1774-47-6 Archives - Page 8 of 10 - Iodides-buliding-blocks

Varshnaya, Rohit Kumar’s team published research in Journal of Organic Chemistry in 2019 | CAS: 1774-47-6

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Computed Properties of C3H9IOS

In 2019,Journal of Organic Chemistry included an article by Varshnaya, Rohit Kumar; Banerjee, Prabal. Computed Properties of C3H9IOS. The article was titled 《Lewis Acid-Catalyzed [3+3] Annulation of Donor-Acceptor Cyclopropanes and Indonyl Alcohols: One Step Synthesis of Substituted Carbazoles with Promising Photophysical Properties》. The information in the text is summarized as follows:

A highly efficient protocol to access carbazole from donor-acceptor cyclopropane and indonyl alc. via [3+3] annulation in the presence of a Lewis acid has been demonstrated. This method facilitates the post functionalization of the substituted carbazole into a fully conjugated π-system exhibiting intense emission bands in the visible range of the spectrum and also offers a convenient route toward the synthesis of pityriazole derivatives The experimental part of the paper was very detailed, including the reaction process of Trimethylsulfoxonium iodide(cas: 1774-47-6Computed Properties of C3H9IOS)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bozo, Eva’s team published research in Bioorganic & Medicinal Chemistry Letters in 2020 | CAS: 1774-47-6

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Safety of Trimethylsulfoxonium iodide

《New V1a receptor antagonist. Part 2. Identification and optimization of triazolobenzazepines》 was written by Bozo, Eva; Baska, Ferenc; Lovei, Klara; Szanto, Gabor; Domany-Kovacs, Katalin; Kurko, Dalma; Szondine Kordas, Krisztina; Szokoli, Teodora; Bata, Imre. Safety of Trimethylsulfoxonium iodideThis research focused onvasopressin V1a antagonist HTS synthesis triazolobenzazepines; Antagonist; HTS; Synthesis; Triazolobenzazepines; V1a; Vasopressin. The article conveys some information:

Solid preclin. evidence links vasopressin to social behavior in animals, so, extensive work has been initiated to find new vasopressin V1a receptor antagonists which can improve deteriorated social behavior in humans and can treat the core symptoms of autistic behavior, as well. Our aim was to identify new chem. entities with antagonizing effects on vasopressin V1a receptors. Continuing our previous work, we found an in vitro and in vivo orally active V1a selective antagonist mol. (40) among [1,2,4]triazolo[4,3-a][1]benzazepines. In the experimental materials used by the author, we found Trimethylsulfoxonium iodide(cas: 1774-47-6Safety of Trimethylsulfoxonium iodide)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lee, Ga Yeon’s team published research in European Journal of Inorganic Chemistry in 2020 | CAS: 1774-47-6

《Synthesis and Structure of Tin and Germanium Complexes as Precursors Containing Alkoxyaminoalkoxide Ligands for Thin Film Transistors》 was published in European Journal of Inorganic Chemistry in 2020. These research results belong to Lee, Ga Yeon; Lee, Ji Hun; Han, Seong Ho; Park, Bo Keun; Son, Seung Uk; Kim, Chang Gyoun; Jeon, Dong Ju; Chung, Taek-Mo. HPLC of Formula: 1774-47-6 The article mentions the following:

This paper describes the preparation of four novel Sn and Ge complexes containing alkoxyaminoalkoxide type ligands {L1H = 1-[methoxy(methyl)amino]-2-methylpropan-2-ol; L2H = 1-[methoxy(methyl)amino]-2-methylbutan-2-ol} for potential use as precursors for thin film transistors. All compounds were prepared at room temperature by stirring a solution containing Sn(btsa)2 [btsa = bis(trimethylsilyl)amide] or Ge(btsa)2 with two equivalent of L1H or L2H to form Sn(L1)2 (1), Sn(L2)2 (2), Ge(L1)2 (3) and Ge(L2)2 (4). All of the complexes were characterized by NMR and FTIR spectroscopy as well as elemental and thermogravimetric analyses. When the more sym. and compact ligand L1H was applied, solid products 1 and 3 were generated and their structures were studied using x-ray diffraction. Applying the strategy of ligand design at the mol. level, the sym. ligand was changed to an asym. one, replacing one of the two neighboring Me groups of the amino alc. group with an Et group, and forming liquid complexes 2 and 4 for both metals. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6HPLC of Formula: 1774-47-6) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Saha, Debarshi’s team published research in European Journal of Organic Chemistry in 2021 | CAS: 1774-47-6

Saha, Debarshi; Maajid Taily, Irshad; Banerjee, Prabal published their research in European Journal of Organic Chemistry in 2021. The article was titled 《Electricity Driven 1,3-Oxohydroxylation of Donor-Acceptor Cyclopropanes: a Mild and Straightforward Access to β-Hydroxy Ketones》.Reference of Trimethylsulfoxonium iodide The article contains the following contents:

An unprecedented external oxidant-free electrochem. protocol for 1, 3-oxohydroxylation of donor-acceptor cyclopropanes is disclosed. The strategy encompasses the activation of the labile π-electron cloud of the aryl ring to cleave the strained Csp3-Csp3 bond of cyclopropane to afford the β-hydroxy ketones via insertion of mol. oxygen. More significantly, based on the detailed mechanistic investigations and cyclic voltammetry experiments, a plausible mechanism is proposed. The experimental part of the paper was very detailed, including the reaction process of Trimethylsulfoxonium iodide(cas: 1774-47-6Reference of Trimethylsulfoxonium iodide)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Park, Hyowon’s team published research in Bulletin of the Korean Chemical Society in 2019 | CAS: 1774-47-6

COA of Formula: C3H9IOSIn 2019 ,《Multifunctionalization of Indoles: Synthesis of 3-Iodo-2-sulfonyl Indoles》 was published in Bulletin of the Korean Chemical Society. The article was written by Park, Hyowon; Bae, Junryeol; Son, Soobin; Jang, Hye-Young. The article contains the following contents:

The selective multifunctionalization of indoles by using thiosulfonates, tri-Me sulfoxonium iodide (Me3SOI), and H2O2 was studied. The reaction of thiosulfonates with Me3SOI and H2O2 produced sulfonyl radicals and an iodination reagent, both of which were incorporated in indoles to form 3-iodo-2-sulfonyl indoles under carefully controlled conditions. The related reaction mechanism and the substrate scope of 3-iodo-2-sulfonyl indoles are presented. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6COA of Formula: C3H9IOS) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Beck, Kasper’s team published research in Bioorganic & Medicinal Chemistry Letters in 2019 | CAS: 1774-47-6

In 2019,Bioorganic & Medicinal Chemistry Letters included an article by Beck, Kasper; Reslow-Jacobsen, Charlotte; Hornum, Mick; Henriksen, Christian; Nielsen, Poul. Application of 1774-47-6. The article was titled 《A double-headed nucleotide with two cytosines: DNA with condensed information and improved duplex stability》. The information in the text is summarized as follows:

Double-headed nucleotide monomers are capable of condensing the genetic information of DNA. Herein, a double-headed nucleotide with two cytosine bases (CC) is constructed. The addnl. cytosine is connected through a methylene linker to the 2′-position of arabinocytidine. The nucleotide is incorporated into oligonucleotides and its effect on duplex stability is studied. For single incorporations, a thermal stabilization of 4.0 °C is found as compared to the unmodified duplex and it is shown that both nucleobases of CC participate in Watson-Crick base pairing. In combination with the previously published UT monomer, it is also shown that multiple incorporations are tolerated. For instance, a 16-mer sequence is targeted by a 13-mer oligonucleotide by using one CC and two UT monomers without compromising the overall duplex stability. Finally, the potential of double-headed nucleotides in triplex-forming oligonucleotides is studied, however, with the conclusion that the present design is not well-suited for this function.Trimethylsulfoxonium iodide(cas: 1774-47-6Application of 1774-47-6) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Clare, Daniel’s team published research in Angewandte Chemie, International Edition in 2019 | CAS: 1774-47-6

In 2019,Angewandte Chemie, International Edition included an article by Clare, Daniel; Dobson, Benjamin C.; Inglesby, Phillip A.; Aissa, Christophe. HPLC of Formula: 1774-47-6. The article was titled 《Chemospecific Cyclizations of α-Carbonyl Sulfoxonium Ylides on Aryls and Heteroaryls》. The information in the text is summarized as follows:

The functionalization of aryl and heteroaryls using α-carbonyl sulfoxonium ylides without the help of a directing group has remained so far a neglected area, despite the advantageous safety profile of sulfoxonium ylides (safety: an α-diazo ketone was potentially explosive, whereas an α-carbonyl sulfoxonium ylide was not). Described herein are the cyclizations of α-carbonyl sulfoxonium ylides onto benzenes, benzofurans and N-p-toluenesulfonyl indoles in the presence of a base in HFIP [e.g., I → II (91%) in presence of K2CO3 in HFIP], whereas pyrroles and N-Me indoles undergo cyclization in the presence of an iridium catalyst. Significantly, these two sets of conditions are chemospecific for each groups of substrates. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6HPLC of Formula: 1774-47-6) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cabre, Albert’s team published research in Angewandte Chemie, International Edition in 2020 | CAS: 1774-47-6

《Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols》 was written by Cabre, Albert; Rafael, Sergi; Sciortino, Giuseppe; Ujaque, Gregori; Verdaguer, Xavier; Lledos, Agusti; Riera, Antoni. Electric Literature of C3H9IOS And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

The selective isomerization of strained heterocyclic compounds is an important tool in organic synthesis. An unprecedented regioselective isomerization of 2,2-disubstituted oxetanes into homoallylic alcs. is described. The use of tris(pentafluorophenyl)borane (B(C6F5)3), a com. available Lewis acid was key to obtaining good yields and selectivities since other Lewis acids afforded mixtures of isomers and substantial polymerization The reaction took place under exceptionally mild reaction conditions and very low catalyst loading (0.5 mol %). DFT calculations disclose the mechanistic features of the isomerization and account for the high selectivity displayed by the B(C6F5)3 catalyst. The synthetic applicability of the new reaction is demonstrated by the preparation of γ-chiral alcs. using iridium-catalyzed asym. hydrogenation. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6Electric Literature of C3H9IOS)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Unnava, Ramanjaneyulu’s team published research in Organic & Biomolecular Chemistry in 2021 | CAS: 1774-47-6

Unnava, Ramanjaneyulu; Chahal, Kapil; Reddy, Kallu Rajender published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Synthesis of substituted 1,2-dihydroisoquinolines via Ni(II) and Cu(I)/Ag(I) catalyzed double nucleophilic addition of arylamines to ortho-alkynyl donor-acceptor cyclopropanes (o-ADACs)》.Synthetic Route of C3H9IOS The article contains the following contents:

A concise approach for the synthesis of substituted 1,2-dihydroisoquinolines via double nucleophilic addition of primary arylamines to ortho-alkynyl donor-acceptor cyclopropanes (o-ADACs) in the presence of a catalytic Ni(ClO4)2·6H2O and CuI/AgOTf system has been developed. Further applying this protocol, some of the derived malonates were converted into the corresponding monoesters under Krapcho decarboxylation reaction conditions. Thereafter, these esters were transformed into the resp. acids and alcs. In addition, multifunctionalized 4-(2,2,2-trifluoroacetyl) 1,2-dihydroisoquinolines were also obtained with excess TFAA. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Mengyuan’s team published research in Angewandte Chemie, International Edition in 2021 | CAS: 1774-47-6

Chen, Mengyuan; Liang, Yuchen; Dong, Taotao; Liang, Weijian; Liu, Yanping; Zhang, Yage; Huang, Xin; Kong, Lichun; Wang, Zhi-Xiang; Peng, Bo published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Z-Selective α-Arylation of α,β-Unsaturated Nitriles via [3,3]-Sigmatropic Rearrangement》.Category: iodides-buliding-blocks The article contains the following contents:

The Morita-Baylis-Hillman (MBH) reaction and [3, 3]-sigmatropic rearrangement are two paradigms in organic synthesis. We have merged the two types of reactions to achieve [3,3]-rearrangement of aryl sulfoxides with α,β-unsaturated nitriles. The reaction was achieved by sequentially treating both coupling partners with electrophilic activator (Tf2O) and base, offering an effective approach to prepare synthetically versatile α-aryl α,β-unsaturated nitriles with Z-selectivity through direct α-C-H arylation of unmodified α,β-unsaturated nitriles. The control experiments and DFT calculations support a four-stage reaction sequence, including the assembly of Tf2O activated aryl sulfoxide with α,β-unsaturated nitrile, MBH-like Lewis base addition, [3,3]-rearrangement, and E1cB-elimination. Among these stages, the Lewis base addition is diastereoselective and E1cB-elimination is cis-selective, which could account for the remarkable Z-selectivity of the reaction. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com