Category: 15854-87-2

In 2022,Xu, Xiaojia; Ji, Xiaoyu; Chen, Rui; Ye, Fangyuan; Liu, Shuaijun; Zhang, Shuo; Chen, Wei; Wu, Yongzhen; Zhu, Wei-Hong published an article in Advanced Functional Materials. The title of the article was 《Improving Contact and Passivation of Buried Interface for High-Efficiency and Large-Area Inverted Perovskite Solar Cells》.Recommanded Product: 4-Iodopyridine The author mentioned the following in the article:

Inverted-structured perovskite solar cells (PSCs) mostly employ poly-triarylamines (PTAAs) as hole-transporting materials (HTMs), which generally result in low-quality buried interface due to their hydrophobic nature, shallow HOMO levels, and absence of passivation groups. Herein, the authors molecularly engineer the structure of PTAA via removing alkyl groups and incorporating a multifunctional pyridine unit, which not only regulates energy levels and surface wettability, but also passivates interfacial trap-states, thus addressing above-mentioned issues simultaneously. By altering the linking-site on pyridine unit from ortho- (o-PY) to meta- (m-PY) and para-position (p-PY), they observed a gradually improved hydrophilicity and passivation efficacy, mainly owing to increased exposure of the pyridine-nitrogen as well as its lone electron pair, which enhances the contact and interactions with perovskite. The open-circuit voltage and power conversion efficiency (PCE) of inverted-structured PSCs based on these HTMs increased with the same trend. Consequently, the optimal p-PY as HTM enables facile deposition of uniform perovskite films without complicated interlayer optimizations, delivering a remarkably high PCE exceeding 22% (0.09 cm2). Moreover, when enlarging device area tenfold, a comparable PCE of over 20% (1 cm2) can be obtained. These results are among the highest efficiencies for inverted PSCs, demonstrating the high potential of p-PY for future applications. After reading the article, we found that the author used 4-Iodopyridine(cas: 15854-87-2Recommanded Product: 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Recommanded Product: 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Du, Yijun; Gou, Faliang; Gao, Danning; Liu, Zhifeng; Shao, Linjun; Qi, Chenze published an article in 2021. The article was titled 《Palladium nanoparticles encapsulated in polyimide nanofibers: An efficient and recyclable catalyst for coupling reaction》, and you may find the article in Applied Organometallic Chemistry.Related Products of 15854-87-2 The information in the text is summarized as follows:

In this study, palladium-encapsulated poly(amic acid) (Pd@PAA) nanofibers were prepared by electrospinning, followed by thermal imidization to synthesize palladium-encapsulated polyimide (Pd@PI) nanofibers. SEM images confirmed the preparation of uniform and smooth Pd@PAA and Pd@PI nanofibers. Thermogravimetric anal. (TGA) results reveal that the Pd@PI nanofibers possessed excellent thermal stability. The dispersion of palladium nanoparticles in the polyimide nanofibers was characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD). The catalysis results show that this Pd@PI fibrous catalyst was very efficient to catalyze the cross-coupling reactions of aromatic iodides with Bu acrylate (Heck reaction) or phenylboronic acid derivatives (Suzuki reaction) to afford the desired products in good to excellent yields. Moreover, the Pd@PI catalyst could be easily separated and recovered from the reaction mixture by simple filtration due to the regular fibrous structure and reused for 10 times for both Heck and Suzuki reactions without obvious loss of its initial catalytic activity. Thus, the Pd@PI nanofiber catalyst holds great potential in chem. industry in terms of its excellent catalytic activity and stability. In the experiment, the researchers used 4-Iodopyridine(cas: 15854-87-2Related Products of 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Related Products of 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shen, Yifeng; Xu, Congjun; Chen, Jie; Guan, Zilin; Huang, Yanjuan; Zeng, Zishan; Xu, Xiaoyu; Tan, Xiaomin; Zhao, Chunshun published an article in 2021. The article was titled 《Phototriggered Self-Adaptive Functionalized MOC-Based Drug Delivery Platform Promises High Antitumor Efficacy》, and you may find the article in Advanced Healthcare Materials.HPLC of Formula: 15854-87-2 The information in the text is summarized as follows:

Due to their great stability and special cavities, metal-organic cages (MOCs) are increasingly considered as promising nanocarriers for drug delivery. However, the size and surface dilemmas restrict their further biomedical applications. The ultrasmall size of MOCs facilitates tumor penetration but suffers from quick clearance and poor accumulation at the tumor site. Hydrophobicity of MOC surfaces improves internalization into tumor cells while causing low blood circulation time as well as poor biocompatibility. Therefore, it remains challenging for the MOC-based drug delivery nanoplatform to realize high therapeutic efficacy because it requires different or even opposite dimensions and surface characteristics in different steps of circulation, penetration, accumulation, and internalization processes. In this study, an unprecedented phototriggered self-adaptive platform (ZnPc@polySCage) is developed by integrating functionalized MOCs and a photodynamic therapy based reactive oxygen species responsive strategy to realize high-efficiency tumor-specific therapy. ZnPc@polySCage remains hydrophilic and stealthy during circulation, and retains its small original size for tumor penetration, while transforming to a larger size for effective accumulation and hydrophobic for enhanced internalization under laser irradiation in tumor tissue. With these essential transitions, ZnPc@polySCage demonstrates prominent antitumor effects. Overall, the work provides an advantageous strategy for functional MOC-based platforms and biomedical applications. In addition to this study using 4-Iodopyridine, there are many other studies that have used 4-Iodopyridine(cas: 15854-87-2HPLC of Formula: 15854-87-2) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.HPLC of Formula: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Koteswaraiah, M.; Praveen, Ch; reddy, Thummaluru Veera; Raveendrareddy, Gopireddy; Srinivas, Uppalanchi published an article in 2022. The article was titled 《Design, synthesis and biological evaluation of aryl and hetero-aryl linked thieno[3,2-d]pyrimidine derivatives as anticancer agents》, and you may find the article in Chemical Data Collections.COA of Formula: C5H4IN The information in the text is summarized as follows:

A new library of different aryl and heteroaryl linked thieno[3,2-d]pyrimidine derivatives I [Ar = 4-MeC6H4, 4-MeOC6H4, 4-O2NC6H4, etc.] were synthesized and characterized by 1HNMR, 13CNMR and mass spectroscopic techniques. Further, these were evaluated for their anticancer potentials against the selected four human cancer cell lines including PC3 (prostate cancer), A549 (lung cancer), MCF-7 (breast cancer) and DU-145 (prostate cancer). The obtained results suggested that four compounds I [Ar = 3,4,5-tri-MeOC6H2, 3,5-di-MeOC6H3, 4-pyridyl, 4-pyrazyl] exhibited more potent anticancer properties. Predominantly, two compounds I [Ar = 3,4,5-tri-MeOC6H2, 4-pyridyl] demonstrated most capable anticancer activity of the library. In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2COA of Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.COA of Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Recommanded Product: 4-IodopyridineIn 2022 ,《Synthesis and Mechanistic Investigation of Bipyrazolo[1,5-a]pyridines via Palladium-Catalyzed Cross-Dehydrogenative Coupling of Pyrazolo[1,5-a]pyridines》 appeared in Journal of Organic Chemistry. The author of the article were Hsiao, Pu-Yen; Chang, Rong; Sue, Andrew C.-H.; Chu, Jean-Ho; Liao, Guan-Wei; Lee, Yi-Hsin; Huang, Jui-Yang. The article conveys some information:

The synthesis of a range of 3,3′-bipyrazolo[1,5-a]pyridine derivatives via direct cross-dehydrogenative coupling of pyrazolo[1,5-a]pyridine precursors was herein presented. This simple and efficient methodol. involving palladium(II)-catalyzed C-H bond activation showed good functional group tolerance and product yield (up to 94%). Through the mechanistic insights gained from both kinetic isotope effect exptl. studies and d. functional theory calculations, a plausible reaction mechanism was outlined. Furthermore, subsequent derivatizations of the resulting 7,7′-diaryl-3,3′-bipyrazolo[1,5-a]pyridines, executed by performing palladium-mediated ortho C-H bond activation followed by hypervalent iodine-induced chlorination, rendered this series of compounds more extended π-conjugation and twisted conformations. The study on these bipyrazolo[1,5-a]pyridine-based luminogens provided new opportunities for tailor-made organic luminescent materials.4-Iodopyridine(cas: 15854-87-2Recommanded Product: 4-Iodopyridine) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Recommanded Product: 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bai, Guoyun; O’Connell, Thomas N.; Brodney, Michael A.; Butler, Christopher R.; Czabaniuk, Lara C.; Gilbert, Adam M.; LaChapelle, Erik A.; Li, Chao; McAllister, Laura A.; Ogilvie, Kevin; Philippe, Laurence; Salomon-Ferrer, Romelia; Shapiro, Michael J.; Starr, Jeremy T.; Uccello, Daniel P.; Withka, Jane M.; Yan, Jiangli; Brown, Matthew F. published an article in 2021. The article was titled 《Intramolecular Ring-Opening Decomposition of Aryl Azetidines》, and you may find the article in ACS Medicinal Chemistry Letters.Safety of 4-Iodopyridine The information in the text is summarized as follows:

The ring strain present in azetidines can lead to undesired stability issues. Herein, we described a series of N-substituted azetidines which undergo an acid-mediated intramol. ring-opening decomposition via nucleophilic attack of a pendant amide group. Studies were conducted to understand the decomposition mechanism enabling the design of stable analogs. In addition to this study using 4-Iodopyridine, there are many other studies that have used 4-Iodopyridine(cas: 15854-87-2Safety of 4-Iodopyridine) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Safety of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

HPLC of Formula: 15854-87-2In 2019 ,《In situ Investigations of a Proton Trap Material: A PEDOT-Based Copolymer with Hydroquinone and Pyridine Side Groups Having Robust Cyclability in Organic Electrolytes and Ionic Liquids》 appeared in ACS Applied Energy Materials. The author of the article were Aakerlund, Lisa; Emanuelsson, Rikard; Hernandez, Guiomar; Ruiperez, Fernando; Casado, Nerea; Brandell, Daniel; Stroemme, Maria; Mecerreyes, David; Sjoedin, Martin. The article conveys some information:

A conducting redox polymer based on PEDOT with hydroquinone and pyridine pendant groups is reported and characterized as a proton trap material. The proton trap functionality, where protons are transferred from the hydroquinone to the pyridine sites, allows for utilization of the inherently high redox potential of the hydroquinone pendant group (3.3 V vs. Li0/+) and sustains this reaction by trapping the protons within the polymer, resulting in proton cycling in an aprotic electrolyte. By disconnecting the cycling ion of the anode from the cathode, the choice of anode and electrolyte can be extensively varied and the proton trap copolymer can be used as cathode material for all-organic or metal-organic batteries. In this study, a stable and nonvolatile ionic liquid was introduced as electrolyte media, leading to enhanced cycling stability of the proton trap compared to cycling in acetonitrile, which is attributed to the decreased basicity of the solvent. Various in situ methods allowed for in-depth characterization of the polymer’s properties based on its electronic transitions (UV-vis), temperature-dependent conductivity (bipotentiostatic CV-measurements), and mass change (EQCM) during the redox cycle. Furthermore, FTIR combined with quantum chem. calculations indicate that hydrogen bonding interactions are present for all the hydroquinone and quinone states, explaining the reversible behavior of the copolymer in aprotic electrolytes, both in three-electrode setup and in battery devices. These results demonstrate the proton trap concept as an interesting strategy for high potential organic energy storage materials. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2HPLC of Formula: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.HPLC of Formula: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C5H4INIn 2021 ,《One-Pot Synthesis of 11C-Labelled Primary Benzamides via Intermediate [11C]Aroyl Dimethylaminopyridinium Salts》 appeared in Chemistry – A European Journal. The author of the article were Ferrat, Melodie; Dahl, Kenneth; Schou, Magnus. The article conveys some information:

Electrophilic 11C-labeled aroyl dimethylaminopyridinium salts, obtained in situ by carbonylative cross-coupling of aryl halides with [11C]carbon monoxide, were prepared for the first time and shown to be valuable intermediates in the synthesis of primary [11C]benzamides. The methodol. furnished a set of benzamide model compounds, including the two poly (ADP-ribose) polymerase (PARP) inhibitors niraparib and veliparib, in moderate to excellent radiochem. yields. In addition to providing a convenient and practical route to primary [11C]benzamides, the current method paves the way for future application of [11C]aroyl dimethylaminopyridinium halide salts in positron emission tomog. (PET) tracer synthesis. The experimental process involved the reaction of 4-Iodopyridine(cas: 15854-87-2Computed Properties of C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Computed Properties of C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Molecular Bending: An Important Factor Affecting the Packing of Self-Assembled Monolayers of Triptycene-Based Molecular Rods on a (111) Gold Surface》 was written by Roncevic, Igor; Kaletova, Eva; Varga, Katarina; Cisarova, Ivana; Bastl, Zdenek; Jiang, Jyh-Chiang; Kaleta, Jiri. Formula: C5H4INThis research focused ontriptycene mol rod bending self assembled monolayer gold surface. The article conveys some information:

The present study has identified mol. bending as an important factor that has a profound effect on the self-assembly of originally rod-shaped organic mols. on a (111) gold surface. This was demonstrated on three specifically designed rigid mol. rods carrying archetypal anchoring groups (pyridyl units and thiols) on one terminus. These rods were used to prepare corresponding self-assembled monolayers (SAMs), and a combination of various anal. techniques revealed that originally straight mol. rods that were bent once adsorbed on a metallic surface, acquiring a characteristic “”J-shape””. Extensive d. functional theory calculations, including in silico reconstruction of such SAMs on (111) gold, clearly confirmed exptl. observations. In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Safety of 4-IodopyridineIn 2022 ,《Synthesis of Thioalkynes by Desilylative Sonogashira Cross-Coupling of Aryl Iodides and 1-Methylthio-2-(trimethylsilyl)ethyne》 was published in European Journal of Organic Chemistry. The article was written by Cao, Yang; Huang, Yang; Blakemore, Paul R.. The article contains the following contents:

1-Methylthio-2-arylethynes ArC≡CSMe [Ar = Ph, 1-naphthyl, 4-MeC6H4, etc.] were prepared in typically good to excellent yields from aryl iodides and 1-methylthio-2-(trimethylsilyl)ethyne by a desilylative Sonogashira process employing Pd(PPh3)2Cl2 (1 mol %), CuI (10 mol %) and K2CO3 (6 equiv) in MeOH-Et3N-THF (1:2:2) at rt for 16 h (16 examples, 31-96% yield). Thienyl and pyridyl iodides (all regioisomers) were similarly converted to 1-methylthio-2-heteroarylethynes ArC≡CSMe [Ar = 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-thienyl, 3-thienyl] (5 examples, 54-82% yield). The process was extended with similar results to comparable thioalkynes PhC≡CSR [R = n-Bu, cyclohexyl, 4-MeC6H4] substituted on sulfur. The experimental process involved the reaction of 4-Iodopyridine(cas: 15854-87-2Safety of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Safety of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com