1774-47-6 Archives - Page 3 of 10 - Iodides-buliding-blocks

Fadeev, Alexander A.’s team published research in Molecules in 2020 | CAS: 1774-47-6

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Electric Literature of C3H9IOS

《Synthesis of (het)aryl 2-(2-hydroxyaryl)cyclopropyl ketones》 was published in Molecules in 2020. These research results belong to Fadeev, Alexander A.; Chagarovskiy, Alexey O.; Makarov, Anton S.; Levina, Irina I.; Ivanova, Olga A.; Uchuskin, Maxim G.; Trushkov, Igor V.. Electric Literature of C3H9IOS The article mentions the following:

A simple general method for the synthesis of 1-acyl-2-(ortho-hydroxyaryl)cyclopropanes I [R = 5-F, 5-NO2, 3-OMe, etc.; Ar = Ph, 4-OMeC6H4, 2-thienyl], which belong to the donor-acceptor cyclopropane family, was developed. This method, based on the Corey-Chaykovsky cyclopropanation of 2-hydroxychalcones, allowed for the preparation of a large diversity of hydroxy-substituted cyclopropanes, which could serve as promising building blocks for the synthesis of various bioactive compounds In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Electric Literature of C3H9IOS) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Lin-Bao’s team published research in Organic Letters in 2022 | CAS: 1774-47-6

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Quality Control of Trimethylsulfoxonium iodide

In 2022,Zhang, Lin-Bao; Xie, Zuowei published an article in Organic Letters. The title of the article was 《Iridium-Catalyzed Selective B(4)-H Acylmethylation of o-Carboranes with Sulfoxonium Ylides》.Quality Control of Trimethylsulfoxonium iodide The author mentioned the following in the article:

A highly efficient Ir-catalyzed regioselective cage B(4)-H acylmethylation of o-carboranyl acids using sulfoxonium ylides as alkylating regents was developed, giving a large class of B(4)-acylmethylated o-carboranes in good to excellent yields with a broad substrate scope under redox neutral condition. The -COOH moiety serves as the traceless directing group and controls both the regioselectivity and monoselectivity. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Quality Control of Trimethylsulfoxonium iodide)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Jiang, Huanfeng’s team published research in Organic Letters in 2019 | CAS: 1774-47-6

In 2019,Organic Letters included an article by Jiang, Huanfeng; Zhang, Hao; Xiong, Wenfang; Qi, Chaorong; Wu, Wanqing; Wang, Lu; Cheng, Ruixiang. Application In Synthesis of Trimethylsulfoxonium iodide. The article was titled 《Iridium-Catalyzed Three-component Coupling Reaction of Carbon Dioxide, Amines, and Sulfoxonium Ylides》. The information in the text is summarized as follows:

The first iridium-catalyzed three-component coupling reaction of carbon dioxide, amines, and sulfoxonium ylides has been developed, providing an efficient and straightforward method for the construction of a range of structurally diverse O-β-oxoalkyl carbamates, e.g., I (X-rays single crystal structure shown), in moderate to excellent yields. This novel protocol features the use of readily available substrates, wide substrate scope, and good functional group tolerance. Moreover, the phosgene-free strategy was successfully applied to the synthesis of a potential antitumor agent via a a three-step procedure starting from a steroid carboxylic acid. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Application In Synthesis of Trimethylsulfoxonium iodide)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ivanov, Konstantin L.’s team published research in Synthesis in 2020 | CAS: 1774-47-6

《One-Pot Synthesis of γ-Azidobutyronitriles and Their Intramolecular Cycloadditions》 was published in Synthesis in 2020. These research results belong to Ivanov, Konstantin L.; Tukhtaev, Hamidulla B.; Tukhtaeva, Feruza O.; Bezzubov, Stanislav I.; Melnikov, Mikhail Ya.; Budynina, Ekaterina M.. COA of Formula: C3H9IOS The article mentions the following:

Efficient gram-scale, one-pot approached to azidocyanobutyrates and their amidated or decarboxylated derivatives was developed, starting from com. available aldehydes and cyanoacetates. These techniques combine (1) Knoevenagel condensation, (2) Corey-Chaykovsky cyclopropanation and (3) nucleophilic ring opening of donor-acceptor cyclopropanes with the azide ion, as well as (4) Krapcho decarboxylation or (4′) amidation. The synthetic utility of the resulting γ-azidonitriles was demonstrated by their transformation into tetrazoles via intramol. (3+2)-cycloaddition A condition-dependent activation effect of the α-substituent was revealed in that case. Thermally activated azide-nitrile interaction did not differentiate the presence of an α-electron-withdrawing substituent in γ-azidonitriles, whereas the Lewis acid mediated (SnCl4or TiCl4) reaction proceeded much easier for azidocyanobutyrates. This allowed us to develop an efficient procedure for converting azidocyanobutyrates into the corresponding tetrazoles. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6COA of Formula: C3H9IOS)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liang, Yong-Xin’s team published research in Organic Letters in 2020 | CAS: 1774-47-6

《Silver-Catalyzed Cascade Cyclization Reaction of Isocyanides with Sulfoxonium Ylides: Synthesis of 3-Aminofurans and 4-Aminoquinolines》 was written by Liang, Yong-Xin; Yang, Ming; He, Bo-Wen; Zhao, Yu-Long. SDS of cas: 1774-47-6 And the article was included in Organic Letters in 2020. The article conveys some information:

A silver-catalyzed cascade cyclization reaction of isocyanides with sulfoxonium ylides has been developed for the first time. This reaction provides a new and efficient method for the construction of highly functionalized 3-aminofurans and 4-aminoquinolines from readily available starting materials in a single step. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6SDS of cas: 1774-47-6)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mishra, Uttam K.’s team published research in Organic Letters in 2019 | CAS: 1774-47-6

In 2019,Organic Letters included an article by Mishra, Uttam K.; Patel, Kaushalendra; Ramasastry, S. S. V.. Name: Trimethylsulfoxonium iodide. The article was titled 《Synthesis of Cyclopropanoids via Substrate-Based Cyclization Pathways》. The information in the text is summarized as follows:

A series of unexpected reactions triggered by the dimethyloxosulfonium methylide led to the discovery of unconventional approaches for the synthesis of cyclopropa-fused tetralones and indeno-spirocyclopropanes. These highly functionalized structures were further elaborated in one step to privileged scaffolds such as tetralones, indenones, and fluorenones. As a whole, the results presented herein establish new diversity-oriented folding pathways. In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Name: Trimethylsulfoxonium iodide)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Combee, Logan A.’s team published research in Organic Letters in 2019 | CAS: 1774-47-6

The author of 《Rh(II)-Catalyzed Nitrene-Transfer [5 + 1] Cycloadditions of Aryl-Substituted Vinylcyclopropanes》 were Combee, Logan A.; Johnson, Shea L.; Laudenschlager, Julie E.; Hilinski, Michael K.. And the article was published in Organic Letters in 2019. Quality Control of Trimethylsulfoxonium iodide The author mentioned the following in the article:

Formal [5 + 1] cycloadditions between aryl-substituted vinylcyclopropanes and nitrenoid precursors are reported. The method, which employs Rh2(esp)2 as a catalyst, leads to the highly regioselective formation of substituted tetrahydropyridines. Preliminary mechanistic studies support a stepwise, polar mechanism enabled by the previously observed Lewis acidity of Rh-nitrenoids. Overall, this work expands the application of nitrene-transfer cycloaddition, a relatively underexplored approach to heterocycle synthesis, to the formation of six-membered rings. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Quality Control of Trimethylsulfoxonium iodide) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Faltracco, Matteo’s team published research in Organic Letters in 2021 | CAS: 1774-47-6

Faltracco, Matteo; Damian, Matteo; Ruijter, Eelco published an article in 2021. The article was titled 《Synthesis of Carbazoles and Dihydrocarbazoles by a Divergent Cascade Reaction of Donor-Acceptor Cyclopropanes》, and you may find the article in Organic Letters.Recommanded Product: Trimethylsulfoxonium iodide The information in the text is summarized as follows:

An alkylation/olefination cascade of indolecarboxaldehydes and phosphonate-functionalized donor-acceptor cyclopropanes affords functionalized dihydrocarbazoles and cyclohepta[cd]indoles in formal [3 + 3] and [4 + 3]-cycloadditions A minor modification to the reaction conditions also allowed access to the fully aromatic heterocyclic scaffolds by thermal loss of an electron-rich aryl moiety.Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: Trimethylsulfoxonium iodide) was used in this study.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Schmalz, Veronika’s team published research in Organic Letters in 2022 | CAS: 1774-47-6

In 2022,Schmalz, Veronika; Koert, Ulrich published an article in Organic Letters. The title of the article was 《Visible-Light Induced Photoannulation of α-Naphthyl Cyclopropane Carboxylic Esters to Functionalized Dihydrophenalenes》.Synthetic Route of C3H9IOS The author mentioned the following in the article:

A general synthetic entry to functionalized dihydrophenalenes was founded using naphthyl-cyclopropane esters as starting materials. The desired annulation were possible with visible light, Ir(Fppy)3 as photocatalyst and BnNMe2 or DABCO as electron donor, HAT-catalyst and proton source. A broad scope of substituted naphthyl and azanaphthyl derivatives provided the photoannulation products in high yield. Deuteration studies supported a photoredox-mechanism involved the photoreductive cyclopropane opening to an enolate radical followed by an aryl radical trapping. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ortega, Alesandere’s team published research in Organic Letters in 2021 | CAS: 1774-47-6

《Bronsted Acid Catalyzed (4 + 2) Cyclocondensation of 3-Substituted Indoles with Donor-Acceptor Cyclopropanes》 was written by Ortega, Alesandere; Uria, Uxue; Tejero, Tomas; Prieto, Liher; Reyes, Efraim; Merino, Pedro; Vicario, Jose L.. Product Details of 1774-47-6 And the article was included in Organic Letters in 2021. The article conveys some information:

Acylcyclopropanes are employed as useful donor-acceptor cyclopropanes that undergo formal (4 + 2) cyclocondensation with N-unprotected 3-substituted indoles in the presence of a Bronsted acid catalyst. The reaction involves the simultaneous alkylation of both the N and C-2 positions of the indole and provides access to the 8,9-dihydropyrido[1,2-a]indole scaffold that is the central core of several biol. relevant indole alkaloids in excellent yields and good selectivities. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com