Category: 15854-87-2

In 2022,Zhao, Zesheng; Wang, Jie; Zhang, Xiaoli; Lin, Taofeng; Ren, Jianwei; Pang, Wan published an article in Tetrahedron Letters. The title of the article was 《Pd nanoparticles embedded into MOF-808: An efficient and reusable catalyst for Sonogashira and Heck cross-coupling reactions》.Application In Synthesis of 4-Iodopyridine The author mentioned the following in the article:

In this work, the Pd@MOF-808 composite was prepared to effectively catalyze the Sonogashira and Heck reactions without the presence of organic phosphine ligands. The results showed that the developed catalyst provided an environment-friendly reaction condition for these two reactions with the existence of a variety of functional groups and substrates. In addition, the Pd@MOF-808 catalyst could be easily recovered and reused for up to 5 times with less deterioration of catalytic performance. In the experimental materials used by the author, we found 4-Iodopyridine(cas: 15854-87-2Application In Synthesis of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Application In Synthesis of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

HPLC of Formula: 15854-87-2In 2021 ,《Construction of supramolecular hyperbranched polymers based on a tetrathiafulvalene derivative: Self-assembly and charge transfer interaction with TCNQ》 was published in Tetrahedron Letters. The article was written by Li, Xing-Long; Qin, Jie; Jiang, Man; Chen, Meng-Ning; Wang, Rong-Zhou; Yu, Shengsheng; Wang, Hai-Ying; Xing, Ling-Bao. The article contains the following contents:

In the present work, a four naphthyl-armed tetrathiafulvalene derivative (TTFB) was designed and synthesized through one-step reaction. Based on the host-guest interaction between naphthyl and cucurbit[8]uril (CB[8]), supramol. hyperbranched polymers (SHPs) can be constructed in water, depending on hydrogen NMR spectra, UV-vis absorption spectroscopy and diffusion-ordered NMR spectroscopy. The self-assembly properties of the SHPs were further investigated by zeta potential analyzer, dynamic laser light scattering and transmission electron microscopy measurements, which exhibited pos. charged spherical structures with the diameter at ∼120 nm. More interestingly, the SHPs can interact with TCNQ (7,7,8,8-tetracyanoquinodimethane) to form charge transfer complexes through charge transfer interaction. Meanwhile, the self-assembly structures can be transformed from spherical structures to crosslinked nanoparticles in the charge transfer complexes state. The experimental part of the paper was very detailed, including the reaction process of 4-Iodopyridine(cas: 15854-87-2HPLC of Formula: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.HPLC of Formula: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Sustainable and recyclable heterogenous palladium catalysts from rice husk-derived biosilicates for Suzuki-Miyaura cross-couplings, aerobic oxidations and stereoselective cascade carbocyclizations》 was written by Afewerki, Samson; Franco, Ana; Balu, Alina M.; Tai, Cheuk-Wai; Luque, Rafael; Cordova, Armando. Product Details of 15854-87-2 And the article was included in Scientific Reports in 2020. The article conveys some information:

Abstract: A new eco-friendly approach for the preparation of sustainable heterogeneous palladium catalysts from rice husk-derived biogenic silica (RHP-Si and RHU-Si). The designed heterogeneously supported palladium species (RHP-Si-NH2-Pd and RHU-Si-NH2-Pd) were fully characterized and successfully employed as catalysts for various chem. transformations (C-C bond-forming reactions, aerobic oxidations and carbocyclizations). Suzuki-Miyaura transformations were highly efficient in a green solvent system (H2O:EtOH (1:1) with excellent recyclability, providing the cross-coupling products with a wide range of functionalities in high isolated yields (up to 99%). Palladium species (Pd(0)-nanoparticles or Pd(II)) were also efficient catalysts in the green aerobic oxidation of an allylic alc. and a co-catalytic stereoselective cascade carbocyclization transformation. In the latter case, a quaternary stereocenter was formed with excellent stereoselectivity (up to 27:1 dr). In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2Product Details of 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Product Details of 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Horan, Alexandra M.; Duong, Vincent K.; McGarrigle, Eoghan M. published their research in Organic Letters in 2021. The article was titled 《Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts》.Formula: C5H4IN The article contains the following contents:

Herein ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts I (R = H, Br, Me, trifluoromethyl; R1 = H, OMe, CN, Br, etc.; R2 = H, trifluoromethyl; R3 = H, Me; R2R3 = -(CH=CH-CH=CH)-) and phenyl(pyrimidin-2-yl)(p-tolyl)sulfonium trifluoromethanesulfonate are reported. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages including 2,4′-bipyridines, 2,3′-bipyridines, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes II (R4 = 2-fluoropyridin-4-yl, pyrazin-2-yl, dimethyl-1,2-oxazol-4-yl, 1-benzothiophen-2-yl, etc.). The methodol. was successfully applied to the synthesis of the natural products caerulomycin A and E. In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Zhou, Xian-Chao; Wu, Le-Xiong; Wang, Xue-Zhi; Lai, Ya-Liang; Ge, Ying-Ying; Su, Juan; Zhou, Xiao-Ping; Li, Dan published an article in Inorganic Chemistry. The title of the article was 《Self-Assembly of a Pd4Cu8L8 Cage for Epoxidation of Styrene and Its Derivatives》.Application In Synthesis of 4-Iodopyridine The author mentioned the following in the article:

Herein the authors report a discrete heterometallic Pd4Cu8L8 cage with a tubular structure, L = N,N’-(propane-1,3-diyl)bis(1-(1-(pyridin-4-yl)-1H-imidazol-4-yl))methanimine, which was synthesized by the assembly of copper metallo ligands and PdII ions in a stepwise manner. The Pd4Cu8L8 cage has been unequivocally characterized by single-crystal X-ray diffraction, electrospray ionization-mass spectroscopy, and energy dispersive spectroscopy. The cage showed excellent catalytic activity in the epoxidation of styrene and its derivatives under conditions without using addnl. solvent, providing potential material for catalyzing the oxidation reactions. After reading the article, we found that the author used 4-Iodopyridine(cas: 15854-87-2Application In Synthesis of 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Application In Synthesis of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Construction of Highly Emissive Pt(II) Metallacycles upon Irradiation》 were Qin, Yi; Zhang, Ying; Yin, Guangqiang; Wang, Yuxuan; Zhang, Changwei; Chen, Lijun; Tan, Hongwei; Li, Xiaopeng; Xu, Lin; Yang, Haibo. And the article was published in Chinese Journal of Chemistry in 2019. Formula: C5H4IN The author mentioned the following in the article:

Photoswitchable or photoactivatable fluorescent species have been found wide applications within supramol. chem. and materials science. In this study, we successfully constructed two highly emissive Pt(II) metallacycles from the diarylethene ligands via coordination-driven self-assembly. Different from the most known fluorescent metallacycles, the obtained metallacycles have displayed “”turn-on”” fluorescence switching. They are non-fluorescent in solution, but they emit highly yellow or orange fluorescence under UV irradiation The metallacycles were well characterized by 1H NMR, 31P NMR and ESI-TOF-MS. The photochromic properties of the resultant metallacycles were investigated by 1H NMR, 31P NMR, UV/Vis spectrum and fluorescence spectrum. Notably, NMR studies revealed that these two metallacycles featured excellent cyclization efficiency (90% conversion efficiency). Moreover, the closed-ring isomers of the metallacycles displayed relatively high quantum yield (ΦF = 0.5). DFT simulations demonstrated that the antiparallel configuration of the diarylethene ligand had an angle closed to 120°, which was more stable in energy compared to the parallel configuration, thus allowing for the facile construction of highly emissive metallacycles. We believe that such highly emissive metallacycles which are in-situ prepared upon irradiation can be used as new fluorescence materials for sensing and bioimaging in the future. The experimental part of the paper was very detailed, including the reaction process of 4-Iodopyridine(cas: 15854-87-2Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Leushukou, Andrei A.; Krech, Anastasiya V.; Hurski, Alaksiej L. published an article in Organic Letters. The title of the article was 《Visible-Light-Promoted Nickel-Catalyzed Cross-Coupling of Alkyltitanium Alkoxides with Aryl and Alkenyl Halides》.SDS of cas: 15854-87-2 The author mentioned the following in the article:

The reported alkyltitanium alkoxides generated in situ from Grignard reagents and Ti(OiPr)4 undergone a photocatalyst-free nickel-catalyzed cross-coupling with organic halides upon irradation with blue light. Mechanistic studies suggested that the reaction proceeds through radical intermediates formed by photochem. decomposition of the alkyltitanium reagents. Various aryl, heteroaryl, and vinyl halides was efficiently alkylated under the reported conditions, including those containing ester and amide groups. The experimental process involved the reaction of 4-Iodopyridine(cas: 15854-87-2SDS of cas: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.SDS of cas: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Allosteric regulation of rotational, optical and catalytic properties within multicomponent machinery》 was written by Saha, Suchismita; Ghosh, Amit; Paululat, Thomas; Schmittel, Michael. Category: iodides-buliding-blocksThis research focused ontransition metal porphyrin multicomponent nanorotor supramol structure preparation; Michael addition catalytic activity transition metal porphyrin complex; fluorescence transition metal porphyrin multicomponent nanorotor complex. The article conveys some information:

The reversible transformation of multicomponent nanorotors (ROT-1, k298 = 44 kHz or ROT-2, k298 = 61 kHz) to the “”dimeric”” supramol. structures (DS-1 or DS-2, k298 = 0.60 kHz) was triggered by a stoichiometric chem. stimulus. Simple coordination changes at the central phenanthroline of the mol. device by altering metal ions (Cu+ → Zn2+) or stoichiometry (Cu+, 1 equiv → 0.5 equiv) affected the terminal zinc(II) porphyrin units, the active sites within the machinery, changing rotational, catalytic and optical properties. In presence of added pyrrolidine, the nanorotor ROT-1 was inactive for catalysis whereas formation of the dimeric supramol. structures DS-1 initiated a Michael addition reaction by releasing the organo-catalyst from the porphyrin sites. This catalytic machinery (ROT-1 → DS-1) proved to reproducibly work over two full cycles using allosteric OFF/ON control of catalysis.4-Iodopyridine(cas: 15854-87-2Category: iodides-buliding-blocks) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure-activity relationship, toxicity, and mechanism of action》 was written by da Rosa, Rafael; Dambros, Bibiana Paula; Hoehr de Moraes, Milene; Grand, Lucie; Jacolot, Maiwenn; Popowycz, Florence; Steindel, Mario; Schenkel, Eloir Paulo; Campos Bernardes, Lilian Sibelle. Application of 15854-87-2This research focused onTrypanosoma toxicity structure activity relationship; Antiparasitic; Isoxazole; Mitochondrial dysfunction; Natural products; Neglected tropical diseases; Oxazole; T. cruzi. The article conveys some information:

Chem. scaffolds of natural products have historically been sources of inspiration for the development of novel mols. of biol. relevance, including hit and lead compounds To identify new compounds active against Trypanosoma cruzi, we designed and synthesized 46 synthetic derivatives based on the structure of two classes of natural products: THF lignans (Series 1) and oxazole alkaloids (Series 2). Compounds were screened in vitro using a cellular model of T. cruzi infection. In the first series of compounds, 11 derivatives of hit compound 5 (EC50 = 1.1 μM) were found to be active; the most potent (7, 8, and 13) had EC50 values of 5.1-34.2 μM. In the second series, 17 analogs were found active at 50 μM; the most potent compounds (47, 49, 59, and 63) showed EC50 values of 24.2-49.1 μM. Active compounds were assessed for selectivity, hemocompatibility, synergistic potential, effects on mitochondrial membrane potential, and inhibitory effect on trypanothione reductase. All active compounds showed low toxicity against uninfected THP-1 cells and human erythrocytes. The potency of compounds 5 and 8 increased steadily in combination with benznidazole, indicating a synergistic effect. Furthermore, compounds 8, 47, 49, 59, and 63 inhibited parasitic mitochondria in a dose-dependent manner. Although increased reactive oxygen species levels might lead to mitochondrial effects, the results indicate that the mechanism of action of the compounds is not dependent on trypanothione reductase inhibition. In silico calculation of chem. descriptors and principal component anal. showed that the active compounds share common chem. features with other trypanocidal mols. and are predicted to have a good ADMET profile. Overall, the results suggest that the compounds are important candidates to be further studied for their potential against T. cruzi. In addition to this study using 4-Iodopyridine, there are many other studies that have used 4-Iodopyridine(cas: 15854-87-2Application of 15854-87-2) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Application of 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Zinc (II) complex immobilized on the surface of magnetic nanoparticles modified with phenanthroline: A novel and efficient nanomagnetic reusable catalyst for cross-coupling reaction of aryl iodides with terminal aromatic alkynes》 was written by Raya, Indah; Abdalkareem Jasim, Saade; Hashim Abdulkadhim, Adnan; Hashem Abbud, Luay; Sharma, Himanshu. SDS of cas: 15854-87-2This research focused onzinc magnetic nanoparticle catalyst Sonogashira crosscoupling catalyst aryliodide arylalkyne. The article conveys some information:

A novel and green nanomagnetic Zn catalyst were fabricated via the immobilization of Zn (II) complex on the surface of magnetic nanoparticles modified with phenanthroline (MNPs-Phen-Zn(II)). The structure of MNPs-Phen-Zn(II) nanomaterial was characterized by spectroscopic techniques including FTIR spectroscopy, SEM, TEM, EDX, XRD, VSM, and ICP-OES. The resulting Zn nanomagnetic catalyst was shown high catalytic activity for the synthesis of disubstituted alkynes via C(sp2)-C(sp) cross-coupling reactions of alkynes with aryl iodides under eco-friendly conditions. It is the first report on the use of Zn nanomagnetic catalyst for the Sonogashira type cross-coupling reaction of alkynes with aryl iodides in the absence of added Pd and Cu sources. The simple preparation of the catalyst from com. available materials, excellent chemoselectivity, easy separation of products, and straightforward recovery and reusability of the catalyst with unaltered activity make the procedure a green and practical method. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2SDS of cas: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.SDS of cas: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com