Category: 15854-87-2

In 2022,Mansoor Al Sarraf, Ahmad Azhar; H. Alsultany, Forat; H. Mahmoud, Zaid; S. Shafik, Shafik; I. Al, Zuhair; Sajjadi, Ahmad published an article in Synthetic Communications. The title of the article was 《Magnetic nanoparticles supported zinc (II) complex (Fe3O4@SiO2-Imine/Thio-Zn(OAc)2): a green and efficient magnetically reusable zinc nanocatalyst for synthesis of nitriles via cyanation of aryl iodides》.Product Details of 15854-87-2 The author mentioned the following in the article:

Herein we introduce a novel and reusable nanomagnetic copper catalyst (Fe3O4@SiO2-Imine/Thio-Zn(OAc)2) constructed by immobilizing Zn (II) complex on the surface of magnetic nanoparticles functionalized with Imine/Thio group. The structure of the as-constructed Fe3O4@SiO2-Imine/Thio-Zn(OAc)2 nanomaterial was well analyzed by a number of spectroscopic techniques including: FT-IR, SEM, TEM, EDX, XRD, VSM, AAS and ICP-OES. Exptl. studies have well revealed that Fe3O4@SiO2-Imine/Thio-Zn(OAc)2 nanomaterial is an ecofriendly and efficient nanocatalyst for synthesis of synthesis of nitriles via cyanation of aryl iodides. The grafting of the zinc catalyst to the surface of magnetic nanoparticles has increased the catalytic activity of the material and also simplified catalyst recovery from the reaction mixture by an external magnet. The Fe3O4@SiO2-Imine/Thio-Zn(OAc)2 nanocatalyst was readily recovered by simple magnetic decantation and can be reused seven cycles without considerable loss in catalytic activity. In the experimental materials used by the author, we found 4-Iodopyridine(cas: 15854-87-2Product Details of 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Product Details of 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Biosynthesis of Pd/MnO2 nanocomposite using Solanum melongena plant extract and its application for the one-pot synthesis of 5-substituted 1H-tetrazoles from aryl halides》 were Nasrollahzadeh, Mahmoud; Ghorbannezhad, Fatemeh; Sajadi, S. Mohammad. And the article was published in Applied Organometallic Chemistry in 2019. Electric Literature of C5H4IN The author mentioned the following in the article:

In this work, for the first time, Solanum melongena plant extract was used for the green synthesis of Pd/MnO2 nanocomposite via reduction of Pd(II) ions to Pd(0) and their immobilization on the surface of manganese dioxide (MnO2) nanoparticles (NPs) as an effective support. The synthesized nanocomposite was characterized by various anal. techniques such as Fourier transform IR (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), field emission SEM (FESEM), energy dispersive X-ray spectroscopy (EDS), and UV-Vis spectroscopy. Pd/MnO2 nanocomposite was used as a heterogeneous catalyst for the one-pot synthesis of 5-substituted 1H-tetrazoles from aryl halides containing various electron-donating or electron-withdrawing groups in the presence of K4[Fe(CN)6] as non-toxic cyanide source and sodium azide. The products were obtained in good yields via a simple methodol. and easy work-up. The nanocatalyst can be recycled and reused several times with no remarkable loss of activity. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Electric Literature of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Electric Literature of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Srilaxmi, Dandamudi; Reddy, Alugubelli Gopi; Sireesha, Reddymasu; Rao, Pasupuleti Visweswara; Kiran, M. Ravi; Kolli, Deepti; Rao, Mandava Venkata Basaveswara published an article in Russian Journal of General Chemistry. The title of the article was 《Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents》.Synthetic Route of C5H4IN The author mentioned the following in the article:

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives I (Ar = 4-OMeC6H4, 4-NCC6H4, 4-O2NC6H4, etc.) was prepared Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Synthetic Route of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Synthetic Route of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Mao, Shuai; Zhao, Yahao; Luo, Zixuan; Wang, Ruizhe; Yuan, Bo; Hu, Jianping; Hu, Linghao; Zhang, San-Qi; Ye, Xiaoxing; Wang, Mingliang; Chen, Zhengkai published an article in Frontiers in Chemistry (Lausanne, Switzerland). The title of the article was 《Metal-free photo-induced sulfidation of aryl iodide and other chalcogenation》.Quality Control of 4-Iodopyridine The author mentioned the following in the article:

A photo-induced C-S radical cross-coupling of aryl iodides and disulfides under transition-metal and external photosensitizer free conditions for the synthesis of aryl sulfides at room temperature has been presented, which features mild reaction conditions, broad substrate scope, high efficiency, and good functional group compatibility. The developed methodol. could be readily applied to forge C-S bond in the field of pharmaceutical and material science. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Quality Control of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Quality Control of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Angewandte Chemie, International Edition included an article by Iwasaki, Mitsuhiro; Shichibu, Yukatsu; Konishi, Katsuaki. Quality Control of 4-Iodopyridine. The article was titled 《Unusual Attractive Au-π Interactions in Small Diacetylene-Modified Gold Clusters》. The information in the text is summarized as follows:

It is well known that alkynes act as π-acids in the formation of complexes with metals. Authors found unprecedented attractive Au-π interactions in diacetylene-modified [core+exo]-type [Au8]4+ clusters. The 4-phenyl-1,3-butadiynyl-modified cluster has unusually short Au-Cα distances in the crystal structure, revealing the presence of attractive interactions between the coordinating CC moieties and the neighboring bitetrahedral Au6 core, which is further supported by IR and NMR spectra. Such weak interactions are not found in mono-acetylene-modified clusters, which indicates that they are specific for diacetylenic ligands. The attractive Au-π interactions are likely associated with the low energy of the π* orbital in the diacetylenic moieties, into which the valence electrons of the gold core may be back donated. The [Au8]4+ clusters show clear red-shifts of >10 nm with respect to the corresponding mono-acetylenic clusters in UV/Vis absorption bands, which indicates substantial electronic perturbation effects of the Au-π interactions. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Quality Control of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Quality Control of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Unraveling Concomitant Packing Polymorphism in Metallosupramolecular Polymers》 were Langenstroer, Anja; Kartha, Kalathil K.; Dorca, Yeray; Droste, Joern; Stepanenko, Vladimir; Albuquerque, Rodrigo Q.; Hansen, Michael Ryan; Sanchez, Luis; Fernandez, Gustavo. And the article was published in Journal of the American Chemical Society in 2019. Reference of 4-Iodopyridine The author mentioned the following in the article:

The phenomenon of polymorphism is ubiquitous in biol. systems and has been also observed in various types of self-assembled materials in solution and the solid state. In the field of supramol. polymers, different kinetic vs. thermodn. self-assembled species may exist in competition, a phenomenon termed as pathway complexity. In these examples, the transient kinetic species often has a very short lifetime and rapidly converts into the thermodn. product. The authors report a π-conjugated Pt(II) complex 1 that self-assembles in nonpolar medium into two supramol. polymers with distinct mol. packing (slipped (A) vs. pseudo-parallel (B)) that do not interconvert over time in a period of at least six months at room temperature Precise control of temperature, concentration and cooling rate enabled the authors to elucidate the stability conditions of both species through a phase diagram. Extensive exptl. studies and theor. calculations allowed the authors to elucidate the packing modes of both supramol. polymorphs A and B, which are stabilized by unconventional N-H···Cl-Pt and N-H···O-alkyl interactions, resp. Under a controlled set of conditions of cooling rate and concentration, both polymorphs can be isolated concomitantly in the same solution without interconversion. Only if A is annealed at high temperature for prolonged time, a slow transformation into B takes place via monomer formation. The authors’ system, which in many respects bears close resemblance to concomitant packing polymorphism in crystals, should help bridge the gap between crystal engineering and supramol. polymerization In the experimental materials used by the author, we found 4-Iodopyridine(cas: 15854-87-2Reference of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Reference of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C5H4INIn 2021 ,《Steric Hindrance in Metal Coordination Drives the Separation of Pyridine Regioisomers Using Rhodium(II)-Based Metal-Organic Polyhedra》 was published in Angewandte Chemie, International Edition. The article was written by Hernandez-Lopez, Laura; Martinez-Esain, Jordi; Carne-Sanchez, Arnau; Grancha, Thais; Faraudo, Jordi; Maspoch, Daniel. The article contains the following contents:

The physicochem. similarity of isomers makes their chem. separation through conventional techniques energy intensive. Herein, we report that, instead of using traditional encapsulation-driven processes, steric hindrance in metal coordination on the outer surface of RhII-based metal-organic polyhedra (Rh-MOPs) can be used to sep. pyridine-based regioisomers via liquid-liquid extraction Through mol. dynamics simulations and wet experiments, we discovered that the capacity of pyridines to coordinatively bind to Rh-MOPs is determined by the positions of the pyridine substituents relative to the pyridine nitrogen and is influenced by steric hindrance. Thus, we exploited the differential solubility of bound and non-bound pyridine regioisomers to engineer liquid-liquid self-sorting systems. As a proof of concept, we separated four different equimol. mixtures of regioisomers, including a mixture of the industrially relevant compounds 2-chloropyridine and 3-chloropyridine, isolating highly pure compounds in all cases. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Computed Properties of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Computed Properties of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthetic Route of C5H4INIn 2021 ,《Coupling of thiols and aromatic halides promoted by diboron derived super electron donors》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Franco, Mario; Vargas, Emily L.; Tortosa, Mariola; Cid, M. Belen. The article conveys some information:

Authors have proven that pyridine-boryl complexes can be used as superelectron donors to promote the coupling of thiols and aromatic halides through a SRN1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramol. electron transfer process. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Synthetic Route of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Synthetic Route of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Sajjadi, Mohaddeseh; Nasrollahzadeh, Mahmoud; Ghafuri, Hossein; Baran, Talat; Orooji, Yasin; Baran, Nuray Yilmaz; Shokouhimehr, Mohammadreza published an article in International Journal of Biological Macromolecules. The title of the article was 《Modified chitosan-zeolite supported Pd nanoparticles: A reusable catalyst for the synthesis of 5-substituted-1H-tetrazoles from aryl halides》.HPLC of Formula: 15854-87-2 The author mentioned the following in the article:

A novel heterogeneous catalyst was developed using chitosan-zeolite supported Pd nanoparticles (PdNPs@CS-Zeo) and used in an efficient synthesis of 5-substituted-1H-tetrazoles I [Ar = Ph, 4-pyridyl, 4-MeC6H4, etc.] from aryl halides with high yields for relatively short reaction times with an easy work-up procedure. In this method, highly effective and reusable PdNPs@CS-Zeo catalyst was used in the reaction of various aryl iodides/bromides with K4[Fe(CN)6] as a non-toxic cyanide source to catalyze the [2 + 3] cycloaddition of the corresponding aryl nitriles with NaN3 in the sequential one-pot preparation of 5-substituted-1H-tetrazoles I. The synthesized PdNPs@CS-Zeo nanocatalyst was characterized using XRD, FTIR, TEM, HRTEM, XPS, Raman, TG-DTG, ICP-OES, BET, and EDS mapping. Addnl., the nanocatalyst could be effectively separated by filtration and reused for multiple times without significant decrease of catalytic activity. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2HPLC of Formula: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. HPLC of Formula: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Reactivity Trends in the Gas-Phase Addition of Acetylene to the N-Protonated Aryl Radical Cations of Pyridine, Aniline, and Benzonitrile》 was written by Shiels, Oisin J.; Kelly, P. D.; Bright, Cameron C.; Poad, Berwyck L. J.; Blanksby, Stephen J.; da Silva, Gabriel; Trevitt, Adam J.. Reference of 4-Iodopyridine And the article was included in Journal of the American Society for Mass Spectrometry in 2021. The article conveys some information:

A key step in gas-phase polycyclic aromatic hydrocarbon (PAH) formation involves the addition of acetylene (or other alkyne) to σ-type aromatic radicals, with successive additions yielding more complex PAHs. A similar process can happen for N-containing aromatics In cold diffuse environments, such as the interstellar medium, rates of radical addition may be enhanced when the σ-type radical is charged. This paper investigates the gas-phase ion-mol. reactions of acetylene with nine aromatic distonic σ-type radical cations derived from pyridinium (Pyr), anilinium (Anl), and benzonitrilium (Bzn) ions. Three isomers are studied in each case (radical sites at the ortho, meta, and para positions). Using a room temperature ion trap, second-order rate coefficients, product branching ratios, and reaction efficiencies are measured. The rate coefficients increase from para to ortho positions. The second-order rate coefficients can be sorted into three groups: low, between 1 and 3 x 10-12 cm3 mol.-1 s-1 (3Anl and 4Anl); intermediate, between 5 and 15 x 10-12 cm3 mol.-1 s-1 (2Bzn, 3Bzn, and 4Bzn); and high, between 8 and 31 x 10-11 cm3 mol.-1 s-1 (2Anl, 2Pyr, 3Pyr, and 4Pyr); and 2Anl is the only radical cation with a rate coefficient distinctly different from its isomers. Quantum chem. calculations, using M06-2X-D3(0)/6-31++G(2df,p) geometries and DSD-PBEP86-NL/aug-cc-pVQZ energies, are deployed to rationalize reactivity trends based on the stability of prereactive complexes. The G3X-K method guides the assignment of product ions following adduct formation. The rate coefficient trend can be rationalized by a simple model based on the prereactive complex forward barrier height. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Reference of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Reference of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com