Category: 172681-47-9

Related Products of 172681-47-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 172681-47-9, name is 2-Amino-6-iodotoluene, This compound has unique chemical properties. The synthetic route is as follows.

[00266] N-Acetyl-3-Iodo-2-Methyl Aniline. Charge a 5 L, 3 neck flask equipped with a mantle, stirrer, condenser, with 708 grams (5M) 3-Iodo-2-Methyl Aniline, followed by 700ml glacial acetic acid. Add in a stream of 520 grams (5.1M) acetic anhydride and allow the solution to come to a gentle reflux for an hour. The solution is allowed to cool and poured in a stream in a large container of 8L ice water. The product will crystallize immediately and is filtered and squeezed under vacuum and air-dried. Yield was 900 grams (Theoretical yield = 918 g).

The chemical industry reduces the impact on the environment during synthesis 2-Amino-6-iodotoluene. I believe this compound will play a more active role in future production and life.

Reference:
Patent; LATHAM, Keith, R.; WO2013/10102; (2013); A2;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 172681-47-9, name is 2-Amino-6-iodotoluene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. name: 2-Amino-6-iodotoluene

B2pin2 (140 mg, 0.55mmol, 1.1 equiv) and aniline 17 (117 mg, 0.5 mmol, 1.0 equiv) were weighed in a 25mL round-bottom flask. MeCN (2mL) and t-BuONO (86 mg, 0.75 mmol, 1.5 equiv) were then added insuccession. The resulting reaction solution was stirred for 3 h at 80 C (N2 evolution completed within 5 to15 min). The solution was then concentrated under reduced pressure, and the crude residue was purifiedby flash chromatography (silica gel, hexane/EtOAc = 40:1) to give pinacol boronate ester 18 (91.2 mg) in53% yield. The following deprotection and dean-stark procedure was same as preparing 1t.23

The synthetic route of 172681-47-9 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Li, Renhe; Liu, Feipeng; Dong, Guangbin; Chem; vol. 5; 4; (2019); p. 929 – 939;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 172681-47-9, The chemical industry reduces the impact on the environment during synthesis 172681-47-9, name is 2-Amino-6-iodotoluene, I believe this compound will play a more active role in future production and life.

N-Acetyl-3-Iodo-2-Methyl Aniline Charge a 5 L, 3 neck flask equipped with a mantle, stirrer, condenser, with 708 grams (5M) 3-Iodo-2-Methyl Aniline, followed by 700 ml glacial acetic acid. Add in a stream of 520 grams (5.1M) acetic anhydride and allow the solution to come to a gentle reflux for an hour. The solution is allowed to cool and poured in a stream in a large container of 8 L ice water. The product will crystallize immediately and is filtered and squeezed under vacuum and air-dried. Yield was 900 grams (Theoretical yield=918 g).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Amino-6-iodotoluene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Latham, Keith R.; (67 pag.)US2018/117164; (2018); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 172681-47-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 172681-47-9, name is 2-Amino-6-iodotoluene belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

To a mixture of 3-iodo-2-methylbenzenamine (4.45 g, 19.1 mmol, 1.0 equiv), bis(pinacolato)diboron (5.80 g, 22.91 mmol, 1.2 equiv), and potassium acetate (5.60 g, 57.3 mmol, 3.0 equiv) in DMSO (70 mL), was added dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium dichloromethane adduct (421 mg, 0.573 mmol, 0.03 equiv). The mixture was heated at 80 C. until the starting material was consumed. The solvent was removed in vacuo and the residue taken up in EtOAc (ca. 200 ml) and washed with water and brine. After drying with Na2SO4 and concentrating in vacuo, the residue was purified by silica gel chromatography (3:1 hexanes:EtOAc to 1:3 hexanes:EtOAc) to provide 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine. MS (M+H+) 234; Calculated for C13H20BNO2: 233.2

The synthetic route of 2-Amino-6-iodotoluene has been constantly updated, and we look forward to future research findings.