Synthesis, characterization and antibacterial activity of some halo substituted Schiff bases was written by Junne, S. B.;Kadam, Archana B.;Shinde, S. L.;Waghamare, G. S.;Vibhute, Y. B.. And the article was included in E-Journal of Chemistry in 2010.Recommanded Product: 2-Amino-4-iodobenzoic acid This article mentions the following:
Halo substituted Schiff bases were designed and the synthesis of the target compounds was achieved using aryl amines and aryl aldehydes as starting materials and the products thus obtained were confirmed by IR and NMR. Example compounds thus prepared included 4-amino-2-nitro-N-[(3,4,5-trimethoxyphenyl)methylene]benzenamine, 2-bromo-4-[[(5-bromo-2-pyridinyl)imino]methyl]-6-methoxyphenol, etc. These compounds were screened against pathogenic bacteria by an agar diffusion method (Dermatophilus congolensis, Gram-pos., Mud fever, Staphylococcus aureus, Corynebacterium parvum, acne, Actinomyces bovis). In the experiment, the researchers used many compounds, for example, 2-Amino-4-iodobenzoic acid (cas: 20776-54-9Recommanded Product: 2-Amino-4-iodobenzoic acid).
2-Amino-4-iodobenzoic acid (cas: 20776-54-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C閳ユ彂 bond is the weakest of the carbon閳ユ従alogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Recommanded Product: 2-Amino-4-iodobenzoic acid
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com