoxy)benzene (cas: 21969-05-1) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Electric Literature of C12H8INO3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com