Category: 207115-22-8

Low-Temperature Cross-Linking Benzocyclobutene Based Polymer Dielectric for Organic Thin Film Transistors on Plastic Substrates was written by Hallani, Rawad K.;Moser, Maximilian;Bristow, Helen;Jenart, Maud V. C.;Faber, Hendrik;Neophytou, Marios;Yarali, Emre;Paterson, Alexandra F.;Anthopoulos, Thomas D.;McCulloch, Iain. And the article was included in Journal of Organic Chemistry in 2020.Electric Literature of C6H4BrIO This article mentions the following:

The synthesis of a new benzocyclobutene based polymer, PSBBB, designed as a dielec. material for use in organic thin film transistors was reported. Compared to conventional benzocyclobutene-based materials, the introduction of a butoxide substituent at the 7-position of the benzocyclobutene pendant unit on the polymer allowed PSBBB to be cross-linked at temperatures of 120°, thus rendering it compatible with the processing requirements of flexible plastic substrates. The crosslinking behavior of PSBBB was studied by FTIR spectroscopy and DSC, demonstrating crosslinking of the polymer after curing at 120°. Bottom-gate bottom-contact organic thin film transistors were fabricated using PSBBB as dielec., affording a performance comparable to that of other dielec. polymeric materials. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Electric Literature of C6H4BrIO).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Electric Literature of C6H4BrIO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodothyronine Deiodinase Mimics. Deiodination of o,o’-Diiodophenols by Selenium and Tellurium Reagents was written by Vasil’ev, Andrei A.;Engman, Lars. And the article was included in Journal of Organic Chemistry in 1998.SDS of cas: 207115-22-8 This article mentions the following:

To better understand, and in the extension mimic, the action of the three selenium-containing iodothyronine deiodinases, o,o’-diiodophenols were reacted under acidic conditions with sodium hydrogen telluride, benzenetellurol, sodium hydrogen selenide, or benzeneselenol and under basic conditions with the corresponding deprotonated reagents. Sodium hydrogen telluride was found to selectively remove one iodine from a variety of 4-substituted o,o’-diiodophenols, including a protected form of thyroxine. Thus, it mimics the D1 variety of the iodothyronine deiodinases. Sodium telluride was a more reactive deiodinating agent toward o,o’-diiodophenols, often causing removal of both halogens. Benzenetellurol and sodium benzenetellurolate sometimes showed useful selectivity for monodeiodination. However, the products were often contaminated by small amounts of organotellurium compounds Sodium hydrogen selenide, sodium selenide, benzeneselenol, and sodium benzeneselenolate were essentially unreactive toward o,o’-diiodophenols. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8SDS of cas: 207115-22-8).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.SDS of cas: 207115-22-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A General Approach to Optically Pure [5]-, [6]-, and [7]Heterohelicenes was written by Zadny, Jaroslav;Jancarik, Andrej;Andronova, Angelina;Samal, Michal;Vacek Chocholousova, Jana;Vacek, Jaroslav;Pohl, Radek;Saman, David;Cisarova, Ivana;Stara, Irena G.;Stary, Ivo. And the article was included in Angewandte Chemie, International Edition in 2012.COA of Formula: C6H4BrIO This article mentions the following:

A general method for the preparation of optically pure [5]-, [6]-, and [7]heterohelicenes is based on a Co^I– or Ni⁰-catalyzed diastereoselective [2+2+2] cycloisomerization of centrally chiral triynes to deliver helicenes containing two 2H-pyran rings. The configuration, which can be predicted, does not depend on helicene length or functional groups present. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8COA of Formula: C6H4BrIO).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.COA of Formula: C6H4BrIO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation was written by Ni, Hui-Qi;Kevlishvili, Ilia;Bedekar, Pranali G.;Barber, Joyann S.;Yang, Shouliang;Tran-Dube, Michelle;Romine, Andrew M.;Lu, Hou-Xiang;McAlpine, Indrawan J.;Liu, Peng;Engle, Keary M.. And the article was included in Nature Communications in 2020.Product Details of 207115-22-8 This article mentions the following:

A method that enables direct access to these core structures, e.g., I from non-conjugated alkenyl amides RNHC(O)CH(R²)CH=CHR¹ [R = quinolin-8-yl, pyridin-2-yl; R¹ = H, Me, Et; R² = H, CH₃, CH₂C₆H₅, 3-CH₃OC₆H₄(CH₂)₂, (CH₂)₂OCH₂C₆H₅, (CH₂)₂CH=CH₂] and N-3-buten-1-yl-2-pyridinecarboxamide and ortho-iodoanilines, e.g., 4-iodopyridin-3-amine/phenols II (R³ = Me, Br, t-Bu, etc.; R⁴ = H, Br; R⁵ = H, I; X = O) has been described. Under palladium(II) catalysis this [3 + 2] heteroannulation proceeds in an anti-selective fashion and tolerates a wide variety of functional groups. N-Acetyl, -tosyl, and -alkyl substituted ortho-iodoanilines, as well as free -NH₂ variants, are all effective. Preliminary results with carbon-based coupling partners like Et 2-cyano-2-(2-iodophenyl)acetate, di-Me 2-(2-iodophenyl)malonate and Et 2-(benzenesulfonyl)-2-(2-iodophenyl)acetate also demonstrate the viability of forming indane core structures III (R⁶ = C(O)₂Me, C(O)₂Et; R⁷ = C(O)₂Me, CN, S(O)₂Ph) using this approach. Exptl. and computational studies on reactions with phenols support a mechanism involving turnover-limiting, endergonic directed oxypalladation, followed by intramol. oxidative addition and reductive elimination. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Product Details of 207115-22-8).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Product Details of 207115-22-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis of 2-Arylbenzo[b]furans via Copper(I)-Catalyzed Coupling of o-Iodophenols and Aryl Acetylenes was written by Bates, Craig G.;Saejueng, Pranorm;Murphy, Jaclyn M.;Venkataraman, D.. And the article was included in Organic Letters in 2002.Safety of 4-Bromo-2-iodophenol This article mentions the following:

We report a copper(I)-catalyzed procedure for the synthesis of 2-arylbenzo[b]furans. This protocol can be used to synthesize a variety of 2-arylbenzo[b]furans in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives, and is palladium-free. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Safety of 4-Bromo-2-iodophenol).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Safety of 4-Bromo-2-iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Symmetrically halogenated phenols was written by Brenans, P.;Yeu, K.. And the article was included in Compt. rend. in 1931.Recommanded Product: 4-Bromo-2-iodophenol This article mentions the following:

By the interaction of equimol. quantities of Br and 2-iodophenol in AcOH, an almost theoretical yield was obtained of 4-bromo-2-iodophenol (I), m. 71°; acetate, m. 60°; benzoate, m. 90°; Et ether, m. 34°. To confirm the position assigned to the Br atom, I was converted with I in alk. solution into 4,2,6-BrI₂C₆H₂OH, m. 128°; benzoate, m. 124° (C. A. 24, 5289). The addition of 2 mols. of Br to 2-iodophenol in AcOH forms 4,6-dibromo-2-iodophenol, m. 104°, previously prepared by the action of I and alkali on 3,5-dibromosalicylic acid. Equimol. quantities of 2,4-I₂C₆H₃OH and Cl in AcOH gave 6-chloro-2,4-diiodophenol (II), m. 96°; acetate, m. 90°; benzoate, m. 97°; Et ether, m. 68° (C. A. 7, 1706; 21, 3606). II may also be obtained by the use of SOCl₂ as a chlorinating agent. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Recommanded Product: 4-Bromo-2-iodophenol).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 4-Bromo-2-iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodination of aromatic compounds using potassium iodide and hydrogen peroxide was written by Reddy, K. Suresh Kumar;Narender, N.;Rohitha, C. N.;Kulkarni, S. J.. And the article was included in Synthetic Communications in 2008.Name: 4-Bromo-2-iodophenol This article mentions the following:

A simple, efficient, regioselective, and eco-friendly method for oxy-iodination of aromatic compounds is presented. In this method, the electrophilic substitutions of iodine generated in situ from KI as an iodine source and H₂O₂ as an O source were employed without any catalyst/mineral acid. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Name: 4-Bromo-2-iodophenol).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Name: 4-Bromo-2-iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Adamantyl-Substituted Retinoid-Derived Molecules That Interact with the Orphan Nuclear Receptor Small Heterodimer Partner: Effects of Replacing the 1-Adamantyl or Hydroxyl Group on Inhibition of Cancer Cell Growth, Induction of Cancer Cell Apoptosis, and Inhibition of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2 Activity was written by Dawson, Marcia I.;Xia, Zebin;Jiang, Tao;Ye, Mao;Fontana, Joseph A.;Farhana, Lulu;Patel, Bhaumik;Xue, Li Ping;Bhuiyan, Mohammad;Pellicciari, Roberto;Macchiarulo, Antonio;Nuti, Roberto;Zhang, Xiao-Kun;Han, Young-Hoon;Tautz, Lutz;Hobbs, Peter D.;Jong, Ling;Waleh, Nahid;Chao, Wan-ru;Feng, Gen-Sheng;Pang, Yuhong;Su, Ying. And the article was included in Journal of Medicinal Chemistry in 2008.Recommanded Product: 207115-22-8 This article mentions the following:

(E)-4-[3-(1-Adamantyl)-4′-hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC) induces the cell-cycle arrest and apoptosis of leukemia and cancer cells. Studies demonstrated that 3-Cl-AHPC bound to the atypical orphan nuclear receptor small heterodimer partner (SHP). Although missing a DNA-binding domain, SHP heterodimerizes with the ligand-binding domains of other nuclear receptors to repress their abilities to induce or inhibit gene expression. 3-Cl-AHPC analogs having the 1-adamantyl and phenolic hydroxyl pharmacophoric elements replaced with isosteric groups were designed, synthesized, and evaluated for their inhibition of proliferation and induction of human cancer cell apoptosis. Structure-anticancer activity relationship studies indicated the importance of both groups to apoptotic activity. Docking of 3-Cl-AHPC and its analogs to an SHP computational model that was based on the crystal structure of ultraspiracle complexed with 1-stearoyl-2-palmitoylglycero-3-phosphoethanolamine suggested why these 3-Cl-AHPC groups could influence SHP activity. Inhibitory activity against Src homol. 2 domain-containing protein tyrosine phosphatase 2 (Shp-2) was also assessed. The most active Shp-2 inhibitor was found to be the 3′-(3,3-dimethylbutynyl) analog of 3-Cl-AHPC. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Recommanded Product: 207115-22-8).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Recommanded Product: 207115-22-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Facile Benzo-Ring Construction via Palladium-Catalyzed Functionalization of Unactivated sp³ C-H Bonds under Mild Reaction Conditions was written by Feng, Yiqing;Wang, Yuji;Landgraf, Bradley;Liu, Shi;Chen, Gong. And the article was included in Organic Letters in 2010.Recommanded Product: 207115-22-8 This article mentions the following:

A practical synthetic method for the annulation of benzo-rings by the intramol. coupling of an aryl iodide and a methylene C-H bond is described. The palladium-catalyzed C-H functionalization is directed by an aminoquinoline carboxamide group, which can be easily installed (to form, e.g, I) and removed. High yields and broad substrate scope were achieved. An additive of ortho-Ph benzoic acid, identified from a systematic screening, functions as a critical ligand for the catalytic process under mild condition, even at near room temperature In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Recommanded Product: 207115-22-8).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Recommanded Product: 207115-22-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Regioselective iodination of arenes using iodine/NaBO₃.4H₂O system in ionic liquid was written by Bhilare, Sachin V.;Deorukhkar, Amol R.;Darvatkar, Nitin B.;Salunkhe, Manikrao M.. And the article was included in Synthetic Communications in 2008.Application of 207115-22-8 This article mentions the following:

A mild, efficient, and simple protocol was developed for iodination of arenes and heterocyclic compounds with mol. iodine catalyzed by sodium perborate in ionic liquid The methodol. offered iodoarenes in good to excellent yields at room temperature The protocol proved to be highly selective, as a single isomer was formed exclusively in most of the substrates. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Application of 207115-22-8).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Application of 207115-22-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com