Category: 21784-73-6

Li, Wen-Pei published the artcileAcid-Free Copper-Catalyzed Electrophilic Nitration of Electron-Rich Arenes with Guanidine Nitrate, SDS of cas: 21784-73-6, the main research area is arene guanidine nitrate copper catalyst electrophilic nitration; nitroarene preparation.

A practical copper-catalyzed nitration of electron-rich arenes with trimethylsilyl chloride and guanidine nitrate is reported. A variety of nitrated products were generated in moderate to excellent yields (32%-99%) at ambient temperature under acid free, open-flask and operationally simple conditions.

Journal of Organic Chemistry published new progress about Nitration. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, SDS of cas: 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bartos, Paulina published the artcileSubstituent effects on the electronic structure of the flat Blatter radical: correlation analysis of experimental and computational data, Application of 4-Iodo-2-nitrophenol, the main research area is phenyl triazinophenoxazinyl preparation crystal structure substituent effect.

A series of C(10)-substituted derivatives of 2-Ph-3H-[1,2,4]triazino[5,6,1-kl]phenoxazin-3-yl was obtained using the aza-Pschorr, photochem. and radical-induced cyclization reactions, and through functional group transformations of the C(10)-amino and C(10)-iodo derivatives The iodo derivative underwent Pd-catalyzed C-C cross coupling reactions leading to the installation of Ph, 2-thienyl and ethynylbenzene groups at the C(10) position effectively extending electronic conjugation. The substituent effect on the electronic properties of the 3H-[1,2,4]triazino[5,6,1-kl]phenoxazin-3-yl was investigated in twenty one derivatives with a diverse range of functional groups by spectroscopic (UV-vis and EPR) and electrochem. methods augmented with DFT calculations Results show that the lowest energy electronic absorption and redox potentials correlate well with the σp substituent parameter, while aN hfcc and the N-H bond dissociation energy (BDE) are well described by the σm parameter. In general, increasing the electron donating ability of the C(10)-X substituent lowers the π-π*(1) excitation energy, cathodically shifts the redox potentials, increases spin delocalization beyond the [1,2,4]triazinyl ring and lowers BDE. The latter two parameters are important indicators of the overall radical stability. Mol. and crystal structures of three radicals were established with the single crystal XRD method.

New Journal of Chemistry published new progress about Acylation. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Application of 4-Iodo-2-nitrophenol.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gershon, H. published the artcileAntifungal activity of halophenols and halonitrophenols/, Computed Properties of 21784-73-6, the main research area is fungicide halophenol halonitrophenol.

Thirty one compounds (phenol, 12 monohalo derivatives and 18 nitrophenols, i.e. 2- and 4-nitrophenols, 4-, 5- and 6-halo-2-nitrophenols, 3-halo-4-nitrophenols) were tested for antifungal activity against six fungi (Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth. The two most fungitoxic compounds were 5-fluoro- and 5-iodo-2-nitrophenol, which inhibited all the fungi at <10 μg/mL. 6-Iodo-2-nitrophenol inhibited 5 fungi at <10 μg/mL and M. cirinelloides at 10-100 μg/mL. Monatshefte fuer Chemie published new progress about Fungicides. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Computed Properties of 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pinto, M. F. S. published the artcilePattern recognition study of structure-activity relationship of halophenols and halonitrophenols against fungus T. mentagrophytes, Recommanded Product: 4-Iodo-2-nitrophenol, the main research area is halophenol halonitrophenol structure activity relationship fungicide Trichophyton; pattern recognition structure activity relationship antifungal halophenol halonitrophenol.

Compounds (halophenols and halonitrophenols) with antifungal activity against the fungus species Trichophyton mentagrophytes are proposed with the aid of techniques of structure-activity relationship. Mol. parameters were calculated with quantum chem., structure-activity relationship and quant. structure-activity relationship programs. Principal components anal., hierarchical cluster anal. and stepwise discriminant anal. methods showed that the parameters polarizability (Pol), heat of formation (ΔHf), lowest unoccupied orbital energy (εLUMO), dipole moment (μ), hydration energy (HE) and surface area (A) are responsible for the separation between the active and inactive compounds

Journal of Molecular Structure: THEOCHEM published new progress about Fungicides. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Recommanded Product: 4-Iodo-2-nitrophenol.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Padin, Damian published the artcileRuthenium-Catalyzed Tandem Carbene/Alkyne Metathesis/N-H Insertion: Synthesis of Benzofused Six-Membered Azaheterocycles, COA of Formula: C6H4INO3, the main research area is benzofused six membered azaheterocycle preparation; alkynylaniline trimethylsilyldiazomethane ruthenium catalyst.

The Cp*RuCl-based catalyst enables expedient access to a variety of benzofused six-membered azaheterocycles from unprotected o-alkynylanilines and trimethylsilyldiazomethane through an unprecedent tandem carbene/alkyne metathesis/N-H insertion reaction. The transformation takes place under mild reaction conditions (room temperature, <15 min) and with excellent functional group tolerance. The synthetic utility of the final products and a mechanistic rationale are also discussed. Organic Letters published new progress about Alkylation. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, COA of Formula: C6H4INO3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Oshikawa, Yuji published the artcileCell Surface-Anchored Fluorescent Probe Capable of Real-Time Imaging of Single Mast Cell Degranulation Based on Histamine-Induced Coordination Displacement, COA of Formula: C6H4INO3, the main research area is cell surface fluorescence probe imaging mast degranulation histamine coordination.

Mast cells secrete histamine upon degranulation triggered by various stimuli. Herein, we report the new detection method of mast cell degranulation using the fluorescent probe capable of detection of the released histamine. The probe was designed as the Co(II) complex of a cyanine dye, which shows a turn-on fluorescence signal based on a histamine-induced coordination displacement mechanism. Fluorescence imaging using the cell surface-anchored fluorescent probe enabled the real-time detection of mast cell degranulation induced by various secretagogues.

Analytical Chemistry (Washington, DC, United States) published new progress about Fluorescence. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, COA of Formula: C6H4INO3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bekarek, V. published the artcileCorrelations between proton chemical shifts of hydroxyl groups with intramolecular hydrogen bondings and Hammett substituent constants, Quality Control of 21784-73-6, the main research area is hydrogen bonding intramol; proton chem shift; chem shift proton; shift chem proton; intramol H bonding; hydroxyl group chem shift; Hammett substituent constant.

The dependence of the proton chem. shifts of OH groups on Hammett σ constant is proposed in the form: τ = a + bσ1 + cσ2. bσ1 describes the substituent effect on the proton chem. shift of the OH group across the O-H bond and cσ2 the effect of substituents upon the electron donor involved in the formation of the H bonding. Three series of compounds were used to test the validity of the equation proposed, namely, 0-nitrophenols, salicylaldehydes, and 0-hydroxyazobenzenes. The values of the constant a, b, and c were calculated by the least sqs. method: 0-nitrophenols: -0.57, -1.260, +0.990; salicylaldehydes: -0.93, -1.186, +0.900; and 0-hydroxyazobenzenes: -1.21, -2.040, +2.484. A good agreement was found for substituted 0-nitrophenols. In the case of salicylaldehydes a considerable deviation was found for the 5-NO2 derivative There is an intramol. H bonding under exptl. conditions and such H bonding exists even in 0-hydroxyazobenzene for the data measured in Me2SO.

Collection of Czechoslovak Chemical Communications published new progress about Hydrogen bond. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Quality Control of 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ansari, Nurul N. published the artcileChemoselectivity in the Kosugi-Migita-Stille coupling of bromophenyl triflates and bromo-nitrophenyl triflates with (ethenyl)tributyltin, Quality Control of 21784-73-6, the main research area is bromophenyl triflate bromonitrophenyl triflate ethenyl tributyltin Stille coupling chemoselective.

Kosugi-Migita-Stille cross coupling reactions of (ethenyl)tributyltin with all isomeric permutations of bromophenyl triflate and bromo-nitrophenyl triflate were examined in order to determine the chemoselectivity of carbon-bromine vs. carbon-triflate bond coupling under different reaction conditions. In general, highly selective carbon-bromine bond cross couplings were observed for example bis(triphenylphosphine)palladium dichloride (2 mol %) in 1,4-dioxane at reflux. In contrast, reactions using the same pre-catalyst but in the presence of a three-fold excess of lithium chloride in N,N-dimethylformamide at ambient temperature were in most cases selective for coupling at the carbon-triflate bond. Overall, isolated yields and the selectivity for carbon-bromine bond coupling were significantly higher compared to carbon-triflate bond coupling.

Tetrahedron published new progress about Chemoselectivity. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Quality Control of 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pan, Wen-Bin published the artcileNitrophenol derivatives obtained by oxidation with cerium(IV) ammonium nitrate (CAN) and their cytotoxicity, Safety of 4-Iodo-2-nitrophenol, the main research area is phenol derivative nitration cerium ammonium nitrate; nitrophenol derivative preparation antitumor; cerium ammonium nitrate nitration mediator.

Nitration of a series of phenols with cerium(IV) ammonium nitrate in acetonitrile under mild conditions yielded the mixture of corresponding nitrophenols. The prepared compounds have been tested for their antitumor activity on Hep G2, Hep 3B, MCF-7 and MDA-MB-231 cancer cell lines. Some of them showed selective activities.

Journal of the Chinese Chemical Society (Taipei, Taiwan) published new progress about Antitumor agents. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Safety of 4-Iodo-2-nitrophenol.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wei, Wen-Ting published the artcileRoom-Temperature, Water-Promoted, Radical-Coupling Reactions of Phenols with tert-Butyl Nitrite, Related Products of iodides-buliding-blocks, the main research area is room temperature radical cross coupling phenol tert butyl nitrite; ortho nitrated phenol preparation carbon water promoted cross coupling.

A radical-radical cross-coupling reaction of phenols with tert-Bu nitrite has been developed with the use of water as an additive. This method allows the construction of C-N bonds under an air atm. at room temperature, providing the ortho-nitrated phenol derivative in moderate to good yields.

Synlett published new progress about C-N bond formation. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Related Products of iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com