Category: 1774-47-6

In 2022,Hosseini, S. Sina; Abdi, Aida; Nikbakht, Ali; Bijanzadeh, Hamid Reza; Rominger, Frank; Werz, Daniel B.; Balalaie, Saeed published an article in Synlett. The title of the article was 《Hydrothiolation of Donor-Acceptor Cyclopropanes through Er(OTf)3-Promoted Three-Component Ring-Opening Reaction》.COA of Formula: C3H9IOS The author mentioned the following in the article:

A novel ring-opening reaction of donor-acceptor cyclopropanes (DACs) I (R = Ph, 2-phenylethenyl, furan-2-yl, etc.) through a one-pot three-component nucleophilic addition of amines R1R2NH [R1 = R2 = CH2CH=CH2, CH2CH3; R1R2 = -(CH2)5-, -(CH2)2O(CH2)2-, -(CH2)2N(CH3)(CH2)2-], CS2, and DACs has been described. New γ-dithiocarbamate dialkyl malonate skeletons R1R2C(S)SCH(R)CH2CH((C(O)OR1)2) were obtained in up to 97% yield. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6COA of Formula: C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.COA of Formula: C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Organic Letters included an article by Lou, Jiang; Wang, Quannan; Zhou, Yong-Gui; Yu, Zhengkun. Category: iodides-buliding-blocks. The article was titled 《Rhodium(III)-Catalyzed Annulative Coupling of Sulfoxonium Ylides and Allenoates: An Arene C-H Activation/Cyclopropanation Cascade》. The information in the text is summarized as follows:

Rhodium(III)-catalyzed annulative coupling of sulfoxonium ylides with allenoates was achieved, forming highly functionalized cyclopropanes I (R1 = H, 3-F, 5-Me, etc.; R2 = Me, nBu, Bn, etc.; R3 = Et, iPr, Ph, etc.) with a quaternary carbon center by means of the sulfoxonium ylide functionality as a traceless bifunctional directing group and C4 synthon via an arene C-H activation and cyclopropanation cascade. The protocol features simultaneous formation of three new C-C bonds in one pot with excellent diastereoselectivity. The resultant cyclopropanation products could be further transformed to diverse synthetically useful compounds In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Copper-Catalyzed Annulation or Homocoupling of Sulfoxonium Ylides: Synthesis of 2,3-Diaroylquinolines or α,α,β-Tricarbonyl Sulfoxonium Ylides》 was published in Organic Letters in 2020. These research results belong to Zhu, Shuai; Shi, Kai; Zhu, Hao; Jia, Zhe-Kang; Xia, Xiao-Feng; Wang, Dawei; Zou, Liang-Hua. Name: Trimethylsulfoxonium iodide The article mentions the following:

An unprecedented copper-catalyzed reaction of sulfoxonium ylides and anthranils was reported that enabled an easy access to 2,3-diaroylquinolines I [R = H, 6-F, 7-Cl, etc.; R1 = Ph, 2-thiophenyl, 4-MeC6H4, etc.] through a [4+1+1] annulation. Copper-catalyzed homocoupling of sulfoxonium ylides provided α,α,β-tricarbonyl sulfoxonium ylides II, which provided a strategy to extend the carbon chain through C-C bond formation. The utility of the products as well as the mechanistic details of the process were presented. In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Name: Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Name: Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Rhodium-Catalyzed Reaction of Sulfoxonium Ylides and Anthranils toward Indoloindolones via a (4 + 1) Annulation》 were Wu, Xiaopeng; Xiao, Yan; Sun, Song; Yu, Jin-Tao; Cheng, Jiang. And the article was published in Organic Letters in 2019. SDS of cas: 1774-47-6 The author mentioned the following in the article:

A rhodium-catalyzed annulation between aroyl sulfoxonium ylides and anthranils has been developed to synthesize 10H-indolo[1,2-a]indol-10-one derivatives This reaction started with an unprecedented (4 + 1) annulation toward N-(2-formylphenyl) indolones, proceeding with the sequential ortho-amination of the C-H bond in aroyl sulfoxonium ylides by anthranils and the insertion of N-H to carbene. Finally, the Aldol condensation constructed the second indole ring. This procedure features the formation of two C-N bonds and one C=C bond in one pot. The results came from multiple reactions, including the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6SDS of cas: 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.SDS of cas: 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction》 were Shen, Zuyuan; Zhang, Shilei; Geng, Huihui; Wang, Jiarui; Zhang, Xinyu; Zhou, Anqi; Yao, Cheng; Chen, Xiaobei; Wang, Wei. And the article was published in Organic Letters in 2019. Product Details of 1774-47-6 The author mentioned the following in the article:

A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d6 is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d6 and directly used for subsequent trideuteromethylation in a “”one-pot”” operation. The preparative power of the new versatile reagent and the “”one-pot”” protocol is demonstrated by its use to install the -CD3 moiety into broad functionalities including phenols, thiophenols, acidic amines, and enolizable methylene units in high yield and at a useful level of deuteration (>87% D). In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Product Details of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Gao, Yanfeng; Mao, Yuanhao; Miao, Zhiwei published an article in Organic Letters. The title of the article was 《Enantioselective 1,3-Dipolar (5+3) Cycloadditions of Oxidopyrylium Ylides and Vinylcyclopropanes toward 9-Oxabicyclononanes》.Recommanded Product: 1774-47-6 The author mentioned the following in the article:

An efficient and mild enantioselective palladium-catalyzed (5+3) cycloaddition of vinylcyclopropanes and oxidopyrylium ylides generated in situ from benzopyranones was developed, in the presence of a chiral PHOX ligand. These reactions afforded various highly functionalized bridged oxa-[3.3.1]carbocycles I [R = H, Me, Et, n-Bu, i-Bu, CH2-t-Bu; R1 = Me, Et, Ar = Ph, 2-furyl, 2-thienyl, etc.] with three stereogenic centers that were challenging to synthesize, in moderate to good yields and enantioselectivities. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Recommanded Product: 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Dimethyl 2-{[2-(2-methoxy-1-methoxycarbonyl-2- oxoethyl)-4,5,7-trimethoxy-3-(2,4,5-trimethoxyphenyl) -2,3-dihydro-1H-inden-1-yl]methyl}malonate》 was written by Boichenko, Maksim A.; Chagarovskiy, Alexey O.; Rybakov, Victor B.; Trushkov, Igor V.; Ivanova, Olga A.. Recommanded Product: 1774-47-6This research focused ontrimethoxyphenyl cyclopropanediester dimerization; dimethyl trimethoxyphenyl trimethoxyindanyl malonate preparation. The article conveys some information:

A simple synthetic approach to di-Me 2-{[2-(2-methoxy-1-methoxycarbonyl-2-oxoethyl) -4,5,7-trimethoxy-3-(2,4,5-trimethoxyphenyl)-2,3-dihydro-1H-inden-1-yl]methyl}malonate was developed, based on a B(C6F5)3-induced domino dimerization of 2-(2,4,5-trimethoxyphenyl) cyclopropane-1,1-diester. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Recommanded Product: 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Iridium-Catalyzed B-H Bond Insertion Reactions Using Sulfoxonium Ylides as Carbene Precursors toward α-Boryl Carbonyls》 were Li, Jianglian; He, Hua; Huang, Mengyi; Chen, Yuncan; Luo, Yi; Yan, Kaichuan; Wang, Qiantao; Wu, Yong. And the article was published in Organic Letters in 2019. Synthetic Route of C3H9IOS The author mentioned the following in the article:

An Ir-catalyzed B-H bond insertion reaction between borane adducts and sulfoxonium ylides to afford α-boryl carbonyls was developed. The starting materials are safe and readily available. Analogs of sulfoxonium ylides, such as sulfonium salts and sulfonium ylides could also be amenable to the reaction. The experimental part of the paper was very detailed, including the reaction process of Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Synthetic Route of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Palladium-Catalyzed Oxidative Allylation of Sulfoxonium Ylides: Regioselective Synthesis of Conjugated Dienones》 were Li, Chunsheng; Li, Meng; Zhong, Wentao; Jin, Yangbin; Li, Jianxiao; Wu, Wanqing; Jiang, Huanfeng. And the article was published in Organic Letters in 2019. Quality Control of Trimethylsulfoxonium iodide The author mentioned the following in the article:

The first examples of palladium-catalyzed allylic C-H oxidative allylation of sulfoxonium ylides to afford the corresponding conjugated dienones with moderate to good yields have been established. The features of this novel conversion include mild reaction conditions, wide substrate scope, and excellent regioselectivity. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Quality Control of Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Quality Control of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reference of Trimethylsulfoxonium iodideIn 2019 ,《Synthesis of Furoxans and Isoxazoles via Divergent [2 + 1 + 1 + 1] Annulations of Sulfoxonium Ylides and tBuONO》 was published in Organic Letters. The article was written by Tang, Zhonghe; Zhou, Yao; Song, Qiuling. The article contains the following contents:

A simple method for the divergent assembly of furoxans and isoxazoles in which the [2 + 1 + 1 + 1] annulation reaction of sulfoxonium ylides is reported. When the reaction was performed using t-BuONO as the nitrogen source without metal catalyst, the desired furoxans were obtained in decent yields with wide substrate scope. Isoxazoles bearing three carbonyl groups were achieved when the reaction was conducted using Cu(TFA)2 as catalyst. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Reference of Trimethylsulfoxonium iodide) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Reference of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com