Category: 1774-47-6

Lee, Seung Cheol; Son, Jeong-Yu; Kim, Jin Young; Eom, Hyeonsik; Jang, Seong Bin; Lee, Phil Ho published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Regioselective and Chemodivergent Synthesis of Azulenolactones and Azulenolactams from Rhodium(III)-Catalyzed Reactions of Azulenecarboxamides with Sulfoxonium Ylides》.Product Details of 1774-47-6 The article contains the following contents:

A regioselective and chemodivergent synthetic approach for azulenolactones I (R1 = H, 8-Me, 8-Ph; R2 = H, Cl, Me; R3 = Ph, 3-MeC6H4, 4-ClC6H4, etc.; R4 = H, Me, Ph, 3-MeOC6H4) and azulenolactams II (R1 = H, 8-Me; R2 = H, Cl, Me; R3 = nBu, Ph, 3-MeC6H4, etc.; R4 = H, Me, Ph, 3-MeOC6H4) as a new scaffold was demonstrated through Rh(III)-catalyzed reaction of N-methoxyazulene-1-carboxamides with sulfoxonium ylides. Sulfoxonium ylides that act as a precursor of secondary carbene was described, leading to the selective formation of azulenolactones and azulenolactams bearing two substituents on a newly introduced double bond. This method demonstrated functionalization of less reactive 2-position of azulene to overcome the natural reactivity. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Product Details of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 1774-47-6In 2021 ,《Lewis acid-catalyzed [3 + 2] annulations of oxindole based spirocyclic donor-acceptor cyclopropanes with ynamides》 was published in Organic & Biomolecular Chemistry. The article was written by Zhang, Dongxin; Cheng, Qihang; Chen, Lvjia; Deng, Huiqing; Cai, Hu; Zhang, Qian-Feng. The article contains the following contents:

The [3 + 2] annulations of oxindole based spirocyclic donor-acceptor cyclopropanes and ynamides catalyzed by copper triflate was developed for the synthesis of biol. important spirocyclopenteneoxindoles. These reactions tolerated a wide scope of substrates and provided the desired products in good to high yields (up to 90%) with up to >40 : 1 diastereoselectivities under mild conditions.Trimethylsulfoxonium iodide(cas: 1774-47-6Related Products of 1774-47-6) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Related Products of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Chinese Journal of Structural Chemistry included an article by Hui, Jia; Zhong, Han-Yu; Zhang, Jing-Yi. COA of Formula: C3H9IOS. The article was titled 《Synthesis, crystal structure and bioactivity of ethyl 1 1-((2 2-Bromophenyl)carbamoyl) carbamoyl)-2-(3,4,5 3,4,5- trimethoxyphenyl)cyclopropanecarboxylate》. The information in the text is summarized as follows:

Many small-mol. compounds were reported as microtubule-inhibitor with potential anticancer activities, such as combretastatin-A4 (CA-4) analog. The title compound which is one novel cyclopropylamide analog of CA-4, namely as Et 1-((2-bromophenyl)car- bamoyl)-2-(3,4,5-trimethoxyphenyl)cyclopropanecarboxylate, has been synthesized and its crystal structure was characterized by X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 8.8002 ( 6), b = 11.4525(8), c = 21.7870(16) Å, beta = 93.810(3)°, V = 2190.9(3) Å3, Z = 4, C22H23BrNO6, Mr = 477.32477.32, Dc = 1. 447 Mg /cm3, F(000) = 980, (CuKa) = 1.54178 Å, mu = 2.883 mm-1, R = 0.0691 and wR = 0.1958 for 6420 observed reflections (I > 2s(I)). Importantly, the compound revealed potential anticancer activities in six cancer cells and could stimulate tubulin polymerization in vitro, indicating that the small-mol. could be selected as a lead compound for the development of microtubule stimulator. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6COA of Formula: C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.COA of Formula: C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Fadeev, Alexander A.; Makarov, Anton S.; Ivanova, Olga A.; Uchuskin, Maxim G.; Trushkov, Igor V. published an article in Organic Chemistry Frontiers. The title of the article was 《Extended Corey-Chaykovsky reactions: transformation of 2-hydroxychalcones to benzannulated 2,8-dioxabicyclo[3.2.1]octanes and 2,3-dihydrobenzofurans》.Product Details of 1774-47-6 The author mentioned the following in the article:

The divergent synthesis of benzannulated 2,8-dioxabicyclo[3.2.1]octanes I [R1 = H, 4-NO2, 4-Cl, etc.; R2 = Ph, 4-MeC6H4, 4-FC6H4, etc.] and 2,3-dihydrobenzofurans II [X= H, 4-NO2, 4-Cl, etc.; R1 = Ph, 4-MeC6H4, 4-FC6H4, etc.] using the concept of extended Corey-Chaykovsky reactions was reported. With this concept, 2-hydroxychalcones were treated with the Corey ylide providing highly reactive donor-acceptor cyclopropanes that were introduced in a one pot manner for further transformations. We demonstrated that the nucleophilic three-membered ring opening followed by cyclization under mild reaction conditions afforded the 2,8-dioxabicyclo[3.2.1]octane scaffold. On the other hand, heating the intermediates with a strong Bronsted acid furnished 2-phenacyl-2,3-dihydrobenzofurans. These transformations, resulting in products with crucially different heterocyclic skeletons from the same starting compounds, demonstrate the enormous potential of the extended Corey-Chaykovsky reaction.Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Product Details of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Quality Control of Trimethylsulfoxonium iodideIn 2020 ,《Double-headed nucleotides as xeno nucleic acids: information storage and polymerase recognition》 was published in Organic & Biomolecular Chemistry. The article was written by Beck, Kasper M.; Krogh, Marie B.; Hornum, Mick; Ludford, Paul T.; Tor, Yitzhak; Nielsen, Poul. The article contains the following contents:

Xeno nucleic acids (XNAs) are artificial genetic systems based on sugar-modified nucleotides. Herein, we investigate double-headed nucleotides as a new XNA. A new monomer, AT, is presented, and together with previous double-headed nucleotide monomers, new nucleic acid motifs consisting of up to five consecutive A·T base pairs have been obtained. Sections composed entirely of double-headed nucleotides are well-tolerated within a DNA duplex and can condense the genetic information. For instance, a 13-mer duplex is condensed to an 11-mer modified duplex containing four double-headed nucleotides while simultaneously improving duplex thermal stability with +14.0°C. Also, the transfer of information from double-headed to natural nucleotides by DNA polymerases has been examined The first double-headed nucleoside triphosphate was prepared but could not be recognized and incorporated by the tested DNA polymerases. On the other hand, it proved possible for Therminator DNA polymerase to transfer the information of a double-headed nucleotide in a template sequence to natural DNA under controlled conditions. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Quality Control of Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Quality Control of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Ring Opening of Donor-Acceptor Cyclopropanes with Cyanide Ion and Its Surrogates》 was written by Boichenko, Maksim A.; Andreev, Ivan A.; Chagarovskiy, Alexey O.; Levina, Irina I.; Zhokhov, Sergey S.; Trushkov, Igor V.; Ivanova, Olga A.. Computed Properties of C3H9IOS And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

A straightforward method for ring opening of donor-acceptor cyclopropanes with trimethylsilyl cyanide as a surrogate of cyanide ion in the presence of B(C6F5)3 or trifluoromethanesulfonic acid as a catalyst has been developed. The methodol. provides a short route to gamma-cyanoesters that can be useful synthetic intermediates for the synthesis of diverse bioactive mols. such as glutaric and delta-aminovaleric acid derivatives, 3-arylpiperidines or other substituted phenethylamines. Oppositely, the attempts to synthesize these gamma-cyanoesters by direct reaction of cyclopropanes with sodium cyanide under typical SN2 conditions led to the formation of 2-arylsuccinonitriles. The experimental part of the paper was very detailed, including the reaction process of Trimethylsulfoxonium iodide(cas: 1774-47-6Computed Properties of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Computed Properties of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Kun; Studer, Armido published their research in Journal of the American Chemical Society in 2021. The article was titled 《Direct α-Acylation of Alkenes via N-Heterocyclic Carbene, Sulfinate, and Photoredox Cooperative Triple Catalysis》.Name: Trimethylsulfoxonium iodide The article contains the following contents:

N-Heterocyclic carbene (NHC) catalysis has emerged as a versatile tool in modern synthetic chem. Further increasing the complexity, several processes have been introduced that proceed via dual catalysis, where the NHC organocatalyst operates in concert with a second catalytic moiety, significantly enlarging the reaction scope. In biol. transformations, multiple catalysis is generally used to access complex natural products. Guided by that strategy, triple catalysis has been studied recently, where three different catalytic modes are merged in a single process. In this Communication, direct α-C-H acylation of various alkenes with aroyl fluorides using NHC, sulfinate, and photoredox cooperative triple catalysis is reported. The method allows the preparation of α-substituted vinyl ketones in moderate to high yields with excellent functional group tolerance. Mechanistic studies reveal that these cascades proceed through a sequential radical addition/coupling/elimination process. In contrast to known triple catalysis processes that operate via two sets of interwoven catalysis cycles, in the introduced process, all three cycles are interwoven. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Name: Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Name: Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pipitone, Candida; Giannici, Francesco; Martorana, Antonino; Garcia-Espejo, Gonzalo; Carlotto, Silvia; Casarin, Maurizio; Guagliardi, Antonietta; Masciocchi, Norberto published their research in Journal of Physical Chemistry C in 2021. The article was titled 《Heterovalent BiIII/PbII Ionic Substitution in One-Dimensional Trimethylsulfoxonium Halide Pseudo-Perovskites (X = I, Br)》.Application of 1774-47-6 The article contains the following contents:

The authors report on the synthesis and characterization of novel lead and Bi hybrid (organic-inorganic) iodide and bromide pseudo-perovskites (ABX3) containing the trimethylsulfoxonium cation Me3SO+ (TMSO) in the A site, Pb/Bi in the B site, and Br or I as X anions. All of these compounds are isomorphic and crystallize in the orthorhombic Pnma space group. Pb-based pseudo-perovskites consist of 1-dimensional (1D) chains of face-sharing [PbX6] octahedra, while in the Bi-based ones, the chains of [BiX6] are interrupted, with one vacancy every 3rd site, leading to a zero-dimensional (0-D) local structure based on separated [Bi2I9]3- dimers. Five solid solutions for the iodide with different Pb2+/Bi3+ ratios between (TMSO)PbI3 and (TMSO)3Bi2I9, and two for the bromide counterparts, were synthesized. Due to the charge compensation mechanism, these systems are best described by the (TMSO)3Pb3xBi2(1-x)I9 (x = 0.98, 0.92, 0.89, 0.56, and 0.33) and (TMSO)3Pb3xBi2(1-x)Br9 (x = 0.83 and 0.37) formulas. X-ray powder diffraction (XRPD) measurements were employed to determine the crystal structure of all studied species and further used to test the metal cation miscibility within monophasic samples not showing cation segregation. These systems can be described through an ionic defectivity on the pseudo-perovskite B site, where the Pb2+/Bi3+ replacement is compensated by one Pb2+ vacancy for every Bi3+ pair. This leads to a wide range of possible different (numerical and geometrical) chain configurations, leading to the unique features observed in XRPD patterns. The optical band gap of the iodide samples falls in the 2.11-2.74 eV range and decreases upon increasing the Bi3+ content. Even a very low loading of Bi3+ (1%) is sufficient to reduce the band gap substantially from 2.74 to 2.25 eV. Periodic d. functional theory (DFT) calculations were used to simulate the at. and electronic structures of the authors’ samples, with predicted band gap trends in good agreement with the exptl. ones. This work highlights the structural flexibility of such systems and accurately interprets the ionic defectivity of the different pseudo-perovskite structures. In the experimental materials used by the author, we found Trimethylsulfoxonium iodide(cas: 1774-47-6Application of 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Application of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Parashar, Mritunjaya; Singh, Ranbir; Yoo, Kicheon; Lee, Jae-Joon published an article in 2021. The article was titled 《Formation of 1-D/3-D Fused Perovskite for Efficient and Moisture Stable Solar Cells》, and you may find the article in ACS Applied Energy Materials.Category: iodides-buliding-blocks The information in the text is summarized as follows:

Various organic cations (e.g., methylammonium (MA+), butylammonium (BA+), formamidinium (FA+), etc.) have been studied and used in organometallic halide perovskite solar cells (PSCs). Most of the currently used organic cations are protic in nature, which can induce acid-base reactions and, thus, lead to degradation of the perovskites. So far, the role of aprotic cations in PSCs has not been studied much. In the present study, two aprotic cations, namely, trimethylsulfonium (TMS+) and trimethylsulfoxonium (TMSO+), are introduced into lead-based PSCs to form one-dimensional/three-dimensional (TMSPbI3)x(MAPbI3)100-x and (TMSOPbI3)x(MAPbI3)100-x perovskite structures, resp. This is shown to provide enhanced performance and moisture resistance, thus, increasing the stability and lifespan of the PSCs. The power conversion efficiencies of the (TMSPbI3)x(MAPbI3)100-x and (TMSOPbI3)x(MAPbI3)100-x devices are found to be 19.34 and 19.94%, resp., compared to 17.11% for the pristine MAPbI3 PSC, along with enhanced open-circuit voltages (VOC) of 1.14 and 1.12 V, resp., compared to 1.07 V for the pristine MAPbI3 PSC. Furthermore, the effects of TMS+ and TMSO+ upon the perovskite structure, absorption, recombination, and film morphol. are discussed in detail. The results of this study will be helpful in the exploration of sulfur-based cations for the development of more stable PSCs. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Donor-Acceptor Bicyclopropyls as 1,6-Zwitterionic Intermediates: Synthesis and Reactions with 4-Phenyl-1,2,4-triazoline-3,5-dione and Terminal Acetylenes》 was published in Journal of Organic Chemistry in 2020. These research results belong to Potapov, Konstantin V.; Denisov, Dmitry A.; Glushkova, Valeriia V.; Novikov, Roman A.; Tomilov, Yury V.. Recommanded Product: 1774-47-6 The article mentions the following:

The bicyclopropyl system activated by incorporation of donor and acceptor groups in the presence of Lewis acids was used as a synthetic equivalent of 1,6-zwitterions. Opening of both cyclopropane rings in 2′-aryl-1,1′-bicyclopropyl-2,2-dicarboxylates (D-A bicyclopropyl, ABCDs) in the presence of GaI3 + Bu4N+GaI4- results in 5-iodo-5-arylpent-2-enylmalonates as products of HI formal 1,6-addition to the bicyclopropyl system. The use of GaCl3 or GaBr3 as a Lewis acid and terminal aryl or alkyl acetylenes as 1,6-zwitterion interceptors allows the alkyl substituent to be grown to give the corresponding acyclic 7-chloro(bromo)-hepta-2,6-dienylmalonates. The reaction of ABCDs with 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) catalyzed by Yb(OTf)3 also results in the opening of both cyclopropane rings. The reaction products are tetrahydropyridazine derivatives – (7,9-dioxo-1,6,8-triazabicyclo[4.3.0]non-3-en-2-ylmethyl)malonates – containing one more PTAD moiety in the malonyl group. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Recommanded Product: 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com